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The map label for this gene is ahpC [H]

Identifier: 103486122

GI number: 103486122

Start: 639690

End: 640253

Strand: Direct

Name: ahpC [H]

Synonym: Sala_0629

Alternate gene names: 103486122

Gene position: 639690-640253 (Clockwise)

Preceding gene: 103486121

Following gene: 103486123

Centisome position: 19.12

GC content: 59.75

Gene sequence:

>564_bases
ATGGGTATCATCGGAAGTTCGATCAAGCCGTTCAGCGCCACCTCTTACCATCAGGGCAAGTTCGTCCCCGTGACGGACGC
CGATGTGAAGGGCAAATGGGCGGTGTTCTTCTTCTATCCGGCCGACTTCACCTTCGTCTGCCCGACCGAGCTCGAAGACC
TCGCCGACCAGTATGAAACGCTCCAGAGCCTTGGCGTCGAAGTCTATGCCGTTTCGACCGACACGCATTTCAGCCACAAG
GCTTGGCACGACAGTTCACCGGCGATCGGCAAGATCGCCTATCACATGCTGGGTGACCAGAACCATGTCCTCGCCAATAA
TTTCGGCGTGCTGCGCGAAGATTCGGGCCTTGCCGACCGCGCGACCTTCGTTGTCGATCCCGACGGAGTGATTCAGGTGA
TGGAAATCACCTGCGAAGGCGTCGGCCGCAATGCAGGGGAACTGGTCCGCAAGATCAAGGCTGCGATCCATGTCCGCGCC
AACCCCGGCCAGGTCTGCCCGGCGAAGTGGGAAGAGGGCGCCGAAACGCTCGCTCCCTCGATCGAACTCGTCGGCAAGAT
CTAA

Upstream 100 bases:

>100_bases
GGAAATTTGGGGTTGAGTGCTGCGGCCGCTCGGCATAGCTGGCCCCTGCAAATCATTTTGCAGTGCAGCAAACAGCAGCA
GATAAAGGAAACACTCTCCC

Downstream 100 bases:

>100_bases
GCCGGCGCAAGCCGGGACAAAATGGTGTGCCCCCGCGAAGGCGGGGGCCCATCTCCGGACGGAGCAAATCGCACCGGCAG
GTGATGGATCCCCGCTTTCG

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MGIIGSSIKPFSATSYHQGKFVPVTDADVKGKWAVFFFYPADFTFVCPTELEDLADQYETLQSLGVEVYAVSTDTHFSHK
AWHDSSPAIGKIAYHMLGDQNHVLANNFGVLREDSGLADRATFVVDPDGVIQVMEITCEGVGRNAGELVRKIKAAIHVRA
NPGQVCPAKWEEGAETLAPSIELVGKI

Sequences:

>Translated_187_residues
MGIIGSSIKPFSATSYHQGKFVPVTDADVKGKWAVFFFYPADFTFVCPTELEDLADQYETLQSLGVEVYAVSTDTHFSHK
AWHDSSPAIGKIAYHMLGDQNHVLANNFGVLREDSGLADRATFVVDPDGVIQVMEITCEGVGRNAGELVRKIKAAIHVRA
NPGQVCPAKWEEGAETLAPSIELVGKI
>Mature_186_residues
GIIGSSIKPFSATSYHQGKFVPVTDADVKGKWAVFFFYPADFTFVCPTELEDLADQYETLQSLGVEVYAVSTDTHFSHKA
WHDSSPAIGKIAYHMLGDQNHVLANNFGVLREDSGLADRATFVVDPDGVIQVMEITCEGVGRNAGELVRKIKAAIHVRAN
PGQVCPAKWEEGAETLAPSIELVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=180, Percent_Identity=41.1111111111111, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=40.4624277456647, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=37.3626373626374, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI4505591, Length=183, Percent_Identity=34.9726775956284, Blast_Score=130, Evalue=5e-31,
Organism=Homo sapiens, GI32455266, Length=183, Percent_Identity=34.9726775956284, Blast_Score=130, Evalue=5e-31,
Organism=Homo sapiens, GI32455264, Length=183, Percent_Identity=34.9726775956284, Blast_Score=130, Evalue=5e-31,
Organism=Homo sapiens, GI5453549, Length=172, Percent_Identity=37.2093023255814, Blast_Score=128, Evalue=3e-30,
Organism=Homo sapiens, GI33188454, Length=84, Percent_Identity=46.4285714285714, Blast_Score=84, Evalue=8e-17,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=63.6363636363636, Blast_Score=266, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=40.2234636871508, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32565831, Length=184, Percent_Identity=38.0434782608696, Blast_Score=138, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193204376, Length=184, Percent_Identity=38.0434782608696, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320661, Length=176, Percent_Identity=34.6590909090909, Blast_Score=116, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=37.1428571428571, Blast_Score=115, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319407, Length=158, Percent_Identity=28.4810126582279, Blast_Score=68, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21357347, Length=170, Percent_Identity=37.0588235294118, Blast_Score=133, Evalue=7e-32,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=35.0282485875706, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24656348, Length=183, Percent_Identity=33.879781420765, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17864676, Length=183, Percent_Identity=33.879781420765, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=33.5294117647059, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=33.5294117647059, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=32.2784810126582, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24652436, Length=163, Percent_Identity=28.2208588957055, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=27.8481012658228, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20339; Mature: 20208

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIIGSSIKPFSATSYHQGKFVPVTDADVKGKWAVFFFYPADFTFVCPTELEDLADQYET
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCEEEECCCHHHHHHHHHHH
LQSLGVEVYAVSTDTHFSHKAWHDSSPAIGKIAYHMLGDQNHVLANNFGVLREDSGLADR
HHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEEECCCCCCCC
ATFVVDPDGVIQVMEITCEGVGRNAGELVRKIKAAIHVRANPGQVCPAKWEEGAETLAPS
EEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHEEEECCCCCCCCCCHHCCHHHHCCC
IELVGKI
CEEEECC
>Mature Secondary Structure 
GIIGSSIKPFSATSYHQGKFVPVTDADVKGKWAVFFFYPADFTFVCPTELEDLADQYET
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCEEEECCCHHHHHHHHHHH
LQSLGVEVYAVSTDTHFSHKAWHDSSPAIGKIAYHMLGDQNHVLANNFGVLREDSGLADR
HHHCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCEEECCCCCCCC
ATFVVDPDGVIQVMEITCEGVGRNAGELVRKIKAAIHVRANPGQVCPAKWEEGAETLAPS
EEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHEEEECCCCCCCCCCHHCCHHHHCCC
IELVGKI
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]