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The map label for this gene is pgk

Identifier: 110835474

GI number: 110835474

Start: 2955712

End: 2956875

Strand: Reverse

Name: pgk

Synonym: ABO_2613

Alternate gene names: 110835474

Gene position: 2956875-2955712 (Counterclockwise)

Preceding gene: 110835475

Following gene: 110835473

Centisome position: 94.77

GC content: 55.84

Gene sequence:

>1164_bases
ATGAACTTCAAACGCATGACCGACCTGGATCTGGCAGGCAAACGCGTTCTGATCCGTGAAGACCTGAACGTGCCGGTGAA
GGATGGCAAGGTCACCAGTGATGCGCGCATCCGTGCCTCATTGCCGACCATTGAACATGCGCTCAAGGCCGGCGCCAAGG
TGATGCTGATGTCTCATCTGGGGCGTCCAACCGAAGGTGAGTATGCGGAGGAATTTTCTCTGCAGCCGGTGGCCGATCAT
TTGGGAGGTCTGCTGGGCCGTGATGTACCGCTAGTGAAAGATTGGCTGGGCGGCGTCGAGGTGGCGGACGGTCAGGTGGT
GTTGTGTGAGAACGTTCGCTTCAATCAAGGTGAAAAGAAAGACGACGAAGCACTGTCACAAAAAATGGCGGCACTGTGTG
ATATCTATGTAATGGATGCCTTTGGTACGGCACACCGTGCGCAGGCATCCACCCATGGGGTGGGCAAATTTGCGCCTGTG
GCATGTGCCGGCCCGCTGCTGGCCAATGAGCTGGATGCCTTAGGTAAGGCGCTGGATGCACCCGCCAAACCCTTGGTGGC
CATTGTGGGTGGCTCCAAGGTGTCCACCAAGCTGGAAGTGCTGGAATCGTTGTCGGATAAAGTGGATCAGTTGGTGGTTG
GTGGCGGTATCGCCAACACCTTCCTGGCCGCTGCCGGGCACCCGGTGGGTAAGTCTTTGTATGAAAAGGACCTGATTCCT
GCCGCACAGAAAATTGCCGAGAAGGTACACATCCCGATTCCGGTGGATGTGGTTACTGCCAAGGCCTTTTCTGAATCCGC
CGAGGCGGCGACCAAGAAAGTGGAAGACGTGGCCGACGACGACATGATTTTGGATGTGGGCCCGCAAACAGCTCACATCG
TGGCGGCACTAATGAAAGAAGCCAAAACCATTATTTGGAATGGTCCGGTGGGTGTTTTTGAATTTGATCAGTTTGGTGAA
GGCACTCGTGAAATGGCCCTGGCCATCGCCGATTCTGATGCTTTCTCCATTGCTGGCGGTGGCGACACCCTGGCGGCGGT
GGATAAATACGGCATTACCGATAAGGTTAGCTACATCTCTACCGGTGGTGGTGCCTTCCTGGAGTTTGTGGAAGGTAAGG
TGCTGCCGGCAGTGGCTATGCTTGAGGCACGGGCGAAGGATTGA

Upstream 100 bases:

>100_bases
TTTGAACAAGGCTGGATGCTCTAAGCTGGGCGCCTGACGTGTTGCTTAAACGTTTGGCGTCAGCATGGCGTCTGGCAGAA
TTTAATGAGGTAGGAACGAA

Downstream 100 bases:

>100_bases
TAAAACGCCGAATGCTCGACGCCGAAGGCCTGACGACAACTCGTACGTTAGGCGTTTGGTTTTTGACATCGGGTTGTAAT
GGACGAAGCATAGGCGGTGC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNFKRMTDLDLAGKRVLIREDLNVPVKDGKVTSDARIRASLPTIEHALKAGAKVMLMSHLGRPTEGEYAEEFSLQPVADH
LGGLLGRDVPLVKDWLGGVEVADGQVVLCENVRFNQGEKKDDEALSQKMAALCDIYVMDAFGTAHRAQASTHGVGKFAPV
ACAGPLLANELDALGKALDAPAKPLVAIVGGSKVSTKLEVLESLSDKVDQLVVGGGIANTFLAAAGHPVGKSLYEKDLIP
AAQKIAEKVHIPIPVDVVTAKAFSESAEAATKKVEDVADDDMILDVGPQTAHIVAALMKEAKTIIWNGPVGVFEFDQFGE
GTREMALAIADSDAFSIAGGGDTLAAVDKYGITDKVSYISTGGGAFLEFVEGKVLPAVAMLEARAKD

Sequences:

>Translated_387_residues
MNFKRMTDLDLAGKRVLIREDLNVPVKDGKVTSDARIRASLPTIEHALKAGAKVMLMSHLGRPTEGEYAEEFSLQPVADH
LGGLLGRDVPLVKDWLGGVEVADGQVVLCENVRFNQGEKKDDEALSQKMAALCDIYVMDAFGTAHRAQASTHGVGKFAPV
ACAGPLLANELDALGKALDAPAKPLVAIVGGSKVSTKLEVLESLSDKVDQLVVGGGIANTFLAAAGHPVGKSLYEKDLIP
AAQKIAEKVHIPIPVDVVTAKAFSESAEAATKKVEDVADDDMILDVGPQTAHIVAALMKEAKTIIWNGPVGVFEFDQFGE
GTREMALAIADSDAFSIAGGGDTLAAVDKYGITDKVSYISTGGGAFLEFVEGKVLPAVAMLEARAKD
>Mature_387_residues
MNFKRMTDLDLAGKRVLIREDLNVPVKDGKVTSDARIRASLPTIEHALKAGAKVMLMSHLGRPTEGEYAEEFSLQPVADH
LGGLLGRDVPLVKDWLGGVEVADGQVVLCENVRFNQGEKKDDEALSQKMAALCDIYVMDAFGTAHRAQASTHGVGKFAPV
ACAGPLLANELDALGKALDAPAKPLVAIVGGSKVSTKLEVLESLSDKVDQLVVGGGIANTFLAAAGHPVGKSLYEKDLIP
AAQKIAEKVHIPIPVDVVTAKAFSESAEAATKKVEDVADDDMILDVGPQTAHIVAALMKEAKTIIWNGPVGVFEFDQFGE
GTREMALAIADSDAFSIAGGGDTLAAVDKYGITDKVSYISTGGGAFLEFVEGKVLPAVAMLEARAKD

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI31543397, Length=414, Percent_Identity=40.8212560386473, Blast_Score=287, Evalue=1e-77,
Organism=Homo sapiens, GI4505763, Length=407, Percent_Identity=41.5233415233415, Blast_Score=285, Evalue=4e-77,
Organism=Escherichia coli, GI1789294, Length=386, Percent_Identity=72.279792746114, Blast_Score=555, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI17508823, Length=415, Percent_Identity=46.5060240963855, Blast_Score=323, Evalue=8e-89,
Organism=Saccharomyces cerevisiae, GI6319857, Length=412, Percent_Identity=42.9611650485437, Blast_Score=289, Evalue=4e-79,
Organism=Drosophila melanogaster, GI17136394, Length=417, Percent_Identity=44.1247002398081, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24581203, Length=411, Percent_Identity=40.1459854014599, Blast_Score=265, Evalue=5e-71,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_ALCBS (Q0VL87)

Other databases:

- EMBL:   AM286690
- RefSeq:   YP_694333.1
- ProteinModelPortal:   Q0VL87
- SMR:   Q0VL87
- STRING:   Q0VL87
- GeneID:   4211326
- GenomeReviews:   AM286690_GR
- KEGG:   abo:ABO_2613
- NMPDR:   fig|393595.12.peg.2620
- eggNOG:   COG0126
- HOGENOM:   HBG453500
- OMA:   CEESMID
- PhylomeDB:   Q0VL87
- ProtClustDB:   PRK00073
- BioCyc:   ABOR393595:ABO_2613-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 40712; Mature: 40712

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 36-36 BINDING 113-113 BINDING 146-146 BINDING 197-197 BINDING 314-314

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKRMTDLDLAGKRVLIREDLNVPVKDGKVTSDARIRASLPTIEHALKAGAKVMLMSHL
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHC
GRPTEGEYAEEFSLQPVADHLGGLLGRDVPLVKDWLGGVEVADGQVVLCENVRFNQGEKK
CCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCEEECCCCEEEECCCCCCCCCCC
DDEALSQKMAALCDIYVMDAFGTAHRAQASTHGVGKFAPVACAGPLLANELDALGKALDA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCC
PAKPLVAIVGGSKVSTKLEVLESLSDKVDQLVVGGGIANTFLAAAGHPVGKSLYEKDLIP
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHH
AAQKIAEKVHIPIPVDVVTAKAFSESAEAATKKVEDVADDDMILDVGPQTAHIVAALMKE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
AKTIIWNGPVGVFEFDQFGEGTREMALAIADSDAFSIAGGGDTLAAVDKYGITDKVSYIS
CCEEEECCCCCEEECHHHCCCCHHEEEEEECCCCEEEECCCCCHHHHHHCCCCCCHHEEE
TGGGAFLEFVEGKVLPAVAMLEARAKD
CCCHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFKRMTDLDLAGKRVLIREDLNVPVKDGKVTSDARIRASLPTIEHALKAGAKVMLMSHL
CCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHCCHHHHHHHHC
GRPTEGEYAEEFSLQPVADHLGGLLGRDVPLVKDWLGGVEVADGQVVLCENVRFNQGEKK
CCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCEEECCCCEEEECCCCCCCCCCC
DDEALSQKMAALCDIYVMDAFGTAHRAQASTHGVGKFAPVACAGPLLANELDALGKALDA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCC
PAKPLVAIVGGSKVSTKLEVLESLSDKVDQLVVGGGIANTFLAAAGHPVGKSLYEKDLIP
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHHHH
AAQKIAEKVHIPIPVDVVTAKAFSESAEAATKKVEDVADDDMILDVGPQTAHIVAALMKE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
AKTIIWNGPVGVFEFDQFGEGTREMALAIADSDAFSIAGGGDTLAAVDKYGITDKVSYIS
CCEEEECCCCCEEECHHHCCCCHHEEEEEECCCCEEEECCCCCHHHHHHCCCCCCHHEEE
TGGGAFLEFVEGKVLPAVAMLEARAKD
CCCHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA