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The map label for this gene is dnaK [H]

Identifier: 108797381

GI number: 108797381

Start: 446915

End: 448699

Strand: Direct

Name: dnaK [H]

Synonym: Mmcs_0401

Alternate gene names: 108797381

Gene position: 446915-448699 (Clockwise)

Preceding gene: 108797379

Following gene: 108797382

Centisome position: 7.83

GC content: 72.66

Gene sequence:

>1785_bases
ATGAGCGACCCGTTGGGCTTGTCGATCGGGACCACCAACCTGGTTGCGGCACGAGTCGGCAATCCACCTGTCATACGGCG
TTCGACGCTGAGCCTGTTCAGCGATCGCACGCCGCAGGTCGGGCTGCCCGCCGAACAGTCCGGGGGCGTGGTGCTCGACG
GTTTCGTCGAGCGGGTCGGCGACCCCGTCCCACTCGTCGCCGCCGACGGCACCTCCTACCGCGCCGACGCCCTGCTGGTC
GAGGCGCTCGACGCGATGACCGAGGCCGTCGACGCGGCACCCAGCGGTGACATCGCCATCGCCGTGCCCGCGCACTGGGG
TACCGCCACGGTCTACGCGTTGCGCAACGCGCTGCGCACCAACCCCGTCTTCACATCCAACGGCGCCCCCGCGCGCCTGG
TGTCCGATGCGGTCGCCTCGCTGACCGCGCTGCGCGCCAACCCCGGACTGCCCACCGACGGAGTGGTGGCGCTGCTCGAC
TTCGGTGGCAGCGGCACCAGCATCACCCTCGCGGACGCCGCCGCGGGTTTCGCGCCGGTCGACGAGACCACCCGGTTCAC
CGAGTTCTCCGGTGACCTGATCGATCAGGCGTTGCTCACCCACGTACTGACCGGGATCACCGACGCCGGTGGCGTCGACC
CCGCGGGTACCGCGGCGGTCGGATCACTGACCCGGCTGCGGGAACGGTGCCGCGACGCCAAGGAGCGGCTGTCGGCGGTG
ACGGCCGCCGACGTGGCCGCCGAACTGCCCGGCTACCACTCGACGATCCGGATCACCCGCGCCGAACTCGAGGAGATGCT
GCAACGCCCGCTGGCCGGGGTGCTGGCCGCGCTCGACGCCGCGTTGGAACGGACCCGCATCGGATGGGCGGGTGTCTCGG
CAGTCGTCACCATCGGCGGCGGAGCGAGCATCCCGCTGATCACCCAACAACTCTCGGCGCACACCCGTGTCCCCGTGATC
ACCACGCGGCAACCGGCGCTCGACGCCGCGGTCGGTGCCGCCCTGTTCGCCGCCTACAGCGCGGCCGCGGAGGCGCCGAC
GGGGATGGCCGCCGCCGCACCCGTCACCGCGATGATCGACGACGCCCCGGGGTCGGCGACCTTCCGCGCACTGGCCTGGT
CGCAGGACGACACGACGTCGGACGAACCCGTGCCCTACACCGGTGACGACGCCTACGAGCCGTACAACCCGTTCGGACCC
GCGCCCACCGGTGCCCGGCCGGAGGTGCAGTACCTGCCCGCCGACGAACCGGAGGACGGGCGGCGCGGCTGGCACGTGCC
GCAGTTGGCGTTCGGCGCCGCGGCGGTGGTCGCGGCGATCGCCGTCGGCGGCGTCGCCTATGCGTTGACCTCGACGTCGG
CCGACAGCACACCGGTCACCGAGTTCGAGACCACCCGGCTGCCCGCCGGCGCGCCCCTGCCCGAGCCGTCGAGTGCGCCG
CCGCCCCCGGTCGTCACCGTCACCACGGCGCCGCCCGCGCCCGCTCCGCCACCCGAGCCCGGCACGCCCCTGCCCCCGCC
ACCACCCGTGACGCCGGTGACCACGACGCCGACCACCACCACCACGACGACGACCACCACGACGACGACCACGACAACCA
CAACCACCACGACGACGCAGCCGACCACGACGACGACGCAGCCGACGACCACACAGCCGACCACGACCCAGCCGACGACC
ACACAGCCGCCGGTGACCACGACGACGCAGCCGCCGGTGACCACGACGTACGTGACAGTGCCGTTCGTGCCGATCCCCAT
CCCGATCCAGGTGCCCAACAACTGA

