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The map label for this gene is mtnU [H]

Identifier: 108562736

GI number: 108562736

Start: 323277

End: 324155

Strand: Direct

Name: mtnU [H]

Synonym: HPAG1_0311

Alternate gene names: 108562736

Gene position: 323277-324155 (Clockwise)

Preceding gene: 108562735

Following gene: 108562737

Centisome position: 20.25

GC content: 41.52

Gene sequence:

>879_bases
TTGAAAACAAAAAATCCCGCCAAAAGAATCCTAAAAACCGCTGTGATTCAAATGCAATCCAAACCCTACGCCTTAAATGA
AAACCTGCAATTAGCGCTCAATCTCGCCAAAGAAGCCCACGACAAAGGCGCGAATCTCATTGTTTTACCGGAATTGTTTG
ATAGCGGTTATTGCGTGAATGATAAAGACACAGAGTTTGGGATAGATTTTAAAGCGATAGAGCATGGCAAGCTAAAAAAC
GAGTCGTTGAGTGCGTTAAGTAATTTTGCAAAGTCTAATAAAGTGCATCTAGTGGCGTGTAGCATTGAAAAAACGGATAA
AAAACTCTACGACAGCGCTTATATCATTCCACCAGAAGGCGGGATTTCTGGAAAACACCGCAAGATTTATTTGTGGGGCG
ATGAAAAATCGCGCTTTAGAAGGGGTAAAAAATACGAGGTTTTTACGCTGGATTTTGGGGATTTTAGCACAAAAGTGGGT
TTGCAAATTTGCTATGAAATCGGCTTTGGCGTGGGTGCGAATCTTTTAGCGTTACAAGGAGCTGAGGTTTTAATCTATCC
TAGCGCGTTTGGCAAGGCTAGGGCTTATAATTGGGATTTATTGAGCAAAGCTAGAGCGTTAGAAAATGGCTGTTTTGTGT
GCGCGTGCAATCATAGTGGGGAAGAAACTAACGCTCAATTAAAACAAACGCTAGAGTTTGCCGGCGATTCAAGAATCATC
GCGCCCAATGGGAAAATCATTGCGCAAGCCACTAAGCTTAATGAAGTCGTTATCGCTGAAATGGATTTAAACGAAGCGGC
ACTGCAACGCCAAAAAATCCCTTATTTACAAGATTTTGACACCAAACTCACCAAAAAGGGGTTTGGAAAACTCACTTAA

Upstream 100 bases:

>100_bases
ATAATGGTAAGTTTTGACACAAACTCCTATGGATTTTAACCCCTTTAATCCTCTTTTAATTTCTAATCCTATACAATAAA
AACAAAAATGGGAGTGGATC

Downstream 100 bases:

>100_bases
AAAGGAGCGATTATGGCAAAAGAAATTTTAGTGGCTTATGGCGTGGATATTGATGCGGTGGCTGGTTGGCTAGGGAGCTA
TGGTGGGGAGGATTCGCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHDKGANLIVLPELFDSGYCVNDKDTEFGIDFKAIEHGKLKN
ESLSALSNFAKSNKVHLVACSIEKTDKKLYDSAYIIPPEGGISGKHRKIYLWGDEKSRFRRGKKYEVFTLDFGDFSTKVG
LQICYEIGFGVGANLLALQGAEVLIYPSAFGKARAYNWDLLSKARALENGCFVCACNHSGEETNAQLKQTLEFAGDSRII
APNGKIIAQATKLNEVVIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT

Sequences:

>Translated_292_residues
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHDKGANLIVLPELFDSGYCVNDKDTEFGIDFKAIEHGKLKN
ESLSALSNFAKSNKVHLVACSIEKTDKKLYDSAYIIPPEGGISGKHRKIYLWGDEKSRFRRGKKYEVFTLDFGDFSTKVG
LQICYEIGFGVGANLLALQGAEVLIYPSAFGKARAYNWDLLSKARALENGCFVCACNHSGEETNAQLKQTLEFAGDSRII
APNGKIIAQATKLNEVVIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT
>Mature_292_residues
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHDKGANLIVLPELFDSGYCVNDKDTEFGIDFKAIEHGKLKN
ESLSALSNFAKSNKVHLVACSIEKTDKKLYDSAYIIPPEGGISGKHRKIYLWGDEKSRFRRGKKYEVFTLDFGDFSTKVG
LQICYEIGFGVGANLLALQGAEVLIYPSAFGKARAYNWDLLSKARALENGCFVCACNHSGEETNAQLKQTLEFAGDSRII
APNGKIIAQATKLNEVVIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=279, Percent_Identity=30.4659498207885, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI5031947, Length=283, Percent_Identity=27.5618374558304, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI297632348, Length=277, Percent_Identity=27.7978339350181, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI297632350, Length=283, Percent_Identity=27.5618374558304, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786412, Length=242, Percent_Identity=26.0330578512397, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17556280, Length=276, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323383, Length=279, Percent_Identity=29.3906810035842, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322335, Length=301, Percent_Identity=26.578073089701, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355835, Length=277, Percent_Identity=29.2418772563177, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17933642, Length=260, Percent_Identity=29.2307692307692, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 32391; Mature: 32391

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHDKGANLIVLPELFDSGYCVN
CCCCCHHHHHHHHHHHHHCCCCEEECCCCEEEEEHHHHHHCCCCCEEEEHHHCCCCCEEC
DKDTEFGIDFKAIEHGKLKNESLSALSNFAKSNKVHLVACSIEKTDKKLYDSAYIIPPEG
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHCCEEEECCCC
GISGKHRKIYLWGDEKSRFRRGKKYEVFTLDFGDFSTKVGLQICYEIGFGVGANLLALQG
CCCCCEEEEEEECCCHHHHHCCCCEEEEEEECCCCCHHHHHHEEEECCCCCCCCEEEECC
AEVLIYPSAFGKARAYNWDLLSKARALENGCFVCACNHSGEETNAQLKQTLEFAGDSRII
CEEEEEECCCCCCEECCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEE
APNGKIIAQATKLNEVVIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT
CCCCCEEEEEECCCEEEEEEECCCHHHHHHHCCCCHHHCCHHHHHCCCCCCC
>Mature Secondary Structure
MKTKNPAKRILKTAVIQMQSKPYALNENLQLALNLAKEAHDKGANLIVLPELFDSGYCVN
CCCCCHHHHHHHHHHHHHCCCCEEECCCCEEEEEHHHHHHCCCCCEEEEHHHCCCCCEEC
DKDTEFGIDFKAIEHGKLKNESLSALSNFAKSNKVHLVACSIEKTDKKLYDSAYIIPPEG
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHCCEEEECCCC
GISGKHRKIYLWGDEKSRFRRGKKYEVFTLDFGDFSTKVGLQICYEIGFGVGANLLALQG
CCCCCEEEEEEECCCHHHHHCCCCEEEEEEECCCCCHHHHHHEEEECCCCCCCCEEEECC
AEVLIYPSAFGKARAYNWDLLSKARALENGCFVCACNHSGEETNAQLKQTLEFAGDSRII
CEEEEEECCCCCCEECCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEE
APNGKIIAQATKLNEVVIAEMDLNEAALQRQKIPYLQDFDTKLTKKGFGKLT
CCCCCEEEEEECCCEEEEEEECCCHHHHHHHCCCCHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]