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The map label for this gene is aroA [H]

Identifier: 108757763

GI number: 108757763

Start: 4100239

End: 4101531

Strand: Reverse

Name: aroA [H]

Synonym: MXAN_3520

Alternate gene names: 108757763

Gene position: 4101531-4100239 (Counterclockwise)

Preceding gene: 108764062

Following gene: 108762008

Centisome position: 44.88

GC content: 71.69

Gene sequence:

>1293_bases
ATGAGCACGGCGAAGGCTTCCCGTATCGTGGTGGACCCATCCGCGCTGCACGCCGCGCCCCTCACCCCGCCAGTGTCCAA
GTCGGACGCGCAGCGGGCGCTGGTGCTGGGGCACCTCACGGGCTCGTGGCCGCTGCCCTCGGTGCAGGCCGAGGCGGACG
AGGACCTCCCCGCCGACGTGCGCGTGCTGCGCCAGGGCGTCGAGGCCCTGCGTCTGCCTCCGGACGCCGTGCGCGACATC
GACTGCGCGGACGGTGGCGCGCCCTTCCGCATCCTGGCCACCCAGGCGGCGGTGACGCCCGGCGCTCAGGCGCGCTTCAC
CGGCACACCCCGCCTGGGCGAGCGGCCCCACGGCCCGCTCTTCACGTCCCTGCGCGAGGCCCTGGGTCCCATGGGCCTCA
CGCTCACCGAGGGCACGCCCTGGCCCGTGGAGCTGCGCGCGCCCCGTGATACGTCGAACGCCACTCCCGTGTTCCGCGTG
CCGGGCGCCCAGAGCAGCCAGTACGCCTCCAGCCTGCTGCTGGGCTGCGCGGCGCTGTACCTGCGCGAGCGCCGCCCCTG
GCGCGTGGAGATTGACGGGCCCCTCACCAGCGCGGGATACCTGGAGCTGACCCTCACGTGGCTGAGCCGCTTCGGCTTCG
ACATCCTGCGCTCCCCGTCGAGCTACACCGTGGCCGGGTACGCGGCGCCCCCGGCCGTCCCCACGCTTCCGGGGGATTGG
TCGTCCCTGGGCTACCTGCTGCTGGTGGCGTGGAAGACGGGCGGCACCGTGGTGCGCGCGGACACAGGCAGTGCCCACCC
GGACGACGCCATTGTCCGGTTGATTGAGCAGGTGGGCCTGCGCGCGGTGCCCGCGGGCCCTCCCTTCACGCTCAAGGTGG
AGGGCCAGCTTTCAGGGGGCCTTCGCGCCTCCGGCGAGGAATGCCCGGACCTGCTCCCCACGCTGGCCGCCCTCGCCTGC
GTGCTTCCCGCGCCCTCCACGCTCACGGAGGTGGGTATCCTCCGCGTCAAGGAGAGCGACCGTCTCGAGGGCATCCGGAC
GCTCGTGAAGGCGTTCGGCGGAACCACGGAGCTCCAAGGAGAACAGCTGCTGATCCAGCCACCCCGCACGCCACCTGCGG
GCTTCGAGATGAGCAGCGAGGGGGACCATCGTCTCGCGATGACCGCTGCGACACTGTGTGTCCTGTCCGGCACGCCGCTG
ACACTCACCGGTCCAGAGTGCGTGGAAAAGAGCTTTCCTGGGTTCTGGCGCCAGTTGTCCAGGGTGGGTGTTCGGATAAC
TGATGCAGGATGA

Upstream 100 bases:

>100_bases
GCATGGTGCTGCTGACGGCCATTGGCGCCACCGAGGTGCGTGACGTGGACGAATCAAGCTGGCGTGCCTTGTGGCCCGCG
TGGACGAAGGGGGAGCGACC

Downstream 100 bases:

>100_bases
GACCCCCAGTGTCCGTCCAGCAGACTTATCGTTCTTTTTTGTTGAAAGCACTCTCCCCCCTGTGAAATCTCCGCCCCATG
GCCAAGGACACGCTGACGAT

Product: putative 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSTAKASRIVVDPSALHAAPLTPPVSKSDAQRALVLGHLTGSWPLPSVQAEADEDLPADVRVLRQGVEALRLPPDAVRDI
DCADGGAPFRILATQAAVTPGAQARFTGTPRLGERPHGPLFTSLREALGPMGLTLTEGTPWPVELRAPRDTSNATPVFRV
PGAQSSQYASSLLLGCAALYLRERRPWRVEIDGPLTSAGYLELTLTWLSRFGFDILRSPSSYTVAGYAAPPAVPTLPGDW
SSLGYLLLVAWKTGGTVVRADTGSAHPDDAIVRLIEQVGLRAVPAGPPFTLKVEGQLSGGLRASGEECPDLLPTLAALAC
VLPAPSTLTEVGILRVKESDRLEGIRTLVKAFGGTTELQGEQLLIQPPRTPPAGFEMSSEGDHRLAMTAATLCVLSGTPL
TLTGPECVEKSFPGFWRQLSRVGVRITDAG

Sequences:

>Translated_430_residues
MSTAKASRIVVDPSALHAAPLTPPVSKSDAQRALVLGHLTGSWPLPSVQAEADEDLPADVRVLRQGVEALRLPPDAVRDI
DCADGGAPFRILATQAAVTPGAQARFTGTPRLGERPHGPLFTSLREALGPMGLTLTEGTPWPVELRAPRDTSNATPVFRV
PGAQSSQYASSLLLGCAALYLRERRPWRVEIDGPLTSAGYLELTLTWLSRFGFDILRSPSSYTVAGYAAPPAVPTLPGDW
SSLGYLLLVAWKTGGTVVRADTGSAHPDDAIVRLIEQVGLRAVPAGPPFTLKVEGQLSGGLRASGEECPDLLPTLAALAC
VLPAPSTLTEVGILRVKESDRLEGIRTLVKAFGGTTELQGEQLLIQPPRTPPAGFEMSSEGDHRLAMTAATLCVLSGTPL
TLTGPECVEKSFPGFWRQLSRVGVRITDAG
>Mature_429_residues
STAKASRIVVDPSALHAAPLTPPVSKSDAQRALVLGHLTGSWPLPSVQAEADEDLPADVRVLRQGVEALRLPPDAVRDID
CADGGAPFRILATQAAVTPGAQARFTGTPRLGERPHGPLFTSLREALGPMGLTLTEGTPWPVELRAPRDTSNATPVFRVP
GAQSSQYASSLLLGCAALYLRERRPWRVEIDGPLTSAGYLELTLTWLSRFGFDILRSPSSYTVAGYAAPPAVPTLPGDWS
SLGYLLLVAWKTGGTVVRADTGSAHPDDAIVRLIEQVGLRAVPAGPPFTLKVEGQLSGGLRASGEECPDLLPTLAALACV
LPAPSTLTEVGILRVKESDRLEGIRTLVKAFGGTTELQGEQLLIQPPRTPPAGFEMSSEGDHRLAMTAATLCVLSGTPLT
LTGPECVEKSFPGFWRQLSRVGVRITDAG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=323, Percent_Identity=30.6501547987616, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45444; Mature: 45313

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAKASRIVVDPSALHAAPLTPPVSKSDAQRALVLGHLTGSWPLPSVQAEADEDLPADV
CCCCCCCEEEECCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHH
RVLRQGVEALRLPPDAVRDIDCADGGAPFRILATQAAVTPGAQARFTGTPRLGERPHGPL
HHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEEHHHCCCCCCEEECCCCCCCCCCCCHH
FTSLREALGPMGLTLTEGTPWPVELRAPRDTSNATPVFRVPGAQSSQYASSLLLGCAALY
HHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
LRERRPWRVEIDGPLTSAGYLELTLTWLSRFGFDILRSPSSYTVAGYAAPPAVPTLPGDW
HHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCHHHHCCCCCEEEEEECCCCCCCCCCCCH
SSLGYLLLVAWKTGGTVVRADTGSAHPDDAIVRLIEQVGLRAVPAGPPFTLKVEGQLSGG
HCCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCC
LRASGEECPDLLPTLAALACVLPAPSTLTEVGILRVKESDRLEGIRTLVKAFGGTTELQG
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEEECCCHHHHHHHHHHHHHCCCCEECC
EQLLIQPPRTPPAGFEMSSEGDHRLAMTAATLCVLSGTPLTLTGPECVEKSFPGFWRQLS
CEEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHEECCCCEEECCHHHHHHCCCHHHHHHH
RVGVRITDAG
HCCEEEECCC
>Mature Secondary Structure 
STAKASRIVVDPSALHAAPLTPPVSKSDAQRALVLGHLTGSWPLPSVQAEADEDLPADV
CCCCCCEEEECCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHH
RVLRQGVEALRLPPDAVRDIDCADGGAPFRILATQAAVTPGAQARFTGTPRLGERPHGPL
HHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEEEHHHCCCCCCEEECCCCCCCCCCCCHH
FTSLREALGPMGLTLTEGTPWPVELRAPRDTSNATPVFRVPGAQSSQYASSLLLGCAALY
HHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
LRERRPWRVEIDGPLTSAGYLELTLTWLSRFGFDILRSPSSYTVAGYAAPPAVPTLPGDW
HHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCHHHHCCCCCEEEEEECCCCCCCCCCCCH
SSLGYLLLVAWKTGGTVVRADTGSAHPDDAIVRLIEQVGLRAVPAGPPFTLKVEGQLSGG
HCCCEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCC
LRASGEECPDLLPTLAALACVLPAPSTLTEVGILRVKESDRLEGIRTLVKAFGGTTELQG
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHEEEEECCCHHHHHHHHHHHHHCCCCEECC
EQLLIQPPRTPPAGFEMSSEGDHRLAMTAATLCVLSGTPLTLTGPECVEKSFPGFWRQLS
CEEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHEECCCCEEECCHHHHHHCCCHHHHHHH
RVGVRITDAG
HCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]