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The map label for this gene is fabF [H]

Identifier: 113474377

GI number: 113474377

Start: 812932

End: 814077

Strand: Reverse

Name: fabF [H]

Synonym: Tery_0510

Alternate gene names: 113474377

Gene position: 814077-812932 (Counterclockwise)

Preceding gene: 113474378

Following gene: 113474371

Centisome position: 10.5

GC content: 40.14

Gene sequence:

>1146_bases
ATGAAAGTTTTAGTTACGGGTATTGGGCTAACTTCTAGTTTGGGAAACCTCTTTCAAAGTTGGGAAAAACTACTTGATGG
TAAGTCTGCTATTCGGTTAGTTAAACCTTTTGCAGAATTACCTCCCCTACCTTTGGGTTTAATTAATTCTCAGCCTGTAG
ATTTAACTAACTTAATTAAGCAAACTGTGGAAACTGCTGTCAAGTCTTCCGGTCTGAAGCTTCCATTACCTGAATGTGGT
GTCGTTATTGGTTCGAGCCGTGCCTATCAAAGAATGCTAGAAAATTTAGCCAAAAAGCAGTTTGTTGATGATGGTCAGGA
TCATAGTCAAAAAGATTATGGATCATTTATTAATTTTTGGCCTCATCAGCCTGCTATTTTAACTGCGAGTCAGATAGGTA
CAAAGGGCACTGTTTTGTCTCCAATGGCAGCCTGTGCTACAGGAATATTAGCGATCGCTCGTGGTTTTGAATTAATTCAG
ACTGGCCAATGTCAACAGGTTATAGCGGGTGCTGTTGAATCTCCTATTACACCTCTTACTATAGCAGGATTTAGAAAAAT
GGGAGCCTTAGCTCAAATAGGTGCCTATCCTTTTGACCGAGCTCGAGAAGGATTTGTTTTGGGGGAAGGAGCAGCTATTT
TGCTACTAGAGTCTGCTAATTTTGCTAAGAAAAGAAGTGCTAAAGTTTATGGTCAAATTCGCAGTTTTGGCTTGACAAAT
GATGGAATTCATAGTGTAATTCCTGATTTGAGTGGTAAAAGTGCAATGTTAGCGATCGCTCGATCTTTAGCAAGAAGTGG
TTTAGCTCCTGAAGAAATTGACTATGTTCATGCTCATGGAACGGCAACTAAATTAAATGATCGCCATGAAGCTAATTTAA
TTCAGCAAATTTTTCCTCACAAAGTAGCAGTTAGTTCGACAAAGGGGGCGACTGGTCATACTTTGGGAGCATCTGGAGCA
TTAGGTGCTGCATTTTGTTTGATGGCGGTCAAACATCAGGTTTTACCTCCCTGTGTTGGTTTGAATTCACCAGAATTTGA
CCTAGACTTGGTTAGGTATGCTCGTCAGTCTCAGGTGAAAAATGTTTTATGTTTGAGTTTTGGGTTTGGGGGTCAAAATG
CCGCTTTAGTTTTAAGTAAGGTGTAG

Upstream 100 bases:

>100_bases
GATCAAATTCAAGCTGGTGATCGTATTGAGTCAGCAAAAGTAGTTGAGGGTATTGAAAATTTAACCATAAAAACTAATCG
TAACCAATCATAGCTTAACT

Downstream 100 bases:

>100_bases
CGATCGCTAAACTAACACAGGTGTAATAACCTTTTTGATAATTATTAACCATGAAGCGTGTGAATTTTTCTAAATTTTTT
ACAAACGTTGCATGGAAAGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKVLVTGIGLTSSLGNLFQSWEKLLDGKSAIRLVKPFAELPPLPLGLINSQPVDLTNLIKQTVETAVKSSGLKLPLPECG
VVIGSSRAYQRMLENLAKKQFVDDGQDHSQKDYGSFINFWPHQPAILTASQIGTKGTVLSPMAACATGILAIARGFELIQ
TGQCQQVIAGAVESPITPLTIAGFRKMGALAQIGAYPFDRAREGFVLGEGAAILLLESANFAKKRSAKVYGQIRSFGLTN
DGIHSVIPDLSGKSAMLAIARSLARSGLAPEEIDYVHAHGTATKLNDRHEANLIQQIFPHKVAVSSTKGATGHTLGASGA
LGAAFCLMAVKHQVLPPCVGLNSPEFDLDLVRYARQSQVKNVLCLSFGFGGQNAALVLSKV

Sequences:

>Translated_381_residues
MKVLVTGIGLTSSLGNLFQSWEKLLDGKSAIRLVKPFAELPPLPLGLINSQPVDLTNLIKQTVETAVKSSGLKLPLPECG
VVIGSSRAYQRMLENLAKKQFVDDGQDHSQKDYGSFINFWPHQPAILTASQIGTKGTVLSPMAACATGILAIARGFELIQ
TGQCQQVIAGAVESPITPLTIAGFRKMGALAQIGAYPFDRAREGFVLGEGAAILLLESANFAKKRSAKVYGQIRSFGLTN
DGIHSVIPDLSGKSAMLAIARSLARSGLAPEEIDYVHAHGTATKLNDRHEANLIQQIFPHKVAVSSTKGATGHTLGASGA
LGAAFCLMAVKHQVLPPCVGLNSPEFDLDLVRYARQSQVKNVLCLSFGFGGQNAALVLSKV
>Mature_381_residues
MKVLVTGIGLTSSLGNLFQSWEKLLDGKSAIRLVKPFAELPPLPLGLINSQPVDLTNLIKQTVETAVKSSGLKLPLPECG
VVIGSSRAYQRMLENLAKKQFVDDGQDHSQKDYGSFINFWPHQPAILTASQIGTKGTVLSPMAACATGILAIARGFELIQ
TGQCQQVIAGAVESPITPLTIAGFRKMGALAQIGAYPFDRAREGFVLGEGAAILLLESANFAKKRSAKVYGQIRSFGLTN
DGIHSVIPDLSGKSAMLAIARSLARSGLAPEEIDYVHAHGTATKLNDRHEANLIQQIFPHKVAVSSTKGATGHTLGASGA
LGAAFCLMAVKHQVLPPCVGLNSPEFDLDLVRYARQSQVKNVLCLSFGFGGQNAALVLSKV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=424, Percent_Identity=33.9622641509434, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI223972627, Length=148, Percent_Identity=43.9189189189189, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI41872631, Length=258, Percent_Identity=29.4573643410853, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1787337, Length=435, Percent_Identity=32.183908045977, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1788663, Length=417, Percent_Identity=28.2973621103118, Blast_Score=125, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71983541, Length=305, Percent_Identity=34.7540983606557, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI71983535, Length=261, Percent_Identity=36.3984674329502, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI212642053, Length=258, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17550940, Length=392, Percent_Identity=26.2755102040816, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=454, Percent_Identity=29.0748898678414, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=33.4939759036145, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24581345, Length=252, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221330659, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19920632, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 40407; Mature: 40407

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGIGLTSSLGNLFQSWEKLLDGKSAIRLVKPFAELPPLPLGLINSQPVDLTNLIK
CEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHH
QTVETAVKSSGLKLPLPECGVVIGSSRAYQRMLENLAKKQFVDDGQDHSQKDYGSFINFW
HHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
PHQPAILTASQIGTKGTVLSPMAACATGILAIARGFELIQTGQCQQVIAGAVESPITPLT
CCCCCEEEHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHCCCCCEE
IAGFRKMGALAQIGAYPFDRAREGFVLGEGAAILLLESANFAKKRSAKVYGQIRSFGLTN
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHCCCCC
DGIHSVIPDLSGKSAMLAIARSLARSGLAPEEIDYVHAHGTATKLNDRHEANLIQQIFPH
CCHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHCCEEECCCCHHCCCCHHHHHHHHHHCCC
KVAVSSTKGATGHTLGASGALGAAFCLMAVKHQVLPPCVGLNSPEFDLDLVRYARQSQVK
CEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
NVLCLSFGFGGQNAALVLSKV
HEEEEEECCCCCCCEEEEECC
>Mature Secondary Structure
MKVLVTGIGLTSSLGNLFQSWEKLLDGKSAIRLVKPFAELPPLPLGLINSQPVDLTNLIK
CEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHH
QTVETAVKSSGLKLPLPECGVVIGSSRAYQRMLENLAKKQFVDDGQDHSQKDYGSFINFW
HHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
PHQPAILTASQIGTKGTVLSPMAACATGILAIARGFELIQTGQCQQVIAGAVESPITPLT
CCCCCEEEHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHCCCCCEE
IAGFRKMGALAQIGAYPFDRAREGFVLGEGAAILLLESANFAKKRSAKVYGQIRSFGLTN
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHCCCCC
DGIHSVIPDLSGKSAMLAIARSLARSGLAPEEIDYVHAHGTATKLNDRHEANLIQQIFPH
CCHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHCCEEECCCCHHCCCCHHHHHHHHHHCCC
KVAVSSTKGATGHTLGASGALGAAFCLMAVKHQVLPPCVGLNSPEFDLDLVRYARQSQVK
CEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
NVLCLSFGFGGQNAALVLSKV
HEEEEEECCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]