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The map label for this gene is 109947135

Identifier: 109947135

GI number: 109947135

Start: 467629

End: 469170

Strand: Direct

Name: 109947135

Synonym: Hac_0544

Alternate gene names: NA

Gene position: 467629-469170 (Clockwise)

Preceding gene: 109947134

Following gene: 109947136

Centisome position: 30.09

GC content: 36.51

Gene sequence:

>1542_bases
TTGTTATTCTTTTGTTTTTTGTTGTTGTGTGCAGAAGATAAAAGCCAAGAGTTATTGTCCATACAAAAACAAATGGCTTT
GGTGGATAAAAAACTCACTAAAGATGATAATGTGTGGTTGAAGAAATTTGAAAACTATAAGATTTACAACCAAATTTATA
CTGAAAAAGAGAGCGTGAGGCAGGAATTAAGGCGCTTGAAATTCCAAAAAAATAAGGATCTCTTAAAGATTAGCACTTTA
GAGCATACCTTAAAGGCTTTAGAATCCCAACAAAAAATGTTTGAAAGCTATGGGGTCAATCCTTTTAAGGACTTGATAGA
GCGCCCCAATATCCCCAATATCCCCAATATCGCCAACCCTATTGCGATCATTGATGGCATTTCTTTCATTAAAAGCATGC
GTTTAAAGCATGAAGACCTTAAAAACAACCAGATTGCTTTAGAAGAGGTTTTGAAGCTTTTAGATGAAAAACACCAGCTT
TTAAGTCAATGGCAGGCATTGGATAAAAACGCGAAATTGAGCGATGAGATTTATCAAACTCAAGCCAAACGATTAGAATT
GCAAGGGGCTCAAAACATTTTAAAAACCACGATTGGGATCTTTCAAAAAGACAGCGATGAAGCCGTTAGCATTGTAAAAA
CCCAAATCAAAAACCAGCTTTTAAAATTGCTTTATGTGTTTTTAACCGCCCTTTTGAGCGTGGTGTTTGCGTGGATTTTA
AAAGTCATTTCCAGTAAATACATTGAAAATAACGAGCGCGTTTATACCGTTAATAAAGCCATTAACTTTGTGAATGTGAG
CGTGATTGTTTTAATCTTTCTTTTTTCTTATTTAGAAAATGTGACTTATTTAGTCACGGTTTTAGGCTTTGCGAGTGCGG
GCTTGGCGATTGCGATGAAAGACTTGTTCATGAGCTTGCTTGGGTGGTTTATTATTTTGATCGGAGGGAGTGTGCATGTG
GGCGATAGGGTGCGTATCGCTAAAGGGACTGATATTTTTATTGGCGATGTGTTGGATATTTCTATGTTGCACATTACGAT
TTTAGAAGATGTGACCTTAACCACTTATTCTAATAACAGAAGAGCGGGCCGGATTGTTTTTGTGCCTAATAATTATATTT
TCACTACCATGTTTGCCAATTACAGCCATTTTGGCATGAAAACGGTTTGGGATGGGGTGGATTTTTGCGTGACATTTGAT
TCTGATTTTAAAAAAGCTTCTAAAATTGCACTCAATATCGCGACAGAATTGTCTAAAGAATACACGGATATTACTTATAA
ACAGCTCAATAAAATGCGCGATAGGTATTCTTTAAGGAGTTTGAGCGTGAAGCCGCGATGCTTTTTGATGCCTGAAAATA
ATGGGATAAAGATTTCAGTGTGGTATCAAACCAATTCGTATGCCACTTTGTCTTTAAGGAGCAAGATTACGGCTGAAATT
ATTGAAGCTTTTTTGAAAGAAGAAAATATCCATATCGCTTATACCACCAGCAAATTGCTTAAAGTGGATACTGAGGGCGA
TGGCTTTGGGAATAAAAGGTAA

Upstream 100 bases:

>100_bases
TCAAATTCATTCTACCTAAAGGCATTGGGGCGTTTGAAATAGCCGCTCATATCCCTAAAGAAACGATTTTAAAGGTGTTA
GAAAAATGGCATTAAGGGTA

Downstream 100 bases:

>100_bases
CAAGAATGAAAAAAGTCTATTTTAAAACTTTTGGGTGCAGAACGAATCTTTTTGACACGCAAGTGATGGGCGAGAATTTA
AAGGATTTTAGCGCGACTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MLFFCFLLLCAEDKSQELLSIQKQMALVDKKLTKDDNVWLKKFENYKIYNQIYTEKESVRQELRRLKFQKNKDLLKISTL
EHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMRLKHEDLKNNQIALEEVLKLLDEKHQL
LSQWQALDKNAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAVSIVKTQIKNQLLKLLYVFLTALLSVVFAWIL
KVISSKYIENNERVYTVNKAINFVNVSVIVLIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIGGSVHV
GDRVRIAKGTDIFIGDVLDISMLHITILEDVTLTTYSNNRRAGRIVFVPNNYIFTTMFANYSHFGMKTVWDGVDFCVTFD
SDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSKITAEI
IEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKR

Sequences:

>Translated_513_residues
MLFFCFLLLCAEDKSQELLSIQKQMALVDKKLTKDDNVWLKKFENYKIYNQIYTEKESVRQELRRLKFQKNKDLLKISTL
EHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMRLKHEDLKNNQIALEEVLKLLDEKHQL
LSQWQALDKNAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAVSIVKTQIKNQLLKLLYVFLTALLSVVFAWIL
KVISSKYIENNERVYTVNKAINFVNVSVIVLIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIGGSVHV
GDRVRIAKGTDIFIGDVLDISMLHITILEDVTLTTYSNNRRAGRIVFVPNNYIFTTMFANYSHFGMKTVWDGVDFCVTFD
SDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSKITAEI
IEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKR
>Mature_513_residues
MLFFCFLLLCAEDKSQELLSIQKQMALVDKKLTKDDNVWLKKFENYKIYNQIYTEKESVRQELRRLKFQKNKDLLKISTL
EHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANPIAIIDGISFIKSMRLKHEDLKNNQIALEEVLKLLDEKHQL
LSQWQALDKNAKLSDEIYQTQAKRLELQGAQNILKTTIGIFQKDSDEAVSIVKTQIKNQLLKLLYVFLTALLSVVFAWIL
KVISSKYIENNERVYTVNKAINFVNVSVIVLIFLFSYLENVTYLVTVLGFASAGLAIAMKDLFMSLLGWFIILIGGSVHV
GDRVRIAKGTDIFIGDVLDISMLHITILEDVTLTTYSNNRRAGRIVFVPNNYIFTTMFANYSHFGMKTVWDGVDFCVTFD
SDFKKASKIALNIATELSKEYTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSKITAEI
IEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKR

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 59008; Mature: 59008

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFFCFLLLCAEDKSQELLSIQKQMALVDKKLTKDDNVWLKKFENYKIYNQIYTEKESVR
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHCCHHHHH
QELRRLKFQKNKDLLKISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANP
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC
IAIIDGISFIKSMRLKHEDLKNNQIALEEVLKLLDEKHQLLSQWQALDKNAKLSDEIYQT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
QAKRLELQGAQNILKTTIGIFQKDSDEAVSIVKTQIKNQLLKLLYVFLTALLSVVFAWIL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVISSKYIENNERVYTVNKAINFVNVSVIVLIFLFSYLENVTYLVTVLGFASAGLAIAMK
HHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
DLFMSLLGWFIILIGGSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTLTTYSNNR
HHHHHHHHHHHHHHCCCEEECCEEEEECCCEEEEECHHHHHHHHEEEECCEEEEEECCCC
RAGRIVFVPNNYIFTTMFANYSHFGMKTVWDGVDFCVTFDSDFKKASKIALNIATELSKE
CCEEEEEECCCEEEEEEECCCCCCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
YTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSKITAEI
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCEEEEEHHHHHHHHH
IEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKR
HHHHHCCCCEEEEEEECEEEEEECCCCCCCCCC
>Mature Secondary Structure
MLFFCFLLLCAEDKSQELLSIQKQMALVDKKLTKDDNVWLKKFENYKIYNQIYTEKESVR
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHCCHHHHH
QELRRLKFQKNKDLLKISTLEHTLKALESQQKMFESYGVNPFKDLIERPNIPNIPNIANP
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC
IAIIDGISFIKSMRLKHEDLKNNQIALEEVLKLLDEKHQLLSQWQALDKNAKLSDEIYQT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
QAKRLELQGAQNILKTTIGIFQKDSDEAVSIVKTQIKNQLLKLLYVFLTALLSVVFAWIL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVISSKYIENNERVYTVNKAINFVNVSVIVLIFLFSYLENVTYLVTVLGFASAGLAIAMK
HHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
DLFMSLLGWFIILIGGSVHVGDRVRIAKGTDIFIGDVLDISMLHITILEDVTLTTYSNNR
HHHHHHHHHHHHHHCCCEEECCEEEEECCCEEEEECHHHHHHHHEEEECCEEEEEECCCC
RAGRIVFVPNNYIFTTMFANYSHFGMKTVWDGVDFCVTFDSDFKKASKIALNIATELSKE
CCEEEEEECCCEEEEEEECCCCCCCHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
YTDITYKQLNKMRDRYSLRSLSVKPRCFLMPENNGIKISVWYQTNSYATLSLRSKITAEI
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCEEEEEHHHHHHHHH
IEAFLKEENIHIAYTTSKLLKVDTEGDGFGNKR
HHHHHCCCCEEEEEEECEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]