Upstream 100 bases:

>100_bases
CAGCCACAGTGACGTCATGCGGGGGTGTTACCCCCCGTGAACCCGCCGAAACGAGGGGTTGACGGCAGGCGGACAACGAT
GCCACTAGGGTGATTACCCG

Downstream 100 bases:

>100_bases
CGTAACACCTTGAGCGGCAGGCGAATCCGATCCCGCTTGCGCCGGCGGGTTTCCGCGCACGCGTTCGGGGTAACACTATG
CAAAGCCCTCCGCGTGGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MSDPLGLSIGTTNLVAARVGNPPVIRRSTLSLFSDRTPQVGLPAEQSGGVVLDGFVERVGDPVPLVAADGTSYRADALLV
EALDAMTEAVDAAPSGDIAIAVPAHWGTATVYALRNALRTNPVFTSNGAPARLVSDAVASLTALRANPGLPTDGVVALLD
FGGSGTSITLADAAAGFAPVDETTRFTEFSGDLIDQALLTHVLTGITDAGGVDPAGTAAVGSLTRLRERCRDAKERLSAV
TAADVAAELPGYHSTIRITRAELEEMLQRPLAGVLAALDAALERTRIGWAGVSAVVTIGGGASIPLITQQLSAHTRVPVI
TTRQPALDAAVGAALFAAYSAAAEAPTGMAAAAPVTAMIDDAPGSATFRALAWSQDDTTSDEPVPYTGDDAYEPYNPFGP
APTGARPEVQYLPADEPEDGRRGWHVPQLAFGAAAVVAAIAVGGVAYALTSTSADSTPVTEFETTRLPAGAPLPEPSSAP
PPPVVTVTTAPPAPAPPPEPGTPLPPPPPVTPVTTTPTTTTTTTTTTTTTTTTTTTTTTQPTTTTTQPTTTQPTTTQPTT
TQPPVTTTTQPPVTTTYVTVPFVPIPIPIQVPNN

Sequences:

>Translated_594_residues
MSDPLGLSIGTTNLVAARVGNPPVIRRSTLSLFSDRTPQVGLPAEQSGGVVLDGFVERVGDPVPLVAADGTSYRADALLV
EALDAMTEAVDAAPSGDIAIAVPAHWGTATVYALRNALRTNPVFTSNGAPARLVSDAVASLTALRANPGLPTDGVVALLD
FGGSGTSITLADAAAGFAPVDETTRFTEFSGDLIDQALLTHVLTGITDAGGVDPAGTAAVGSLTRLRERCRDAKERLSAV
TAADVAAELPGYHSTIRITRAELEEMLQRPLAGVLAALDAALERTRIGWAGVSAVVTIGGGASIPLITQQLSAHTRVPVI
TTRQPALDAAVGAALFAAYSAAAEAPTGMAAAAPVTAMIDDAPGSATFRALAWSQDDTTSDEPVPYTGDDAYEPYNPFGP
APTGARPEVQYLPADEPEDGRRGWHVPQLAFGAAAVVAAIAVGGVAYALTSTSADSTPVTEFETTRLPAGAPLPEPSSAP
PPPVVTVTTAPPAPAPPPEPGTPLPPPPPVTPVTTTPTTTTTTTTTTTTTTTTTTTTTTQPTTTTTQPTTTQPTTTQPTT
TQPPVTTTTQPPVTTTYVTVPFVPIPIPIQVPNN
>Mature_593_residues
SDPLGLSIGTTNLVAARVGNPPVIRRSTLSLFSDRTPQVGLPAEQSGGVVLDGFVERVGDPVPLVAADGTSYRADALLVE
ALDAMTEAVDAAPSGDIAIAVPAHWGTATVYALRNALRTNPVFTSNGAPARLVSDAVASLTALRANPGLPTDGVVALLDF
GGSGTSITLADAAAGFAPVDETTRFTEFSGDLIDQALLTHVLTGITDAGGVDPAGTAAVGSLTRLRERCRDAKERLSAVT
AADVAAELPGYHSTIRITRAELEEMLQRPLAGVLAALDAALERTRIGWAGVSAVVTIGGGASIPLITQQLSAHTRVPVIT
TRQPALDAAVGAALFAAYSAAAEAPTGMAAAAPVTAMIDDAPGSATFRALAWSQDDTTSDEPVPYTGDDAYEPYNPFGPA
PTGARPEVQYLPADEPEDGRRGWHVPQLAFGAAAVVAAIAVGGVAYALTSTSADSTPVTEFETTRLPAGAPLPEPSSAPP
PPVVTVTTAPPAPAPPPEPGTPLPPPPPVTPVTTTPTTTTTTTTTTTTTTTTTTTTTTQPTTTTTQPTTTQPTTTQPTTT
QPPVTTTTQPPVTTTYVTVPFVPIPIPIQVPNN

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17534015, Length=264, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17534013, Length=264, Percent_Identity=24.2424242424242, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507981, Length=264, Percent_Identity=25.7575757575758, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 320 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stati

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 60517; Mature: 60386

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPLGLSIGTTNLVAARVGNPPVIRRSTLSLFSDRTPQVGLPAEQSGGVVLDGFVERVG
CCCCCCEEECCCEEEEEECCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHCC
DPVPLVAADGTSYRADALLVEALDAMTEAVDAAPSGDIAIAVPAHWGTATVYALRNALRT
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHC
NPVFTSNGAPARLVSDAVASLTALRANPGLPTDGVVALLDFGGSGTSITLADAAAGFAPV
CCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCC
DETTRFTEFSGDLIDQALLTHVLTGITDAGGVDPAGTAAVGSLTRLRERCRDAKERLSAV
CCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAADVAAELPGYHSTIRITRAELEEMLQRPLAGVLAALDAALERTRIGWAGVSAVVTIGG
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
GASIPLITQQLSAHTRVPVITTRQPALDAAVGAALFAAYSAAAEAPTGMAAAAPVTAMID
CCCCHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEE
DAPGSATFRALAWSQDDTTSDEPVPYTGDDAYEPYNPFGPAPTGARPEVQYLPADEPEDG
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
RRGWHVPQLAFGAAAVVAAIAVGGVAYALTSTSADSTPVTEFETTRLPAGAPLPEPSSAP
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCC
PPPVVTVTTAPPAPAPPPEPGTPLPPPPPVTPVTTTPTTTTTTTTTTTTTTTTTTTTTTQ
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCC
PTTTTTQPTTTQPTTTQPTTTQPPVTTTTQPPVTTTYVTVPFVPIPIPIQVPNN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECEEECEEEEECCCC
>Mature Secondary Structure 
SDPLGLSIGTTNLVAARVGNPPVIRRSTLSLFSDRTPQVGLPAEQSGGVVLDGFVERVG
CCCCCEEECCCEEEEEECCCCCEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHCC
DPVPLVAADGTSYRADALLVEALDAMTEAVDAAPSGDIAIAVPAHWGTATVYALRNALRT
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHC
NPVFTSNGAPARLVSDAVASLTALRANPGLPTDGVVALLDFGGSGTSITLADAAAGFAPV
CCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCC
DETTRFTEFSGDLIDQALLTHVLTGITDAGGVDPAGTAAVGSLTRLRERCRDAKERLSAV
CCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TAADVAAELPGYHSTIRITRAELEEMLQRPLAGVLAALDAALERTRIGWAGVSAVVTIGG
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
GASIPLITQQLSAHTRVPVITTRQPALDAAVGAALFAAYSAAAEAPTGMAAAAPVTAMID
CCCCHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEE
DAPGSATFRALAWSQDDTTSDEPVPYTGDDAYEPYNPFGPAPTGARPEVQYLPADEPEDG
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
RRGWHVPQLAFGAAAVVAAIAVGGVAYALTSTSADSTPVTEFETTRLPAGAPLPEPSSAP
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCC
PPPVVTVTTAPPAPAPPPEPGTPLPPPPPVTPVTTTPTTTTTTTTTTTTTTTTTTTTTTQ
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCC
PTTTTTQPTTTQPTTTQPTTTQPPVTTTTQPPVTTTYVTVPFVPIPIPIQVPNN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECEEECEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA