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The map label for this gene is yafV [C]

Identifier: 103487451

GI number: 103487451

Start: 2075920

End: 2076780

Strand: Direct

Name: yafV [C]

Synonym: Sala_1967

Alternate gene names: 103487451

Gene position: 2075920-2076780 (Clockwise)

Preceding gene: 103487449

Following gene: 103487452

Centisome position: 62.06

GC content: 67.13

Gene sequence:

>861_bases
ATGACCGGCCCCGATGACGACCCGCTCGCTGCGCTTGTCCAGATGACCAGCGGGATTGACCCGGCCGCCAATCTGGCGGT
GATCGACCGCGCGATGGGCGAAGCGGCGGCGCATGGCGCGGCGATGGCCTTTCTACCCGAAATGTCGTTGTTGCTCGACC
GCGATCGCGCGCGTTCGGCGGCGCATATCGCAACCGAAGCACAAAGCCCGTGGCCGTCGGCGTTGCAGGAGATGGCGCGG
CGGCATGCCATATGGCTGCATTCGGGGTCGATGCCGCTGCTCGCCGACGATGGCCAACGGCGCGTCAACCGCAGCCATGT
CATCGCCGCCGATGGCAGAATCCGCGCGCGGTACGACAAGATCCACATGTTCGACGTGCAGCTGCCATCGGGCGAGAATT
GGCAGGAATCGGCGGCTTATGCGGGGGGCGACGCGCTCTGCATCGTCGATACGCCGCTCGGCCGGCTGGGCCTTAGCATC
TGTTACGACCTGCGCTTTCCCGAACTCTATCGCGCGCTTGTCGACAGCGGCGCGACGCTGATCGCGATCCCCGCCGCCTT
CACCGTGCCGACGGGCGAGGCGCATTGGCACGTCCTGCTCCGCGCGCGTGCGATCGAAACCGCATGCCATGTCGTTGCCG
CGGCGCAATGCGGCCAGCACACCGACGGCCGCACAACCTATGGACACAGCCTGGCGGTCGATCCGTGGGGTGCGATCCTC
GCCGATGCCGCGCGGAGCGATGAAGCGAATCAGAAGGGTTATTCGCTGACGATCGTGCCGATCGACGCGACCGCGGCAAC
CAGGGCGCGCGCGGCAATTCCGCTGAGCCGGTCGCGCGCGATTCGCCGCATCGACCTTTAG

Upstream 100 bases:

>100_bases
GCTGGATCAGACGACATTGGGCTATCTTATCGCCTTCGAACCTTGCTGGCCACTGAACTGTCGGCTTGTCGGCAGTGGCG
CATGGCATTAGCCAGACGAT

Downstream 100 bases:

>100_bases
GGCGGATTGGCATTATTTCGCCCGTCATTGCGGCGAAGGGCGGAATCTCACCCTCGCAATCTGACGCAGCGTCGATATTC
CCGCCTTCGCCGGAATGAAG

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTGPDDDPLAALVQMTSGIDPAANLAVIDRAMGEAAAHGAAMAFLPEMSLLLDRDRARSAAHIATEAQSPWPSALQEMAR
RHAIWLHSGSMPLLADDGQRRVNRSHVIAADGRIRARYDKIHMFDVQLPSGENWQESAAYAGGDALCIVDTPLGRLGLSI
CYDLRFPELYRALVDSGATLIAIPAAFTVPTGEAHWHVLLRARAIETACHVVAAAQCGQHTDGRTTYGHSLAVDPWGAIL
ADAARSDEANQKGYSLTIVPIDATAATRARAAIPLSRSRAIRRIDL

Sequences:

>Translated_286_residues
MTGPDDDPLAALVQMTSGIDPAANLAVIDRAMGEAAAHGAAMAFLPEMSLLLDRDRARSAAHIATEAQSPWPSALQEMAR
RHAIWLHSGSMPLLADDGQRRVNRSHVIAADGRIRARYDKIHMFDVQLPSGENWQESAAYAGGDALCIVDTPLGRLGLSI
CYDLRFPELYRALVDSGATLIAIPAAFTVPTGEAHWHVLLRARAIETACHVVAAAQCGQHTDGRTTYGHSLAVDPWGAIL
ADAARSDEANQKGYSLTIVPIDATAATRARAAIPLSRSRAIRRIDL
>Mature_285_residues
TGPDDDPLAALVQMTSGIDPAANLAVIDRAMGEAAAHGAAMAFLPEMSLLLDRDRARSAAHIATEAQSPWPSALQEMARR
HAIWLHSGSMPLLADDGQRRVNRSHVIAADGRIRARYDKIHMFDVQLPSGENWQESAAYAGGDALCIVDTPLGRLGLSIC
YDLRFPELYRALVDSGATLIAIPAAFTVPTGEAHWHVLLRARAIETACHVVAAAQCGQHTDGRTTYGHSLAVDPWGAILA
DAARSDEANQKGYSLTIVPIDATAATRARAAIPLSRSRAIRRIDL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=276, Percent_Identity=38.4057971014493, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI297632350, Length=276, Percent_Identity=38.4057971014493, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI5031947, Length=276, Percent_Identity=38.4057971014493, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI9910460, Length=269, Percent_Identity=32.7137546468402, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI297632346, Length=194, Percent_Identity=35.0515463917526, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1786412, Length=235, Percent_Identity=29.7872340425532, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17556280, Length=238, Percent_Identity=41.5966386554622, Blast_Score=183, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6322335, Length=298, Percent_Identity=32.5503355704698, Blast_Score=156, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323383, Length=277, Percent_Identity=31.4079422382672, Blast_Score=145, Evalue=6e-36,
Organism=Drosophila melanogaster, GI17933642, Length=247, Percent_Identity=38.0566801619433, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI21355835, Length=282, Percent_Identity=26.9503546099291, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30666; Mature: 30535

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00141 ASP_PROTEASE ; PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPDDDPLAALVQMTSGIDPAANLAVIDRAMGEAAAHGAAMAFLPEMSLLLDRDRARSA
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHH
AHIATEAQSPWPSALQEMARRHAIWLHSGSMPLLADDGQRRVNRSHVIAADGRIRARYDK
HHHHHCCCCCCHHHHHHHHHHCEEEEECCCCCEEECCCHHHCCCCEEEEECCEEEEEEEE
IHMFDVQLPSGENWQESAAYAGGDALCIVDTPLGRLGLSICYDLRFPELYRALVDSGATL
EEEEEEECCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHEEECCCHHHHHHHHHCCCEE
IAIPAAFTVPTGEAHWHVLLRARAIETACHVVAAAQCGQHTDGRTTYGHSLAVDPWGAIL
EEECCEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHH
ADAARSDEANQKGYSLTIVPIDATAATRARAAIPLSRSRAIRRIDL
HHHHCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCHHHCCHHCCCC
>Mature Secondary Structure 
TGPDDDPLAALVQMTSGIDPAANLAVIDRAMGEAAAHGAAMAFLPEMSLLLDRDRARSA
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHH
AHIATEAQSPWPSALQEMARRHAIWLHSGSMPLLADDGQRRVNRSHVIAADGRIRARYDK
HHHHHCCCCCCHHHHHHHHHHCEEEEECCCCCEEECCCHHHCCCCEEEEECCEEEEEEEE
IHMFDVQLPSGENWQESAAYAGGDALCIVDTPLGRLGLSICYDLRFPELYRALVDSGATL
EEEEEEECCCCCCHHHHHHCCCCCEEEEEECCHHHHHHHHEEECCCHHHHHHHHHCCCEE
IAIPAAFTVPTGEAHWHVLLRARAIETACHVVAAAQCGQHTDGRTTYGHSLAVDPWGAIL
EEECCEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHH
ADAARSDEANQKGYSLTIVPIDATAATRARAAIPLSRSRAIRRIDL
HHHHCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]