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The map label for this gene is yugH [H]

Identifier: 113476317

GI number: 113476317

Start: 4209106

End: 4210269

Strand: Reverse

Name: yugH [H]

Synonym: Tery_2717

Alternate gene names: 113476317

Gene position: 4210269-4209106 (Counterclockwise)

Preceding gene: 113476318

Following gene: 113476311

Centisome position: 54.33

GC content: 32.13

Gene sequence:

>1164_bases
ATGAATTTTGCAACAAGAATGAATAGCTTAGGCGGAGATGCTGCAATTGAAGTTTTTACTAAAGCAAAACAATTAGAATC
TCAAGGTCGAAATATTATTCATTTAGAAATAGGTCAACCTGATTTTAAGACTCCTAAAAATATTCGCGAAGCTGCTTTCC
AAGCTATGAATGATGGCTATACAACTTATACTCCAGCAGCAGGTTTATTAAAGTTACGAGAAGTCATAGCAGAACATATT
TCTCAAACTAGAAATATATCAGTTAATTCTGATGAAGTAGTAGTAATGCCAGGAGCAAAACCAGTCATATTTTTTACTCT
TTTAGCATTAATAAATTCAGGAGATGAAGTGATTTATCCAAACCCTGGATTTCCTGTTTATGAATCAGTAATTAATTTAG
TGGGAGGGAAACCTATTCCATTACCTTTGTTAGAGGAATTAGATTTTCAATTTAGTATAGATAATCTAGTTAATTCTATT
TCAGAAAAAACAAAATTATTAATTATTAATTCTCCCCATAACCCTACTGGTAGTGTGTTAACTCCTGAGTATTTAGAAGC
CATAGCTAAATTAGCAGTTAAACATAATTTTTATGTTCTCTCTGATGAAATTTACTCCCACTTAAACTACGACTCAAAAT
TTACCAGTATCATCAGTTTTCCTAGTATGAAAGAACGTACAATTTTATTAGATGGGCACTCAAAAACTTATGCTATGACT
GGATGGCGTTTAGGTTATTCTATTTCTCCCAAAGCAATAGCAGAAAAGTTAGATAAATTGATGTTAAATTCTAATTCCTG
TGCTTGTTCATTTACTCAAATAGCTGGCATAGAAGCCATCAAAAATTCTCAGGAGTTTGTCAAAAAAATATTCGCAGAAT
TTAAACAAAGACGTGATGTTATTGTGGATGGTTTAAATTCTATTTCAGGTATTAATTGTCGAAAACCAGCAGGTGCTTTT
TATGCTTTTCCAAATGTGAAACAATTACCAATAAGTTCCAATAAATTGGCAGATTATTTATTAGCTGAAGCTGGAGTTGC
TTTATTACCCGGAACTGCTTATGGAAAATTTGGAGATGGATATTTAAGGTTGTCTTATGCTAATTCTATTGAAAATATTC
GCGAAGGTATTAGTCGGATAGAAACAGCGATCGCTAAACTATAG

Upstream 100 bases:

>100_bases
TTACTCGAATACTTTAGAGGAAAGTAATTTATATGCTGGTTGCTTTCCTTTCACCACGATCATCAAAAATTAAAGTGGGA
ATCTCCAGCAATTATTTAAG

Downstream 100 bases:

>100_bases
CTACCACCTTTTACTTATAAATTTCCCCTGAAACTTTTCCAATAAAATATCCGTAATTTCTGAAAAACCAGCAGATTATT
TATTAGCTCAACTTGGAGTT

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNFATRMNSLGGDAAIEVFTKAKQLESQGRNIIHLEIGQPDFKTPKNIREAAFQAMNDGYTTYTPAAGLLKLREVIAEHI
SQTRNISVNSDEVVVMPGAKPVIFFTLLALINSGDEVIYPNPGFPVYESVINLVGGKPIPLPLLEELDFQFSIDNLVNSI
SEKTKLLIINSPHNPTGSVLTPEYLEAIAKLAVKHNFYVLSDEIYSHLNYDSKFTSIISFPSMKERTILLDGHSKTYAMT
GWRLGYSISPKAIAEKLDKLMLNSNSCACSFTQIAGIEAIKNSQEFVKKIFAEFKQRRDVIVDGLNSISGINCRKPAGAF
YAFPNVKQLPISSNKLADYLLAEAGVALLPGTAYGKFGDGYLRLSYANSIENIREGISRIETAIAKL

Sequences:

>Translated_387_residues
MNFATRMNSLGGDAAIEVFTKAKQLESQGRNIIHLEIGQPDFKTPKNIREAAFQAMNDGYTTYTPAAGLLKLREVIAEHI
SQTRNISVNSDEVVVMPGAKPVIFFTLLALINSGDEVIYPNPGFPVYESVINLVGGKPIPLPLLEELDFQFSIDNLVNSI
SEKTKLLIINSPHNPTGSVLTPEYLEAIAKLAVKHNFYVLSDEIYSHLNYDSKFTSIISFPSMKERTILLDGHSKTYAMT
GWRLGYSISPKAIAEKLDKLMLNSNSCACSFTQIAGIEAIKNSQEFVKKIFAEFKQRRDVIVDGLNSISGINCRKPAGAF
YAFPNVKQLPISSNKLADYLLAEAGVALLPGTAYGKFGDGYLRLSYANSIENIREGISRIETAIAKL
>Mature_387_residues
MNFATRMNSLGGDAAIEVFTKAKQLESQGRNIIHLEIGQPDFKTPKNIREAAFQAMNDGYTTYTPAAGLLKLREVIAEHI
SQTRNISVNSDEVVVMPGAKPVIFFTLLALINSGDEVIYPNPGFPVYESVINLVGGKPIPLPLLEELDFQFSIDNLVNSI
SEKTKLLIINSPHNPTGSVLTPEYLEAIAKLAVKHNFYVLSDEIYSHLNYDSKFTSIISFPSMKERTILLDGHSKTYAMT
GWRLGYSISPKAIAEKLDKLMLNSNSCACSFTQIAGIEAIKNSQEFVKKIFAEFKQRRDVIVDGLNSISGINCRKPAGAF
YAFPNVKQLPISSNKLADYLLAEAGVALLPGTAYGKFGDGYLRLSYANSIENIREGISRIETAIAKL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=348, Percent_Identity=30.4597701149425, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI56713256, Length=348, Percent_Identity=30.4597701149425, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=25.3101736972705, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=25.3101736972705, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI4507369, Length=344, Percent_Identity=27.3255813953488, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI169881281, Length=287, Percent_Identity=26.1324041811847, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI19263340, Length=367, Percent_Identity=23.433242506812, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI215599424, Length=367, Percent_Identity=23.433242506812, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4885351, Length=342, Percent_Identity=24.8538011695906, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI187936925, Length=355, Percent_Identity=22.2535211267606, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI14211921, Length=355, Percent_Identity=22.2535211267606, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI149944424, Length=221, Percent_Identity=26.2443438914027, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1788722, Length=363, Percent_Identity=28.099173553719, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=26.6304347826087, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788627, Length=392, Percent_Identity=27.8061224489796, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787909, Length=365, Percent_Identity=24.1095890410959, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=227, Percent_Identity=35.2422907488987, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71994472, Length=227, Percent_Identity=35.2422907488987, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=30.0268096514745, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=387, Percent_Identity=26.3565891472868, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71981209, Length=398, Percent_Identity=27.3869346733668, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71981215, Length=188, Percent_Identity=29.2553191489362, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=27.7777777777778, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=358, Percent_Identity=24.3016759776536, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=360, Percent_Identity=23.8888888888889, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28573069, Length=377, Percent_Identity=25.4641909814324, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24646114, Length=377, Percent_Identity=25.4641909814324, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28573067, Length=377, Percent_Identity=25.4641909814324, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28573065, Length=377, Percent_Identity=25.4641909814324, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=23.5924932975871, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI45551451, Length=379, Percent_Identity=29.287598944591, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641770, Length=371, Percent_Identity=29.1105121293801, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641760, Length=371, Percent_Identity=29.1105121293801, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641768, Length=371, Percent_Identity=29.1105121293801, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641766, Length=371, Percent_Identity=29.1105121293801, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24641764, Length=371, Percent_Identity=29.1105121293801, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42611; Mature: 42611

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFATRMNSLGGDAAIEVFTKAKQLESQGRNIIHLEIGQPDFKTPKNIREAAFQAMNDGY
CCHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCC
TTYTPAAGLLKLREVIAEHISQTRNISVNSDEVVVMPGAKPVIFFTLLALINSGDEVIYP
CEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEC
NPGFPVYESVINLVGGKPIPLPLLEELDFQFSIDNLVNSISEKTKLLIINSPHNPTGSVL
CCCCHHHHHHHHHHCCCCCCCHHHHHCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCCCC
TPEYLEAIAKLAVKHNFYVLSDEIYSHLNYDSKFTSIISFPSMKERTILLDGHSKTYAMT
CHHHHHHHHHHHHHCCEEEEEHHHHHHCCCCHHHHHHHCCCCCCCCEEEEECCCCEEEEE
GWRLGYSISPKAIAEKLDKLMLNSNSCACSFTQIAGIEAIKNSQEFVKKIFAEFKQRRDV
CEEECCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IVDGLNSISGINCRKPAGAFYAFPNVKQLPISSNKLADYLLAEAGVALLPGTAYGKFGDG
HHHCHHHCCCCCCCCCCCCEEECCCCEECCCCCHHHHHHHHHHCCCEEECCCCCCCCCCC
YLRLSYANSIENIREGISRIETAIAKL
EEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFATRMNSLGGDAAIEVFTKAKQLESQGRNIIHLEIGQPDFKTPKNIREAAFQAMNDGY
CCHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCC
TTYTPAAGLLKLREVIAEHISQTRNISVNSDEVVVMPGAKPVIFFTLLALINSGDEVIYP
CEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEC
NPGFPVYESVINLVGGKPIPLPLLEELDFQFSIDNLVNSISEKTKLLIINSPHNPTGSVL
CCCCHHHHHHHHHHCCCCCCCHHHHHCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCCCC
TPEYLEAIAKLAVKHNFYVLSDEIYSHLNYDSKFTSIISFPSMKERTILLDGHSKTYAMT
CHHHHHHHHHHHHHCCEEEEEHHHHHHCCCCHHHHHHHCCCCCCCCEEEEECCCCEEEEE
GWRLGYSISPKAIAEKLDKLMLNSNSCACSFTQIAGIEAIKNSQEFVKKIFAEFKQRRDV
CEEECCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IVDGLNSISGINCRKPAGAFYAFPNVKQLPISSNKLADYLLAEAGVALLPGTAYGKFGDG
HHHCHHHCCCCCCCCCCCCEEECCCCEECCCCCHHHHHHHHHHCCCEEECCCCCCCCCCC
YLRLSYANSIENIREGISRIETAIAKL
EEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]