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The map label for this gene is gpsA2 [H]

Identifier: 108797753

GI number: 108797753

Start: 828415

End: 829440

Strand: Reverse

Name: gpsA2 [H]

Synonym: Mmcs_0774

Alternate gene names: 108797753

Gene position: 829440-828415 (Counterclockwise)

Preceding gene: 108797756

Following gene: 108797749

Centisome position: 14.54

GC content: 67.74

Gene sequence:

>1026_bases
ATGGCACACGCGCAACGACAACCCAAGGTCGTCGTCCTCGGAGGTGGGTCCTGGGGCACCACCGTCGCATCGATCTGTTC
CCGGCGCGCGCCCACGATCCAGTGGGTGCGCTCGGAGGACACCGCCAAGGACATCAACGCCAACCACCGCAACTCGCGCT
ACCTCGGCGAGGATGTGGTGTTGAGCGAGTCGCTGCGCGCGACCACCGACTTCGCCGAGGCCGCCAGCAGCGCCGACGTC
GTCGTCATGGGGGTGCCGTCACACGGATTCCGTGGGGTGCTCGAGAAACTCGCCGCCGAGCTGCGGCCGTGGGTGCCGGT
GGTGTCGCTGGTCAAGGGGCTCGAACAGGGCACCAACATGCGGATGAGCGAGATCGTCGACGAGGTGCTGCCCGGACACC
CGGCGGGCATCCTGGCCGGGCCGAACATCGCCCGTGAGGTCGCCGACGGGTACGCCGCCGCGGCGGTGCTGGCGATGCCC
GACCAGCACCTCGCCGCGCAGTTGGCAGAGTTGTTCCGCACCAAGCGTTTTCGCACCTACACCACCGACGACGTGGTCGG
CGTGGAGATGGCCGGCGCCCTGAAGAACGTCTACGCGATCGCCGTCGGCATGGGGTATTCACTCGGCATCGGCGAGAACA
CCCGCGCGATGGTGATCGCGCGCGCGGTGCGGGAGATGTCGAAACTCGGCGAGGCCATGGGCGGGCACCGCGATACCTTC
GCGGGCCTGGCCGGGATGGGTGACCTCATCGTCACCTGCACCAGCCAGCGCAGCCGCAACCGGCACGTGGGTGAACAGCT
GGGCTCGGGCAAGCCGATCGACGAGATCATCGCGTCGATGAACCAGGTCGCCGAGGGTGTGAAGGCCTCCAAGGTCATCA
TGGAGTTCGCCGACGAGTACGGGCTGAACATGCCGATCGCCCGTGAGGTCGACAGCGTGATCAACCACGGGTCGACGGTG
GAGCAGGCCTACCGCGGTCTGGTTGCAGAGAAGCCCGGCCACGAGGTGTACGGGTCGGGCTTCTAG

Upstream 100 bases:

>100_bases
CCCGAGCCGACTGGTTCTCAGTATCGCCCGTCGCGCGACGCGGTTGCTGCACCAATCGAATCGCCCTCCCGGCGACGGCG
CCCGTCCTACGCTGATCGCC

Downstream 100 bases:

>100_bases
GCCTCAGTTGAAGTAGGGGTTGCGGCCTTCGCGGGGCATCAGCAGCGGGTTGCTGGGCTGCAGGACGAAGCTCGCCGTGG
GGCTGATGACGAAGCCCGCG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2 [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAHAQRQPKVVVLGGGSWGTTVASICSRRAPTIQWVRSEDTAKDINANHRNSRYLGEDVVLSESLRATTDFAEAASSADV
VVMGVPSHGFRGVLEKLAAELRPWVPVVSLVKGLEQGTNMRMSEIVDEVLPGHPAGILAGPNIAREVADGYAAAAVLAMP
DQHLAAQLAELFRTKRFRTYTTDDVVGVEMAGALKNVYAIAVGMGYSLGIGENTRAMVIARAVREMSKLGEAMGGHRDTF
AGLAGMGDLIVTCTSQRSRNRHVGEQLGSGKPIDEIIASMNQVAEGVKASKVIMEFADEYGLNMPIAREVDSVINHGSTV
EQAYRGLVAEKPGHEVYGSGF

Sequences:

>Translated_341_residues
MAHAQRQPKVVVLGGGSWGTTVASICSRRAPTIQWVRSEDTAKDINANHRNSRYLGEDVVLSESLRATTDFAEAASSADV
VVMGVPSHGFRGVLEKLAAELRPWVPVVSLVKGLEQGTNMRMSEIVDEVLPGHPAGILAGPNIAREVADGYAAAAVLAMP
DQHLAAQLAELFRTKRFRTYTTDDVVGVEMAGALKNVYAIAVGMGYSLGIGENTRAMVIARAVREMSKLGEAMGGHRDTF
AGLAGMGDLIVTCTSQRSRNRHVGEQLGSGKPIDEIIASMNQVAEGVKASKVIMEFADEYGLNMPIAREVDSVINHGSTV
EQAYRGLVAEKPGHEVYGSGF
>Mature_340_residues
AHAQRQPKVVVLGGGSWGTTVASICSRRAPTIQWVRSEDTAKDINANHRNSRYLGEDVVLSESLRATTDFAEAASSADVV
VMGVPSHGFRGVLEKLAAELRPWVPVVSLVKGLEQGTNMRMSEIVDEVLPGHPAGILAGPNIAREVADGYAAAAVLAMPD
QHLAAQLAELFRTKRFRTYTTDDVVGVEMAGALKNVYAIAVGMGYSLGIGENTRAMVIARAVREMSKLGEAMGGHRDTFA
GLAGMGDLIVTCTSQRSRNRHVGEQLGSGKPIDEIIASMNQVAEGVKASKVIMEFADEYGLNMPIAREVDSVINHGSTVE
QAYRGLVAEKPGHEVYGSGF

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=336, Percent_Identity=31.8452380952381, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI24307999, Length=354, Percent_Identity=29.3785310734463, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1790037, Length=322, Percent_Identity=35.4037267080745, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI32564399, Length=289, Percent_Identity=33.5640138408304, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193210136, Length=298, Percent_Identity=32.8859060402685, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32564403, Length=298, Percent_Identity=32.8859060402685, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17507425, Length=352, Percent_Identity=28.6931818181818, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI193210134, Length=286, Percent_Identity=28.3216783216783, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324513, Length=288, Percent_Identity=29.8611111111111, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320181, Length=330, Percent_Identity=28.4848484848485, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI22026922, Length=286, Percent_Identity=27.6223776223776, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17136204, Length=290, Percent_Identity=29.6551724137931, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136202, Length=290, Percent_Identity=29.6551724137931, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136200, Length=290, Percent_Identity=29.6551724137931, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45551945, Length=291, Percent_Identity=25.7731958762887, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281362270, Length=291, Percent_Identity=25.7731958762887, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648969, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36373; Mature: 36242

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHAQRQPKVVVLGGGSWGTTVASICSRRAPTIQWVRSEDTAKDINANHRNSRYLGEDVV
CCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCCCCCCCCHHH
LSESLRATTDFAEAASSADVVVMGVPSHGFRGVLEKLAAELRPWVPVVSLVKGLEQGTNM
HHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
RMSEIVDEVLPGHPAGILAGPNIAREVADGYAAAAVLAMPDQHLAAQLAELFRTKRFRTY
HHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
TTDDVVGVEMAGALKNVYAIAVGMGYSLGIGENTRAMVIARAVREMSKLGEAMGGHRDTF
CCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
AGLAGMGDLIVTCTSQRSRNRHVGEQLGSGKPIDEIIASMNQVAEGVKASKVIMEFADEY
HHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLNMPIAREVDSVINHGSTVEQAYRGLVAEKPGHEVYGSGF
CCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AHAQRQPKVVVLGGGSWGTTVASICSRRAPTIQWVRSEDTAKDINANHRNSRYLGEDVV
CCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCCCCCCCCHHH
LSESLRATTDFAEAASSADVVVMGVPSHGFRGVLEKLAAELRPWVPVVSLVKGLEQGTNM
HHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
RMSEIVDEVLPGHPAGILAGPNIAREVADGYAAAAVLAMPDQHLAAQLAELFRTKRFRTY
HHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
TTDDVVGVEMAGALKNVYAIAVGMGYSLGIGENTRAMVIARAVREMSKLGEAMGGHRDTF
CCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
AGLAGMGDLIVTCTSQRSRNRHVGEQLGSGKPIDEIIASMNQVAEGVKASKVIMEFADEY
HHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLNMPIAREVDSVINHGSTVEQAYRGLVAEKPGHEVYGSGF
CCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]