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The map label for this gene is ppiA [C]

Identifier: 113474378

GI number: 113474378

Start: 814085

End: 814846

Strand: Reverse

Name: ppiA [C]

Synonym: Tery_0511

Alternate gene names: 113474378

Gene position: 814846-814085 (Counterclockwise)

Preceding gene: 113474379

Following gene: 113474377

Centisome position: 10.51

GC content: 38.45

Gene sequence:

>762_bases
ATGCAAAGAAAAATTAGTCAGTGGTTATTGCCACTGTTCCTAATTGTAACTTTATTAGTAACAGGATGTAGTGGTACTTC
AGTTTCTAATGCCGAAGTTTCCACCTCAAATTCATCAAGTCAAACACAACTCGCCACTAAATATAATTATTTACCTAAAC
TCAACGGTAAGGCAAAAGTGGAAATGATTGTTAATTCCTCTGTTATAACAATAGAAGTAGATGGTGATAACGCACCTATT
ACAGCAGGTAATTTTGTGGACCTAGTTCAACAAGGGGTTTATGATGGGTTAGCATTTCATCGGGTAGTGCGTGAACCTCA
ACCTTTTGTGGTTCAGGGTGGGGATCCTCAAAGTAAAGACCTCAATGTTCCCCTAAATAATTTAGGTACAGGAGGTTTTA
TCGATCCAAAAACTTCAAGGGAGCGTTATATCCCTCTAGAAATTAAACCCACAGAAGCTAAAGAACCAGTTTACAGCAAA
ACCTTTGAAGTAGCTGGTATTCAACAGCAGCCTATTTTATATCATAAAAGGGGTGCTGTGGCCATGGCTCGCTCTCAGCC
TCCTGACTCTGCTTCTTCCCAATTTTATTTTGCTTTAACTGACCTTCCTTTCCTTGATGGTAGCTATGCAGTATTTGGTA
ATGTGACACAAGGGATGAAAGAAGTTGTTGATCAAATTCAAGCTGGTGATCGTATTGAGTCAGCAAAAGTAGTTGAGGGT
ATTGAAAATTTAACCATAAAAACTAATCGTAACCAATCATAG

Upstream 100 bases:

>100_bases
CAAACCTAAGTTTAGTAAAACGGTAATAGTTTTTAACTCACAATATTCGACCAGCTAGTAGGTAGGTCTCAAAACAATTA
AGATTAAATTTTTAGTGAAA

Downstream 100 bases:

>100_bases
CTTAACTATGAAAGTTTTAGTTACGGGTATTGGGCTAACTTCTAGTTTGGGAAACCTCTTTCAAAGTTGGGAAAAACTAC
TTGATGGTAAGTCTGCTATT

Product: cyclophilin type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase sll0227; Rotamase sll0227 [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MQRKISQWLLPLFLIVTLLVTGCSGTSVSNAEVSTSNSSSQTQLATKYNYLPKLNGKAKVEMIVNSSVITIEVDGDNAPI
TAGNFVDLVQQGVYDGLAFHRVVREPQPFVVQGGDPQSKDLNVPLNNLGTGGFIDPKTSRERYIPLEIKPTEAKEPVYSK
TFEVAGIQQQPILYHKRGAVAMARSQPPDSASSQFYFALTDLPFLDGSYAVFGNVTQGMKEVVDQIQAGDRIESAKVVEG
IENLTIKTNRNQS

Sequences:

>Translated_253_residues
MQRKISQWLLPLFLIVTLLVTGCSGTSVSNAEVSTSNSSSQTQLATKYNYLPKLNGKAKVEMIVNSSVITIEVDGDNAPI
TAGNFVDLVQQGVYDGLAFHRVVREPQPFVVQGGDPQSKDLNVPLNNLGTGGFIDPKTSRERYIPLEIKPTEAKEPVYSK
TFEVAGIQQQPILYHKRGAVAMARSQPPDSASSQFYFALTDLPFLDGSYAVFGNVTQGMKEVVDQIQAGDRIESAKVVEG
IENLTIKTNRNQS
>Mature_253_residues
MQRKISQWLLPLFLIVTLLVTGCSGTSVSNAEVSTSNSSSQTQLATKYNYLPKLNGKAKVEMIVNSSVITIEVDGDNAPI
TAGNFVDLVQQGVYDGLAFHRVVREPQPFVVQGGDPQSKDLNVPLNNLGTGGFIDPKTSRERYIPLEIKPTEAKEPVYSK
TFEVAGIQQQPILYHKRGAVAMARSQPPDSASSQFYFALTDLPFLDGSYAVFGNVTQGMKEVVDQIQAGDRIESAKVVEG
IENLTIKTNRNQS

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 27611; Mature: 27611

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRKISQWLLPLFLIVTLLVTGCSGTSVSNAEVSTSNSSSQTQLATKYNYLPKLNGKAKV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCEEE
EMIVNSSVITIEVDGDNAPITAGNFVDLVQQGVYDGLAFHRVVREPQPFVVQGGDPQSKD
EEEECCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
LNVPLNNLGTGGFIDPKTSRERYIPLEIKPTEAKEPVYSKTFEVAGIQQQPILYHKRGAV
CCCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHCEEEECCCCCCCEEEECCCCE
AMARSQPPDSASSQFYFALTDLPFLDGSYAVFGNVTQGMKEVVDQIQAGDRIESAKVVEG
EEECCCCCCCCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHH
IENLTIKTNRNQS
HHHEEEEECCCCC
>Mature Secondary Structure
MQRKISQWLLPLFLIVTLLVTGCSGTSVSNAEVSTSNSSSQTQLATKYNYLPKLNGKAKV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCEEE
EMIVNSSVITIEVDGDNAPITAGNFVDLVQQGVYDGLAFHRVVREPQPFVVQGGDPQSKD
EEEECCEEEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
LNVPLNNLGTGGFIDPKTSRERYIPLEIKPTEAKEPVYSKTFEVAGIQQQPILYHKRGAV
CCCCHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHCEEEECCCCCCCEEEECCCCE
AMARSQPPDSASSQFYFALTDLPFLDGSYAVFGNVTQGMKEVVDQIQAGDRIESAKVVEG
EEECCCCCCCCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHH
IENLTIKTNRNQS
HHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]