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The map label for this gene is mreB [H]

Identifier: 103487112

GI number: 103487112

Start: 1707402

End: 1708448

Strand: Direct

Name: mreB [H]

Synonym: Sala_1627

Alternate gene names: 103487112

Gene position: 1707402-1708448 (Clockwise)

Preceding gene: 103487110

Following gene: 103487113

Centisome position: 51.04

GC content: 65.43

Gene sequence:

>1047_bases
ATGTCCTTCTTTTCCCGCTGGTTCAAATTCAATTCGCAAGACATGGCCATCGACCTCGGCACCGCGAACACGGTCGTCTA
TGTGCGCGGCAAGGGCATCGTGCTCAACGAACCTTCGGTCGTCGCGGTCGAGACGCTGAACGGGATCAAGCGGGTCAAGG
CGGTCGGCGACGACGCCAAGCTGATGATGGGCAAGACCCCCGACAGCATCGAGGCGATCCGCCCGCTGCGCGATGGCGTG
ATTGCCGACATCGACGTCGCCGAACAGATGATCAAGCATTTCATCACCAAGGTGCACGGCGGCAAGCCCAACGCCTTCCG
CAGCCCCGAAATCGTCATCTGCGTTCCCTCGGGCTCGACGAGCGTCGAACGCCGTGCGATCCGCGACGCCGCATCGAACG
CGGGCGCGAGCGAAGTGTGGCTGATCGAGGAGCCGATGGCCGCCGCGATCGGCGCCGACATGCCGGTGACCGAACCCATC
GGGTCGATGGTCGTCGACATCGGCGGCGGCACCACCGAAGTCGCGGTGCTGTCGCTTCGCGGTCTCGCTTACACCACCTC
GGTCCGCGCCGGCGGCGACAAGATGGACGAGGCGATCGTCTCCTATGTCCGCCGCCACCATAATCTGCTGATCGGCGAAT
CGACCGCCGAACGGATCAAGAAGGATTTCGGCATCGCGCGCATCCCCGCCGACGGCGTGGGCCTGACGATCCACATCAAG
GGCCGCGACCTCGTCAACGGGGTGCCCAAGGAAATCTCGATCAACCAGGCGCAGATCGCCGAGGCGCTGTCCGAACCGAT
CGGCACGATCGTCGAGGGCGTGCGCATCGCGCTCGAAAACACCGCACCCGAACTCGCCGCCGACATCGTCGATCAGGGGA
TCGTGCTGACCGGCGGCGGCGCGCTGATCGCCGAACTCGACGAATTGTTGCGCGATGCGACCGGCCTGCCGGTGACGGTC
GCCGACGATCCGCTGACCTGCGTTGCGATCGGCACCGGTCGCGCGATGGAAGACCCCGCCTTCCGCGGCGTGCTCCAACA
AGCCTGA

Upstream 100 bases:

>100_bases
CCCCAGATTTGGTCCTGTTGTCGGACGGCAACGAGCAATTTATGACGACGGTGGGCGGCCCGTTCGGACGCCGCGCCGTC
GATGACAGGAACTATAGCTG

Downstream 100 bases:

>100_bases
TCGGGTAGCATCGCGTCGTGGTCCGCCCGGCACATCGACGTCCGGGGCAATCCCGAAAGGCCCAGTACAGCCTGTTCGTC
GCCTATGTCATCGCGGTGAC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSFFSRWFKFNSQDMAIDLGTANTVVYVRGKGIVLNEPSVVAVETLNGIKRVKAVGDDAKLMMGKTPDSIEAIRPLRDGV
IADIDVAEQMIKHFITKVHGGKPNAFRSPEIVICVPSGSTSVERRAIRDAASNAGASEVWLIEEPMAAAIGADMPVTEPI
GSMVVDIGGGTTEVAVLSLRGLAYTTSVRAGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDFGIARIPADGVGLTIHIK
GRDLVNGVPKEISINQAQIAEALSEPIGTIVEGVRIALENTAPELAADIVDQGIVLTGGGALIAELDELLRDATGLPVTV
ADDPLTCVAIGTGRAMEDPAFRGVLQQA

Sequences:

>Translated_348_residues
MSFFSRWFKFNSQDMAIDLGTANTVVYVRGKGIVLNEPSVVAVETLNGIKRVKAVGDDAKLMMGKTPDSIEAIRPLRDGV
IADIDVAEQMIKHFITKVHGGKPNAFRSPEIVICVPSGSTSVERRAIRDAASNAGASEVWLIEEPMAAAIGADMPVTEPI
GSMVVDIGGGTTEVAVLSLRGLAYTTSVRAGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDFGIARIPADGVGLTIHIK
GRDLVNGVPKEISINQAQIAEALSEPIGTIVEGVRIALENTAPELAADIVDQGIVLTGGGALIAELDELLRDATGLPVTV
ADDPLTCVAIGTGRAMEDPAFRGVLQQA
>Mature_347_residues
SFFSRWFKFNSQDMAIDLGTANTVVYVRGKGIVLNEPSVVAVETLNGIKRVKAVGDDAKLMMGKTPDSIEAIRPLRDGVI
ADIDVAEQMIKHFITKVHGGKPNAFRSPEIVICVPSGSTSVERRAIRDAASNAGASEVWLIEEPMAAAIGADMPVTEPIG
SMVVDIGGGTTEVAVLSLRGLAYTTSVRAGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDFGIARIPADGVGLTIHIKG
RDLVNGVPKEISINQAQIAEALSEPIGTIVEGVRIALENTAPELAADIVDQGIVLTGGGALIAELDELLRDATGLPVTVA
DDPLTCVAIGTGRAMEDPAFRGVLQQA

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=375, Percent_Identity=28.2666666666667, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082236, Length=339, Percent_Identity=58.1120943952802, Blast_Score=380, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17507981, Length=379, Percent_Identity=25.5936675461741, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36738; Mature: 36606

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFSRWFKFNSQDMAIDLGTANTVVYVRGKGIVLNEPSVVAVETLNGIKRVKAVGDDAK
CCHHHHHHHCCCCCEEEEECCCCEEEEEECCEEEECCCCEEEEHHHHHHHHHHHCCCCCE
LMMGKTPDSIEAIRPLRDGVIADIDVAEQMIKHFITKVHGGKPNAFRSPEIVICVPSGST
EEECCCCCHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCC
SVERRAIRDAASNAGASEVWLIEEPMAAAIGADMPVTEPIGSMVVDIGGGTTEVAVLSLR
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEEC
GLAYTTSVRAGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDFGIARIPADGVGLTIHIK
CCEEEEEECCCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCEEECCCCCCEEEEEEC
GRDLVNGVPKEISINQAQIAEALSEPIGTIVEGVRIALENTAPELAADIVDQGIVLTGGG
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCEEEECCC
ALIAELDELLRDATGLPVTVADDPLTCVAIGTGRAMEDPAFRGVLQQA
HHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SFFSRWFKFNSQDMAIDLGTANTVVYVRGKGIVLNEPSVVAVETLNGIKRVKAVGDDAK
CHHHHHHHCCCCCEEEEECCCCEEEEEECCEEEECCCCEEEEHHHHHHHHHHHCCCCCE
LMMGKTPDSIEAIRPLRDGVIADIDVAEQMIKHFITKVHGGKPNAFRSPEIVICVPSGST
EEECCCCCHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCC
SVERRAIRDAASNAGASEVWLIEEPMAAAIGADMPVTEPIGSMVVDIGGGTTEVAVLSLR
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEECCCCCCEEEEEEEC
GLAYTTSVRAGGDKMDEAIVSYVRRHHNLLIGESTAERIKKDFGIARIPADGVGLTIHIK
CCEEEEEECCCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCEEECCCCCCEEEEEEC
GRDLVNGVPKEISINQAQIAEALSEPIGTIVEGVRIALENTAPELAADIVDQGIVLTGGG
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCEEEECCC
ALIAELDELLRDATGLPVTVADDPLTCVAIGTGRAMEDPAFRGVLQQA
HHHHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]