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The map label for this gene is 103487309

Identifier: 103487309

GI number: 103487309

Start: 1921903

End: 1922271

Strand: Direct

Name: 103487309

Synonym: Sala_1825

Alternate gene names: NA

Gene position: 1921903-1922271 (Clockwise)

Preceding gene: 103487304

Following gene: 103487311

Centisome position: 57.45

GC content: 62.87

Gene sequence:

>369_bases
ATGTCATCGCGCTCTAGACTTGTCGCTCATCGCGCCCTTTCTTATGGCGACCGCACGGCATTGACCAGCGGGAGAAAAAC
CATGGTGCAGAAACTCGACGATGCGCAGCGCAGCGCGCTGCTCGCCCGCTTCCCCCAATGGACGCACGACCCGGTGCGCG
ATGCGATCACGCGGCAGTTCCGGTTCGACGATTTCGCGCAGGCCTTCGGCTTCATGGCGAGCGTCGCGATCGTCGCCGAA
AAGCTGGACCATCATCCCGAATGGTCGAACGTCTATAACCGCGTCGACGTGCTGCTGACGACGCACGATGCCAACGGACT
TTCGGAGCGCGACGCGAAGCTCGCGGAGGCGATCGAGGCGCTGCTCTGA

Upstream 100 bases:

>100_bases
CCGCCGGACAGCGGCGCGTCTCTGGTCCGGGCAACCAGCCCGTCCTGCGAGACGCTTCTTGCCGACGAACTTCAGGGGGC
AATCACGGTGGGTCAATATC

Downstream 100 bases:

>100_bases
GCCTCGATCAGAGGATTTCGCGCACCTTGTCCTGCGGTCGGCACAGCCGCACGCCCTTTTCGGTTTCGACGAAGGGGCGC
TCGACATAGGCGGGATTCGC

Product: transcriptional coactivator/pterin dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MSSRSRLVAHRALSYGDRTALTSGRKTMVQKLDDAQRSALLARFPQWTHDPVRDAITRQFRFDDFAQAFGFMASVAIVAE
KLDHHPEWSNVYNRVDVLLTTHDANGLSERDAKLAEAIEALL

Sequences:

>Translated_122_residues
MSSRSRLVAHRALSYGDRTALTSGRKTMVQKLDDAQRSALLARFPQWTHDPVRDAITRQFRFDDFAQAFGFMASVAIVAE
KLDHHPEWSNVYNRVDVLLTTHDANGLSERDAKLAEAIEALL
>Mature_121_residues
SSRSRLVAHRALSYGDRTALTSGRKTMVQKLDDAQRSALLARFPQWTHDPVRDAITRQFRFDDFAQAFGFMASVAIVAEK
LDHHPEWSNVYNRVDVLLTTHDANGLSERDAKLAEAIEALL

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI4557831, Length=92, Percent_Identity=54.3478260869565, Blast_Score=99, Evalue=9e-22,
Organism=Homo sapiens, GI134133240, Length=118, Percent_Identity=42.3728813559322, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533705, Length=110, Percent_Identity=46.3636363636364, Blast_Score=101, Evalue=9e-23,
Organism=Drosophila melanogaster, GI45549100, Length=97, Percent_Identity=47.4226804123711, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001533 [H]

Pfam domain/function: PF01329 Pterin_4a [H]

EC number: =4.2.1.96 [H]

Molecular weight: Translated: 13784; Mature: 13652

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRSRLVAHRALSYGDRTALTSGRKTMVQKLDDAQRSALLARFPQWTHDPVRDAITRQF
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RFDDFAQAFGFMASVAIVAEKLDHHPEWSNVYNRVDVLLTTHDANGLSERDAKLAEAIEA
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHH
LL
HC
>Mature Secondary Structure 
SSRSRLVAHRALSYGDRTALTSGRKTMVQKLDDAQRSALLARFPQWTHDPVRDAITRQF
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RFDDFAQAFGFMASVAIVAEKLDHHPEWSNVYNRVDVLLTTHDANGLSERDAKLAEAIEA
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHH
LL
HC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA