Click here to switch to the map view.

The map label for this gene is panC/cmk

Identifier: 113476387

GI number: 113476387

Start: 4340289

End: 4341875

Strand: Reverse

Name: panC/cmk

Synonym: Tery_2799

Alternate gene names: 113476387

Gene position: 4341875-4340289 (Counterclockwise)

Preceding gene: 113476388

Following gene: 113476386

Centisome position: 56.02

GC content: 35.6

Gene sequence:

>1587_bases
ATGCGTTTATTTACAACTATTGCAGGGTTAAACTGCTACTTAAATTTACTGCGAAATGAACAAAAAAAATCTCCAGATAC
TATTGGTTTAGTTCCGACAATGGGAGCTTTGCACAAAGGACATTTAAGTTTAATTAAACGTGCAAGAGAAGAAAATACGA
TTACGGTTGTCAGCATTTTTATTAATCCTTTACAGTTTGCTCCTAGGGAAGATTTTAAAGAATATCCTCGACAGTTAGAA
ATAGATAAAGAATTTTGTGAAAAGGAAGGAGTAGACGTAATTTTTGCTCCCACTCCTGAAACAATGGGTATGAAAAATGC
TTTATCTACTGATGCTCAAGACTCTACAACTACAGTTGTTTCTCCATCTCATATGACATCAATTATGTGTGGAGTTTCTC
GACCGAATTTTTTTCAGGGAGTGGCAACAATTGTAACTAAGTTATTGAATATAGTTAAACCAAATAATGCTTATTTTGGG
CAAAAAGATGCTCAACAGTTGGCAATTATTAAGCAATTGGTTAAAGACCTGAGTTTGCCAGTTAATATTGTTTATTGCCC
AATAATTCGAGAAGCTTCAGGATTAGCTATTAGTTCTCGGAATCAATATTTAACTCCTGAACAAAAGGAGCAAGCTTCTA
TGCTTTATGCTTCTCTTTGTTATGGTAGAAAAATATTTTTAGAGAATCAAGATACCCCAAATATTTTAGAAACAGTTGAA
AATGCTGTTAAGGAAAAGTTAGCATCTCAACCAGTATTAAAACTAGAGTATTTGGAAATAGTTGACCCTGAGACTTTAAA
ACCTTTAGAAAATATTCAAAATATAGGTTTATTAGCGATCGCTGCTTATATTGGCTCTTGCCGTTTAATAGATAATATAC
TTTTGAGAAACCGTAAACCTATCATTGCAATTGATGGGCCTGCTGGTGCGGGGAAATCTACAGTTACCAAATTAGTGGGA
CAAAGCCTAGGACTTTTGTACTTGGACACAGGAGCAATGTACCGGGCAGTAACATGGATGGTATTACAATCTGGTGTGCC
AGTTACCGACCAAGCTCAGGTAGCAGAATTAGTAAGTCAATGCCAAATCAGCTTTAATAGTCCTGAAAATAACCATGTCG
TAATCAATGGCCAAGATGTCACAGTAGCAATTCGGAGTAGGGAAGTAACAAATAATGTTTCAATTGTTGCAGCCCAGCCT
ACAGTGAGGTATTTTATGGTCAAACAACAACAACAATTTGGCGCTAAAGGAGGAATAGTAGCAGAAGGACGAGATATTGG
CTCTCATGTTTTTCCAAATGCTGAACTAAAGATTTTTTTAACCGCTTCGCTAAAAGAGCGATCGCGACGGCGACTAGTTG
AATTAAAACAGAAAGGTCAAACGAACATCAGCTTAGAAGAAGTAGAAAAAGAGATTATTTGTCGTGACCAAAAAGATACT
AACCGAAAAATTTCTCCCTTGCGAAAATCTTCAGATGCTGTTGAAATTAGTACAGATGGTTTAAGCATAGGTGAGGTCAC
TCAAAAAATTGTAGATATTTTTAAGACAACTTGCTATGGAAAATCCTCAGTAAATAACATAATTTAA

Upstream 100 bases:

>100_bases
ATTTAGAAAGGGATGTCAATGGTTAATTGATTTCTAATTTTTTAGAGTAGAATAAACATTGCTATAATAAATTCAAAATT
GCTTATATTGGTCAAGAAAA

Downstream 100 bases:

>100_bases
ATTAACGTCTAATTTTATGAGGAAAATTAATTAAAAAAATTAAAAATAAGTCAAAATATTGTATACATTGCTCAAAAATT
ATCAAGTCATTAAATTTATT

Product: bifunctional pantoate ligase/cytidylate kinase

Products: NA

Alternate protein names: Pantothenate synthetase; PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme; Cytidylate kinase; CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MRLFTTIAGLNCYLNLLRNEQKKSPDTIGLVPTMGALHKGHLSLIKRAREENTITVVSIFINPLQFAPREDFKEYPRQLE
IDKEFCEKEGVDVIFAPTPETMGMKNALSTDAQDSTTTVVSPSHMTSIMCGVSRPNFFQGVATIVTKLLNIVKPNNAYFG
QKDAQQLAIIKQLVKDLSLPVNIVYCPIIREASGLAISSRNQYLTPEQKEQASMLYASLCYGRKIFLENQDTPNILETVE
NAVKEKLASQPVLKLEYLEIVDPETLKPLENIQNIGLLAIAAYIGSCRLIDNILLRNRKPIIAIDGPAGAGKSTVTKLVG
QSLGLLYLDTGAMYRAVTWMVLQSGVPVTDQAQVAELVSQCQISFNSPENNHVVINGQDVTVAIRSREVTNNVSIVAAQP
TVRYFMVKQQQQFGAKGGIVAEGRDIGSHVFPNAELKIFLTASLKERSRRRLVELKQKGQTNISLEEVEKEIICRDQKDT
NRKISPLRKSSDAVEISTDGLSIGEVTQKIVDIFKTTCYGKSSVNNII

Sequences:

>Translated_528_residues
MRLFTTIAGLNCYLNLLRNEQKKSPDTIGLVPTMGALHKGHLSLIKRAREENTITVVSIFINPLQFAPREDFKEYPRQLE
IDKEFCEKEGVDVIFAPTPETMGMKNALSTDAQDSTTTVVSPSHMTSIMCGVSRPNFFQGVATIVTKLLNIVKPNNAYFG
QKDAQQLAIIKQLVKDLSLPVNIVYCPIIREASGLAISSRNQYLTPEQKEQASMLYASLCYGRKIFLENQDTPNILETVE
NAVKEKLASQPVLKLEYLEIVDPETLKPLENIQNIGLLAIAAYIGSCRLIDNILLRNRKPIIAIDGPAGAGKSTVTKLVG
QSLGLLYLDTGAMYRAVTWMVLQSGVPVTDQAQVAELVSQCQISFNSPENNHVVINGQDVTVAIRSREVTNNVSIVAAQP
TVRYFMVKQQQQFGAKGGIVAEGRDIGSHVFPNAELKIFLTASLKERSRRRLVELKQKGQTNISLEEVEKEIICRDQKDT
NRKISPLRKSSDAVEISTDGLSIGEVTQKIVDIFKTTCYGKSSVNNII
>Mature_528_residues
MRLFTTIAGLNCYLNLLRNEQKKSPDTIGLVPTMGALHKGHLSLIKRAREENTITVVSIFINPLQFAPREDFKEYPRQLE
IDKEFCEKEGVDVIFAPTPETMGMKNALSTDAQDSTTTVVSPSHMTSIMCGVSRPNFFQGVATIVTKLLNIVKPNNAYFG
QKDAQQLAIIKQLVKDLSLPVNIVYCPIIREASGLAISSRNQYLTPEQKEQASMLYASLCYGRKIFLENQDTPNILETVE
NAVKEKLASQPVLKLEYLEIVDPETLKPLENIQNIGLLAIAAYIGSCRLIDNILLRNRKPIIAIDGPAGAGKSTVTKLVG
QSLGLLYLDTGAMYRAVTWMVLQSGVPVTDQAQVAELVSQCQISFNSPENNHVVINGQDVTVAIRSREVTNNVSIVAAQP
TVRYFMVKQQQQFGAKGGIVAEGRDIGSHVFPNAELKIFLTASLKERSRRRLVELKQKGQTNISLEEVEKEIICRDQKDT
NRKISPLRKSSDAVEISTDGLSIGEVTQKIVDIFKTTCYGKSSVNNII

Specific function: Displays a CMP kinase activity

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1786325, Length=293, Percent_Identity=37.542662116041, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1787139, Length=211, Percent_Identity=40.2843601895735, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322046, Length=287, Percent_Identity=39.0243902439024, Blast_Score=188, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANCY_TRIEI (Q110U9)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722448.1
- ProteinModelPortal:   Q110U9
- STRING:   Q110U9
- GeneID:   4245333
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2799
- NMPDR:   fig|203124.1.peg.4716
- eggNOG:   COG0414
- HOGENOM:   HBG428839
- OMA:   LGEKDWQ
- PhylomeDB:   Q110U9
- ProtClustDB:   PRK13477
- BioCyc:   TERY203124:TERY_2799-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01349
- InterPro:   IPR004821
- InterPro:   IPR003136
- InterPro:   IPR011994
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00017
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02224 Cytidylate_kin; PF02569 Pantoate_ligase

EC number: =6.3.2.1; =2.7.4.14

Molecular weight: Translated: 58428; Mature: 58428

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: ACT_SITE 41-41 BINDING 65-65 BINDING 65-65 BINDING 166-166 BINDING 189-189

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFTTIAGLNCYLNLLRNEQKKSPDTIGLVPTMGALHKGHLSLIKRAREENTITVVSIF
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
INPLQFAPREDFKEYPRQLEIDKEFCEKEGVDVIFAPTPETMGMKNALSTDAQDSTTTVV
ECCCCCCCCHHHHHCHHHCCCCHHHHHHCCCEEEEECCCCCCCCHHHHCCCCCCCCEEEE
SPSHMTSIMCGVSRPNFFQGVATIVTKLLNIVKPNNAYFGQKDAQQLAIIKQLVKDLSLP
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
VNIVYCPIIREASGLAISSRNQYLTPEQKEQASMLYASLCYGRKIFLENQDTPNILETVE
EEEEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
NAVKEKLASQPVLKLEYLEIVDPETLKPLENIQNIGLLAIAAYIGSCRLIDNILLRNRKP
HHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
IIAIDGPAGAGKSTVTKLVGQSLGLLYLDTGAMYRAVTWMVLQSGVPVTDQAQVAELVSQ
EEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
CQISFNSPENNHVVINGQDVTVAIRSREVTNNVSIVAAQPTVRYFMVKQQQQFGAKGGIV
HEEEECCCCCCEEEEECCEEEEEEECEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEE
AEGRDIGSHVFPNAELKIFLTASLKERSRRRLVELKQKGQTNISLEEVEKEIICRDQKDT
ECCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
NRKISPLRKSSDAVEISTDGLSIGEVTQKIVDIFKTTCYGKSSVNNII
CCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MRLFTTIAGLNCYLNLLRNEQKKSPDTIGLVPTMGALHKGHLSLIKRAREENTITVVSIF
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEE
INPLQFAPREDFKEYPRQLEIDKEFCEKEGVDVIFAPTPETMGMKNALSTDAQDSTTTVV
ECCCCCCCCHHHHHCHHHCCCCHHHHHHCCCEEEEECCCCCCCCHHHHCCCCCCCCEEEE
SPSHMTSIMCGVSRPNFFQGVATIVTKLLNIVKPNNAYFGQKDAQQLAIIKQLVKDLSLP
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
VNIVYCPIIREASGLAISSRNQYLTPEQKEQASMLYASLCYGRKIFLENQDTPNILETVE
EEEEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
NAVKEKLASQPVLKLEYLEIVDPETLKPLENIQNIGLLAIAAYIGSCRLIDNILLRNRKP
HHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
IIAIDGPAGAGKSTVTKLVGQSLGLLYLDTGAMYRAVTWMVLQSGVPVTDQAQVAELVSQ
EEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
CQISFNSPENNHVVINGQDVTVAIRSREVTNNVSIVAAQPTVRYFMVKQQQQFGAKGGIV
HEEEECCCCCCEEEEECCEEEEEEECEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEE
AEGRDIGSHVFPNAELKIFLTASLKERSRRRLVELKQKGQTNISLEEVEKEIICRDQKDT
ECCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCC
NRKISPLRKSSDAVEISTDGLSIGEVTQKIVDIFKTTCYGKSSVNNII
CCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA