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The map label for this gene is zraR [H]

Identifier: 108763029

GI number: 108763029

Start: 4579078

End: 4580511

Strand: Reverse

Name: zraR [H]

Synonym: MXAN_3811

Alternate gene names: 108763029

Gene position: 4580511-4579078 (Counterclockwise)

Preceding gene: 108759565

Following gene: 108757751

Centisome position: 50.12

GC content: 70.15

Gene sequence:

>1434_bases
ATGTGGGATGAGGCCAAGGAGGGTGGCACCACGCGCGTCCTGGTGGTGGATGACGACGCGGGCGTTCGCTTCACGCTGCG
GGAGATGCTCAAGAGCCTCTCCGGCGTCGAGGTGGATGAAGCCGTGGATGGCGAGGACGCGCTGGAGAAGCTGTCGGCCA
GGCCCTACGAGTTGGTCATCTCCGACCTGCGCATGCCTCGGATGGATGGCATGGAACTGGTGCGCCGGCTGAGTCTGTTC
TCCCGGTCACCTCGTGTCATCGTCATCACCGCGCATGGTTCCGAGCGCTTCGCGGTGGAGGCCATGAAGGCGGGGGCCTA
CGACTACTTCCGCAAGCCCTTCGATGTGGATGAGCTGCTGGCGGTCGTCTCCCGCGCGCTGGAGTCGGTACGGCTCCGCG
AGGAGAACGCACGGCTTTCAGGTGAGCTGAACCTGTCCCGCTCGTTGGTGTTCGTCTCGGAGCCCATGGCCCGGCTCGCG
CAGCTCGTGCAACGGGCGGGCTCACGGGATGTGACGGTGCTCATCACCGGCGAGAGCGGCACGGGCAAGGAGCGGGTGGC
GGATGCGCTCGTCCGCGCCTCGCCGCGCGCGAACCGGCCCTTCCTGCGCTTCAACTGCGCCGCACTCACCGAGGAACTGG
CGGAGGCCGAGCTGTTCGGCCACGCCCGGGGCGCCTTCACTGGAGCCCACCGCGCGCGGCCTGGGCTCTTCCGTGAGGCG
GATGGCGGCACGCTGCTGTTGGACGAGGTGGGCGAGCTGGCGCCCACGCTCCAGGCCCGGCTCCTTCGCGTGCTTCAGGA
GGGCGAGGTGCGCCCGGTGGGGGAGGACCGGCCGGTGACGGTGGACGTGCGCATCATCGCCGCCACCCACAGGGACTTGC
GCCGCCTGGCCCTGGAGGGGGCGTTCCGCGAGGACCTCTACTACCGGCTCAACGTCGTCCAGCTCCGGGTGCCGCCGCTG
CGCGAGCGCCCCGAGGACATCCCCGTGCTGGCGCGGGTGTTCCTGGACCGCTTCATCGACCGGTTCCACACCGGCCCGCT
GAAAATCCCCGACGGCTTCTTCGAGCAGCTCCGTGCCTTGCCGTGGCCGGGTAACGTGCGCGAACTGGAGAACACGCTGG
AGAGCCTGGTCGCGCTGTCCAGCGAGGGGCGGCTGGACCTGGGTCAGTTGCCTTCCGCCGAGCCGGCAGGAGCGGATAGT
GGTTTCCCGGGGGCGTCATCGGACCCGGTCCGTCCAGGGCCGCAGGACGGGGCTCCCGGCGCGGGGCTCAAGGAGCGCGT
GGAGGCGTACGAGCGCGGCCTGGTCCTGGACGCGCTGCGCATCGCGGGCGGAAACCGCAGTGAAGCGGCGCGGCGGCTGG
GCATTGGCCGGGCCACCCTGCATGACAAGCTGCGCAAGTACGGGCTGGACGACGGCGGGGAAGAGCGGAGCTGA

Upstream 100 bases:

>100_bases
GTCACGCTGGCGAATGCGGTAGGAGGCGGATGCGAGGCGGCGTTGACGCTTCCGCGAGAGCTGCCAGCGGAGATCCTGCG
GCCACTGCACGGAGTCGCGA

Downstream 100 bases:

>100_bases
TTCCGGGAACAAGCGGGCCGCTCGCGGTGTTGCGGGCCGGCCTTCCAGCGTCATCGTTCCAGGAGCGTGCATGCATCCCG
TGACCCGATGCCTCGCGGCT

Product: sigma-54 dependent DNA-binding reponse regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MWDEAKEGGTTRVLVVDDDAGVRFTLREMLKSLSGVEVDEAVDGEDALEKLSARPYELVISDLRMPRMDGMELVRRLSLF
SRSPRVIVITAHGSERFAVEAMKAGAYDYFRKPFDVDELLAVVSRALESVRLREENARLSGELNLSRSLVFVSEPMARLA
QLVQRAGSRDVTVLITGESGTGKERVADALVRASPRANRPFLRFNCAALTEELAEAELFGHARGAFTGAHRARPGLFREA
DGGTLLLDEVGELAPTLQARLLRVLQEGEVRPVGEDRPVTVDVRIIAATHRDLRRLALEGAFREDLYYRLNVVQLRVPPL
RERPEDIPVLARVFLDRFIDRFHTGPLKIPDGFFEQLRALPWPGNVRELENTLESLVALSSEGRLDLGQLPSAEPAGADS
GFPGASSDPVRPGPQDGAPGAGLKERVEAYERGLVLDALRIAGGNRSEAARRLGIGRATLHDKLRKYGLDDGGEERS

Sequences:

>Translated_477_residues
MWDEAKEGGTTRVLVVDDDAGVRFTLREMLKSLSGVEVDEAVDGEDALEKLSARPYELVISDLRMPRMDGMELVRRLSLF
SRSPRVIVITAHGSERFAVEAMKAGAYDYFRKPFDVDELLAVVSRALESVRLREENARLSGELNLSRSLVFVSEPMARLA
QLVQRAGSRDVTVLITGESGTGKERVADALVRASPRANRPFLRFNCAALTEELAEAELFGHARGAFTGAHRARPGLFREA
DGGTLLLDEVGELAPTLQARLLRVLQEGEVRPVGEDRPVTVDVRIIAATHRDLRRLALEGAFREDLYYRLNVVQLRVPPL
RERPEDIPVLARVFLDRFIDRFHTGPLKIPDGFFEQLRALPWPGNVRELENTLESLVALSSEGRLDLGQLPSAEPAGADS
GFPGASSDPVRPGPQDGAPGAGLKERVEAYERGLVLDALRIAGGNRSEAARRLGIGRATLHDKLRKYGLDDGGEERS
>Mature_477_residues
MWDEAKEGGTTRVLVVDDDAGVRFTLREMLKSLSGVEVDEAVDGEDALEKLSARPYELVISDLRMPRMDGMELVRRLSLF
SRSPRVIVITAHGSERFAVEAMKAGAYDYFRKPFDVDELLAVVSRALESVRLREENARLSGELNLSRSLVFVSEPMARLA
QLVQRAGSRDVTVLITGESGTGKERVADALVRASPRANRPFLRFNCAALTEELAEAELFGHARGAFTGAHRARPGLFREA
DGGTLLLDEVGELAPTLQARLLRVLQEGEVRPVGEDRPVTVDVRIIAATHRDLRRLALEGAFREDLYYRLNVVQLRVPPL
RERPEDIPVLARVFLDRFIDRFHTGPLKIPDGFFEQLRALPWPGNVRELENTLESLVALSSEGRLDLGQLPSAEPAGADS
GFPGASSDPVRPGPQDGAPGAGLKERVEAYERGLVLDALRIAGGNRSEAARRLGIGRATLHDKLRKYGLDDGGEERS

