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The map label for this gene is cobT [H]

Identifier: 110835239

GI number: 110835239

Start: 2702834

End: 2703973

Strand: Direct

Name: cobT [H]

Synonym: ABO_2378

Alternate gene names: 110835239

Gene position: 2702834-2703973 (Clockwise)

Preceding gene: 110835236

Following gene: 110835240

Centisome position: 86.63

GC content: 63.42

Gene sequence:

>1140_bases
ATGGCGGGCAGTGTACTTGACACTCCCGGTTGCGGGGCAGAGGATTTGCCGCTTTCCGGCCCTGCGCCGCCCCAACCGGA
GACACTCGTGAGTACGCCTTTCCCTTGGCAACAGCCGATTGCCGCCCCCAGCGAACCCCATCGGCAAGCCGCCCTGCACC
GCCAAGCCCAGCTCACCAAACCCGCCGGCTCACTAGGCGAACTTGAATCTCTGGCGGTCACCCTGGCGGGCCTGCAGGCG
ACAAACCTGCCACGCATTGAGCAGGTTTGCATTGCCGTTTTCGCCGCCGACCATGGCGTCTGCGAGGAAGGCATCTCCGC
CTTTCCCCAAGCCGTCACCGGGCAGATGATTGCCAATTTTGTTGCTGGCGGAGCTGCCATCAGTGTCATGGCAAAACAAC
TAGGCGCCGCTCTGGAAGTAATCAACCTGGGCACCGTCAGCCCGCTGCCCATTGACGACGGCGTGATTGATGAACACATC
GCCCCGGGCACCGGAAACCTAGCCCGCCAACCCGCCATGACCGACGACCAATTGCAGGCCGCACTCGCCGCCGGAGATCG
CGCTGCGCAACGGGCCGCCGATCGCCAAGCCGACGTGTTTATTGGCGGGGAGATGGGCATTGGCAACACCACCAGCGCCA
CCGCCCTGGCCTGCGCACTATTAGGCGAAGACGCCACCGCACTCACCGGCCCTGGCACCGGGCTGACACCAGAAGGCGTT
GCCCACAAAGCCCAAGTGATTGCCCAGGCCCTAGCCCGTCACGGCACCCGGCCCGAACCGTTGGCCGTGCTGGCCTCTTT
GGGGGGCTTTGAAATCGTCGCTCTGGCTGGCGCCTTTATCGGCTGCGCGGTACGCGGCATCCCGGTATTAGTGGACGGTT
TTATTGTCTCCACAGCAGCCCTTGCCGCCTGCCAACTTCGACCACAATTACGCCCCTGGTTACTGTTCGCCCACCAGTCA
CGCGAGCCCGGCCACCAACGGCTGCTGCACGCCCTGGACGCCACCCCGCTGCTGGATCTTTCCCTACGCTTGGGCGAAGG
CAGTGGCGCGGCTGTAGCAGTACCGTTATTACGCAATGCCTGCGCGCTACACAATCATATGGCGACCTTTGCCGACGCCA
ATGTCAGCAACGAAAACTAA

Upstream 100 bases:

>100_bases
CGACGCGGCTCGCCCAGCAAAAAATCCAGCACAATCGCTGCCACAGCAGCACTTATCAGGGAAACAGAAAGCATGATTTT
GCCGTCATTGTCCGGTATCG

Downstream 100 bases:

>100_bases
TTTTGCCGGATTACAGTAACGCCGAAGCCAACCTACAAGAACGGGAATAGATACCGATGAGCACCACTATTTTTGACCTG
ATTCGTCATGGTGAACCCGC

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MAGSVLDTPGCGAEDLPLSGPAPPQPETLVSTPFPWQQPIAAPSEPHRQAALHRQAQLTKPAGSLGELESLAVTLAGLQA
TNLPRIEQVCIAVFAADHGVCEEGISAFPQAVTGQMIANFVAGGAAISVMAKQLGAALEVINLGTVSPLPIDDGVIDEHI
APGTGNLARQPAMTDDQLQAALAAGDRAAQRAADRQADVFIGGEMGIGNTTSATALACALLGEDATALTGPGTGLTPEGV
AHKAQVIAQALARHGTRPEPLAVLASLGGFEIVALAGAFIGCAVRGIPVLVDGFIVSTAALAACQLRPQLRPWLLFAHQS
REPGHQRLLHALDATPLLDLSLRLGEGSGAAVAVPLLRNACALHNHMATFADANVSNEN

Sequences:

>Translated_379_residues
MAGSVLDTPGCGAEDLPLSGPAPPQPETLVSTPFPWQQPIAAPSEPHRQAALHRQAQLTKPAGSLGELESLAVTLAGLQA
TNLPRIEQVCIAVFAADHGVCEEGISAFPQAVTGQMIANFVAGGAAISVMAKQLGAALEVINLGTVSPLPIDDGVIDEHI
APGTGNLARQPAMTDDQLQAALAAGDRAAQRAADRQADVFIGGEMGIGNTTSATALACALLGEDATALTGPGTGLTPEGV
AHKAQVIAQALARHGTRPEPLAVLASLGGFEIVALAGAFIGCAVRGIPVLVDGFIVSTAALAACQLRPQLRPWLLFAHQS
REPGHQRLLHALDATPLLDLSLRLGEGSGAAVAVPLLRNACALHNHMATFADANVSNEN
>Mature_378_residues
AGSVLDTPGCGAEDLPLSGPAPPQPETLVSTPFPWQQPIAAPSEPHRQAALHRQAQLTKPAGSLGELESLAVTLAGLQAT
NLPRIEQVCIAVFAADHGVCEEGISAFPQAVTGQMIANFVAGGAAISVMAKQLGAALEVINLGTVSPLPIDDGVIDEHIA
PGTGNLARQPAMTDDQLQAALAAGDRAAQRAADRQADVFIGGEMGIGNTTSATALACALLGEDATALTGPGTGLTPEGVA
HKAQVIAQALARHGTRPEPLAVLASLGGFEIVALAGAFIGCAVRGIPVLVDGFIVSTAALAACQLRPQLRPWLLFAHQSR
EPGHQRLLHALDATPLLDLSLRLGEGSGAAVAVPLLRNACALHNHMATFADANVSNEN

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=322, Percent_Identity=39.7515527950311, Blast_Score=222, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 38634; Mature: 38503

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSVLDTPGCGAEDLPLSGPAPPQPETLVSTPFPWQQPIAAPSEPHRQAALHRQAQLTK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PAGSLGELESLAVTLAGLQATNLPRIEQVCIAVFAADHGVCEEGISAFPQAVTGQMIANF
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VAGGAAISVMAKQLGAALEVINLGTVSPLPIDDGVIDEHIAPGTGNLARQPAMTDDQLQA
HHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHH
ALAAGDRAAQRAADRQADVFIGGEMGIGNTTSATALACALLGEDATALTGPGTGLTPEGV
HHHHCHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCHHH
AHKAQVIAQALARHGTRPEPLAVLASLGGFEIVALAGAFIGCAVRGIPVLVDGFIVSTAA
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LAACQLRPQLRPWLLFAHQSREPGHQRLLHALDATPLLDLSLRLGEGSGAAVAVPLLRNA
HHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEHHHHHHH
CALHNHMATFADANVSNEN
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AGSVLDTPGCGAEDLPLSGPAPPQPETLVSTPFPWQQPIAAPSEPHRQAALHRQAQLTK
CCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PAGSLGELESLAVTLAGLQATNLPRIEQVCIAVFAADHGVCEEGISAFPQAVTGQMIANF
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VAGGAAISVMAKQLGAALEVINLGTVSPLPIDDGVIDEHIAPGTGNLARQPAMTDDQLQA
HHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHH
ALAAGDRAAQRAADRQADVFIGGEMGIGNTTSATALACALLGEDATALTGPGTGLTPEGV
HHHHCHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCHHH
AHKAQVIAQALARHGTRPEPLAVLASLGGFEIVALAGAFIGCAVRGIPVLVDGFIVSTAA
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LAACQLRPQLRPWLLFAHQSREPGHQRLLHALDATPLLDLSLRLGEGSGAAVAVPLLRNA
HHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEHHHHHHH
CALHNHMATFADANVSNEN
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA