Click here to switch to the map view.

The map label for this gene is hrcA [H]

Identifier: 113474557

GI number: 113474557

Start: 1150922

End: 1152034

Strand: Reverse

Name: hrcA [H]

Synonym: Tery_0712

Alternate gene names: 113474557

Gene position: 1152034-1150922 (Counterclockwise)

Preceding gene: 113474558

Following gene: 113474555

Centisome position: 14.86

GC content: 37.92

Gene sequence:

>1113_bases
ATGTCATTACAAGTTAAGCTTAATAATCGTCATCAACATATTCTCTGGGCAACAGTTCGCCACTATATTGCGACAGCAGA
GCCAGTTGGCTCAAAATCCCTTGTAGAAGAGTATAATCTCAGTGTTAGTCCAGCGACAATTCGCAATGGGATGAGCTTTT
TAGAGAAAAGCGGACTATTATATCAACCTCATACTTCGGCTGGAAGAATTCCATCGGACTCAGGTTACCGAATATATGTT
GACCAATTAATTAGACCTTCAGAAAATCTAGCTTTTGAAATTGAAGAGCTTTTACAAAAGCAACTAAATTGGCCAGAAGG
TCGCCTAGAAGTTGTACTTCAAGGAGCCGCTCAAATTTTAGCTAGCCTCAGTGGTTATATTACTCTGGTGACAATGCCCC
AAACTTCGACGGCTAAGCTACGACATCTACAATTGGTACAAGTGGAAGCAGAGAAAATCATGCTAATTGTAGTGACAAAT
ACCTATGAAACTCAATCACTGATTATGGACTTAAAGACAATAAATCAGATAAATGATCGCAAAAATTTACAGGGTAATTC
TGCCGTCCCCAATTTAGAAGATATTGATCGAGAATTACAAATATTATCAAATTTTTTGAATAGTCAGCTAAAAGGACGAG
TAATAGGGGAATTATCTTTATTGGACTGGAGTGAGCTAGACTGGGAGTTTGAGAAATACGCTAAATTGATCAAAAATCTG
TTGGAAAATTTAACTCTGCGTTGTGGAACGCCTAAATATACTAGAATATTAATTAGCGGTATAGCAGAAGCACTACGTTT
GCCAGAATTCTCCCAACTTGAACAGGTCCAAACTATTATTCAACTACTTGAAGAAAAACAAGATAAATTGTGGCCTTTGA
TATTTGGAAGTACTACTAAAAAAACAGATCGACAGGTGAGAGTTACAATTGGTTCAGAAAATCCTTTGGAACCTATTCAA
GGTTGTGCCTTAGTTTCTGCAACTTATGGAAATGGGACAGTTCCTCTAGGAAGTGTGGGAGTTTTAGGACCGACTAGGAT
GGTCTATGAGAATGCGATCGTTCTAGTTAAATCTACGGCGGATTTTCTATCGGAAGCAATGGGAAGTTATTAA

Upstream 100 bases:

>100_bases
TAAATTTTATTAAGAAAAATAAATTTAACCTTATCATAAACATAAAATTATTTTTTCTATTATTGTTTGGTAGCTTCCGG
AATATACTCACCCTACATCC

Downstream 100 bases:

>100_bases
GTAGCTGAAAATAATTAATTTTATATAAAGTTTTCATTTGAGATGAGTAAATAAGTAGGGAATGGTTTAGTAAAATCCAA
TTGAGGTTATCTGGTTATAC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSLQVKLNNRHQHILWATVRHYIATAEPVGSKSLVEEYNLSVSPATIRNGMSFLEKSGLLYQPHTSAGRIPSDSGYRIYV
DQLIRPSENLAFEIEELLQKQLNWPEGRLEVVLQGAAQILASLSGYITLVTMPQTSTAKLRHLQLVQVEAEKIMLIVVTN
TYETQSLIMDLKTINQINDRKNLQGNSAVPNLEDIDRELQILSNFLNSQLKGRVIGELSLLDWSELDWEFEKYAKLIKNL
LENLTLRCGTPKYTRILISGIAEALRLPEFSQLEQVQTIIQLLEEKQDKLWPLIFGSTTKKTDRQVRVTIGSENPLEPIQ
GCALVSATYGNGTVPLGSVGVLGPTRMVYENAIVLVKSTADFLSEAMGSY

Sequences:

>Translated_370_residues
MSLQVKLNNRHQHILWATVRHYIATAEPVGSKSLVEEYNLSVSPATIRNGMSFLEKSGLLYQPHTSAGRIPSDSGYRIYV
DQLIRPSENLAFEIEELLQKQLNWPEGRLEVVLQGAAQILASLSGYITLVTMPQTSTAKLRHLQLVQVEAEKIMLIVVTN
TYETQSLIMDLKTINQINDRKNLQGNSAVPNLEDIDRELQILSNFLNSQLKGRVIGELSLLDWSELDWEFEKYAKLIKNL
LENLTLRCGTPKYTRILISGIAEALRLPEFSQLEQVQTIIQLLEEKQDKLWPLIFGSTTKKTDRQVRVTIGSENPLEPIQ
GCALVSATYGNGTVPLGSVGVLGPTRMVYENAIVLVKSTADFLSEAMGSY
>Mature_369_residues
SLQVKLNNRHQHILWATVRHYIATAEPVGSKSLVEEYNLSVSPATIRNGMSFLEKSGLLYQPHTSAGRIPSDSGYRIYVD
QLIRPSENLAFEIEELLQKQLNWPEGRLEVVLQGAAQILASLSGYITLVTMPQTSTAKLRHLQLVQVEAEKIMLIVVTNT
YETQSLIMDLKTINQINDRKNLQGNSAVPNLEDIDRELQILSNFLNSQLKGRVIGELSLLDWSELDWEFEKYAKLIKNLL
ENLTLRCGTPKYTRILISGIAEALRLPEFSQLEQVQTIIQLLEEKQDKLWPLIFGSTTKKTDRQVRVTIGSENPLEPIQG
CALVSATYGNGTVPLGSVGVLGPTRMVYENAIVLVKSTADFLSEAMGSY

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 41452; Mature: 41321

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQVKLNNRHQHILWATVRHYIATAEPVGSKSLVEEYNLSVSPATIRNGMSFLEKSGLL
CEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCE
YQPHTSAGRIPSDSGYRIYVDQLIRPSENLAFEIEELLQKQLNWPEGRLEVVLQGAAQIL
ECCCCCCCCCCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ASLSGYITLVTMPQTSTAKLRHLQLVQVEAEKIMLIVVTNTYETQSLIMDLKTINQINDR
HHCCCCEEEEECCCCCHHHHHHHEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
KNLQGNSAVPNLEDIDRELQILSNFLNSQLKGRVIGELSLLDWSELDWEFEKYAKLIKNL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHCCCCHHHHHHHHHHH
LENLTLRCGTPKYTRILISGIAEALRLPEFSQLEQVQTIIQLLEEKQDKLWPLIFGSTTK
HHHCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
KTDRQVRVTIGSENPLEPIQGCALVSATYGNGTVPLGSVGVLGPTRMVYENAIVLVKSTA
CCCCEEEEEECCCCCCCHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCEEEEEECHH
DFLSEAMGSY
HHHHHHHCCC
>Mature Secondary Structure 
SLQVKLNNRHQHILWATVRHYIATAEPVGSKSLVEEYNLSVSPATIRNGMSFLEKSGLL
EEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCE
YQPHTSAGRIPSDSGYRIYVDQLIRPSENLAFEIEELLQKQLNWPEGRLEVVLQGAAQIL
ECCCCCCCCCCCCCCCEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ASLSGYITLVTMPQTSTAKLRHLQLVQVEAEKIMLIVVTNTYETQSLIMDLKTINQINDR
HHCCCCEEEEECCCCCHHHHHHHEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHH
KNLQGNSAVPNLEDIDRELQILSNFLNSQLKGRVIGELSLLDWSELDWEFEKYAKLIKNL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHCCCCHHHHHHHHHHH
LENLTLRCGTPKYTRILISGIAEALRLPEFSQLEQVQTIIQLLEEKQDKLWPLIFGSTTK
HHHCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
KTDRQVRVTIGSENPLEPIQGCALVSATYGNGTVPLGSVGVLGPTRMVYENAIVLVKSTA
CCCCEEEEEECCCCCCCHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHCCEEEEEECHH
DFLSEAMGSY
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA