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The map label for this gene is waaA [H]

Identifier: 99080564

GI number: 99080564

Start: 780104

End: 781408

Strand: Reverse

Name: waaA [H]

Synonym: TM1040_0723

Alternate gene names: 99080564

Gene position: 781408-780104 (Counterclockwise)

Preceding gene: 99080565

Following gene: 99080563

Centisome position: 24.41

GC content: 63.52

Gene sequence:

>1305_bases
ATGACCGATCCATCGCAGGTCGCCCCGACCCTGCTCTATCACCTCTATCGCGGTGCCAGCACGCTCTTGGCGCCGCTGAT
GTGGTCCAAAGTTGCAGGCAAGCTGCGTGCGCATGGGCTTCCGGAAGAACGGGTTCGTGAACGCCTCGGGCACGCGACCC
TGCAGCGCCCCAAGGGCCGACTGATCTGGTTTCATGCCGCCTCTGTCGGCGAGAGCCTGTCGGTCCTCACGCTGATCAAA
CGTCTGGGCACCATGGCGCCGGATCTGGAATTCCTGATCACCTCGGGCACACCCACATCTGCCGATCTGGTCGCAAAACG
CCTGCCTCCCCGCACCCGCCACCAGTTTCCGCCTCTGGACACCAGAGCCGCGGTGACGCGATTTCTGAACCATTGGCAGC
CGGACCTCGGGGTCTTTGTCGAAAGCGAGCTTTGGCCGCAAATGCTGGTGCGCGCGCGCGATGCGGGCGTCCCATTGGTG
CTGCTCAATGCGCGTCTTTCGCCCAAATCGGTCGCCAGCTGGAAGAAACGGCACGCCACCGCGCGGTTTCTACTGGATCA
GCTTGCGCTGATGCTCACCCAGAACAGCCAGACGGCGATCAACCTCAAGGCCATTGGTGCAGACCCCACACGTTTGCGCG
CTGGCAGCAACCTTAAGGCGCTCTCGGAGCCCCTGCCAGTGGATCAGGCCATCCTGGAGGACGTCCGGGACGCAATCGGT
GCGCGACCGGTCTGGGTCGCTTCCTCCACCCATGAGGGCGAGGAGGAAGTCGTGTTAGAGGCGCATAGAGCGCTCTTGGC
GGATCATCCGGATCTGCTGCTCTTGCTCGCGCCACGCCACCCACACCGGGGCGATCAAATCGAAGCGATGATTGCCGAGG
CAGGCCTCACTTCCATTCGGCGCAGTCGGGACGCCCTGCCCCGCACCTCGACACAGGTGTATCTTGCGGACACATTGGGC
GAAGTGGGCATCTGGTACAGCCTGTGCCCACGGGTCTTCCTTGGCGGTTCTCTCCGCGAAATCGGAGGGCACAACCCCTT
TGAGGTGATGCAAGCGGGAGGCGCGGTGCTGACTGGGTCCGGGGCCTATAATTTTGCCGAATCCTTTGCGGAGCTGATCG
AGCTAGGCGCGGCCCATGAAGTTCAGGATGCCAGCTCGCTTGCCGACGCGGTCAGGACTTGGCTCGACGCGCCGCATACC
CTAGACACGGCCCGCGCGCGGGCACGCGATTTTCTGGCCCGCCAATCCGACCAGATGGATGACACTGTGACGGCGCTGCT
CGACTTGCTGCCGTCCCCCACATAA

Upstream 100 bases:

>100_bases
ACCTCAAGCCCAAAGGGCATGATTTTGACTACTCCCGCCAGACCGTCGACGGCCAGATGCCGCGCCACATGAGCCACACC
GGCGGGTAAGGCTCCAGACG

Downstream 100 bases:

>100_bases
AGGGCGCCTGATGAGCCAGATCGACCTCAACCAGATCGACGTGATCGCGCCGAACTTTAAGAAACGCTATTCTGGTGTGA
CTTCTACCGTGATCCGGCTC

Product: three-deoxy-D-manno-octulosonic-acid transferase-like

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTDPSQVAPTLLYHLYRGASTLLAPLMWSKVAGKLRAHGLPEERVRERLGHATLQRPKGRLIWFHAASVGESLSVLTLIK
RLGTMAPDLEFLITSGTPTSADLVAKRLPPRTRHQFPPLDTRAAVTRFLNHWQPDLGVFVESELWPQMLVRARDAGVPLV
LLNARLSPKSVASWKKRHATARFLLDQLALMLTQNSQTAINLKAIGADPTRLRAGSNLKALSEPLPVDQAILEDVRDAIG
ARPVWVASSTHEGEEEVVLEAHRALLADHPDLLLLLAPRHPHRGDQIEAMIAEAGLTSIRRSRDALPRTSTQVYLADTLG
EVGIWYSLCPRVFLGGSLREIGGHNPFEVMQAGGAVLTGSGAYNFAESFAELIELGAAHEVQDASSLADAVRTWLDAPHT
LDTARARARDFLARQSDQMDDTVTALLDLLPSPT

Sequences:

>Translated_434_residues
MTDPSQVAPTLLYHLYRGASTLLAPLMWSKVAGKLRAHGLPEERVRERLGHATLQRPKGRLIWFHAASVGESLSVLTLIK
RLGTMAPDLEFLITSGTPTSADLVAKRLPPRTRHQFPPLDTRAAVTRFLNHWQPDLGVFVESELWPQMLVRARDAGVPLV
LLNARLSPKSVASWKKRHATARFLLDQLALMLTQNSQTAINLKAIGADPTRLRAGSNLKALSEPLPVDQAILEDVRDAIG
ARPVWVASSTHEGEEEVVLEAHRALLADHPDLLLLLAPRHPHRGDQIEAMIAEAGLTSIRRSRDALPRTSTQVYLADTLG
EVGIWYSLCPRVFLGGSLREIGGHNPFEVMQAGGAVLTGSGAYNFAESFAELIELGAAHEVQDASSLADAVRTWLDAPHT
LDTARARARDFLARQSDQMDDTVTALLDLLPSPT
>Mature_433_residues
TDPSQVAPTLLYHLYRGASTLLAPLMWSKVAGKLRAHGLPEERVRERLGHATLQRPKGRLIWFHAASVGESLSVLTLIKR
LGTMAPDLEFLITSGTPTSADLVAKRLPPRTRHQFPPLDTRAAVTRFLNHWQPDLGVFVESELWPQMLVRARDAGVPLVL
LNARLSPKSVASWKKRHATARFLLDQLALMLTQNSQTAINLKAIGADPTRLRAGSNLKALSEPLPVDQAILEDVRDAIGA
RPVWVASSTHEGEEEVVLEAHRALLADHPDLLLLLAPRHPHRGDQIEAMIAEAGLTSIRRSRDALPRTSTQVYLADTLGE
VGIWYSLCPRVFLGGSLREIGGHNPFEVMQAGGAVLTGSGAYNFAESFAELIELGAAHEVQDASSLADAVRTWLDAPHTL
DTARARARDFLARQSDQMDDTVTALLDLLPSPT

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=385, Percent_Identity=36.8831168831169, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 47495; Mature: 47364

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPSQVAPTLLYHLYRGASTLLAPLMWSKVAGKLRAHGLPEERVRERLGHATLQRPKGR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
LIWFHAASVGESLSVLTLIKRLGTMAPDLEFLITSGTPTSADLVAKRLPPRTRHQFPPLD
EEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
TRAAVTRFLNHWQPDLGVFVESELWPQMLVRARDAGVPLVLLNARLSPKSVASWKKRHAT
HHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
ARFLLDQLALMLTQNSQTAINLKAIGADPTRLRAGSNLKALSEPLPVDQAILEDVRDAIG
HHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHC
ARPVWVASSTHEGEEEVVLEAHRALLADHPDLLLLLAPRHPHRGDQIEAMIAEAGLTSIR
CCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RSRDALPRTSTQVYLADTLGEVGIWYSLCPRVFLGGSLREIGGHNPFEVMQAGGAVLTGS
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHCCCCEEECC
GAYNFAESFAELIELGAAHEVQDASSLADAVRTWLDAPHTLDTARARARDFLARQSDQMD
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHH
DTVTALLDLLPSPT
HHHHHHHHHCCCCC
>Mature Secondary Structure 
TDPSQVAPTLLYHLYRGASTLLAPLMWSKVAGKLRAHGLPEERVRERLGHATLQRPKGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
LIWFHAASVGESLSVLTLIKRLGTMAPDLEFLITSGTPTSADLVAKRLPPRTRHQFPPLD
EEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
TRAAVTRFLNHWQPDLGVFVESELWPQMLVRARDAGVPLVLLNARLSPKSVASWKKRHAT
HHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
ARFLLDQLALMLTQNSQTAINLKAIGADPTRLRAGSNLKALSEPLPVDQAILEDVRDAIG
HHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHC
ARPVWVASSTHEGEEEVVLEAHRALLADHPDLLLLLAPRHPHRGDQIEAMIAEAGLTSIR
CCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RSRDALPRTSTQVYLADTLGEVGIWYSLCPRVFLGGSLREIGGHNPFEVMQAGGAVLTGS
HHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHCCCCEEECC
GAYNFAESFAELIELGAAHEVQDASSLADAVRTWLDAPHTLDTARARARDFLARQSDQMD
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHH
DTVTALLDLLPSPT
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]