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The map label for this gene is aroB [H]

Identifier: 109947134

GI number: 109947134

Start: 466592

End: 467623

Strand: Direct

Name: aroB [H]

Synonym: Hac_0543

Alternate gene names: 109947134

Gene position: 466592-467623 (Clockwise)

Preceding gene: 109947133

Following gene: 109947135

Centisome position: 30.03

GC content: 36.92

Gene sequence:

>1032_bases
ATGCGAGAAATTTTAATCCCTTTAAAAGAAAAAAGCTATAAAGTGTTTTTGGGGGAATTGCCCGCCATTGAATTGAAACA
AAAAGCGCTCATTGTGAGCGATAGCATTGTGGCTGGCTTGCATTTATCTTATTTATTAGAGCGCTTGAATGTATTAGAAA
CGCGCACGTGCGTGATAGAGTCTGGAGAAAAGCACAAAAACTTGAATTCTTTGGGGCGTATTTTAAACAATGCCTTTGAA
ATGCAATTAAACCGCCATTCTTTAATGATAGCCCTTGGTGGGGGAGTGATAAGCGATATGGTGGGTTTTGCGAGCAGTAT
TTATTTTAGGGGGATTGATTTTATCAATATCCCTACGACTTTACTTTCTCAAGTGGATGCGAGCGTGGGGGGGAAAACAG
GGATCAATACAGCTTATGGTAAGAATTTGATTGGATCATTCCACCAGCCTAAAGCGGTTTATATTGATTTAGCTTTTTTA
AAAACCCTTGAAAAAAGGGAATTCCAAGCAGGGGTGGCTGAAATCATTAAAATGGCGGTGTGTTTTGATAAAAGCCTGGT
AGAAGTGTTAGAAACAAAGGATTTAAAAGATTGTTTAGAAGAAGTGGTTTTTCAAAGCGTTACAATAAAAGCTCAAGTCG
TTACACAAGATGAAAAAGAGCAAAATATCAGAGCTGGGTTGAATTATGGGCATACCTTTGGGCATGCGATAGAAAAAGAG
ACTCATTATGAGCGGTTTTTGCATGGCGAAGCGATCGCTATTGGCATGTGCATGGCCAATGATTTAGCCCTTTCTTTAGG
CATGCTCACTCTAAAAGAGCATGAACGCATAGAAAATTTATTAAAAAAATTTGATTTGATATTCCATTATCAAATTTTAG
ATATTCAAAAATTTTATGAAAGTTTGTTTTTAGACAAAAAAAGCGAAAACAAGACGATCAAATTCATTCTACCTAAAGGC
ATTGGGGCGTTTGAAATAGCCGCTCATATCCCTAAAGAAACGATTTTAAAGGTGTTAGAAAAATGGCATTAA

Upstream 100 bases:

>100_bases
AAAACGCGCTTTTTGTGGTTTTTATCCACTAAAGTGGAAAAATTGGCATTTTTAAGCGACGATAACCCTCAAATTTTTAT
TCCCGTAGCGGAGTGAAGGA

Downstream 100 bases:

>100_bases
GGGTATTGTTATTCTTTTGTTTTTTGTTGTTGTGTGCAGAAGATAAAAGCCAAGAGTTATTGTCCATACAAAAACAAATG
GCTTTGGTGGATAAAAAACT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MREILIPLKEKSYKVFLGELPAIELKQKALIVSDSIVAGLHLSYLLERLNVLETRTCVIESGEKHKNLNSLGRILNNAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTTLLSQVDASVGGKTGINTAYGKNLIGSFHQPKAVYIDLAFL
KTLEKREFQAGVAEIIKMAVCFDKSLVEVLETKDLKDCLEEVVFQSVTIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
THYERFLHGEAIAIGMCMANDLALSLGMLTLKEHERIENLLKKFDLIFHYQILDIQKFYESLFLDKKSENKTIKFILPKG
IGAFEIAAHIPKETILKVLEKWH

Sequences:

>Translated_343_residues
MREILIPLKEKSYKVFLGELPAIELKQKALIVSDSIVAGLHLSYLLERLNVLETRTCVIESGEKHKNLNSLGRILNNAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTTLLSQVDASVGGKTGINTAYGKNLIGSFHQPKAVYIDLAFL
KTLEKREFQAGVAEIIKMAVCFDKSLVEVLETKDLKDCLEEVVFQSVTIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
THYERFLHGEAIAIGMCMANDLALSLGMLTLKEHERIENLLKKFDLIFHYQILDIQKFYESLFLDKKSENKTIKFILPKG
IGAFEIAAHIPKETILKVLEKWH
>Mature_343_residues
MREILIPLKEKSYKVFLGELPAIELKQKALIVSDSIVAGLHLSYLLERLNVLETRTCVIESGEKHKNLNSLGRILNNAFE
MQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTTLLSQVDASVGGKTGINTAYGKNLIGSFHQPKAVYIDLAFL
KTLEKREFQAGVAEIIKMAVCFDKSLVEVLETKDLKDCLEEVVFQSVTIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
THYERFLHGEAIAIGMCMANDLALSLGMLTLKEHERIENLLKKFDLIFHYQILDIQKFYESLFLDKKSENKTIKFILPKG
IGAFEIAAHIPKETILKVLEKWH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=359, Percent_Identity=36.4902506963788, Blast_Score=211, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6320332, Length=286, Percent_Identity=34.2657342657343, Blast_Score=172, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38652; Mature: 38652

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREILIPLKEKSYKVFLGELPAIELKQKALIVSDSIVAGLHLSYLLERLNVLETRTCVIE
CCCEEEECCCCCEEEEECCCCCHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEC
SGEKHKNLNSLGRILNNAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTT
CCCCCCCHHHHHHHHHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEECHHH
LLSQVDASVGGKTGINTAYGKNLIGSFHQPKAVYIDLAFLKTLEKREFQAGVAEIIKMAV
HHHHHHHHCCCCCCCCHHHCHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
CFDKSLVEVLETKDLKDCLEEVVFQSVTIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
HHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHH
THYERFLHGEAIAIGMCMANDLALSLGMLTLKEHERIENLLKKFDLIFHYQILDIQKFYE
HHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFLDKKSENKTIKFILPKGIGAFEIAAHIPKETILKVLEKWH
HHHCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MREILIPLKEKSYKVFLGELPAIELKQKALIVSDSIVAGLHLSYLLERLNVLETRTCVIE
CCCEEEECCCCCEEEEECCCCCHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHEEC
SGEKHKNLNSLGRILNNAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIDFINIPTT
CCCCCCCHHHHHHHHHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCEEECHHH
LLSQVDASVGGKTGINTAYGKNLIGSFHQPKAVYIDLAFLKTLEKREFQAGVAEIIKMAV
HHHHHHHHCCCCCCCCHHHCHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
CFDKSLVEVLETKDLKDCLEEVVFQSVTIKAQVVTQDEKEQNIRAGLNYGHTFGHAIEKE
HHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHH
THYERFLHGEAIAIGMCMANDLALSLGMLTLKEHERIENLLKKFDLIFHYQILDIQKFYE
HHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFLDKKSENKTIKFILPKGIGAFEIAAHIPKETILKVLEKWH
HHHCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA