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The map label for this gene is lpsI [H]

Identifier: 103487604

GI number: 103487604

Start: 2229553

End: 2230263

Strand: Direct

Name: lpsI [H]

Synonym: Sala_2123

Alternate gene names: 103487604

Gene position: 2229553-2230263 (Clockwise)

Preceding gene: 103487602

Following gene: 103487605

Centisome position: 66.65

GC content: 63.85

Gene sequence:

>711_bases
ATGGCGAACAAGCTTTATCCCGACGCCGCTGCCGCGCTCGACGGTCTGCTCTTTGACGGGATGCAGATTTGCGCGGGCGG
CTTTGGCCTGTGCGGCATCCCCGAACGGTTGATCGACGCGGTCCGCGACGCGGGGGTCAAGGATCTGACCATCGCGAGCA
ACAACGCCGGGATCGACGGCGAAGGACTCGGCAAGCTGCTACGCACGCGGCAGGTCAAGAAGATGATCTCGTCCTACGTC
GGCGAGAACAAGGAGTTCGAGCGGCAATATCTGGCGGGCGAGCTGGAGGTCGAGTTCTGTCCGCAGGGGACGCTCGCCGA
ACGCTGCCGCGCGGGCGGCGCGGGCATTCCGGGCTTCTATACCAGAACCGGCGTCGGCACGCTCGTCGCCGAGGGCAAGG
AAGTGAAGAGTTTCGACGGGCAGGATTATATCCTGGAGCGCGGCATCTTCGCAGACCTCGCGATCATCAAAGGGTGGAAA
GCCGACGAAAGCGGCAACCTGATTTTCCGCAAGACCGCGCGCAATTTCAACCAGCCGATGGCGACCGCGGCCAGGATCTG
CGTCGCCGAGGTCGAGGAAATCGTGCCTACGGGCAGCCTCGACCCCGACTGCATCCACCTGCCCGGCATCTATGTGAAGC
GGATGATCGTCGGCGCGCCGTACGACAAGAAGATCGAGTTCCGCACCGTTCGCCCGAGGGAGACCGCCTGA

Upstream 100 bases:

>100_bases
GATAGACATAATTTATCCATAATCGAAAATTAGAACAATTAGAATTGATGGATTATTTGCGCCAAGGTCGCGCCCGCACC
CCCAGCCAGGAGGCCGTTGA

Downstream 100 bases:

>100_bases
TGCCCTGGACCCGCGACGATATGGCGGCGCGCGCCGCAAAAGAGCTGCAGGACGGCTATTATGTCAACCTCGGCATCGGC
ATCCCGACGCTGGTGGCGAA

Product: 3-oxoacid CoA-transferase, subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MANKLYPDAAAALDGLLFDGMQICAGGFGLCGIPERLIDAVRDAGVKDLTIASNNAGIDGEGLGKLLRTRQVKKMISSYV
GENKEFERQYLAGELEVEFCPQGTLAERCRAGGAGIPGFYTRTGVGTLVAEGKEVKSFDGQDYILERGIFADLAIIKGWK
ADESGNLIFRKTARNFNQPMATAARICVAEVEEIVPTGSLDPDCIHLPGIYVKRMIVGAPYDKKIEFRTVRPRETA

Sequences:

>Translated_236_residues
MANKLYPDAAAALDGLLFDGMQICAGGFGLCGIPERLIDAVRDAGVKDLTIASNNAGIDGEGLGKLLRTRQVKKMISSYV
GENKEFERQYLAGELEVEFCPQGTLAERCRAGGAGIPGFYTRTGVGTLVAEGKEVKSFDGQDYILERGIFADLAIIKGWK
ADESGNLIFRKTARNFNQPMATAARICVAEVEEIVPTGSLDPDCIHLPGIYVKRMIVGAPYDKKIEFRTVRPRETA
>Mature_235_residues
ANKLYPDAAAALDGLLFDGMQICAGGFGLCGIPERLIDAVRDAGVKDLTIASNNAGIDGEGLGKLLRTRQVKKMISSYVG
ENKEFERQYLAGELEVEFCPQGTLAERCRAGGAGIPGFYTRTGVGTLVAEGKEVKSFDGQDYILERGIFADLAIIKGWKA
DESGNLIFRKTARNFNQPMATAARICVAEVEEIVPTGSLDPDCIHLPGIYVKRMIVGAPYDKKIEFRTVRPRETA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=56.6801619433198, Blast_Score=278, Evalue=4e-75,
Organism=Homo sapiens, GI11545841, Length=249, Percent_Identity=51.4056224899598, Blast_Score=234, Evalue=5e-62,
Organism=Escherichia coli, GI1788551, Length=203, Percent_Identity=45.320197044335, Blast_Score=184, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=246, Percent_Identity=50.8130081300813, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=53.6, Blast_Score=264, Evalue=4e-71,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=53.6, Blast_Score=264, Evalue=4e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25582; Mature: 25451

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKLYPDAAAALDGLLFDGMQICAGGFGLCGIPERLIDAVRDAGVKDLTIASNNAGIDG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCH
EGLGKLLRTRQVKKMISSYVGENKEFERQYLAGELEVEFCPQGTLAERCRAGGAGIPGFY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCH
TRTGVGTLVAEGKEVKSFDGQDYILERGIFADLAIIKGWKADESGNLIFRKTARNFNQPM
HHCCCHHHHHCCCHHHCCCCCHHHHHCCHHHHHHHHCCCCCCCCCCEEEEECHHCCCCHH
ATAARICVAEVEEIVPTGSLDPDCIHLPGIYVKRMIVGAPYDKKIEFRTVRPRETA
HHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
ANKLYPDAAAALDGLLFDGMQICAGGFGLCGIPERLIDAVRDAGVKDLTIASNNAGIDG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCH
EGLGKLLRTRQVKKMISSYVGENKEFERQYLAGELEVEFCPQGTLAERCRAGGAGIPGFY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCH
TRTGVGTLVAEGKEVKSFDGQDYILERGIFADLAIIKGWKADESGNLIFRKTARNFNQPM
HHCCCHHHHHCCCHHHCCCCCHHHHHCCHHHHHHHHCCCCCCCCCCEEEEECHHCCCCHH
ATAARICVAEVEEIVPTGSLDPDCIHLPGIYVKRMIVGAPYDKKIEFRTVRPRETA
HHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]