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The map label for this gene is ggpS [H]

Identifier: 110835026

GI number: 110835026

Start: 2473984

End: 2474892

Strand: Direct

Name: ggpS [H]

Synonym: ABO_2165

Alternate gene names: 110835026

Gene position: 2473984-2474892 (Clockwise)

Preceding gene: 110835025

Following gene: 110835027

Centisome position: 79.29

GC content: 57.54

Gene sequence:

>909_bases
ATGAGCAGTAAGGCAACACGCGAATTCGCCGCCCTGAACCAACTCACGGATACCGCCAAGGCTCGTCTGGAGCAGGCGCT
GGACCATTACTTGCCGGCCCATAGTGCCGCCTCACGGCTCAGCCATGCCATGCGCTATGCAGCACTCAGCGGCGGCAAAC
GTATCCGCCCGTTACTAGTATACGGCGCCGCCCAGCTTGCCGGGGCTCCCCTAGCCAAAGCAGATGTCCCCGCGGTGGCA
GTAGAACTCATTCACGCCTACTCCCTGGTTCACGACGACCTTCCCGCCATGGACGACGATGACCTTCGCCGGGGCCAACC
TACCTGCCACAAAGCCTTTGACGAAGCGACCGCCATTCTTGCCGGTGACACCCTGCATACCCGCGCGTTTGAACTGCTCG
CCTGTCATGGCGACTACCGCGATGGCAGCCGCATCAGCTTGATTCAACACCTTTGCCAAGCTGCCGGGGTAGATGGAATG
GCCGCTGGGCAAATGCAAGATATGCTCGCCCAAGGGCAACAGCAAACCGTGGCCGCGTTGGAAGAAATGCATTACCTGAA
AACTGGCCGGCTAATCACCGCCAGCTTACAACTAGGTTATTTTGTCGCAGAAAAAGACGACCCTTCGCTACTAGCCAATC
TAACCGAATTTGGCGACGCCATTGGCCTGGCCTTTCAGATACAGGACGATATCCTCGACGTCACCGCCGCTACCGAGCAA
CTTGGCAAGCCCTCAGGTTCTGATGAAAAGCTGCAAAAAAGCACCTTCCCATCCCTTCTCGGTCTGGAGCAAAGTCAGCA
ACGTGCTCGCCAACTCTGCGATCAAGCACAACAAACCTTGGCCGGCTATGGGCCGCGGGCACTTCCTTTACAGCAACTCG
CCCAGTACATCATTACCCGGAATCATTGA

Upstream 100 bases:

>100_bases
CGGGAATGCCAACAAGCCCTGCAACAAGCGGAACAAAAAGTACGCATCCTGCTGGAACAGAACACCGAGGCAGACCCTGA
GCCCTTTATCGGTGGTGACA

Downstream 100 bases:

>100_bases
TCAACACTGACGCCTACCCCTCCAGACAGTTATACTAGCGGTTCGAGCGAGACCCTGGACGCTTTTGTTATACAGCGTTT
CGCTGACTCATTACTCTGCC

Product: geranylgeranyl pyrophosphate synthetase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSSKATREFAALNQLTDTAKARLEQALDHYLPAHSAASRLSHAMRYAALSGGKRIRPLLVYGAAQLAGAPLAKADVPAVA
VELIHAYSLVHDDLPAMDDDDLRRGQPTCHKAFDEATAILAGDTLHTRAFELLACHGDYRDGSRISLIQHLCQAAGVDGM
AAGQMQDMLAQGQQQTVAALEEMHYLKTGRLITASLQLGYFVAEKDDPSLLANLTEFGDAIGLAFQIQDDILDVTAATEQ
LGKPSGSDEKLQKSTFPSLLGLEQSQQRARQLCDQAQQTLAGYGPRALPLQQLAQYIITRNH

Sequences:

>Translated_302_residues
MSSKATREFAALNQLTDTAKARLEQALDHYLPAHSAASRLSHAMRYAALSGGKRIRPLLVYGAAQLAGAPLAKADVPAVA
VELIHAYSLVHDDLPAMDDDDLRRGQPTCHKAFDEATAILAGDTLHTRAFELLACHGDYRDGSRISLIQHLCQAAGVDGM
AAGQMQDMLAQGQQQTVAALEEMHYLKTGRLITASLQLGYFVAEKDDPSLLANLTEFGDAIGLAFQIQDDILDVTAATEQ
LGKPSGSDEKLQKSTFPSLLGLEQSQQRARQLCDQAQQTLAGYGPRALPLQQLAQYIITRNH
>Mature_301_residues
SSKATREFAALNQLTDTAKARLEQALDHYLPAHSAASRLSHAMRYAALSGGKRIRPLLVYGAAQLAGAPLAKADVPAVAV
ELIHAYSLVHDDLPAMDDDDLRRGQPTCHKAFDEATAILAGDTLHTRAFELLACHGDYRDGSRISLIQHLCQAAGVDGMA
AGQMQDMLAQGQQQTVAALEEMHYLKTGRLITASLQLGYFVAEKDDPSLLANLTEFGDAIGLAFQIQDDILDVTAATEQL
GKPSGSDEKLQKSTFPSLLGLEQSQQRARQLCDQAQQTLAGYGPRALPLQQLAQYIITRNH

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=237, Percent_Identity=31.2236286919831, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1786623, Length=284, Percent_Identity=49.2957746478873, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1789578, Length=215, Percent_Identity=34.4186046511628, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17505681, Length=187, Percent_Identity=30.4812834224599, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24651612, Length=187, Percent_Identity=32.620320855615, Blast_Score=88, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 32643; Mature: 32512

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKATREFAALNQLTDTAKARLEQALDHYLPAHSAASRLSHAMRYAALSGGKRIRPLLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHE
YGAAQLAGAPLAKADVPAVAVELIHAYSLVHDDLPAMDDDDLRRGQPTCHKAFDEATAIL
ECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHH
AGDTLHTRAFELLACHGDYRDGSRISLIQHLCQAAGVDGMAAGQMQDMLAQGQQQTVAAL
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
EEMHYLKTGRLITASLQLGYFVAEKDDPSLLANLTEFGDAIGLAFQIQDDILDVTAATEQ
HHHHHHHHCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHH
LGKPSGSDEKLQKSTFPSLLGLEQSQQRARQLCDQAQQTLAGYGPRALPLQQLAQYIITR
HCCCCCCHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NH
CC
>Mature Secondary Structure 
SSKATREFAALNQLTDTAKARLEQALDHYLPAHSAASRLSHAMRYAALSGGKRIRPLLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHE
YGAAQLAGAPLAKADVPAVAVELIHAYSLVHDDLPAMDDDDLRRGQPTCHKAFDEATAIL
ECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHH
AGDTLHTRAFELLACHGDYRDGSRISLIQHLCQAAGVDGMAAGQMQDMLAQGQQQTVAAL
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
EEMHYLKTGRLITASLQLGYFVAEKDDPSLLANLTEFGDAIGLAFQIQDDILDVTAATEQ
HHHHHHHHCCEEEEEEECCEEEECCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHH
LGKPSGSDEKLQKSTFPSLLGLEQSQQRARQLCDQAQQTLAGYGPRALPLQQLAQYIITR
HCCCCCCHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
NH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]