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The map label for this gene is ccmC [H]

Identifier: 108812372

GI number: 108812372

Start: 2497008

End: 2497745

Strand: Reverse

Name: ccmC [H]

Synonym: YPN_2211

Alternate gene names: 108812372

Gene position: 2497745-2497008 (Counterclockwise)

Preceding gene: 108812373

Following gene: 108812371

Centisome position: 55.08

GC content: 50.14

Gene sequence:

>738_bases
ATGTGGAAATGGTTTCATCAATTTGCCAAACCTGAACGGCTCTATCCGTTGTGTGGCCGCCTTATTCCGTGGTTCGGAGG
CGGGGCCATTATTTGTCTGGCTGTGGGCTGGGTATGGGGATTGGGTTTCGCACCATCGGATTATCAGCAAGGTGACAGTT
TCCGCATCATGTATTTACATGTTCCGGCGGCAATTTGGTCGATGGGTATCTATATGTCGATGGCTATTGCTGCGTTTGTG
GGATTGGTCTGGCAGATAAAAATGGCCGATAACCTGGTCGCGGCTATGGCTCCGGTGGGCGCAGTATTGACGTTTATTGC
TTTGGTCACCGGCTCTGCGTGGGGTAAACCGATGTGGGGGACTTGGTGGATCTGGGATGCACGGCTGACATCGGAATTAG
TCCTGTTATTCCTGTATCTCGGCGTGATCGCGCTATATAACGCGTTTGATGATCGTAAATTGGCTGGGCGAGCTGCCGGT
ATTCTGGTGTTGGTTGGCGTGGTTAATCTCCCTATTATTCATTTCTCCGTTGTTTGGTGGAATACCTTGCATCAAGGCTC
GACCAATATGCAGCAAAGTATTGATCCGAGTATGCGCTCACCTCTGCGCTGGGCGATTTTGGGTTTTCTTTTATGCTTTA
TCACACTGACATTAATGCGCTTGCGTAATTTGATTTTGCAGCAAGAGCGCCACCGTCCTTGGGTTACTGCCTTATTACGC
AAGGAGCCGCGCGTATGA

Upstream 100 bases:

>100_bases
TTGCGACGGCAGCAGCGTTACGGGTGAGCATACAGTAATCACCCAATGGGCTGATGTTAAGTCTGCCTAATGTCCAATTT
TTTACAGTGAGCAATGAAAA

Downstream 100 bases:

>100_bases
CCCCCGCTTTTCACTCATGGGCAGAATTTTTTGCCATGGGCAACTATGCCTTTTATGTCTGGCTCGCTGTGGCAGCCACC
TTGTTATCATTGCTGGGCTT

Product: heme exporter protein C

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MWKWFHQFAKPERLYPLCGRLIPWFGGGAIICLAVGWVWGLGFAPSDYQQGDSFRIMYLHVPAAIWSMGIYMSMAIAAFV
GLVWQIKMADNLVAAMAPVGAVLTFIALVTGSAWGKPMWGTWWIWDARLTSELVLLFLYLGVIALYNAFDDRKLAGRAAG
ILVLVGVVNLPIIHFSVVWWNTLHQGSTNMQQSIDPSMRSPLRWAILGFLLCFITLTLMRLRNLILQQERHRPWVTALLR
KEPRV

Sequences:

>Translated_245_residues
MWKWFHQFAKPERLYPLCGRLIPWFGGGAIICLAVGWVWGLGFAPSDYQQGDSFRIMYLHVPAAIWSMGIYMSMAIAAFV
GLVWQIKMADNLVAAMAPVGAVLTFIALVTGSAWGKPMWGTWWIWDARLTSELVLLFLYLGVIALYNAFDDRKLAGRAAG
ILVLVGVVNLPIIHFSVVWWNTLHQGSTNMQQSIDPSMRSPLRWAILGFLLCFITLTLMRLRNLILQQERHRPWVTALLR
KEPRV
>Mature_245_residues
MWKWFHQFAKPERLYPLCGRLIPWFGGGAIICLAVGWVWGLGFAPSDYQQGDSFRIMYLHVPAAIWSMGIYMSMAIAAFV
GLVWQIKMADNLVAAMAPVGAVLTFIALVTGSAWGKPMWGTWWIWDARLTSELVLLFLYLGVIALYNAFDDRKLAGRAAG
ILVLVGVVNLPIIHFSVVWWNTLHQGSTNMQQSIDPSMRSPLRWAILGFLLCFITLTLMRLRNLILQQERHRPWVTALLR
KEPRV

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=244, Percent_Identity=75.8196721311475, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 27832; Mature: 27832

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCC
>Mature Secondary Structure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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]