| Definition | Sphingopyxis alaskensis RB2256, complete genome. |
|---|---|
| Accession | NC_008048 |
| Length | 3,345,170 |
Click here to switch to the map view.
The map label for this gene is gno [H]
Identifier: 103485792
GI number: 103485792
Start: 295766
End: 296542
Strand: Direct
Name: gno [H]
Synonym: Sala_0297
Alternate gene names: 103485792
Gene position: 295766-296542 (Clockwise)
Preceding gene: 103485788
Following gene: 103485793
Centisome position: 8.84
GC content: 68.34
Gene sequence:
>777_bases ATGGCCGAGCAACCGAAGTTCGATCTGACGGGGCGTGTGGCGCTGGTTACGGGGGCGTCGTCGGGGCTGGGCGCGGGGTT TGCCAAGGCGCTGGCCGCGGCGGGGGCCAAGGTCGTGCTCGCTGCGCGGCGCGCCGACAAGCTGGCGGAGCAGGTGGCGG CGATCGAGGCGGCGGGCGGGCAGGCGGTCGCGGTGAGCATGGATGTCACCGACGAAGCATCGACCAAGGCGGCCTATGAC GCCGCCGAAGCCGCCTTTGGCACCGTCGACACGATTGTCGCCAACGCCGGGGTCGCGACCGAGAAGATGGCGATGAGCCT GTCGGTCGAGGATGTCGATTTCCTGCTCGCCGCCAATGTGCGCGGCGTGTTCCTGACCGCAAACGAAGGCGCGAAACGGC TCGACCAGGCGGGGAGCCGCGAGAAGCAGCATGGGCGCATCGTGCTGATCGGGTCGATCACTGCGGAGAAGGTCTTTCCG GCCACCTCGGTCTATGGCGCGACCAAGGCGGCGGTGCGCCATCTGGGCAAGGCGCTGGCGCGCGAATGGGCGCGGCGCGG GATATGCGTCAATGTCATCCAGCCGGGCTATTTCGAATCCGAAATGACCGCCGAACTGCTCGAAAGCGACGCGGGGGCGG CGATGGTCAAAAGCTTTCCGCGCCAGCGGATGCGCCCCGCGACCGACCTGCACGCGCCGCTGCTGTTGCTTTGCTCCGAC GCCGCGGCGGGCGTCACGGGAAGCGTGTTCACGATCGACGACGGGCAGACTTTGTGA
Upstream 100 bases:
>100_bases GAGTCAACCCGGCCGTCCGCTTTTTCCGTCGATCACTCCGGGCGGTTGACGTAAACGTCAATCGGCGCCAGGGCCGGGCC AGCCAAGGAAAGGGAGACGC
Downstream 100 bases:
>100_bases GCGCGCTGCTGATCGAGGCGCGCGGTGCGGTCGAGATCGCGACGCTGAACCGGCCCGAACGGCTGAATGCGCTGAACGAG GAGCTGGTCGACGAACTCAA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 258; Mature: 257
Protein sequence:
>258_residues MAEQPKFDLTGRVALVTGASSGLGAGFAKALAAAGAKVVLAARRADKLAEQVAAIEAAGGQAVAVSMDVTDEASTKAAYD AAEAAFGTVDTIVANAGVATEKMAMSLSVEDVDFLLAANVRGVFLTANEGAKRLDQAGSREKQHGRIVLIGSITAEKVFP ATSVYGATKAAVRHLGKALAREWARRGICVNVIQPGYFESEMTAELLESDAGAAMVKSFPRQRMRPATDLHAPLLLLCSD AAAGVTGSVFTIDDGQTL
Sequences:
>Translated_258_residues MAEQPKFDLTGRVALVTGASSGLGAGFAKALAAAGAKVVLAARRADKLAEQVAAIEAAGGQAVAVSMDVTDEASTKAAYD AAEAAFGTVDTIVANAGVATEKMAMSLSVEDVDFLLAANVRGVFLTANEGAKRLDQAGSREKQHGRIVLIGSITAEKVFP ATSVYGATKAAVRHLGKALAREWARRGICVNVIQPGYFESEMTAELLESDAGAAMVKSFPRQRMRPATDLHAPLLLLCSD AAAGVTGSVFTIDDGQTL >Mature_257_residues AEQPKFDLTGRVALVTGASSGLGAGFAKALAAAGAKVVLAARRADKLAEQVAAIEAAGGQAVAVSMDVTDEASTKAAYDA AEAAFGTVDTIVANAGVATEKMAMSLSVEDVDFLLAANVRGVFLTANEGAKRLDQAGSREKQHGRIVLIGSITAEKVFPA TSVYGATKAAVRHLGKALAREWARRGICVNVIQPGYFESEMTAELLESDAGAAMVKSFPRQRMRPATDLHAPLLLLCSDA AAGVTGSVFTIDDGQTL
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=31.4516129032258, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=27.5193798449612, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI109715829, Length=205, Percent_Identity=31.219512195122, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI20149619, Length=211, Percent_Identity=32.7014218009479, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI7706318, Length=206, Percent_Identity=32.5242718446602, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI15277342, Length=216, Percent_Identity=31.4814814814815, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=27.3092369477912, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=29.4820717131474, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI4504505, Length=268, Percent_Identity=29.4776119402985, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=27.4590163934426, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI226371731, Length=198, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI209862901, Length=206, Percent_Identity=30.0970873786408, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI19923983, Length=206, Percent_Identity=30.0970873786408, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4758504, Length=233, Percent_Identity=30.9012875536481, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI7705855, Length=215, Percent_Identity=27.4418604651163, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=28.125, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4503301, Length=266, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI40254986, Length=127, Percent_Identity=33.0708661417323, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=34.5098039215686, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=34.2307692307692, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=31.4741035856574, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=30, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=30, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=32.5301204819277, Blast_Score=97, Evalue=2e-21, Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=30.5882352941176, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI2367365, Length=194, Percent_Identity=29.3814432989691, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=27.4193548387097, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=29.2307692307692, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=29.0196078431373, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=29.6153846153846, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1787526, Length=264, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=29.0836653386454, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=28.2868525896414, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17561272, Length=264, Percent_Identity=31.4393939393939, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=27.9352226720648, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=28.740157480315, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=28.125, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=30.1020408163265, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538182, Length=233, Percent_Identity=32.618025751073, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17568967, Length=204, Percent_Identity=30.8823529411765, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565030, Length=222, Percent_Identity=31.981981981982, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562906, Length=196, Percent_Identity=29.0816326530612, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI71982365, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17559104, Length=193, Percent_Identity=33.160621761658, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560220, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=24.9084249084249, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=27.3809523809524, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538486, Length=200, Percent_Identity=30, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560332, Length=199, Percent_Identity=31.1557788944724, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17562910, Length=202, Percent_Identity=26.7326732673267, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17531453, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562908, Length=196, Percent_Identity=28.0612244897959, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71997099, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=9e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=30.1980198019802, Blast_Score=71, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=28.8537549407115, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322226, Length=213, Percent_Identity=24.8826291079812, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=30.5882352941176, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI21357041, Length=265, Percent_Identity=31.3207547169811, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI116007236, Length=200, Percent_Identity=32, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=29.8387096774194, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI116007238, Length=178, Percent_Identity=33.1460674157303, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24641232, Length=219, Percent_Identity=30.5936073059361, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI24643142, Length=198, Percent_Identity=33.8383838383838, Blast_Score=87, Evalue=7e-18, Organism=Drosophila melanogaster, GI24644339, Length=263, Percent_Identity=27.7566539923954, Blast_Score=87, Evalue=2e-17, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=26.6932270916335, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI17737361, Length=232, Percent_Identity=34.051724137931, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI116007234, Length=203, Percent_Identity=32.512315270936, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI28574402, Length=205, Percent_Identity=31.219512195122, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24584744, Length=205, Percent_Identity=31.219512195122, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21358495, Length=211, Percent_Identity=27.9620853080569, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI161076933, Length=198, Percent_Identity=31.3131313131313, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24584748, Length=198, Percent_Identity=31.3131313131313, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21357673, Length=196, Percent_Identity=30.1020408163265, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI116007232, Length=181, Percent_Identity=33.1491712707182, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI24641388, Length=203, Percent_Identity=31.0344827586207, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI281364494, Length=207, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665247, Length=209, Percent_Identity=30.622009569378, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24663911, Length=208, Percent_Identity=25.9615384615385, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24665243, Length=209, Percent_Identity=30.622009569378, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI28571387, Length=217, Percent_Identity=25.3456221198157, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI18859837, Length=201, Percent_Identity=31.3432835820896, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24584752, Length=210, Percent_Identity=30, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24648944, Length=206, Percent_Identity=28.6407766990291, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331216, Length=202, Percent_Identity=30.6930693069307, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=30.6930693069307, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24640442, Length=201, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24648693, Length=218, Percent_Identity=28.4403669724771, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI21355889, Length=218, Percent_Identity=28.4403669724771, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 26582; Mature: 26450
Theoretical pI: Translated: 5.78; Mature: 5.78
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAEQPKFDLTGRVALVTGASSGLGAGFAKALAAAGAKVVLAARRADKLAEQVAAIEAAGG CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCC QAVAVSMDVTDEASTKAAYDAAEAAFGTVDTIVANAGVATEKMAMSLSVEDVDFLLAANV CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECHHHHHEEEECCC RGVFLTANEGAKRLDQAGSREKQHGRIVLIGSITAEKVFPATSVYGATKAAVRHLGKALA CEEEEECCCCHHHHHHCCCCCCCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHH REWARRGICVNVIQPGYFESEMTAELLESDAGAAMVKSFPRQRMRPATDLHAPLLLLCSD HHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCHHEEECC AAAGVTGSVFTIDDGQTL CCCCCCCEEEEECCCCCC >Mature Secondary Structure AEQPKFDLTGRVALVTGASSGLGAGFAKALAAAGAKVVLAARRADKLAEQVAAIEAAGG CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCC QAVAVSMDVTDEASTKAAYDAAEAAFGTVDTIVANAGVATEKMAMSLSVEDVDFLLAANV CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEECHHHHHEEEECCC RGVFLTANEGAKRLDQAGSREKQHGRIVLIGSITAEKVFPATSVYGATKAAVRHLGKALA CEEEEECCCCHHHHHHCCCCCCCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHH REWARRGICVNVIQPGYFESEMTAELLESDAGAAMVKSFPRQRMRPATDLHAPLLLLCSD HHHHHCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCHHEEECC AAAGVTGSVFTIDDGQTL CCCCCCCEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]