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The map label for this gene is gap [H]

Identifier: 110835475

GI number: 110835475

Start: 2956939

End: 2957973

Strand: Reverse

Name: gap [H]

Synonym: ABO_2614

Alternate gene names: 110835475

Gene position: 2957973-2956939 (Counterclockwise)

Preceding gene: 110835476

Following gene: 110835474

Centisome position: 94.8

GC content: 57.29

Gene sequence:

>1035_bases
ATGCGCATCGCCATTAATGGCTATGGCCGTATTGGGCGTTCTTTTGTCCGTGCTCTGGCCGAGCGCGAAGGCGCAGGTTG
GCAGGCGCCGTTTACGTTGGTGGCGATCAACGACAAGGGCCGCCCGGAAGATTTGTTGTACCTGACGCGTTACGACACCA
CCCACGGGCGGCTGGCGGAGCCGGCTGAGTTGATTGATGGGATGCTGCGTATTGGCAAACAGGCGCCCATGTTGCTGGAG
CAACCACAGCCAGAGTTGCTGCCTTGGGGTGAGCTCGGGGTGGACTTAGTGCTGGAGTGTTCCGGGCATTTTCGCAGCCA
TGCGGGCGCGTCTCGTCACCTACAAGCCGGTGCGAAAAAAGTCATTATCGGTGCGGTGCCGTTTGATCAAGCGGATCAAA
TCGTGGTGTACGGCGTCAATCATGAGGACGTTCGTGACGACAGCCAGGTGCTGTCGGCGGCGTCTTGTACTACGCACTGC
ATTGCTCCGCTGCTGCAGCGGCTAGACCAGCAGTATGGTGTTCAGCAGGTATTGATGAAAGAAATCCATGCTTACACCTC
GGATCAGACCTTGCTGGATCACGTTCATCGGGACCCGCGCCGGGGGCGGGCCGGAGCACAGAACATCGTGCCCACCACCA
GCAGTTCCATTGGTGCGGTACAACAAGTATTGCCGGCGCTGGCTGGGCGCATCAATGGTGACTCCATTCGAGTGCCAACC
CTAAATGTGGCTATGGTGGAGCTGACTTTGCGGTTGGAACAGACACCGGATGAAGACAGTCTTAATCAGTGGCTACACCA
ACAGGCAACCGTGTCGGCGGGCCTGATTGGCTACAATGACGCGCCGCTGGTCAGCGCGGATTTTAATCACCGTACAGAGT
CCGCGATCGTTGATGTGACTCAGACCCGAGTGCAGGGCGATATGGTGCAAGTAGTGGCTTGGTACGACAACGAATGGGGT
TATGCCAACCGATTGTTGGACTGGGTGAATGAATTAGCTTTGAACAAGGCTGGATGCTCTAAGCTGGGCGCCTGA

Upstream 100 bases:

>100_bases
ATCACCGCTGAAGCCGTACAGGAAGCAGTGGAGTCGTTGTTGTAATGAAACGCCGGACGCCTGGTGCTGGGCACGTGACG
CTGCTGCGGAGCGCTGTCTA

Downstream 100 bases:

>100_bases
CGTGTTGCTTAAACGTTTGGCGTCAGCATGGCGTCTGGCAGAATTTAATGAGGTAGGAACGAAATGAACTTCAAACGCAT
GACCGACCTGGATCTGGCAG

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRIAINGYGRIGRSFVRALAEREGAGWQAPFTLVAINDKGRPEDLLYLTRYDTTHGRLAEPAELIDGMLRIGKQAPMLLE
QPQPELLPWGELGVDLVLECSGHFRSHAGASRHLQAGAKKVIIGAVPFDQADQIVVYGVNHEDVRDDSQVLSAASCTTHC
IAPLLQRLDQQYGVQQVLMKEIHAYTSDQTLLDHVHRDPRRGRAGAQNIVPTTSSSIGAVQQVLPALAGRINGDSIRVPT
LNVAMVELTLRLEQTPDEDSLNQWLHQQATVSAGLIGYNDAPLVSADFNHRTESAIVDVTQTRVQGDMVQVVAWYDNEWG
YANRLLDWVNELALNKAGCSKLGA

Sequences:

>Translated_344_residues
MRIAINGYGRIGRSFVRALAEREGAGWQAPFTLVAINDKGRPEDLLYLTRYDTTHGRLAEPAELIDGMLRIGKQAPMLLE
QPQPELLPWGELGVDLVLECSGHFRSHAGASRHLQAGAKKVIIGAVPFDQADQIVVYGVNHEDVRDDSQVLSAASCTTHC
IAPLLQRLDQQYGVQQVLMKEIHAYTSDQTLLDHVHRDPRRGRAGAQNIVPTTSSSIGAVQQVLPALAGRINGDSIRVPT
LNVAMVELTLRLEQTPDEDSLNQWLHQQATVSAGLIGYNDAPLVSADFNHRTESAIVDVTQTRVQGDMVQVVAWYDNEWG
YANRLLDWVNELALNKAGCSKLGA
>Mature_344_residues
MRIAINGYGRIGRSFVRALAEREGAGWQAPFTLVAINDKGRPEDLLYLTRYDTTHGRLAEPAELIDGMLRIGKQAPMLLE
QPQPELLPWGELGVDLVLECSGHFRSHAGASRHLQAGAKKVIIGAVPFDQADQIVVYGVNHEDVRDDSQVLSAASCTTHC
IAPLLQRLDQQYGVQQVLMKEIHAYTSDQTLLDHVHRDPRRGRAGAQNIVPTTSSSIGAVQQVLPALAGRINGDSIRVPT
LNVAMVELTLRLEQTPDEDSLNQWLHQQATVSAGLIGYNDAPLVSADFNHRTESAIVDVTQTRVQGDMVQVVAWYDNEWG
YANRLLDWVNELALNKAGCSKLGA

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=337, Percent_Identity=35.6083086053413, Blast_Score=218, Evalue=5e-57,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=35.2409638554217, Blast_Score=211, Evalue=1e-54,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=40.4255319148936, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1788079, Length=336, Percent_Identity=35.7142857142857, Blast_Score=222, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17534679, Length=343, Percent_Identity=36.4431486880466, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17534677, Length=343, Percent_Identity=36.4431486880466, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI32566163, Length=341, Percent_Identity=36.0703812316716, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17568413, Length=341, Percent_Identity=36.0703812316716, Blast_Score=205, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6322409, Length=337, Percent_Identity=35.9050445103858, Blast_Score=223, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6322468, Length=337, Percent_Identity=35.3115727002967, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6321631, Length=337, Percent_Identity=35.6083086053413, Blast_Score=219, Evalue=5e-58,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=35.8208955223881, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=35.8208955223881, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=36.144578313253, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=35.8208955223881, Blast_Score=212, Evalue=2e-55,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=35.8208955223881, Blast_Score=212, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37778; Mature: 37778

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAINGYGRIGRSFVRALAEREGAGWQAPFTLVAINDKGRPEDLLYLTRYDTTHGRLAE
CEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCC
PAELIDGMLRIGKQAPMLLEQPQPELLPWGELGVDLVLECSGHFRSHAGASRHLQAGAKK
HHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCEEEEEECCCCHHHCCCCHHHHHCCCCE
VIIGAVPFDQADQIVVYGVNHEDVRDDSQVLSAASCTTHCIAPLLQRLDQQYGVQQVLMK
EEEEECCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
EIHAYTSDQTLLDHVHRDPRRGRAGAQNIVPTTSSSIGAVQQVLPALAGRINGDSIRVPT
HHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCC
LNVAMVELTLRLEQTPDEDSLNQWLHQQATVSAGLIGYNDAPLVSADFNHRTESAIVDVT
CEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCEECCCCCCEEECCCCCCCHHHHHHHH
QTRVQGDMVQVVAWYDNEWGYANRLLDWVNELALNKAGCSKLGA
HHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCHHCHHHCCC
>Mature Secondary Structure
MRIAINGYGRIGRSFVRALAEREGAGWQAPFTLVAINDKGRPEDLLYLTRYDTTHGRLAE
CEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCC
PAELIDGMLRIGKQAPMLLEQPQPELLPWGELGVDLVLECSGHFRSHAGASRHLQAGAKK
HHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCEEEEEECCCCHHHCCCCHHHHHCCCCE
VIIGAVPFDQADQIVVYGVNHEDVRDDSQVLSAASCTTHCIAPLLQRLDQQYGVQQVLMK
EEEEECCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
EIHAYTSDQTLLDHVHRDPRRGRAGAQNIVPTTSSSIGAVQQVLPALAGRINGDSIRVPT
HHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCC
LNVAMVELTLRLEQTPDEDSLNQWLHQQATVSAGLIGYNDAPLVSADFNHRTESAIVDVT
CEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCEECCCCCCEEECCCCCCCHHHHHHHH
QTRVQGDMVQVVAWYDNEWGYANRLLDWVNELALNKAGCSKLGA
HHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7763137 [H]