Click here to switch to the map view.

The map label for this gene is 108797749

Identifier: 108797749

GI number: 108797749

Start: 824513

End: 825715

Strand: Reverse

Name: 108797749

Synonym: Mmcs_0770

Alternate gene names: NA

Gene position: 825715-824513 (Counterclockwise)

Preceding gene: 108797753

Following gene: 108797748

Centisome position: 14.47

GC content: 71.99

Gene sequence:

>1203_bases
GTGGTCGTTGTCGGCGCCGGACCTGCGGGTTCGGCTGCCGCGGCCTGGGCGGCCCGCGCCGGTCGCGACGTGTTGGTGAT
CGACTCCGCCCGCTTCCCGCGCGACAAGGCGTGCGGTGACGGGCTGACCCCGCGGGCGGTCGCCGAACTCGAACGCCTCG
GCCTCGGGCCGTGGCTGGACACCCGCATCCGCCACCGCGGTCTGCGGATGTCGGGATTCGGCGCGGCCGTGGAGGTCGCC
TGGCCCGGCCCGTCGTTCCCGTCCACCGGCAGCGCGGTGCCGCGCACCGAACTCGACGACCGGATCCGCTCCGTCGCCGC
CGACGACGGCGCCAAGATGCTCCTCGGCACCAAAGCCGTTGGTGTCGAACATGATTCGTCGGGACGCGTGGAGACGTTGA
CGCTGGACTCGGGTGAGGAGGTCGGTGTCGGGACCTTGATCGTCGCCGACGGGGCGCGGTCGACACTGGGCCGTGCGCTC
GGCCGGCAGTGGCATCAGCAGACCGTCTACGGCGTCGCGGTGCGCGGTTACCTCGCCAGCCCGCGCAGCGACGAACCGTG
GATCACGTCGCACCTGGAACTGCGGTCACCGGAGGGCAAGGTGCTGCCCGGCTACGGCTGGATCTTCCCGCTGGGCAACG
GTGAGGTGAACATCGGCGTCGGCGCCCTGGCGACCGAAAAACGGCCCGCCGACGCCGCTTTGCGGCCGCTGATGTCGCAT
TACACGGCGTTGCGGCGCGAGGAATGGGGCTTCGACGGTGAGCCGCGCGCACCGCTGTCCGCGCTGCTGCCGATGGGCGG
CGCGGTGTCGGGAGTCGCCGGCCCCAACTGGATGCTGATCGGGGACGCCGCGGCGTGTGTGAACCCGCTCAACGGCGAAG
GCATCGACTACGGGTTGGAGACCGGCCGGCTGGCCGCCGACCTGCTCGGCTCCAGTGACCTCTCACAGGCGTGGCCCGCC
GTGCTGAGCGACCACTACGCCCGCGGATTCTCCGTCGCGCGCCGGCTGGCGTTGCTGCTCACGCTGCCGAGATTCCTCCC
GCTGACCGGTCCGGTGGCGATGCGGTCGACGGCGCTGATGCGCATTGCGGTCCGGGTGATGGGCAACCTGGTCACCGACG
AGGACGCCGACTGGATCGCCCGGGTGTGGCGCGCGGGTGGTCTGGCCTCGCGCGGCCTGGACGCGCGCAAACCGTTCAGC
TGA

Upstream 100 bases:

>100_bases
TCGGCCGCGAAGGCCGCGTCGCCGAAGTCCACGCCCGCCACCACAGTCGCCGGTGTCCTCACCCTGCCAACATACTGTGA
CAATGAAGACCCGGGCGGAT

Downstream 100 bases:

>100_bases
TCAGCCGGCGACGCGGCCGGTCGTCGTCCGTGCGACTCGCATCGGTCAGCGCGAGCGCGATGAGGATGTCCGCGAAGGTG
ATGAACAGCCCCATCCAGTA

Product: geranylgeranyl reductase

Products: NA

Alternate protein names: DGGGPL reductase 1; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 1; Geranylgeranyl reductase 1; GGR 1 [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLGLGPWLDTRIRHRGLRMSGFGAAVEVA
WPGPSFPSTGSAVPRTELDDRIRSVAADDGAKMLLGTKAVGVEHDSSGRVETLTLDSGEEVGVGTLIVADGARSTLGRAL
GRQWHQQTVYGVAVRGYLASPRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAALRPLMSH
YTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAADLLGSSDLSQAWPA
VLSDHYARGFSVARRLALLLTLPRFLPLTGPVAMRSTALMRIAVRVMGNLVTDEDADWIARVWRAGGLASRGLDARKPFS

Sequences:

>Translated_400_residues
MVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLGLGPWLDTRIRHRGLRMSGFGAAVEVA
WPGPSFPSTGSAVPRTELDDRIRSVAADDGAKMLLGTKAVGVEHDSSGRVETLTLDSGEEVGVGTLIVADGARSTLGRAL
GRQWHQQTVYGVAVRGYLASPRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAALRPLMSH
YTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAADLLGSSDLSQAWPA
VLSDHYARGFSVARRLALLLTLPRFLPLTGPVAMRSTALMRIAVRVMGNLVTDEDADWIARVWRAGGLASRGLDARKPFS
>Mature_400_residues
MVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLGLGPWLDTRIRHRGLRMSGFGAAVEVA
WPGPSFPSTGSAVPRTELDDRIRSVAADDGAKMLLGTKAVGVEHDSSGRVETLTLDSGEEVGVGTLIVADGARSTLGRAL
GRQWHQQTVYGVAVRGYLASPRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAALRPLMSH
YTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAADLLGSSDLSQAWPA
VLSDHYARGFSVARRLALLLTLPRFLPLTGPVAMRSTALMRIAVRVMGNLVTDEDADWIARVWRAGGLASRGLDARKPFS

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR011777
- InterPro:   IPR003042 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 42219; Mature: 42219

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLGLGPWLD
CEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHH
TRIRHRGLRMSGFGAAVEVAWPGPSFPSTGSAVPRTELDDRIRSVAADDGAKMLLGTKAV
HHHHHCCCEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEE
GVEHDSSGRVETLTLDSGEEVGVGTLIVADGARSTLGRALGRQWHQQTVYGVAVRGYLAS
CCEECCCCCEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEEECC
PRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAALRPLMSH
CCCCCCCEEEEEEEECCCCCEECCCEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHH
YTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLE
HHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECHHHHCCCCCCCCCCCCCC
TGRLAADLLGSSDLSQAWPAVLSDHYARGFSVARRLALLLTLPRFLPLTGPVAMRSTALM
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RIAVRVMGNLVTDEDADWIARVWRAGGLASRGLDARKPFS
HHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCCCCCCCCC
>Mature Secondary Structure
MVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLGLGPWLD
CEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHH
TRIRHRGLRMSGFGAAVEVAWPGPSFPSTGSAVPRTELDDRIRSVAADDGAKMLLGTKAV
HHHHHCCCEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEE
GVEHDSSGRVETLTLDSGEEVGVGTLIVADGARSTLGRALGRQWHQQTVYGVAVRGYLAS
CCEECCCCCEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEEECC
PRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAALRPLMSH
CCCCCCCEEEEEEEECCCCCEECCCEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHH
YTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLE
HHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECHHHHCCCCCCCCCCCCCC
TGRLAADLLGSSDLSQAWPAVLSDHYARGFSVARRLALLLTLPRFLPLTGPVAMRSTALM
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RIAVRVMGNLVTDEDADWIARVWRAGGLASRGLDARKPFS
HHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA