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The map label for this gene is ucpA [H]

Identifier: 110834970

GI number: 110834970

Start: 2415632

End: 2416390

Strand: Direct

Name: ucpA [H]

Synonym: ABO_2109

Alternate gene names: 110834970

Gene position: 2415632-2416390 (Clockwise)

Preceding gene: 110834969

Following gene: 110834972

Centisome position: 77.42

GC content: 54.02

Gene sequence:

>759_bases
ATGAAACGCATCATGATTACTGGCGCAGCTAGCGGCATTGGGTTGGCCACCGCCACCTTCTTCCATAACAAGGGCTGGCA
GGTGGGCCTTACCGACATCAATGAAACCGCCCTAGCCAAGCTCGCCAGAGAACTGAATGGCAGCTGGTATCAGCGTCTGG
ATGTAACCGAAGCAACCGCCTGCCAGAAAGCCTGCGAGAGCTTTTCTCAAGGCAAGGGCTTTGATGTGCTCTTCAACTGC
GCAGGGGTTTTGCGCATGGGGCATTTCGAAGACATCAGTGCCGAGCAGCATAAACAAATCATTGATATCAATGTGATGGG
GTTGATCAACATGACCTTGGCGGCTCAACCCCATCTACAACTGAGCACTGAGCCCGTAGTGATAAACATGAGTTCCGCCT
CTGCGCTCTACGGGGTGCCGCATCTAGCGTCCTACTCCGCCAGCAAATTTGCCGTGCGAGCACTCACCGAAGCCCTCAAT
ATCGAATGGGCACGCCAGGGTATTCGCGTGGTGGATATCATGCCCCCCTTTGTGAAGACCCCGATGATCGACGGGGCCAT
TTTCCGCGCCCCGGTAGTGGACCGCTTGGGCGTCAATCTCACCGCCGAAGACATCGCCGCTAAAGCCTGGCAAGCCGCAA
ATGAAAACGTGCCGGTTCACAATCCTGTAGGCCGCACATTTAAGTTAATTAAGTTGATGGACAAGGTATTGCCCAGTGTT
TCCACCAAGCTGACCATGACATTTCTTAGCCGCGAATAA

Upstream 100 bases:

>100_bases
TACACGCGGGTGTACTTGCAGACTCGGATCACGCTCTGATGACCTGCGCACGCTTTATTCACCAACATGCCATCCATGAC
CATGAAGAGGACGCTCACGC

Downstream 100 bases:

>100_bases
AAACGTCGTAAGCGTTAAGCTGCCGCACGACGGAAAAGATAATAAGGATTAAAAATAAAGGAGCCATGGCCAAGGTCTGG
CCTCGGCTCCTGTGCATTGA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKRIMITGAASGIGLATATFFHNKGWQVGLTDINETALAKLARELNGSWYQRLDVTEATACQKACESFSQGKGFDVLFNC
AGVLRMGHFEDISAEQHKQIIDINVMGLINMTLAAQPHLQLSTEPVVINMSSASALYGVPHLASYSASKFAVRALTEALN
IEWARQGIRVVDIMPPFVKTPMIDGAIFRAPVVDRLGVNLTAEDIAAKAWQAANENVPVHNPVGRTFKLIKLMDKVLPSV
STKLTMTFLSRE

Sequences:

>Translated_252_residues
MKRIMITGAASGIGLATATFFHNKGWQVGLTDINETALAKLARELNGSWYQRLDVTEATACQKACESFSQGKGFDVLFNC
AGVLRMGHFEDISAEQHKQIIDINVMGLINMTLAAQPHLQLSTEPVVINMSSASALYGVPHLASYSASKFAVRALTEALN
IEWARQGIRVVDIMPPFVKTPMIDGAIFRAPVVDRLGVNLTAEDIAAKAWQAANENVPVHNPVGRTFKLIKLMDKVLPSV
STKLTMTFLSRE
>Mature_252_residues
MKRIMITGAASGIGLATATFFHNKGWQVGLTDINETALAKLARELNGSWYQRLDVTEATACQKACESFSQGKGFDVLFNC
AGVLRMGHFEDISAEQHKQIIDINVMGLINMTLAAQPHLQLSTEPVVINMSSASALYGVPHLASYSASKFAVRALTEALN
IEWARQGIRVVDIMPPFVKTPMIDGAIFRAPVVDRLGVNLTAEDIAAKAWQAANENVPVHNPVGRTFKLIKLMDKVLPSV
STKLTMTFLSRE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=252, Percent_Identity=28.1746031746032, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4758504, Length=196, Percent_Identity=31.1224489795918, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI15277342, Length=196, Percent_Identity=29.5918367346939, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=182, Percent_Identity=35.7142857142857, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40807363, Length=197, Percent_Identity=27.9187817258883, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI59889578, Length=169, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI44680136, Length=184, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI44680133, Length=184, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI17738292, Length=184, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=187, Percent_Identity=35.2941176470588, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790717, Length=186, Percent_Identity=32.258064516129, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1786812, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=225, Percent_Identity=27.5555555555556, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788459, Length=185, Percent_Identity=28.1081081081081, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=185, Percent_Identity=33.5135135135135, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=189, Percent_Identity=31.7460317460317, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=27.3684210526316, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=187, Percent_Identity=26.7379679144385, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=194, Percent_Identity=30.4123711340206, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=178, Percent_Identity=28.0898876404494, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=32.1052631578947, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=26.2032085561497, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI23397609, Length=183, Percent_Identity=34.4262295081967, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644339, Length=187, Percent_Identity=30.4812834224599, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571526, Length=187, Percent_Identity=32.0855614973262, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21357041, Length=187, Percent_Identity=29.9465240641711, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737361, Length=196, Percent_Identity=31.1224489795918, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=26.8421052631579, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364892, Length=214, Percent_Identity=31.7757009345794, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24639444, Length=190, Percent_Identity=30, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27500; Mature: 27500

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIMITGAASGIGLATATFFHNKGWQVGLTDINETALAKLARELNGSWYQRLDVTEATA
CCEEEEEECCCCCCHHHEEEEECCCCEEECCCCCHHHHHHHHHHHCCCHHHHCCCHHHHH
CQKACESFSQGKGFDVLFNCAGVLRMGHFEDISAEQHKQIIDINVMGLINMTLAAQPHLQ
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHCCEEEEEEEEEEEEHEEECCCCCE
LSTEPVVINMSSASALYGVPHLASYSASKFAVRALTEALNIEWARQGIRVVDIMPPFVKT
ECCCCEEEEECCCCHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHC
PMIDGAIFRAPVVDRLGVNLTAEDIAAKAWQAANENVPVHNPVGRTFKLIKLMDKVLPSV
CCCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCH
STKLTMTFLSRE
HHHEEEEEECCC
>Mature Secondary Structure
MKRIMITGAASGIGLATATFFHNKGWQVGLTDINETALAKLARELNGSWYQRLDVTEATA
CCEEEEEECCCCCCHHHEEEEECCCCEEECCCCCHHHHHHHHHHHCCCHHHHCCCHHHHH
CQKACESFSQGKGFDVLFNCAGVLRMGHFEDISAEQHKQIIDINVMGLINMTLAAQPHLQ
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHCCEEEEEEEEEEEEHEEECCCCCE
LSTEPVVINMSSASALYGVPHLASYSASKFAVRALTEALNIEWARQGIRVVDIMPPFVKT
ECCCCEEEEECCCCHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHC
PMIDGAIFRAPVVDRLGVNLTAEDIAAKAWQAANENVPVHNPVGRTFKLIKLMDKVLPSV
CCCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCH
STKLTMTFLSRE
HHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]