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=466, Percent_Identity=41.2017167381974, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI1790299, Length=475, Percent_Identity=40.6315789473684, Blast_Score=318, Evalue=6e-88,
Organism=Escherichia coli, GI1790437, Length=458, Percent_Identity=42.3580786026201, Blast_Score=315, Evalue=4e-87,
Organism=Escherichia coli, GI1788905, Length=463, Percent_Identity=41.4686825053996, Blast_Score=296, Evalue=3e-81,
Organism=Escherichia coli, GI87082117, Length=392, Percent_Identity=39.2857142857143, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789087, Length=350, Percent_Identity=41.1428571428571, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=41.875, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI87082152, Length=327, Percent_Identity=42.5076452599388, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1787583, Length=328, Percent_Identity=39.3292682926829, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1786524, Length=334, Percent_Identity=37.7245508982036, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081872, Length=249, Percent_Identity=43.3734939759036, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1789828, Length=224, Percent_Identity=39.2857142857143, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081858, Length=326, Percent_Identity=32.2085889570552, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788191, Length=122, Percent_Identity=39.344262295082, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787375, Length=110, Percent_Identity=38.1818181818182, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786911, Length=117, Percent_Identity=39.3162393162393, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=33.8983050847458, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52551; Mature: 52551

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDEAKEGGTTRVLVVDDDAGVRFTLREMLKSLSGVEVDEAVDGEDALEKLSARPYELVI
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHCCCCHHHHHHHCCCCHHHHH
SDLRMPRMDGMELVRRLSLFSRSPRVIVITAHGSERFAVEAMKAGAYDYFRKPFDVDELL
HHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCHHHHCCCCCHHHHH
AVVSRALESVRLREENARLSGELNLSRSLVFVSEPMARLAQLVQRAGSRDVTVLITGESG
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCC
TGKERVADALVRASPRANRPFLRFNCAALTEELAEAELFGHARGAFTGAHRARPGLFREA
CCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCEEC
DGGTLLLDEVGELAPTLQARLLRVLQEGEVRPVGEDRPVTVDVRIIAATHRDLRRLALEG
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHH
AFREDLYYRLNVVQLRVPPLRERPEDIPVLARVFLDRFIDRFHTGPLKIPDGFFEQLRAL
HHHHHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
PWPGNVRELENTLESLVALSSEGRLDLGQLPSAEPAGADSGFPGASSDPVRPGPQDGAPG
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGLKERVEAYERGLVLDALRIAGGNRSEAARRLGIGRATLHDKLRKYGLDDGGEERS
CCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MWDEAKEGGTTRVLVVDDDAGVRFTLREMLKSLSGVEVDEAVDGEDALEKLSARPYELVI
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHCCCCHHHHHHHCCCCHHHHH
SDLRMPRMDGMELVRRLSLFSRSPRVIVITAHGSERFAVEAMKAGAYDYFRKPFDVDELL
HHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCHHHHCCCCCHHHHH
AVVSRALESVRLREENARLSGELNLSRSLVFVSEPMARLAQLVQRAGSRDVTVLITGESG
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCC
TGKERVADALVRASPRANRPFLRFNCAALTEELAEAELFGHARGAFTGAHRARPGLFREA
CCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCEEC
DGGTLLLDEVGELAPTLQARLLRVLQEGEVRPVGEDRPVTVDVRIIAATHRDLRRLALEG
CCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEHHHHHHHHHHHHH
AFREDLYYRLNVVQLRVPPLRERPEDIPVLARVFLDRFIDRFHTGPLKIPDGFFEQLRAL
HHHHHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
PWPGNVRELENTLESLVALSSEGRLDLGQLPSAEPAGADSGFPGASSDPVRPGPQDGAPG
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGLKERVEAYERGLVLDALRIAGGNRSEAARRLGIGRATLHDKLRKYGLDDGGEERS
CCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]