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The map label for this gene is lptD [H]

Identifier: 103487247

GI number: 103487247

Start: 1856955

End: 1859258

Strand: Direct

Name: lptD [H]

Synonym: Sala_1762

Alternate gene names: 103487247

Gene position: 1856955-1859258 (Clockwise)

Preceding gene: 103487243

Following gene: 103487249

Centisome position: 55.51

GC content: 65.8

Gene sequence:

>2304_bases
ATGAGCTGGTCTTTGTTCCCACACGCCGCGCGCGCGCGCCCGATCTGGCTCGCGACGGCGAGCGGTCTGGCGCTGGCGGC
GAGCCCGGTGCTGGCGCAGAGCGAGCCGAATCGGACCGCGGCGCCGGAGATTGCGGCTGAGCCCGACCTGCAAACCCCGG
ACCTCGCACCCGCACCCGCCGATGCGCCCGAAACGGCGGGGGAGCAGCAGATCGGTTTTGCCGCCGACAACCTCCATTAC
GACAGCGAGGCCGATGTCGTCGTCGCCGAGGGCAATGTGCTGATGAACCGCGACGCGATTGCGATGCGCGCCGACAAGGT
GACGTGGAATCGCACGACGGGGCAGGTCGTCGCCGAAGGCAATGTGATGATCCGCAACCCGGAGGGCGACACCGCCTATG
GCGAGCGAATCGAGCTGACCGACAGCCTGCGCGACGGGGTGGTCGAAAATCTGCTCGTCGTGCTCGACAATGGCGCGCGC
CTTGCCGCGGTCAGGGGCACGCGCTTCGACAATGGCAATATCGAACTGGAGAACGCCGCCTATACCCCCTGCCCGGTCGA
GGATGAGTCGGGGTGTCCCAAGAATCCGAGCTGGCAGATCCGCGCGGTCCGCGTGATGTACGACCGTGAAAAGAACAAGA
TCCGGTACAAGGGCGCGCGCGTCGAGATTTTCGGCCTGCCGCTGATCCCGCTGCCGGGGCTCAGCCATCCTGCGAACCGC
GAGGCGGGCAGCGGCATCCTGGTTCCCGAAATCCGCCTCGACCGCAGCAACGGGTTCGAGGTTGCGGTGCCCTATTATCT
GCGCCTTGCCCCCGACCGCGACGTGACGATCACGCCGCACCTCTACACCGACGCGGCGCCGATGCTGGAAGGCGAGTTTC
GCGCGCTGACCGACATCGGATCATTCCGCATCAACGGCTATGCGACCTATGGTTCGCTCGTCCCGCTGGTCGGCGAAGAC
CCCGACCGCCAGAAACGCTTTCGCGGCTATCTCGAAAGCGCGGGCCGCTTCCAGTTCGATCCGCGCTGGAGCCTTAGCTA
TTCGGGCCGCATCGCGACCGACCGCACCTTCATGCGGCGCTACGACATCAGCCGCGACGACCGGCTGCGCTCGACCTTCG
AGCTCGAGCGGATCGGCGGCAATTCCTATCTGTCGATCGCGGGCTGGGCGACACAGACGCTGCGCGTCAACGATGTGCAG
GGGCAACAGCCGATTGCGCTGCCGATCATCGATTATCGCCAGCGGCTCGACGATCCGATCTTCGGCGGGCAGTTCGAGCT
GCAACTCAACACGCTTGCGATCGGTCGCACCGCGGGGCAGGACACGCAGCGCGCCTTTGCCGGGGCACAGTGGAACCTGC
GCGGACTGACCGGGCTGGGGCAGGAAGTCACGCTGACCGCAATGGTGCGCGGCGACGTCTATCACAGCGACGAAAATCTG
CTGACCGCCATCCCCGGCTATCGCGGCAAGTCGGGATGGCAGGCGCGCGGCATCGCGGCGATCGCCGCCGACATGCGCTG
GCCCTTCATCGGCGAATTCGCAGGCGGAACGCAGACGCTGACCCCGCGCGTCCAGGTCGTCGCGACGCCGCCGATCAAGA
ATCTCGACATTCCTAACGAGGATTCGCGCGCCTTCGACCTCGAGGACAGCAATCTTTTCGCGATCAACCGCTTCAACGGC
CACGACCGGTTCGAGGACGGCGCGCGCGTCACCTATGGCGTCGAGTGGAATTACAGCCGCCCGGGGTTCAACATCAACAG
CATCGTCGGGCAAAGCTATCGGCTGACCGACAAGCCCAGCCTGTTTCCCGATGGCACCGGACTCACCGACCGCACCTCGG
ACATCGTCGGGCGAACGACGATTGCCTACAAGGATTTCCTGCGTTTCACCCACCGCTACCGGCTCGACAAGGACAATCTG
GCGGTGCGGCGCAACGAGTTCGACGCGACGATCGGCAACCGCTCGACCTATGCCGTGCTCGGCTATTCGCGGCTCAACCG
CGACATATTGCTGCTCGGCGAGGATTTGCAGGACCGCGAGGAGGTGCGCGCGGGCGGGCGCATCGCGGTGGCGCGGAACT
GGTCGATCTTCGGATCGGCGATCGTCGACCTGACCAACCAGGCCGACGATCCGCTGAGCAGCGCCGACGGCTTCGAACCG
ATCCGCCACCGGCTCGGCATCGCCTATGACGACGAATGCCTGTCGATCGCGCTCACCTGGCGCCGCGATTATGCCGACAC
GGGCGACGCACGGCGCGGGAACAGTTTTTCGTTCCGCATCGCCTTCCGCAACCTGGGGTTCTGA

Upstream 100 bases:

>100_bases
ACGTGGCGGACCGATAGGGGTTTCGCCTGCGAGTTGCAAAAACAAAGCGGCCGGTCCAAGCCGGGAAACGTCGATATAGG
GTTCGGGACAAAGGGATTAA

Downstream 100 bases:

>100_bases
GGTTTCGGCTGCGGCCACCTAATGCTCCCCATCGACTTGCGATGGGGAGGGGGACCGCCGCCGCAGGCGGTGGTGGAGGG
GTAGCAACGTCCGCGTAATG

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 767; Mature: 766

Protein sequence:

>767_residues
MSWSLFPHAARARPIWLATASGLALAASPVLAQSEPNRTAAPEIAAEPDLQTPDLAPAPADAPETAGEQQIGFAADNLHY
DSEADVVVAEGNVLMNRDAIAMRADKVTWNRTTGQVVAEGNVMIRNPEGDTAYGERIELTDSLRDGVVENLLVVLDNGAR
LAAVRGTRFDNGNIELENAAYTPCPVEDESGCPKNPSWQIRAVRVMYDREKNKIRYKGARVEIFGLPLIPLPGLSHPANR
EAGSGILVPEIRLDRSNGFEVAVPYYLRLAPDRDVTITPHLYTDAAPMLEGEFRALTDIGSFRINGYATYGSLVPLVGED
PDRQKRFRGYLESAGRFQFDPRWSLSYSGRIATDRTFMRRYDISRDDRLRSTFELERIGGNSYLSIAGWATQTLRVNDVQ
GQQPIALPIIDYRQRLDDPIFGGQFELQLNTLAIGRTAGQDTQRAFAGAQWNLRGLTGLGQEVTLTAMVRGDVYHSDENL
LTAIPGYRGKSGWQARGIAAIAADMRWPFIGEFAGGTQTLTPRVQVVATPPIKNLDIPNEDSRAFDLEDSNLFAINRFNG
HDRFEDGARVTYGVEWNYSRPGFNINSIVGQSYRLTDKPSLFPDGTGLTDRTSDIVGRTTIAYKDFLRFTHRYRLDKDNL
AVRRNEFDATIGNRSTYAVLGYSRLNRDILLLGEDLQDREEVRAGGRIAVARNWSIFGSAIVDLTNQADDPLSSADGFEP
IRHRLGIAYDDECLSIALTWRRDYADTGDARRGNSFSFRIAFRNLGF

Sequences:

>Translated_767_residues
MSWSLFPHAARARPIWLATASGLALAASPVLAQSEPNRTAAPEIAAEPDLQTPDLAPAPADAPETAGEQQIGFAADNLHY
DSEADVVVAEGNVLMNRDAIAMRADKVTWNRTTGQVVAEGNVMIRNPEGDTAYGERIELTDSLRDGVVENLLVVLDNGAR
LAAVRGTRFDNGNIELENAAYTPCPVEDESGCPKNPSWQIRAVRVMYDREKNKIRYKGARVEIFGLPLIPLPGLSHPANR
EAGSGILVPEIRLDRSNGFEVAVPYYLRLAPDRDVTITPHLYTDAAPMLEGEFRALTDIGSFRINGYATYGSLVPLVGED
PDRQKRFRGYLESAGRFQFDPRWSLSYSGRIATDRTFMRRYDISRDDRLRSTFELERIGGNSYLSIAGWATQTLRVNDVQ
GQQPIALPIIDYRQRLDDPIFGGQFELQLNTLAIGRTAGQDTQRAFAGAQWNLRGLTGLGQEVTLTAMVRGDVYHSDENL
LTAIPGYRGKSGWQARGIAAIAADMRWPFIGEFAGGTQTLTPRVQVVATPPIKNLDIPNEDSRAFDLEDSNLFAINRFNG
HDRFEDGARVTYGVEWNYSRPGFNINSIVGQSYRLTDKPSLFPDGTGLTDRTSDIVGRTTIAYKDFLRFTHRYRLDKDNL
AVRRNEFDATIGNRSTYAVLGYSRLNRDILLLGEDLQDREEVRAGGRIAVARNWSIFGSAIVDLTNQADDPLSSADGFEP
IRHRLGIAYDDECLSIALTWRRDYADTGDARRGNSFSFRIAFRNLGF
>Mature_766_residues
SWSLFPHAARARPIWLATASGLALAASPVLAQSEPNRTAAPEIAAEPDLQTPDLAPAPADAPETAGEQQIGFAADNLHYD
SEADVVVAEGNVLMNRDAIAMRADKVTWNRTTGQVVAEGNVMIRNPEGDTAYGERIELTDSLRDGVVENLLVVLDNGARL
AAVRGTRFDNGNIELENAAYTPCPVEDESGCPKNPSWQIRAVRVMYDREKNKIRYKGARVEIFGLPLIPLPGLSHPANRE
AGSGILVPEIRLDRSNGFEVAVPYYLRLAPDRDVTITPHLYTDAAPMLEGEFRALTDIGSFRINGYATYGSLVPLVGEDP
DRQKRFRGYLESAGRFQFDPRWSLSYSGRIATDRTFMRRYDISRDDRLRSTFELERIGGNSYLSIAGWATQTLRVNDVQG
QQPIALPIIDYRQRLDDPIFGGQFELQLNTLAIGRTAGQDTQRAFAGAQWNLRGLTGLGQEVTLTAMVRGDVYHSDENLL
TAIPGYRGKSGWQARGIAAIAADMRWPFIGEFAGGTQTLTPRVQVVATPPIKNLDIPNEDSRAFDLEDSNLFAINRFNGH
DRFEDGARVTYGVEWNYSRPGFNINSIVGQSYRLTDKPSLFPDGTGLTDRTSDIVGRTTIAYKDFLRFTHRYRLDKDNLA
VRRNEFDATIGNRSTYAVLGYSRLNRDILLLGEDLQDREEVRAGGRIAVARNWSIFGSAIVDLTNQADDPLSSADGFEPI
RHRLGIAYDDECLSIALTWRRDYADTGDARRGNSFSFRIAFRNLGF

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=141, Percent_Identity=30.4964539007092, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 85173; Mature: 85042

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWSLFPHAARARPIWLATASGLALAASPVLAQSEPNRTAAPEIAAEPDLQTPDLAPAPA
CCCCCCCCCCCCCEEEEEECCCCEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAPETAGEQQIGFAADNLHYDSEADVVVAEGNVLMNRDAIAMRADKVTWNRTTGQVVAEG
CCCCCCCCCCCCEEECCCCCCCCCCEEEECCCEEECCCCEEEEECCEEEECCCCEEEEEC
NVMIRNPEGDTAYGERIELTDSLRDGVVENLLVVLDNGARLAAVRGTRFDNGNIELENAA
CEEEECCCCCCCCCCEEEEHHHHHHHHHHEEEEEEECCCEEEEEECCEECCCCEEECCCC
YTPCPVEDESGCPKNPSWQIRAVRVMYDREKNKIRYKGARVEIFGLPLIPLPGLSHPANR
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEECCEEEEEECCCCCCCCCCCCCCC
EAGSGILVPEIRLDRSNGFEVAVPYYLRLAPDRDVTITPHLYTDAAPMLEGEFRALTDIG
CCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCEEECCEEECCCCCCCCCCHHEEECCC
SFRINGYATYGSLVPLVGEDPDRQKRFRGYLESAGRFQFDPRWSLSYSGRIATDRTFMRR
CEEEEEEEECCCEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCEEECCEEECCHHHHHH
YDISRDDRLRSTFELERIGGNSYLSIAGWATQTLRVNDVQGQQPIALPIIDYRQRLDDPI
HCCCCCHHHHHEEEEEECCCCCEEEEEECEEEEEEEECCCCCCCEEEEHHHHHHHCCCCC
FGGQFELQLNTLAIGRTAGQDTQRAFAGAQWNLRGLTGLGQEVTLTAMVRGDVYHSDENL
CCCEEEEEEEEEEEECCCCCCHHHHHCCCCEEECCCCCCCCCEEEEEEEECCEEECCCCE
LTAIPGYRGKSGWQARGIAAIAADMRWPFIGEFAGGTQTLTPRVQVVATPPIKNLDIPNE
EEECCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCEEECCEEEEEECCCCCCCCCCCC
DSRAFDLEDSNLFAINRFNGHDRFEDGARVTYGVEWNYSRPGFNINSIVGQSYRLTDKPS
CCCEEECCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCHHHHCCCCEEECCCCC
LFPDGTGLTDRTSDIVGRTTIAYKDFLRFTHRYRLDKDNLAVRRNEFDATIGNRSTYAVL
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCCCEEEEE
GYSRLNRDILLLGEDLQDREEVRAGGRIAVARNWSIFGSAIVDLTNQADDPLSSADGFEP
EHHHCCCEEEEECCCCCCHHHHHCCCEEEEEECCCCHHHHEEECCCCCCCCCCCCCCCHH
IRHRLGIAYDDECLSIALTWRRDYADTGDARRGNSFSFRIAFRNLGF
HHHHCCCEECCCEEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
SWSLFPHAARARPIWLATASGLALAASPVLAQSEPNRTAAPEIAAEPDLQTPDLAPAPA
CCCCCCCCCCCCEEEEEECCCCEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAPETAGEQQIGFAADNLHYDSEADVVVAEGNVLMNRDAIAMRADKVTWNRTTGQVVAEG
CCCCCCCCCCCCEEECCCCCCCCCCEEEECCCEEECCCCEEEEECCEEEECCCCEEEEEC
NVMIRNPEGDTAYGERIELTDSLRDGVVENLLVVLDNGARLAAVRGTRFDNGNIELENAA
CEEEECCCCCCCCCCEEEEHHHHHHHHHHEEEEEEECCCEEEEEECCEECCCCEEECCCC
YTPCPVEDESGCPKNPSWQIRAVRVMYDREKNKIRYKGARVEIFGLPLIPLPGLSHPANR
CCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEECCEEEEEECCCCCCCCCCCCCCC
EAGSGILVPEIRLDRSNGFEVAVPYYLRLAPDRDVTITPHLYTDAAPMLEGEFRALTDIG
CCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCEEECCEEECCCCCCCCCCHHEEECCC
SFRINGYATYGSLVPLVGEDPDRQKRFRGYLESAGRFQFDPRWSLSYSGRIATDRTFMRR
CEEEEEEEECCCEEEECCCCCCHHHHHHHHHHCCCCEECCCCCCEEECCEEECCHHHHHH
YDISRDDRLRSTFELERIGGNSYLSIAGWATQTLRVNDVQGQQPIALPIIDYRQRLDDPI
HCCCCCHHHHHEEEEEECCCCCEEEEEECEEEEEEEECCCCCCCEEEEHHHHHHHCCCCC
FGGQFELQLNTLAIGRTAGQDTQRAFAGAQWNLRGLTGLGQEVTLTAMVRGDVYHSDENL
CCCEEEEEEEEEEEECCCCCCHHHHHCCCCEEECCCCCCCCCEEEEEEEECCEEECCCCE
LTAIPGYRGKSGWQARGIAAIAADMRWPFIGEFAGGTQTLTPRVQVVATPPIKNLDIPNE
EEECCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCEEECCEEEEEECCCCCCCCCCCC
DSRAFDLEDSNLFAINRFNGHDRFEDGARVTYGVEWNYSRPGFNINSIVGQSYRLTDKPS
CCCEEECCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCHHHHCCCCEEECCCCC
LFPDGTGLTDRTSDIVGRTTIAYKDFLRFTHRYRLDKDNLAVRRNEFDATIGNRSTYAVL
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEECCCCCEEEEE
GYSRLNRDILLLGEDLQDREEVRAGGRIAVARNWSIFGSAIVDLTNQADDPLSSADGFEP
EHHHCCCEEEEECCCCCCHHHHHCCCEEEEEECCCCHHHHEEECCCCCCCCCCCCCCCHH
IRHRLGIAYDDECLSIALTWRRDYADTGDARRGNSFSFRIAFRNLGF
HHHHCCCEECCCEEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA