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The map label for this gene is cobC [H]

Identifier: 110835240

GI number: 110835240

Start: 2704030

End: 2704626

Strand: Direct

Name: cobC [H]

Synonym: ABO_2379

Alternate gene names: 110835240

Gene position: 2704030-2704626 (Clockwise)

Preceding gene: 110835239

Following gene: 110835245

Centisome position: 86.66

GC content: 57.12

Gene sequence:

>597_bases
ATGAGCACCACTATTTTTGACCTGATTCGTCATGGTGAACCCGCCGGCGGGCAAATGTACCGGGGCCACAAAGATGACCC
GCTAAGCGAGCAGGGCTGGCAGCAAATGCGTAATGCCATTACCGGCGACGATCAGTGGGACCACATCCTCAGCTCGCCCC
TATTACGTTGCCGGGAATTTGCCGCCGAGCTGGCCAAGGAAAAGAATTTGCCGATGACCGTAGCGCACGATTTTAAAGAA
ATCAGCTTCGGCGACTGGGAAGGAAAAACCCGCGAGCAGGTGGCCCAGGAATACGGCGATCACCAAGCCAACTTCTGGCG
CGATGCAGAAAGCCACCCACCGAGCAATGCGGAAACTATTCAGGATTTTCATCAACGCATCGGTGAAGCCTGGGCGCTGT
GGCAAAACACATTGAAGGGCCAGCGGGTGCTATTGGTGTGCCACGGCGGCGTCATTCGCATGGTGCTAAGCCACGTACTC
AGCATAGCCCCCAGCAAAGCCATGGCCGGCTTTCAGGTGCCTTACGCCTGCCGCTCACGGGTGCGGCTAGATGCCAGCGA
ATTCGGCACCTTGAGTTGCTTGATACGGCACGGGTAA

Upstream 100 bases:

>100_bases
ATATGGCGACCTTTGCCGACGCCAATGTCAGCAACGAAAACTAATTTTGCCGGATTACAGTAACGCCGAAGCCAACCTAC
AAGAACGGGAATAGATACCG

Downstream 100 bases:

>100_bases
TTCTGGGTTGAACCTTCCACGTTGAAACGCGGGTAAGCCCCGGCTAACTGAGCGTTTTAGTCGCGACCTTTGAGGTGTAT
GTGATGAGGTGTATTTGTGA

Product: alpha-ribazole-5'-phosphate phosphatase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSTTIFDLIRHGEPAGGQMYRGHKDDPLSEQGWQQMRNAITGDDQWDHILSSPLLRCREFAAELAKEKNLPMTVAHDFKE
ISFGDWEGKTREQVAQEYGDHQANFWRDAESHPPSNAETIQDFHQRIGEAWALWQNTLKGQRVLLVCHGGVIRMVLSHVL
SIAPSKAMAGFQVPYACRSRVRLDASEFGTLSCLIRHG

Sequences:

>Translated_198_residues
MSTTIFDLIRHGEPAGGQMYRGHKDDPLSEQGWQQMRNAITGDDQWDHILSSPLLRCREFAAELAKEKNLPMTVAHDFKE
ISFGDWEGKTREQVAQEYGDHQANFWRDAESHPPSNAETIQDFHQRIGEAWALWQNTLKGQRVLLVCHGGVIRMVLSHVL
SIAPSKAMAGFQVPYACRSRVRLDASEFGTLSCLIRHG
>Mature_197_residues
STTIFDLIRHGEPAGGQMYRGHKDDPLSEQGWQQMRNAITGDDQWDHILSSPLLRCREFAAELAKEKNLPMTVAHDFKEI
SFGDWEGKTREQVAQEYGDHQANFWRDAESHPPSNAETIQDFHQRIGEAWALWQNTLKGQRVLLVCHGGVIRMVLSHVLS
IAPSKAMAGFQVPYACRSRVRLDASEFGTLSCLIRHG

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=191, Percent_Identity=29.3193717277487, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 22427; Mature: 22295

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTIFDLIRHGEPAGGQMYRGHKDDPLSEQGWQQMRNAITGDDQWDHILSSPLLRCREF
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AAELAKEKNLPMTVAHDFKEISFGDWEGKTREQVAQEYGDHQANFWRDAESHPPSNAETI
HHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHH
QDFHQRIGEAWALWQNTLKGQRVLLVCHGGVIRMVLSHVLSIAPSKAMAGFQVPYACRSR
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHH
VRLDASEFGTLSCLIRHG
HCCCHHHHHHHHHHEECC
>Mature Secondary Structure 
STTIFDLIRHGEPAGGQMYRGHKDDPLSEQGWQQMRNAITGDDQWDHILSSPLLRCREF
CHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AAELAKEKNLPMTVAHDFKEISFGDWEGKTREQVAQEYGDHQANFWRDAESHPPSNAETI
HHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHH
QDFHQRIGEAWALWQNTLKGQRVLLVCHGGVIRMVLSHVLSIAPSKAMAGFQVPYACRSR
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHH
VRLDASEFGTLSCLIRHG
HCCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]