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The map label for this gene is argA [H]

Identifier: 162139945

GI number: 162139945

Start: 2631518

End: 2632846

Strand: Direct

Name: argA [H]

Synonym: ABO_2306

Alternate gene names: 162139945

Gene position: 2631518-2632846 (Clockwise)

Preceding gene: 110835166

Following gene: 110835173

Centisome position: 84.34

GC content: 61.25

Gene sequence:

>1329_bases
GTGTCCACCAGCGCAGCCCCGAACACCGACAGCCAGGTTCACTGGTTCCGCAATTCGTCCCCGTATATCAATGCGCATCG
GGGCCGAACCTTTGTGGTCATGTTGTCTGGGGAACTGCTGGACGGCCCGCGCCTGCCTACCCTGATTCACGATCTGGCCC
TGCTGAATAGCCTGGGAATCAAACTGGTGCTGGTGCATGGCGCCAGGCCACAAATTTCTGCCCGGCTGGCAGAATCCGAC
ATTGAATCCACCTTTGAGCAACACATGCGCATCACCGACAGTGCCGCGCTGGATAGCGTCGTGGCGGCGGTGGGCGCATT
GCGCCTGAAACTGGAAGGCTTGTTCTCCATGGGGCTGGCTAACTCCCCCATGCATAACGCCAGCATCCGGTTAATTAGCG
GCAACTTCGTAGTGGCCAAACCGGTAGGCGTGCGTGGTGGCTTCGACTACCAGCACACCGGTGAAGTGCGGCGCATCGAC
GTAGACGCCATTCGCCAGCAACTGGGCAACGGTAACGTGGTGCTGCTCTCGCCGGTGGGCGGCTCGCCCACCGGCGAACT
GTTCAACGTGAACGCAGAAGAAGTGGCCTCCACTGCCGCCATCGCCCTGGGCGCCGACAAGCTCATCATCATGGGCGAAC
ACCTGCGTCTCGCCGACCCGCAAGGCCACCTGGTGCGCGAACTCAGCCCCCAGCAAGCCGGCAAACTGCTGGCCGGCGAC
CAATACGAAAACAATGGTGTAGACCGGCAGCTCACCGCCGCCTGCCATGCCGCCAGTAACGGCGTGGCTCGGGCGCACCT
GCTCGATGCCCAGGTAGATGGCGCACTAATCAAAGAACTGTTCACCCGCGACGGCTGCGGCACCCTGGTTACTAGGGAAA
CCTACGAAACCCTCCGTGGCGCGCGCATTGAAGACGTGGGCGGCATTCTCGAACTGATCGAACCACTGGAAGAAGACGGC
ACCCTGGTGCGCCGCTCACGGGAGCTACTGGAAAACGAAATTCAGCGCTTCGCCATCATCGAACGCGACGGCATGGTTAT
CGCCTGCGCGGCCCTCTATCCCTTCCCCGAAGAAAAGACCGGCGAACTGGCCTGTGTCGCCGTTCATTCCAGCTACCGCA
AAGGTGAACGGGGCGCACAGGTTCTTGGCTATCTGGAACGGCGGGCACGGGAACAGGGGCTGCACAGCCTATTCGTGCTC
ACCACCCTCACCGCGCACTGGTTTCAGCAACAGGGGTTTGAGGCAGCGGGAGTAGAAGCCCTGCCGGGAGCCAGGCAATC
GCTGTATAACTGGCAGCGGAATTCAAAGGTGTTTGTGAAGGGGCTTTGA

Upstream 100 bases:

>100_bases
CCGGGCGGTTTTTTTGTGTGGGCTCATACGCCCCGCATCTAGTATCCGGCACAATCTGCTCGCTATACTGGCCAATCAAT
CACTTAGAGCCGAGACGCCC

Downstream 100 bases:

>100_bases
AGGTTATGGCCAGATTTCTAGCGCTTGGCCTCAGCCGCCCCCAAAACACGCCAGCGTTTTTGAGTCGCCTGTAGCCCTTT
GTTAGGTTTTGTTCATTCGT

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSTSAAPNTDSQVHWFRNSSPYINAHRGRTFVVMLSGELLDGPRLPTLIHDLALLNSLGIKLVLVHGARPQISARLAESD
IESTFEQHMRITDSAALDSVVAAVGALRLKLEGLFSMGLANSPMHNASIRLISGNFVVAKPVGVRGGFDYQHTGEVRRID
VDAIRQQLGNGNVVLLSPVGGSPTGELFNVNAEEVASTAAIALGADKLIIMGEHLRLADPQGHLVRELSPQQAGKLLAGD
QYENNGVDRQLTAACHAASNGVARAHLLDAQVDGALIKELFTRDGCGTLVTRETYETLRGARIEDVGGILELIEPLEEDG
TLVRRSRELLENEIQRFAIIERDGMVIACAALYPFPEEKTGELACVAVHSSYRKGERGAQVLGYLERRAREQGLHSLFVL
TTLTAHWFQQQGFEAAGVEALPGARQSLYNWQRNSKVFVKGL

Sequences:

>Translated_442_residues
MSTSAAPNTDSQVHWFRNSSPYINAHRGRTFVVMLSGELLDGPRLPTLIHDLALLNSLGIKLVLVHGARPQISARLAESD
IESTFEQHMRITDSAALDSVVAAVGALRLKLEGLFSMGLANSPMHNASIRLISGNFVVAKPVGVRGGFDYQHTGEVRRID
VDAIRQQLGNGNVVLLSPVGGSPTGELFNVNAEEVASTAAIALGADKLIIMGEHLRLADPQGHLVRELSPQQAGKLLAGD
QYENNGVDRQLTAACHAASNGVARAHLLDAQVDGALIKELFTRDGCGTLVTRETYETLRGARIEDVGGILELIEPLEEDG
TLVRRSRELLENEIQRFAIIERDGMVIACAALYPFPEEKTGELACVAVHSSYRKGERGAQVLGYLERRAREQGLHSLFVL
TTLTAHWFQQQGFEAAGVEALPGARQSLYNWQRNSKVFVKGL
>Mature_441_residues
STSAAPNTDSQVHWFRNSSPYINAHRGRTFVVMLSGELLDGPRLPTLIHDLALLNSLGIKLVLVHGARPQISARLAESDI
ESTFEQHMRITDSAALDSVVAAVGALRLKLEGLFSMGLANSPMHNASIRLISGNFVVAKPVGVRGGFDYQHTGEVRRIDV
DAIRQQLGNGNVVLLSPVGGSPTGELFNVNAEEVASTAAIALGADKLIIMGEHLRLADPQGHLVRELSPQQAGKLLAGDQ
YENNGVDRQLTAACHAASNGVARAHLLDAQVDGALIKELFTRDGCGTLVTRETYETLRGARIEDVGGILELIEPLEEDGT
LVRRSRELLENEIQRFAIIERDGMVIACAALYPFPEEKTGELACVAVHSSYRKGERGAQVLGYLERRAREQGLHSLFVLT
TLTAHWFQQQGFEAAGVEALPGARQSLYNWQRNSKVFVKGL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=433, Percent_Identity=48.729792147806, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 47988; Mature: 47857

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSAAPNTDSQVHWFRNSSPYINAHRGRTFVVMLSGELLDGPRLPTLIHDLALLNSLGI
CCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCE
KLVLVHGARPQISARLAESDIESTFEQHMRITDSAALDSVVAAVGALRLKLEGLFSMGLA
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NSPMHNASIRLISGNFVVAKPVGVRGGFDYQHTGEVRRIDVDAIRQQLGNGNVVLLSPVG
CCCCCCCEEEEEECCEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEEECCC
GSPTGELFNVNAEEVASTAAIALGADKLIIMGEHLRLADPQGHLVRELSPQQAGKLLAGD
CCCCCCEEECCHHHHHHHHHEEECCCEEEEEECCEEECCCCCHHHHHCCHHHHCCCCCCC
QYENNGVDRQLTAACHAASNGVARAHLLDAQVDGALIKELFTRDGCGTLVTRETYETLRG
CCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHCCCCCCEEEHHHHHHHCC
ARIEDVGGILELIEPLEEDGTLVRRSRELLENEIQRFAIIERDGMVIACAALYPFPEEKT
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCEEEEEEEECCCCCCCC
GELACVAVHSSYRKGERGAQVLGYLERRAREQGLHSLFVLTTLTAHWFQQQGFEAAGVEA
CCEEEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LPGARQSLYNWQRNSKVFVKGL
CCCHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure 
STSAAPNTDSQVHWFRNSSPYINAHRGRTFVVMLSGELLDGPRLPTLIHDLALLNSLGI
CCCCCCCCCCCEEEEECCCCEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCE
KLVLVHGARPQISARLAESDIESTFEQHMRITDSAALDSVVAAVGALRLKLEGLFSMGLA
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NSPMHNASIRLISGNFVVAKPVGVRGGFDYQHTGEVRRIDVDAIRQQLGNGNVVLLSPVG
CCCCCCCEEEEEECCEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCEEEEECCC
GSPTGELFNVNAEEVASTAAIALGADKLIIMGEHLRLADPQGHLVRELSPQQAGKLLAGD
CCCCCCEEECCHHHHHHHHHEEECCCEEEEEECCEEECCCCCHHHHHCCHHHHCCCCCCC
QYENNGVDRQLTAACHAASNGVARAHLLDAQVDGALIKELFTRDGCGTLVTRETYETLRG
CCCCCCCCHHHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHCCCCCCEEEHHHHHHHCC
ARIEDVGGILELIEPLEEDGTLVRRSRELLENEIQRFAIIERDGMVIACAALYPFPEEKT
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCEEEEEEEECCCCCCCC
GELACVAVHSSYRKGERGAQVLGYLERRAREQGLHSLFVLTTLTAHWFQQQGFEAAGVEA
CCEEEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
LPGARQSLYNWQRNSKVFVKGL
CCCHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA