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The map label for this gene is htpX [H]

Identifier: 109947623

GI number: 109947623

Start: 942393

End: 943322

Strand: Reverse

Name: htpX [H]

Synonym: Hac_1088

Alternate gene names: 109947623

Gene position: 943322-942393 (Counterclockwise)

Preceding gene: 109947624

Following gene: 109947622

Centisome position: 60.71

GC content: 36.13

Gene sequence:

>930_bases
ATGAATTTTGAAAAGATTATCGCACAAAACAAGCTCAAAACGAATGCGGTTTTAACCACTTATTGCGTGATTTTTGCTTT
TATTGGGTTGTTAGTGGATGTTATTAGAATCAACGCTAACGATTTAGGCATAGCCCTTTTTAAACTCATCACTTTTCAAA
TTTTTCCTACCATTACTGTTATCATGTTTTTAGTGGCTTTTGTCGTTATTGTTGTTTGTATTCAAAATTTTAGCTCTATC
ATGTTAAGCGGTGATGAATACAAACTTATTGATCCAAGCAAGGTTTTAAGCTCTAAAGAAAATCAAATCCACGGCCTTTT
ATTAGAGCTTTTAGAAGAAGCTAAACTTAATTTTGAACCCAAACTTTATATCATTAACGCCCCTTATATGAACGCTTTTG
CGAGCGGTTGGAATGAAACTAACTCCCTTATCGCTCTTACAAGCGCTTTAATAGAGAGGTTGGATAGAGATGAATTAAAA
GCCGTGATCGCTCATGAACTCAGCCACATAAGACACAATGACATTCGCTTGACCATGTGTGTGGGGATTTTAAGCAATAT
CATGCTGTTAGTGGCTAATTTTAGCGTGTATTTTTTCATGGGGAATCGCAAGAATAGTGGGGCGAATTTGGCAAAAATGA
TTTTATTGGTTTTACAGATTGTTTTGCCTTTTTTAACGCTCATTTTACAAATGTATTTGAGCCGCACACGAGAATACATG
GCCGATAGTGGGGCGGCATTTTTAATGCATGATAGTAAGCCCATGATTAGGGCCTTACAAAAAATTTCTAACGATTACAA
AGAAAACGATTATAAAGAAATAGACACTAATAGCACCCGATCAGCGGCTTATCTTTTTAACGCTGAAATGTTTAGCACCC
ACCCTAGCATTAAAAATCGTATCCAATCTTTATCAAGGCGCGCTCTTTAA

Upstream 100 bases:

>100_bases
AAAGAAAAAGTGCAATTTGAATTGGAATTTTACTTGCCTAAAGGGAGTTATGCGAGTGCATTGCTCAAAGAAATCAAGCA
TCAGAAAGGAGAAAATAATG

Downstream 100 bases:

>100_bases
ATGGAAAATTTTTTCAACCAATTTTTTGAAAACATCGGCGAAGATAAGAATAGAGAAGGTTTGAAAAACACGCCTAAAAG
AGTTCAAGAATTATGGAATT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNFEKIIAQNKLKTNAVLTTYCVIFAFIGLLVDVIRINANDLGIALFKLITFQIFPTITVIMFLVAFVVIVVCIQNFSSI
MLSGDEYKLIDPSKVLSSKENQIHGLLLELLEEAKLNFEPKLYIINAPYMNAFASGWNETNSLIALTSALIERLDRDELK
AVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLAKMILLVLQIVLPFLTLILQMYLSRTREYM
ADSGAAFLMHDSKPMIRALQKISNDYKENDYKEIDTNSTRSAAYLFNAEMFSTHPSIKNRIQSLSRRAL

Sequences:

>Translated_309_residues
MNFEKIIAQNKLKTNAVLTTYCVIFAFIGLLVDVIRINANDLGIALFKLITFQIFPTITVIMFLVAFVVIVVCIQNFSSI
MLSGDEYKLIDPSKVLSSKENQIHGLLLELLEEAKLNFEPKLYIINAPYMNAFASGWNETNSLIALTSALIERLDRDELK
AVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLAKMILLVLQIVLPFLTLILQMYLSRTREYM
ADSGAAFLMHDSKPMIRALQKISNDYKENDYKEIDTNSTRSAAYLFNAEMFSTHPSIKNRIQSLSRRAL
>Mature_309_residues
MNFEKIIAQNKLKTNAVLTTYCVIFAFIGLLVDVIRINANDLGIALFKLITFQIFPTITVIMFLVAFVVIVVCIQNFSSI
MLSGDEYKLIDPSKVLSSKENQIHGLLLELLEEAKLNFEPKLYIINAPYMNAFASGWNETNSLIALTSALIERLDRDELK
AVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLAKMILLVLQIVLPFLTLILQMYLSRTREYM
ADSGAAFLMHDSKPMIRALQKISNDYKENDYKEIDTNSTRSAAYLFNAEMFSTHPSIKNRIQSLSRRAL

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=201, Percent_Identity=32.8358208955224, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 35061; Mature: 35061

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFEKIIAQNKLKTNAVLTTYCVIFAFIGLLVDVIRINANDLGIALFKLITFQIFPTITV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IMFLVAFVVIVVCIQNFSSIMLSGDEYKLIDPSKVLSSKENQIHGLLLELLEEAKLNFEP
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
KLYIINAPYMNAFASGWNETNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTMC
EEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHH
VGILSNIMLLVANFSVYFFMGNRKNSGANLAKMILLVLQIVLPFLTLILQMYLSRTREYM
HHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADSGAAFLMHDSKPMIRALQKISNDYKENDYKEIDTNSTRSAAYLFNAEMFSTHPSIKNR
HCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEHHHHHCCHHHHHH
IQSLSRRAL
HHHHHHCCC
>Mature Secondary Structure
MNFEKIIAQNKLKTNAVLTTYCVIFAFIGLLVDVIRINANDLGIALFKLITFQIFPTITV
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IMFLVAFVVIVVCIQNFSSIMLSGDEYKLIDPSKVLSSKENQIHGLLLELLEEAKLNFEP
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
KLYIINAPYMNAFASGWNETNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTMC
EEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHH
VGILSNIMLLVANFSVYFFMGNRKNSGANLAKMILLVLQIVLPFLTLILQMYLSRTREYM
HHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADSGAAFLMHDSKPMIRALQKISNDYKENDYKEIDTNSTRSAAYLFNAEMFSTHPSIKNR
HCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEHHHHHCCHHHHHH
IQSLSRRAL
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]