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The map label for this gene is htpX [H]

Identifier: 108563333

GI number: 108563333

Start: 956134

End: 957114

Strand: Direct

Name: htpX [H]

Synonym: HPAG1_0908

Alternate gene names: 108563333

Gene position: 956134-957114 (Clockwise)

Preceding gene: 108563332

Following gene: 108563334

Centisome position: 59.89

GC content: 39.65

Gene sequence:

>981_bases
ATGCGAGCGCGTTGCTCAAAGAAATCAAGCATGAGAAAGGAGAAAATAATGACGAATTTTGAAAAGATTATCGCGCAAAA
CAGACTCAAAACGAACGCGGTTTTAACCACTTATTGCGTGATTTTTGCTTTTATCGGGTTGTTGGTGGATGCTATTAGAA
TCAACGCTAATGATTTAGGCGTAGCCCTTTTTAAACTCATCACTTTTCAAATTTTTCCTACGATCACCACTATCATGTTT
TTAGCGGCTTTTGTCATTATTGTTGTTTGTATCCAAAATTTTAGCTCTATCATGTTAAGCGGTGATGAATACAAACTTAT
TGACACAAGCAAGGTTTTAAGCTCTAAAGAAAATCAAATCCATCGCCTTTTGTTAGAGCTTTTAGAAGAGGCTAAGCTTC
ATTTTGAGCCTAAACTTTATATCATTAACGCCCCTTACATGAACGCTTTTGCGAGCGGGTGGGATGAATCTAATTCCCTT
ATCGCTCTTACAAGCGCTTTAATAGAAAGGTTGGATAAAGATGAATTGAAAGCCGTGATCGCTCATGAGCTCAGCCACAT
ACGGCACAACGACATCCGCTTGACCATGTGCGTGGGGATTTTAAGCAATATCATGCTGTTAGTGGCTAATTTTAGCGTGT
ATTTTTTCATGGGGAATCGCAAGAATAGTGGGGCGAATTTAGCCCGAATGATTTTATTACTCTTACAGATCGTTTTGCCT
TTTTTAACGCTTATTTTGCAAATGTATTTGAGCCGCACACGAGAATACATGGCCGATAGCGGGGCGGCGTTTTTAATGCA
TGACAATAAGCCCATGATTAGAGCCTTACAAAAAATTTCTAACGACTACGCGAACAACGATTACAAGGGCATAGATCAGA
ACTCCACCCGATCGGCGGCTTATCTTTTTAACGCTGAAATGTTTAGCACCCACCCTAGCATTAAAAATCGTATCCAATCT
TTATCAAGGCGCGTGATTTAA

Upstream 100 bases:

>100_bases
TCTAGGCGGTTTTTTTGGGTGTTTGCAGAAAATGTAACTTCTCAATATATCAAAGAAAAAGCGCAATTTGAATTGGGATT
TTACTTGCCTAAAGGGAGTT

Downstream 100 bases:

>100_bases
ATGGAAAATTTTTTCAACCAATTTTTTGAAAATATCGGCGAAGATAAGAATAGAGAAGGTCTAAAAGAGACGCCTAAAAG
GGTTCAAGAATTATGGAAAT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRARCSKKSSMRKEKIMTNFEKIIAQNRLKTNAVLTTYCVIFAFIGLLVDAIRINANDLGVALFKLITFQIFPTITTIMF
LAAFVIIVVCIQNFSSIMLSGDEYKLIDTSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWDESNSL
IALTSALIERLDKDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLLLQIVLP
FLTLILQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYANNDYKGIDQNSTRSAAYLFNAEMFSTHPSIKNRIQS
LSRRVI

Sequences:

>Translated_326_residues
MRARCSKKSSMRKEKIMTNFEKIIAQNRLKTNAVLTTYCVIFAFIGLLVDAIRINANDLGVALFKLITFQIFPTITTIMF
LAAFVIIVVCIQNFSSIMLSGDEYKLIDTSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWDESNSL
IALTSALIERLDKDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLLLQIVLP
FLTLILQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYANNDYKGIDQNSTRSAAYLFNAEMFSTHPSIKNRIQS
LSRRVI
>Mature_326_residues
MRARCSKKSSMRKEKIMTNFEKIIAQNRLKTNAVLTTYCVIFAFIGLLVDAIRINANDLGVALFKLITFQIFPTITTIMF
LAAFVIIVVCIQNFSSIMLSGDEYKLIDTSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWDESNSL
IALTSALIERLDKDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLLLQIVLP
FLTLILQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYANNDYKGIDQNSTRSAAYLFNAEMFSTHPSIKNRIQS
LSRRVI

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=201, Percent_Identity=32.8358208955224, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 37122; Mature: 37122

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARCSKKSSMRKEKIMTNFEKIIAQNRLKTNAVLTTYCVIFAFIGLLVDAIRINANDLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VALFKLITFQIFPTITTIMFLAAFVIIVVCIQNFSSIMLSGDEYKLIDTSKVLSSKENQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCHHHHH
HRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWDESNSLIALTSALIERLDKDELKAVI
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHH
AHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLLLQIVLP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
FLTLILQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYANNDYKGIDQNSTRSAA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
YLFNAEMFSTHPSIKNRIQSLSRRVI
HEEEHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRARCSKKSSMRKEKIMTNFEKIIAQNRLKTNAVLTTYCVIFAFIGLLVDAIRINANDLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VALFKLITFQIFPTITTIMFLAAFVIIVVCIQNFSSIMLSGDEYKLIDTSKVLSSKENQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCHHHHH
HRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWDESNSLIALTSALIERLDKDELKAVI
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHH
AHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLLLQIVLP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
FLTLILQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYANNDYKGIDQNSTRSAA
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
YLFNAEMFSTHPSIKNRIQSLSRRVI
HEEEHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]