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The map label for this gene is nadA

Identifier: 113476070

GI number: 113476070

Start: 3769757

End: 3770728

Strand: Reverse

Name: nadA

Synonym: Tery_2446

Alternate gene names: 113476070

Gene position: 3770728-3769757 (Counterclockwise)

Preceding gene: 113476080

Following gene: 113476067

Centisome position: 48.65

GC content: 37.65

Gene sequence:

>972_bases
ATGTTTGCAACTCAAACTCGAATCAACCAAAATTTTAATAGCATACCAGATGATTTGTTTGAAGCGATCGCCGACCTAAA
GAAAGAATTAAATGCTGTTATTCTAGCTCACTATTACCAAGAACCAGATATTCAAGATATTGCCGACTATATTGGTGACT
CTCTTGGCCTTTCTCAAAAAGCTGCTGAAACTGATGCAGATGTAATAGTTTTTGCGGGAGTTCATTTTATGGCAGAAACT
GCGAAAATTCTTAACCCAAATAAACTGGTACTGCTACCAGATCTAGATGCAGGTTGCTCCCTCGCCGATAGTTGTCCACC
AGAAGAATTTGGCAAATTTAAGGCGGCTCATCCTGATGCCATAGTAGTTTCTTATATTAATTGTACTGCTGCTATTAAGG
CAATGAGTGATATTATTTGCACCAGTTCCAACTCTGTCAAAATAGTTAAACAAATACCAACAGACCAACCGATAATTTTT
GCCCCAGATAAGAACCTCGGTCGCTATGTCATGGAACAAACTGGACGAGATTTGATTTTGTGGTCAGGCAGTTGTATTGT
TCACGAGACATTCTCTGAGAAAAAGATTGTGCAATTAAAAATAGAACATCCTGAAGCTGAGATTATTGCTCATCCAGAAT
GTGAACCAAATTTATTGCGTCATGCCAATTATATTGGTTCGACCACTGCTTTATTAAAATATTGCCAAGAAAGCCAAGAG
CAAGAATTTATTGTGGCAACTGAACCGGGAATTATTCACCAAATGCAAAAGAGAGAACCCAAGAAAAACTTTATTCCCGC
ACCCGCAATGAATAATTGTGCTTGTAACGAATGCCCCCACATGAGGCTGAATAATTTAGAAAAGCTTTATTTAGCAATGA
AAAATAAGACGCCAGAAATTATGATTCCTGAAGAAACACGAGTAGCAGCATTAAAACCTATTCAAAAGATGTTGGAACTT
TCATTCACATAA

Upstream 100 bases:

>100_bases
TGTATCAAACCCTAATTATAGTATAATTCATCAAACTATCTAAAGTAACTATAATTGGCCACTTAGTTACAAATAAATTA
CAGAGAAACTTAATTTAATA

Downstream 100 bases:

>100_bases
TAAAAATGCTCTTCTCTGTCTCAAGAGAATTCTAGCAAATTTTTCCCAATGCCCTAATAACTTTTATTTGTGATTTAGTC
GATTATTTTAGACAAAAAGT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MFATQTRINQNFNSIPDDLFEAIADLKKELNAVILAHYYQEPDIQDIADYIGDSLGLSQKAAETDADVIVFAGVHFMAET
AKILNPNKLVLLPDLDAGCSLADSCPPEEFGKFKAAHPDAIVVSYINCTAAIKAMSDIICTSSNSVKIVKQIPTDQPIIF
APDKNLGRYVMEQTGRDLILWSGSCIVHETFSEKKIVQLKIEHPEAEIIAHPECEPNLLRHANYIGSTTALLKYCQESQE
QEFIVATEPGIIHQMQKREPKKNFIPAPAMNNCACNECPHMRLNNLEKLYLAMKNKTPEIMIPEETRVAALKPIQKMLEL
SFT

Sequences:

>Translated_323_residues
MFATQTRINQNFNSIPDDLFEAIADLKKELNAVILAHYYQEPDIQDIADYIGDSLGLSQKAAETDADVIVFAGVHFMAET
AKILNPNKLVLLPDLDAGCSLADSCPPEEFGKFKAAHPDAIVVSYINCTAAIKAMSDIICTSSNSVKIVKQIPTDQPIIF
APDKNLGRYVMEQTGRDLILWSGSCIVHETFSEKKIVQLKIEHPEAEIIAHPECEPNLLRHANYIGSTTALLKYCQESQE
QEFIVATEPGIIHQMQKREPKKNFIPAPAMNNCACNECPHMRLNNLEKLYLAMKNKTPEIMIPEETRVAALKPIQKMLEL
SFT
>Mature_323_residues
MFATQTRINQNFNSIPDDLFEAIADLKKELNAVILAHYYQEPDIQDIADYIGDSLGLSQKAAETDADVIVFAGVHFMAET
AKILNPNKLVLLPDLDAGCSLADSCPPEEFGKFKAAHPDAIVVSYINCTAAIKAMSDIICTSSNSVKIVKQIPTDQPIIF
APDKNLGRYVMEQTGRDLILWSGSCIVHETFSEKKIVQLKIEHPEAEIIAHPECEPNLLRHANYIGSTTALLKYCQESQE
QEFIVATEPGIIHQMQKREPKKNFIPAPAMNNCACNECPHMRLNNLEKLYLAMKNKTPEIMIPEETRVAALKPIQKMLEL
SFT

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=314, Percent_Identity=41.4012738853503, Blast_Score=246, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_TRIEI (Q112B6)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722131.1
- ProteinModelPortal:   Q112B6
- SMR:   Q112B6
- STRING:   Q112B6
- GeneID:   4244630
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2446
- NMPDR:   fig|203124.1.peg.1282
- eggNOG:   COG0379
- HOGENOM:   HBG291157
- OMA:   IAHPECE
- PhylomeDB:   Q112B6
- ProtClustDB:   PRK09375
- BioCyc:   TERY203124:TERY_2446-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00568
- InterPro:   IPR003473
- InterPro:   IPR023066
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 36043; Mature: 36043

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: BINDING 37-37 BINDING 54-54 BINDING 125-125 BINDING 142-142 BINDING 211-211 BINDING 228-228

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFATQTRINQNFNSIPDDLFEAIADLKKELNAVILAHYYQEPDIQDIADYIGDSLGLSQK
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCHHCCCCHH
AAETDADVIVFAGVHFMAETAKILNPNKLVLLPDLDAGCSLADSCPPEEFGKFKAAHPDA
HCCCCCCEEEEECHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCE
IVVSYINCTAAIKAMSDIICTSSNSVKIVKQIPTDQPIIFAPDKNLGRYVMEQTGRDLIL
EEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCHHHHHHHHCCCEEEE
WSGSCIVHETFSEKKIVQLKIEHPEAEIIAHPECEPNLLRHANYIGSTTALLKYCQESQE
ECCCEEEEECCCCCEEEEEEEECCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHCCC
QEFIVATEPGIIHQMQKREPKKNFIPAPAMNNCACNECPHMRLNNLEKLYLAMKNKTPEI
CCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCE
MIPEETRVAALKPIQKMLELSFT
ECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFATQTRINQNFNSIPDDLFEAIADLKKELNAVILAHYYQEPDIQDIADYIGDSLGLSQK
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHCHHCCCCHH
AAETDADVIVFAGVHFMAETAKILNPNKLVLLPDLDAGCSLADSCPPEEFGKFKAAHPDA
HCCCCCCEEEEECHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCE
IVVSYINCTAAIKAMSDIICTSSNSVKIVKQIPTDQPIIFAPDKNLGRYVMEQTGRDLIL
EEEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCHHHHHHHHCCCEEEE
WSGSCIVHETFSEKKIVQLKIEHPEAEIIAHPECEPNLLRHANYIGSTTALLKYCQESQE
ECCCEEEEECCCCCEEEEEEEECCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHCCC
QEFIVATEPGIIHQMQKREPKKNFIPAPAMNNCACNECPHMRLNNLEKLYLAMKNKTPEI
CCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCE
MIPEETRVAALKPIQKMLELSFT
ECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA