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The map label for this gene is ccmB [H]

Identifier: 108812373

GI number: 108812373

Start: 2497808

End: 2498467

Strand: Reverse

Name: ccmB [H]

Synonym: YPN_2212

Alternate gene names: 108812373

Gene position: 2498467-2497808 (Counterclockwise)

Preceding gene: 108812374

Following gene: 108812372

Centisome position: 55.1

GC content: 52.12

Gene sequence:

>660_bases
ATGTTTATCAGCGTGTTGCGCCGTGAATTAAAAATAGCCTTTAGAAAAGGTGCGGAAATCGTTAACCCGCTGTGGTTCTT
TTTGATCGTTATTACGCTGTTCCCATTGGGGATAGGCCCAGAGCCACAATTGCTGGCTCGCATTGCACCGGGCATCGTGT
GGGTAGCGGCTTTGTTGGCCTCGTTACTCTCGTTGGAGCGCTTATTCCGTGATGATTTTTACGATGGCTCCCTTGAACAG
TTGCTGTTATTGCCTACACCACTCCCCCTCACCGTCTTAGGCAAAGTATGTGCTCACTGGGTCGTCACTGGGCTGCCTTT
ATTGGTGTTATCACCGCTGGTTGCTTTATTGCTTTCTCTGGACGTCAATACCGCTATCGCGATGGGGCTGACGCTCCTGC
TTGGGACACCAACACTGAGTTTTATCGGTGCTATCGGCGTGGCGTTGACGGTGGGGTTACGTAAAGGCGGGGTGCTGCTG
AGTCTATTGGTTTTGCCGCTGTATATCCCGGTTTTAATCTTTGCGACGGCGGCCATTGATGCCGCGTCAATGGCGATGCC
AATCGACGGTTATCTGGCTATTTTAGGTGCGATGCTGGCAGGGAGTGTGACACTTGCGCCTTTTGCGACGGCAGCAGCGT
TACGGGTGAGCATACAGTAA

Upstream 100 bases:

>100_bases
CGGCTAAGGGCGGAATGGTGCTGTTGACCACGCATCAGGATTTGGGCGCGGTTAGCCACAATGTCCGTAAAATTTGTTTA
GCCAACACGCAGGAGAAGTC

Downstream 100 bases:

>100_bases
TCACCCAATGGGCTGATGTTAAGTCTGCCTAATGTCCAATTTTTTACAGTGAGCAATGAAAAATGTGGAAATGGTTTCAT
CAATTTGCCAAACCTGAACG

Product: heme exporter protein B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPGIVWVAALLASLLSLERLFRDDFYDGSLEQ
LLLLPTPLPLTVLGKVCAHWVVTGLPLLVLSPLVALLLSLDVNTAIAMGLTLLLGTPTLSFIGAIGVALTVGLRKGGVLL
SLLVLPLYIPVLIFATAAIDAASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ

Sequences:

>Translated_219_residues
MFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPGIVWVAALLASLLSLERLFRDDFYDGSLEQ
LLLLPTPLPLTVLGKVCAHWVVTGLPLLVLSPLVALLLSLDVNTAIAMGLTLLLGTPTLSFIGAIGVALTVGLRKGGVLL
SLLVLPLYIPVLIFATAAIDAASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ
>Mature_219_residues
MFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPGIVWVAALLASLLSLERLFRDDFYDGSLEQ
LLLLPTPLPLTVLGKVCAHWVVTGLPLLVLSPLVALLLSLDVNTAIAMGLTLLLGTPTLSFIGAIGVALTVGLRKGGVLL
SLLVLPLYIPVLIFATAAIDAASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=219, Percent_Identity=77.1689497716895, Blast_Score=272, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23128; Mature: 23128

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPGIVWVAALLA
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SLLSLERLFRDDFYDGSLEQLLLLPTPLPLTVLGKVCAHWVVTGLPLLVLSPLVALLLSL
HHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVNTAIAMGLTLLLGTPTLSFIGAIGVALTVGLRKGGVLLSLLVLPLYIPVLIFATAAID
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ
HHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHEECC
>Mature Secondary Structure
MFISVLRRELKIAFRKGAEIVNPLWFFLIVITLFPLGIGPEPQLLARIAPGIVWVAALLA
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SLLSLERLFRDDFYDGSLEQLLLLPTPLPLTVLGKVCAHWVVTGLPLLVLSPLVALLLSL
HHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVNTAIAMGLTLLLGTPTLSFIGAIGVALTVGLRKGGVLLSLLVLPLYIPVLIFATAAID
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AASMAMPIDGYLAILGAMLAGSVTLAPFATAAALRVSIQ
HHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]