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The map label for this gene is nhaA1 [H]

Identifier: 99080704

GI number: 99080704

Start: 917168

End: 917932

Strand: Reverse

Name: nhaA1 [H]

Synonym: TM1040_0863

Alternate gene names: 99080704

Gene position: 917932-917168 (Counterclockwise)

Preceding gene: 99080705

Following gene: 99080700

Centisome position: 28.68

GC content: 60.78

Gene sequence:

>765_bases
ATGATTGCCCCGACACGCATGGCCCTGATCGCGGCCTGCGCGCTCTCTCTCTCTGCTCCGGCAGCGCGGGCGCTTGACCT
CAACGACATGTCCGACAGCGAAAAGGCCGCCTTTGGCGATGCCGTGCGCAGCTATCTCCTGGAGAACCCGCAGGTGATCC
TGGAGGCGGTGGACGTCCTCGAACAACAGCAGCAACAGGCCGAGGCCGCGCGCGATGACGCGCTGGTGGGCGCCAACCTG
CAGGAAATCCAGAACGATGGCTATTCCTGGGTGGGCGGCAACCCCGAAGGCGATGTGACGCTGGTTGAATTCATGGATTA
CCGCTGTGGCTATTGCCGCAAGGCGGTGCCCGAAATCGAGGCTCTTTTGGCGGCGGATAAGAATATTCGTTTTGTCATCA
AAGAGTTCCCAATCCTCGGCGAGGCGTCTGTGCTCTCATCCCGGTTTGCGATTGCCACCAAACTTGTGGCTGGTGATGAC
GCTTACAAGAGCGTGCATGACACGCTGATCGCGTTTCAGGGCGAGCCCAATGAGGTGGCGTTGCGTCGTATGGCGGAGGG
GCTGTCGCTTGACGCGGATGCAATCCTCGCCAAGATGAACGACGCAAAAGTGACAGAGCAGATCCAGCGCACGCGCAGCC
TGGCGCAGACGCTGTCCATTTCTGGCACGCCCACCTTTGTTCTGGAAGACGAGATGCTGCGCGGCTACCTGCCCGCAGAT
CAGTTGCAGATCATGGTGGAGGACATACGCGCCGGGCGCAGCTGA

Upstream 100 bases:

>100_bases
CCAAACGCGCAACCGGCCTTCTGGCCAAAGGGTCCCCGGCCTGGCGCCGGGCCCAGGATGTTCTAATTGCCTTTGAACAA
GACGAGAAAAGGAACCAAAA

Downstream 100 bases:

>100_bases
GCGCCCGTACCGGGGGCGCTGCCCCCGGCCCCTTCGGGGCCTCCCCCGGGATATTTCCAAGAAGATGAAGGCGGGGTTAT
TCCGCCGCTTTCATGTCCTC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MIAPTRMALIAACALSLSAPAARALDLNDMSDSEKAAFGDAVRSYLLENPQVILEAVDVLEQQQQQAEAARDDALVGANL
QEIQNDGYSWVGGNPEGDVTLVEFMDYRCGYCRKAVPEIEALLAADKNIRFVIKEFPILGEASVLSSRFAIATKLVAGDD
AYKSVHDTLIAFQGEPNEVALRRMAEGLSLDADAILAKMNDAKVTEQIQRTRSLAQTLSISGTPTFVLEDEMLRGYLPAD
QLQIMVEDIRAGRS

Sequences:

>Translated_254_residues
MIAPTRMALIAACALSLSAPAARALDLNDMSDSEKAAFGDAVRSYLLENPQVILEAVDVLEQQQQQAEAARDDALVGANL
QEIQNDGYSWVGGNPEGDVTLVEFMDYRCGYCRKAVPEIEALLAADKNIRFVIKEFPILGEASVLSSRFAIATKLVAGDD
AYKSVHDTLIAFQGEPNEVALRRMAEGLSLDADAILAKMNDAKVTEQIQRTRSLAQTLSISGTPTFVLEDEMLRGYLPAD
QLQIMVEDIRAGRS
>Mature_254_residues
MIAPTRMALIAACALSLSAPAARALDLNDMSDSEKAAFGDAVRSYLLENPQVILEAVDVLEQQQQQAEAARDDALVGANL
QEIQNDGYSWVGGNPEGDVTLVEFMDYRCGYCRKAVPEIEALLAADKNIRFVIKEFPILGEASVLSSRFAIATKLVAGDD
AYKSVHDTLIAFQGEPNEVALRRMAEGLSLDADAILAKMNDAKVTEQIQRTRSLAQTLSISGTPTFVLEDEMLRGYLPAD
QLQIMVEDIRAGRS

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 27610; Mature: 27610

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPTRMALIAACALSLSAPAARALDLNDMSDSEKAAFGDAVRSYLLENPQVILEAVDVL
CCCCHHHHHHHHHHHHHCCCCHHEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
EQQQQQAEAARDDALVGANLQEIQNDGYSWVGGNPEGDVTLVEFMDYRCGYCRKAVPEIE
HHHHHHHHHHHCCCCCCCCHHHHHCCCCEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
ALLAADKNIRFVIKEFPILGEASVLSSRFAIATKLVAGDDAYKSVHDTLIAFQGEPNEVA
HHHHCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCHHHH
LRRMAEGLSLDADAILAKMNDAKVTEQIQRTRSLAQTLSISGTPTFVLEDEMLRGYLPAD
HHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHCCCCHH
QLQIMVEDIRAGRS
HHHHHHHHHHCCCC
>Mature Secondary Structure
MIAPTRMALIAACALSLSAPAARALDLNDMSDSEKAAFGDAVRSYLLENPQVILEAVDVL
CCCCHHHHHHHHHHHHHCCCCHHEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
EQQQQQAEAARDDALVGANLQEIQNDGYSWVGGNPEGDVTLVEFMDYRCGYCRKAVPEIE
HHHHHHHHHHHCCCCCCCCHHHHHCCCCEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
ALLAADKNIRFVIKEFPILGEASVLSSRFAIATKLVAGDDAYKSVHDTLIAFQGEPNEVA
HHHHCCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCHHHH
LRRMAEGLSLDADAILAKMNDAKVTEQIQRTRSLAQTLSISGTPTFVLEDEMLRGYLPAD
HHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHCCCCHH
QLQIMVEDIRAGRS
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA