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The map label for this gene is pitA [C]

Identifier: 110835166

GI number: 110835166

Start: 2630115

End: 2631383

Strand: Direct

Name: pitA [C]

Synonym: ABO_2305

Alternate gene names: 110835166

Gene position: 2630115-2631383 (Clockwise)

Preceding gene: 110835165

Following gene: 162139945

Centisome position: 84.29

GC content: 60.68

Gene sequence:

>1269_bases
ATGGAGTGGATGCTAGAGCATAGCTATTTCATGCTGCTGCTGGCGGGCGCCTTCGGGTTCCTAATGGCCTGGGGCGTTGG
CGCCAACGATGTGGCCAACGCCATGGGGACCTCGGTGGGAGCCAAGGCCCTCACCGTGAAGCAGGCGGTTATCATCGCCA
TTATCTTTGAATTTGCCGGGGCCTACCTGGCCGGCGGCGAAGTCACCGCCACCATCCGCAAGGGCATCATCGATGCGGAT
GCCTTCTCCCACGCCCCGCAATACTTGGTCTACGGCATGATGTCCGCATTGCTGGCCGCCGGTATCTGGTTGATGGTGGC
GTCCTGGTTCGGTTGGCCGGTCTCCACCACCCATTCCATCGTCGGTGCCATCGTCGGCTTTGCCGCCGTAGGCTTGGGCA
TGGACGCGGTGCACTGGGGCAAGGTGGGCTCCATCGTCGCTAGCTGGGTCACCTCGCCCCTGCTGGCCGGGATCATTTCC
TTTGCCCTAATCCGTAGCGTGCAACGGTTGGTACTGAACCACGACGACCCCTTCGAACGCGCCAAGAAAGTCGTCCCTTT
CTACATGTTCTTGGTGGGCTTTGTTATTTCCATGGTCACCATGGTCAAAGGGTTGAAACACGTCGGTCTGGAACTGAGTT
TCTTCCACAGTTTCCTGTGGGCCCTGCTGGGTGGCGCGGTTGTTATGGCACTGGGAAGCTTCTTCCTGAGTCGGGTTGAA
CCAGACCCAGAAGCCGATAAAGACTTCCGGTTCAGCTCTGTGGAGCGCGTGTTTGCGGTACTCATGATCTTCACCGCCTG
CGCCATGGCGTTTGCCCACGGCTCCAACGATGTAGCCAACGCCGTCGGCCCGCTGGCCGCCATCAACAGCGTACTGGCGT
CCGGCGGCGAAATCGGCGCCAAAGCAGAAATGCCCAGCTGGATTCTTTTGGTCGGGGCCATGGGTATCGTCTTTGGGCTA
GCGATTTTCGGCGCCCGAGTGATGGCCACTGTAGGCAAAAAGATTACCGAGCTCACCCCATCCCGTGGCTTCGCCGCCGA
GCTGGGCGCCGCCACCACCGTGGTGCTGGCCTCCAGCACCGGCCTGCCCATTTCCACCACTCACACCCTGGTGGGCGCGG
TCTTGGGCGTCGGCATGGCCCGCGGCATTGGCTCTCTGAACCTGCGTGTAATCAGCACCATCTTCACCTCTTGGGTCGTC
ACCCTGCCCGCCGGTGCGCTGCTCTCCATCCTGTTCTTCTATTTCTTCAAAGGGCTGTTTGGGGCATAG

Upstream 100 bases:

>100_bases
TTCCTCTACAAGATCATCGAATGGGTGGGCGATCTCGCCGATCGCGCCCAGAAAGTGGGCGGCCGCCTGCAGATGTTGGT
CGCACGCTAGGAGAGTTCTT

Downstream 100 bases:

>100_bases
CAAAAAGGCTTCACGCACACAGAAAAGCCGCCCTCCGGGCGGTTTTTTTGTGTGGGCTCATACGCCCCGCATCTAGTATC
CGGCACAATCTGCTCGCTAT

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MEWMLEHSYFMLLLAGAFGFLMAWGVGANDVANAMGTSVGAKALTVKQAVIIAIIFEFAGAYLAGGEVTATIRKGIIDAD
AFSHAPQYLVYGMMSALLAAGIWLMVASWFGWPVSTTHSIVGAIVGFAAVGLGMDAVHWGKVGSIVASWVTSPLLAGIIS
FALIRSVQRLVLNHDDPFERAKKVVPFYMFLVGFVISMVTMVKGLKHVGLELSFFHSFLWALLGGAVVMALGSFFLSRVE
PDPEADKDFRFSSVERVFAVLMIFTACAMAFAHGSNDVANAVGPLAAINSVLASGGEIGAKAEMPSWILLVGAMGIVFGL
AIFGARVMATVGKKITELTPSRGFAAELGAATTVVLASSTGLPISTTHTLVGAVLGVGMARGIGSLNLRVISTIFTSWVV
TLPAGALLSILFFYFFKGLFGA

Sequences:

>Translated_422_residues
MEWMLEHSYFMLLLAGAFGFLMAWGVGANDVANAMGTSVGAKALTVKQAVIIAIIFEFAGAYLAGGEVTATIRKGIIDAD
AFSHAPQYLVYGMMSALLAAGIWLMVASWFGWPVSTTHSIVGAIVGFAAVGLGMDAVHWGKVGSIVASWVTSPLLAGIIS
FALIRSVQRLVLNHDDPFERAKKVVPFYMFLVGFVISMVTMVKGLKHVGLELSFFHSFLWALLGGAVVMALGSFFLSRVE
PDPEADKDFRFSSVERVFAVLMIFTACAMAFAHGSNDVANAVGPLAAINSVLASGGEIGAKAEMPSWILLVGAMGIVFGL
AIFGARVMATVGKKITELTPSRGFAAELGAATTVVLASSTGLPISTTHTLVGAVLGVGMARGIGSLNLRVISTIFTSWVV
TLPAGALLSILFFYFFKGLFGA
>Mature_422_residues
MEWMLEHSYFMLLLAGAFGFLMAWGVGANDVANAMGTSVGAKALTVKQAVIIAIIFEFAGAYLAGGEVTATIRKGIIDAD
AFSHAPQYLVYGMMSALLAAGIWLMVASWFGWPVSTTHSIVGAIVGFAAVGLGMDAVHWGKVGSIVASWVTSPLLAGIIS
FALIRSVQRLVLNHDDPFERAKKVVPFYMFLVGFVISMVTMVKGLKHVGLELSFFHSFLWALLGGAVVMALGSFFLSRVE
PDPEADKDFRFSSVERVFAVLMIFTACAMAFAHGSNDVANAVGPLAAINSVLASGGEIGAKAEMPSWILLVGAMGIVFGL
AIFGARVMATVGKKITELTPSRGFAAELGAATTVVLASSTGLPISTTHTLVGAVLGVGMARGIGSLNLRVISTIFTSWVV
TLPAGALLSILFFYFFKGLFGA

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=185, Percent_Identity=43.2432432432432, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI5803173, Length=185, Percent_Identity=40, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI1789907, Length=107, Percent_Identity=40.1869158878505, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789360, Length=107, Percent_Identity=40.1869158878505, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71981576, Length=429, Percent_Identity=36.5967365967366, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI32566716, Length=484, Percent_Identity=34.7107438016529, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17557328, Length=493, Percent_Identity=27.3833671399594, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17539280, Length=201, Percent_Identity=39.8009950248756, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI25146401, Length=175, Percent_Identity=45.1428571428571, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17536725, Length=167, Percent_Identity=35.3293413173653, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319773, Length=162, Percent_Identity=40.1234567901235, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21356511, Length=241, Percent_Identity=37.344398340249, Blast_Score=155, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 44367; Mature: 44367

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure
MEWMLEHSYFMLLLAGAFGFLMAWGVGANDVANAMGTSVGAKALTVKQAVIIAIIFEFAG
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AYLAGGEVTATIRKGIIDADAFSHAPQYLVYGMMSALLAAGIWLMVASWFGWPVSTTHSI
HHHCCCCHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VGAIVGFAAVGLGMDAVHWGKVGSIVASWVTSPLLAGIISFALIRSVQRLVLNHDDPFER
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AKKVVPFYMFLVGFVISMVTMVKGLKHVGLELSFFHSFLWALLGGAVVMALGSFFLSRVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDPEADKDFRFSSVERVFAVLMIFTACAMAFAHGSNDVANAVGPLAAINSVLASGGEIGA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCC
KAEMPSWILLVGAMGIVFGLAIFGARVMATVGKKITELTPSRGFAAELGAATTVVLASST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHEEEEECCC
GLPISTTHTLVGAVLGVGMARGIGSLNLRVISTIFTSWVVTLPAGALLSILFFYFFKGLF
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
GA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]