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The map label for this gene is ctaC [H]

Identifier: 110633098

GI number: 110633098

Start: 817213

End: 818076

Strand: Direct

Name: ctaC [H]

Synonym: Meso_0741

Alternate gene names: 110633098

Gene position: 817213-818076 (Clockwise)

Preceding gene: 110633094

Following gene: 110633099

Centisome position: 18.52

GC content: 60.65

Gene sequence:

>864_bases
ATGAAGAAATTTGCAGCAGGCGTTGGGGCTCTGTCGCTTTCCGCGAGCGGTGCTTTCGCCGCACAGCCGCAGCCTTGGGA
AATGCGCTTCCAGAGTGCCGCGACGGAAATTATGCGGGAAATCACCTGGTTTGAGGAATACACGCTCTGGTTTGTCGGCC
CGATCGTGCTCCTCGTGATGGCGCTGCTGGCTTGGTGTATCTTCCGCTACCGCGCGAGCGCCAATCCGGTGCCCTCGCGC
ACCAGCCACAATACGCTGATCGAGGTGCTGTGGACCGTCGGACCCGTGGTGGTGCTCCTGTTCCTTGCGATTCCTTCCTT
CCAGCTCCTGACCCATCAGTACACGCCCGATGAGGAACCCACGCTGACGGTGAAGGCGACGGGCGTGCAGTGGTACTGGG
ATTATGAATACCAGGATGCGGAAAACCCGCTCAGCTTCACCTCGCTTTTGCTGCAGGATGGTGACCGTGCAGGCGCCGGC
AAGGAAAATGTGGCGCAGTATCCGCGCCTTCTTGCGGTCGACAACGAGGTTGTTGTGCCGGTCAACACGACGGTGCGCCT
GCTGGTGACGGCGAGCGACGTCATCCACGCTTTCGCCATGCCCTCCTTCGGCATAAAGGTCGACGCCGTTCCGGGGCGCA
TCAATGAGACCTGGTTCAAGGCTGAGCGAGAGGGGCTTTACTACGGTCAGTGCTCGGAGCTTTGCGGCAAGGACCACGCA
TTCATGCCGATTGCCATTCGCGTCGTGTCGCAGGAACAGTACCAGACCTGGTATGCCGCCGCGCAGCAGGATCTTACCGG
CGCCAATCGCGCTTTGATGGCGGCAATCGAAAACGGCAAGGACAAGATCGCCGCCGCCCAGTAG

Upstream 100 bases:

>100_bases
GAGCCAGGAATCTCAACAGGGCTTTCCGGGGGCGCTGCATTTTGCCATAGCGCAATCGAGCAGCCGCGGTAGGCGGGTTG
ATCGGGAGATGACGAGGGTG

Downstream 100 bases:

>100_bases
CGGCAGAGCGACCAAAGGATAATGGAGCGGTAGGATATGGCAGGCGCTGCAGCGATTAGCGACCACGACGACCACAAGCC
GAGAGGCTGGGTCCGCTGGG

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKKFAAGVGALSLSASGAFAAQPQPWEMRFQSAATEIMREITWFEEYTLWFVGPIVLLVMALLAWCIFRYRASANPVPSR
TSHNTLIEVLWTVGPVVVLLFLAIPSFQLLTHQYTPDEEPTLTVKATGVQWYWDYEYQDAENPLSFTSLLLQDGDRAGAG
KENVAQYPRLLAVDNEVVVPVNTTVRLLVTASDVIHAFAMPSFGIKVDAVPGRINETWFKAEREGLYYGQCSELCGKDHA
FMPIAIRVVSQEQYQTWYAAAQQDLTGANRALMAAIENGKDKIAAAQ

Sequences:

>Translated_287_residues
MKKFAAGVGALSLSASGAFAAQPQPWEMRFQSAATEIMREITWFEEYTLWFVGPIVLLVMALLAWCIFRYRASANPVPSR
TSHNTLIEVLWTVGPVVVLLFLAIPSFQLLTHQYTPDEEPTLTVKATGVQWYWDYEYQDAENPLSFTSLLLQDGDRAGAG
KENVAQYPRLLAVDNEVVVPVNTTVRLLVTASDVIHAFAMPSFGIKVDAVPGRINETWFKAEREGLYYGQCSELCGKDHA
FMPIAIRVVSQEQYQTWYAAAQQDLTGANRALMAAIENGKDKIAAAQ
>Mature_287_residues
MKKFAAGVGALSLSASGAFAAQPQPWEMRFQSAATEIMREITWFEEYTLWFVGPIVLLVMALLAWCIFRYRASANPVPSR
TSHNTLIEVLWTVGPVVVLLFLAIPSFQLLTHQYTPDEEPTLTVKATGVQWYWDYEYQDAENPLSFTSLLLQDGDRAGAG
KENVAQYPRLLAVDNEVVVPVNTTVRLLVTASDVIHAFAMPSFGIKVDAVPGRINETWFKAEREGLYYGQCSELCGKDHA
FMPIAIRVVSQEQYQTWYAAAQQDLTGANRALMAAIENGKDKIAAAQ

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=235, Percent_Identity=34.8936170212766, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6226540, Length=244, Percent_Identity=41.3934426229508, Blast_Score=176, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31917; Mature: 31917

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFAAGVGALSLSASGAFAAQPQPWEMRFQSAATEIMREITWFEEYTLWFVGPIVLLVM
CCCHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLAWCIFRYRASANPVPSRTSHNTLIEVLWTVGPVVVLLFLAIPSFQLLTHQYTPDEEP
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCC
TLTVKATGVQWYWDYEYQDAENPLSFTSLLLQDGDRAGAGKENVAQYPRLLAVDNEVVVP
EEEEEECCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCEEEEECCCEEEE
VNTTVRLLVTASDVIHAFAMPSFGIKVDAVPGRINETWFKAEREGLYYGQCSELCGKDHA
CCCEEEEEEEHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCEECCHHHHCCCCCC
FMPIAIRVVSQEQYQTWYAAAQQDLTGANRALMAAIENGKDKIAAAQ
EEEEEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKFAAGVGALSLSASGAFAAQPQPWEMRFQSAATEIMREITWFEEYTLWFVGPIVLLVM
CCCHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLAWCIFRYRASANPVPSRTSHNTLIEVLWTVGPVVVLLFLAIPSFQLLTHQYTPDEEP
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCCC
TLTVKATGVQWYWDYEYQDAENPLSFTSLLLQDGDRAGAGKENVAQYPRLLAVDNEVVVP
EEEEEECCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCEEEEECCCEEEE
VNTTVRLLVTASDVIHAFAMPSFGIKVDAVPGRINETWFKAEREGLYYGQCSELCGKDHA
CCCEEEEEEEHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCEECCHHHHCCCCCC
FMPIAIRVVSQEQYQTWYAAAQQDLTGANRALMAAIENGKDKIAAAQ
EEEEEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA