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The map label for this gene is bah [H]

Identifier: 110834969

GI number: 110834969

Start: 2414685

End: 2415635

Strand: Direct

Name: bah [H]

Synonym: ABO_2108

Alternate gene names: 110834969

Gene position: 2414685-2415635 (Clockwise)

Preceding gene: 110834968

Following gene: 110834970

Centisome position: 77.39

GC content: 56.99

Gene sequence:

>951_bases
ATGAGCCTGTTTGTTGATCGCATCAGCCGTAGCCAGTCGACACTGCAACAAGTACTGGCAGGCACGCTACGCCAATCCCT
GGCACTACTATTCAAACCCGTTGCCAATCCACGCTTCAGCTTTACTGCACAGCGGCGCTGGCTAGACATTATGGCCCACA
GTACCCTCAAAGCCCGAGGCATCGGCAGCCACGATAACGCGTTAGCCAATGTACCTTGCCGCCACTACCAGCCGTTGCAT
GCACAAACTACCGTGCTCTATTTACATGGCGGTGGTTACGTGGCTGGGAGTCCGGACAGCCACAAGTCCATTACCTCGCA
CCTAGCCAAATTCGCCAATGCCCATGTGGTGGTGCCGGATTACCGGCTCGCTCCGGAACACCCCTGCCCTGCCGCCATCG
AAGACGCCGTCGCGGTCTACCTAGCTCTGCTAGAGAGCGGCGTAAGCCCCGGCTCTCTAACGTTGATGGGCGACTCCGCT
GGAGGCGGATTAGCACTGGCCACGCTGCAAGCGTTAAAAGCCAGCGGTAAGCCGCTACCCAGCAGCGTTATTCTTTTTTC
CCCCTGGGTTGACCTAACCTTGGGACAGCTTTACGACACCGACCGAGATATCATGCTAAGCCATAGCTGGCTAGCCAGCG
CGGCTGACGCCTATGCGGGTAATGATACCCGCAATGTCCAGTGCTCCCCGCTGTTCGGCGAACTAAGTGACTTGCCCCCC
ACGCTAATCCAAGCCGGCGGCGATGAAATTCTGCTTAATGATAGCCACCGTCTGTGCGCTGCTTTAAACGAAGCGGGCAC
CCCAACACGGCTACAGATTCACCCGCAACGCTGGCACGATTTTCAATTACACGCGGGTGTACTTGCAGACTCGGATCACG
CTCTGATGACCTGCGCACGCTTTATTCACCAACATGCCATCCATGACCATGAAGAGGACGCTCACGCATGA

Upstream 100 bases:

>100_bases
CCGATAGTGGTAAGAACACCAACAACTGGCCCGGTTTCACTTTTGACTACCGCCGCCAAACCCAACACTTGCAACTCAAC
GACTACGAGTACAAATCCCT

Downstream 100 bases:

>100_bases
AACGCATCATGATTACTGGCGCAGCTAGCGGCATTGGGTTGGCCACCGCCACCTTCTTCCATAACAAGGGCTGGCAGGTG
GGCCTTACCGACATCAATGA

Product: lipase/esterase

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSLFVDRISRSQSTLQQVLAGTLRQSLALLFKPVANPRFSFTAQRRWLDIMAHSTLKARGIGSHDNALANVPCRHYQPLH
AQTTVLYLHGGGYVAGSPDSHKSITSHLAKFANAHVVVPDYRLAPEHPCPAAIEDAVAVYLALLESGVSPGSLTLMGDSA
GGGLALATLQALKASGKPLPSSVILFSPWVDLTLGQLYDTDRDIMLSHSWLASAADAYAGNDTRNVQCSPLFGELSDLPP
TLIQAGGDEILLNDSHRLCAALNEAGTPTRLQIHPQRWHDFQLHAGVLADSDHALMTCARFIHQHAIHDHEEDAHA

Sequences:

>Translated_316_residues
MSLFVDRISRSQSTLQQVLAGTLRQSLALLFKPVANPRFSFTAQRRWLDIMAHSTLKARGIGSHDNALANVPCRHYQPLH
AQTTVLYLHGGGYVAGSPDSHKSITSHLAKFANAHVVVPDYRLAPEHPCPAAIEDAVAVYLALLESGVSPGSLTLMGDSA
GGGLALATLQALKASGKPLPSSVILFSPWVDLTLGQLYDTDRDIMLSHSWLASAADAYAGNDTRNVQCSPLFGELSDLPP
TLIQAGGDEILLNDSHRLCAALNEAGTPTRLQIHPQRWHDFQLHAGVLADSDHALMTCARFIHQHAIHDHEEDAHA
>Mature_315_residues
SLFVDRISRSQSTLQQVLAGTLRQSLALLFKPVANPRFSFTAQRRWLDIMAHSTLKARGIGSHDNALANVPCRHYQPLHA
QTTVLYLHGGGYVAGSPDSHKSITSHLAKFANAHVVVPDYRLAPEHPCPAAIEDAVAVYLALLESGVSPGSLTLMGDSAG
GGLALATLQALKASGKPLPSSVILFSPWVDLTLGQLYDTDRDIMLSHSWLASAADAYAGNDTRNVQCSPLFGELSDLPPT
LIQAGGDEILLNDSHRLCAALNEAGTPTRLQIHPQRWHDFQLHAGVLADSDHALMTCARFIHQHAIHDHEEDAHA

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI206597554, Length=125, Percent_Identity=37.6, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786682, Length=237, Percent_Identity=29.535864978903, Blast_Score=78, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI72001146, Length=197, Percent_Identity=31.4720812182741, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533410, Length=112, Percent_Identity=33.9285714285714, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115533412, Length=112, Percent_Identity=33.9285714285714, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 34109; Mature: 33978

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS01173 LIPASE_GDXG_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFVDRISRSQSTLQQVLAGTLRQSLALLFKPVANPRFSFTAQRRWLDIMAHSTLKARG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCC
IGSHDNALANVPCRHYQPLHAQTTVLYLHGGGYVAGSPDSHKSITSHLAKFANAHVVVPD
CCCCCCCEECCCHHHCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHHHHHCCEEECCC
YRLAPEHPCPAAIEDAVAVYLALLESGVSPGSLTLMGDSAGGGLALATLQALKASGKPLP
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC
SSVILFSPWVDLTLGQLYDTDRDIMLSHSWLASAADAYAGNDTRNVQCSPLFGELSDLPP
CCEEEECCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCCCEEECCCHHCHHCCCH
TLIQAGGDEILLNDSHRLCAALNEAGTPTRLQIHPQRWHDFQLHAGVLADSDHALMTCAR
HHHHCCCCEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCEEEECCEEECCCHHHHHHHH
FIHQHAIHDHEEDAHA
HHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLFVDRISRSQSTLQQVLAGTLRQSLALLFKPVANPRFSFTAQRRWLDIMAHSTLKARG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCC
IGSHDNALANVPCRHYQPLHAQTTVLYLHGGGYVAGSPDSHKSITSHLAKFANAHVVVPD
CCCCCCCEECCCHHHCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHHHHHCCEEECCC
YRLAPEHPCPAAIEDAVAVYLALLESGVSPGSLTLMGDSAGGGLALATLQALKASGKPLP
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC
SSVILFSPWVDLTLGQLYDTDRDIMLSHSWLASAADAYAGNDTRNVQCSPLFGELSDLPP
CCEEEECCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCCCEEECCCHHCHHCCCH
TLIQAGGDEILLNDSHRLCAALNEAGTPTRLQIHPQRWHDFQLHAGVLADSDHALMTCAR
HHHHCCCCEEEEECCHHHHHHHHCCCCCCEEEECCCCCCCEEEECCEEECCCHHHHHHHH
FIHQHAIHDHEEDAHA
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]