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The map label for this gene is pheA [H]

Identifier: 113474348

GI number: 113474348

Start: 759506

End: 760396

Strand: Direct

Name: pheA [H]

Synonym: Tery_0480

Alternate gene names: 113474348

Gene position: 759506-760396 (Clockwise)

Preceding gene: 113474346

Following gene: 113474354

Centisome position: 9.8

GC content: 33.56

Gene sequence:

>891_bases
ATGACTATATCTATTGCACATCTTGGTCCTGCTGGAACTTATACAGAAACGGCAGCAGTGGCATTTTCTGAAAAACTGGG
CCAGCATGGTCAAAAATCTATTCTGTGTCCGTACCCTAGTATTGCTCAAACTTTATCGGCAGTTTCTCAAGAGCAAGTGA
ATTTGGCAGTTGTACCTGTAGAAAATTCTATTGAAGGAAGCGTTACTGTTACTTTAGATACGCTTTGGAAACTGGATATT
TTAGAAATTCAAACAGCATTAGTCTTACCTATTTCTCATGGGTTGATATCACTAGCTACTAGTTTTGAGGAGATTAAAAT
TGTTTATTCTCATCCACAAGCTTTAGCTCAATGTCAAGGTTGGCTAGAAAAGTTTTTACCGCAAGTAAAGCAAGTTCCAG
CTAATTCTACTACAGAAGCATTAGAGCATTTGGAAAAAGAGCGGAGTGCCGGAGCGATCGCTTCTCATAGAGCTGCTAAA
ATTTATAAATTACCTGTATTAGCTTATCCAATTAATGATTATTCTGATAATTGTACTCGCTTTTTGGTATTGAAAAAAGG
ATGTACAGAAATGGAAAATTCAGCTTTTAAACTAATAATTAATACAAGAGATAAGCCAGAAAATTTAGTTTTTACTTCTT
TAGGTTTTACTGTACCTGCAAATGAACCTGGAGCTTTAGTTAAACCATTGCAAGTATTTGCTAAAAGGGAGATTAATATG
AGTAGAATAGAATCTCGTCCAACAAAACTATCTCTAGGTGATTATTTATTTTTTATTGATATAGAAGCTAATATTAATCA
TAATTCTGTTAAGGTAGCGATAGAAGAATTAAAAACCTATACACAAACCCTTAAAATTTTTGGCAGTTATATTCTTATGT
CTATCAATTAA

Upstream 100 bases:

>100_bases
GTTCTTATTCAAGGGGATAAAAAAAAGTCATTTTGGATTTTCTGGCCTCCGGTTTCAGTCAGAGGTACTCATAGCTGATA
ACTGATAACTTATAACTGAA

Downstream 100 bases:

>100_bases
TAGTGATTAGTATTTAATTACCAGTTTGGTTTTGTGATCTTTCCTGACTGTTGATCATAAATATATTCTATATATCTAAA
TACTTTCCTAATATCTAAAT

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTISIAHLGPAGTYTETAAVAFSEKLGQHGQKSILCPYPSIAQTLSAVSQEQVNLAVVPVENSIEGSVTVTLDTLWKLDI
LEIQTALVLPISHGLISLATSFEEIKIVYSHPQALAQCQGWLEKFLPQVKQVPANSTTEALEHLEKERSAGAIASHRAAK
IYKLPVLAYPINDYSDNCTRFLVLKKGCTEMENSAFKLIINTRDKPENLVFTSLGFTVPANEPGALVKPLQVFAKREINM
SRIESRPTKLSLGDYLFFIDIEANINHNSVKVAIEELKTYTQTLKIFGSYILMSIN

Sequences:

>Translated_296_residues
MTISIAHLGPAGTYTETAAVAFSEKLGQHGQKSILCPYPSIAQTLSAVSQEQVNLAVVPVENSIEGSVTVTLDTLWKLDI
LEIQTALVLPISHGLISLATSFEEIKIVYSHPQALAQCQGWLEKFLPQVKQVPANSTTEALEHLEKERSAGAIASHRAAK
IYKLPVLAYPINDYSDNCTRFLVLKKGCTEMENSAFKLIINTRDKPENLVFTSLGFTVPANEPGALVKPLQVFAKREINM
SRIESRPTKLSLGDYLFFIDIEANINHNSVKVAIEELKTYTQTLKIFGSYILMSIN
>Mature_295_residues
TISIAHLGPAGTYTETAAVAFSEKLGQHGQKSILCPYPSIAQTLSAVSQEQVNLAVVPVENSIEGSVTVTLDTLWKLDIL
EIQTALVLPISHGLISLATSFEEIKIVYSHPQALAQCQGWLEKFLPQVKQVPANSTTEALEHLEKERSAGAIASHRAAKI
YKLPVLAYPINDYSDNCTRFLVLKKGCTEMENSAFKLIINTRDKPENLVFTSLGFTVPANEPGALVKPLQVFAKREINMS
RIESRPTKLSLGDYLFFIDIEANINHNSVKVAIEELKTYTQTLKIFGSYILMSIN

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=290, Percent_Identity=30.3448275862069, Blast_Score=119, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324013, Length=340, Percent_Identity=30, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 32619; Mature: 32488

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISIAHLGPAGTYTETAAVAFSEKLGQHGQKSILCPYPSIAQTLSAVSQEQVNLAVVPV
CEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHCCCCEEEEEE
ENSIEGSVTVTLDTLWKLDILEIQTALVLPISHGLISLATSFEEIKIVYSHPQALAQCQG
CCCCCCEEEEEEEHHHEEEHHHHHEEEEEEHHCCHHHHHCCHHHEEEEEECHHHHHHHHH
WLEKFLPQVKQVPANSTTEALEHLEKERSAGAIASHRAAKIYKLPVLAYPINDYSDNCTR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEEEEEEECCCCCCCCEE
FLVLKKGCTEMENSAFKLIINTRDKPENLVFTSLGFTVPANEPGALVKPLQVFAKREINM
EEEEECCCCCCCCCEEEEEEECCCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHCCCCH
SRIESRPTKLSLGDYLFFIDIEANINHNSVKVAIEELKTYTQTLKIFGSYILMSIN
HHHHCCCCEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEC
>Mature Secondary Structure 
TISIAHLGPAGTYTETAAVAFSEKLGQHGQKSILCPYPSIAQTLSAVSQEQVNLAVVPV
EEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHCCCCEEEEEE
ENSIEGSVTVTLDTLWKLDILEIQTALVLPISHGLISLATSFEEIKIVYSHPQALAQCQG
CCCCCCEEEEEEEHHHEEEHHHHHEEEEEEHHCCHHHHHCCHHHEEEEEECHHHHHHHHH
WLEKFLPQVKQVPANSTTEALEHLEKERSAGAIASHRAAKIYKLPVLAYPINDYSDNCTR
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHCCCEEEEEEEEEEEECCCCCCCCEE
FLVLKKGCTEMENSAFKLIINTRDKPENLVFTSLGFTVPANEPGALVKPLQVFAKREINM
EEEEECCCCCCCCCEEEEEEECCCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHCCCCH
SRIESRPTKLSLGDYLFFIDIEANINHNSVKVAIEELKTYTQTLKIFGSYILMSIN
HHHHCCCCEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]