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The map label for this gene is sigC [H]

Identifier: 113475621

GI number: 113475621

Start: 3031977

End: 3033209

Strand: Reverse

Name: sigC [H]

Synonym: Tery_1956

Alternate gene names: 113475621

Gene position: 3033209-3031977 (Counterclockwise)

Preceding gene: 113475622

Following gene: 113475618

Centisome position: 39.14

GC content: 36.58

Gene sequence:

>1233_bases
ATGATCACTACCTCAGAAATTTATCCTTACACTGAAGACACACTGCAATCTAATAACTTGCAGAATGAGTGTTCTGAACA
TCTAGGTCAAACTATCAATGAATTAACAATAGAGGATAAAAAAGTAGATAGTTCTCAAATAAACACTAACTATAGTGGCA
GAGATTCAGTCCGTTCATACCTCCAAGAAATTGGGCGAGTTGATTTGCTTCAAAGAGATCAAGAAGTTTCTACAGCTCAA
AAAGTTCAACGTTATGTACATTTATTGGAGTTACGCAACAAAGCCGCTGAACAAGAACAAGAAATTCAGCGTTATGTTGA
GATGATCAAGATTCGTGATCGTCTGGCAGCTCGTTTAGGACATAAACCATCATTTGAGCGGTGGCTAAAGGCAGGAAATT
TATCTATGGCAGAACTGAAAGAGATCATTGCTGTAGGAAAACTTCGCTGGGCAAAGTTAACAGGTTTAAATGTAAAGGAA
CTTGAGCAAATTCAAACCGAAGGCATTGAAGCGAGACATCAGATGATAAGTACTAACTTGCGCTTAGTAGTCTCAATAGC
AAAAAAGTATCAAAATCGTGGTGTAGAACTTTTAGATTTAATCCAAGAAGGTACTTTGGGTTTAGAAAGAGCTGTTGAAA
AATTTGATCCACAACGGGGATATAGATTTAGCACTTATGCTTACTGGTGGATTCGTCAAGGAATTACAAGAGCAATTGCT
ACTCAAAGTCGAACAATTCGTTTACCTATCCATGTTAGCGAAAAATTAAATAAAATCAAAAAAGTACAACAAAAAATTTT
TCAAGAAAAAGGATATACGGCTAAAGTTGAAGAAATTGCCCGAGAATTAAAAATTACAGCTGCCCAAGTTCGAGAAGTGT
TAGTAAAAATTCCACACTCGGTTTCCTTAGAAACTAAGGTCGGTAGGGATAGAGATACTGAATTAGGGGAACTTCTGGAA
ACTAAAGATGCTTCTCCAGAAGAAATGTTAATACGAGAGTCTCTGGTACAAGCTTTAAAAGAGTTACTATTAGATTTAAC
TCAACGAGAAAGGTATGTAATTACTATGCGTTATGGCTTAGAAGATGGTCGTGCCTGCTCCTTATCAGAAATTGCGTCTG
CATTGAAACTCTCTCGGGAACGAGTACGTCAAATTGAAGTCAAGGCTCTACATAAGTTGCGTCAACCAAAGTTTCGTAAT
CAAATACAGGATTATTTAGAATCTTTGAATTAA

Upstream 100 bases:

>100_bases
AATCAGAAAACATAAGTATAAAAAACGCCAACTTTTTATAAATTAGGCATTTTATTAATAGACCATAACTAAGTGTAGCC
TCTTTTCAGGAGTAAACGAG

Downstream 100 bases:

>100_bases
AAAAAATTGAGATCACTCAAATAATATAATTAGGAGTTATTCAAGTACCCTATATGTTGTTTACTCATTATTAGAGATAT
TTATAAAAAAGTATAAAATT

Product: RNA polymerase, sigma 28 subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MITTSEIYPYTEDTLQSNNLQNECSEHLGQTINELTIEDKKVDSSQINTNYSGRDSVRSYLQEIGRVDLLQRDQEVSTAQ
KVQRYVHLLELRNKAAEQEQEIQRYVEMIKIRDRLAARLGHKPSFERWLKAGNLSMAELKEIIAVGKLRWAKLTGLNVKE
LEQIQTEGIEARHQMISTNLRLVVSIAKKYQNRGVELLDLIQEGTLGLERAVEKFDPQRGYRFSTYAYWWIRQGITRAIA
TQSRTIRLPIHVSEKLNKIKKVQQKIFQEKGYTAKVEEIARELKITAAQVREVLVKIPHSVSLETKVGRDRDTELGELLE
TKDASPEEMLIRESLVQALKELLLDLTQRERYVITMRYGLEDGRACSLSEIASALKLSRERVRQIEVKALHKLRQPKFRN
QIQDYLESLN

Sequences:

>Translated_410_residues
MITTSEIYPYTEDTLQSNNLQNECSEHLGQTINELTIEDKKVDSSQINTNYSGRDSVRSYLQEIGRVDLLQRDQEVSTAQ
KVQRYVHLLELRNKAAEQEQEIQRYVEMIKIRDRLAARLGHKPSFERWLKAGNLSMAELKEIIAVGKLRWAKLTGLNVKE
LEQIQTEGIEARHQMISTNLRLVVSIAKKYQNRGVELLDLIQEGTLGLERAVEKFDPQRGYRFSTYAYWWIRQGITRAIA
TQSRTIRLPIHVSEKLNKIKKVQQKIFQEKGYTAKVEEIARELKITAAQVREVLVKIPHSVSLETKVGRDRDTELGELLE
TKDASPEEMLIRESLVQALKELLLDLTQRERYVITMRYGLEDGRACSLSEIASALKLSRERVRQIEVKALHKLRQPKFRN
QIQDYLESLN
>Mature_410_residues
MITTSEIYPYTEDTLQSNNLQNECSEHLGQTINELTIEDKKVDSSQINTNYSGRDSVRSYLQEIGRVDLLQRDQEVSTAQ
KVQRYVHLLELRNKAAEQEQEIQRYVEMIKIRDRLAARLGHKPSFERWLKAGNLSMAELKEIIAVGKLRWAKLTGLNVKE
LEQIQTEGIEARHQMISTNLRLVVSIAKKYQNRGVELLDLIQEGTLGLERAVEKFDPQRGYRFSTYAYWWIRQGITRAIA
TQSRTIRLPIHVSEKLNKIKKVQQKIFQEKGYTAKVEEIARELKITAAQVREVLVKIPHSVSLETKVGRDRDTELGELLE
TKDASPEEMLIRESLVQALKELLLDLTQRERYVITMRYGLEDGRACSLSEIASALKLSRERVRQIEVKALHKLRQPKFRN
QIQDYLESLN

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=263, Percent_Identity=42.2053231939163, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789098, Length=228, Percent_Identity=43.421052631579, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789871, Length=259, Percent_Identity=29.3436293436293, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788231, Length=234, Percent_Identity=28.6324786324786, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR017848
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 47571; Mature: 47571

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00715 SIGMA70_1 ; PS00716 SIGMA70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385387; 11759840 [H]