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The map label for this gene is gfo [H]

Identifier: 94985576

GI number: 94985576

Start: 1562325

End: 1563437

Strand: Reverse

Name: gfo [H]

Synonym: Dgeo_1476

Alternate gene names: 94985576

Gene position: 1563437-1562325 (Counterclockwise)

Preceding gene: 94985579

Following gene: 94985571

Centisome position: 63.37

GC content: 63.88

Gene sequence:

>1113_bases
ATGCCGCAAAAGCCAGAAATTCCCTTGCCCGAATCCGAGTCACGCCGTGTGGGGTACGCCATTGTCGGCATCGGCGAACT
GAGCAGTGAGGAACTGATTCCCGCCGCGCGCACGAGTGAGCATGCCTACGTGGCCGCCCTGGTGACGGGTGATCCTGAGA
AGGGCAAGGCGTTTGCGCACGCTTACGACCTGACCGAAGGAGACGTATACACCTACGAGCGCTTTGAGGCCCTGAAAGAC
CGCGAGGATGTGGAAGCGGTCTACATCGTTCTTCCCAACAGCCTGCACCGCGAGTACACGGAGCGAGCGGCCAAAATGGG
CAAGCACGTCCTGTGCGAAAAGCCGCTCAGCGTGAATGCCGCAGACGCGCAAGCGATGGTGGATGCCTGCCGGGCGGCGG
GCGTGCTGCTGATGACGGCCTACCGCTGTCAGTACACGCCTCAACACTGGGCGGCTCGGGAGGCCGTGCAGGGAGGCAAG
ATCGGTCCGGTCAAGCTGCTGGACGCCATTCATGGCCAGGTAGAGCAAGATCCTGAAGCGTGGCGGCTGAAGCGTGATCT
GGCGGGCGGTGGGCCTCTGCCCGACGTCGGCATCTACTGCCTGAACACCATTCGGTTCATGCTGGGCCAAGAACCCGAGT
GGGTCTTGGCCACCCTGCATCAGCCACAGGACGACCCGCGCTTTCGGGAAGTCGAGGAATCCATGAGCTTCCTGCTGGGC
TTTCCCGGCGGCGTCGTCGCCAATTGCCTCACCAGCTACGGCACACAAAAAACCGCGACCCTGCGCGTCTTGGGAGAACA
GGGCACCGTGCTGATGGATCCCGCCTACACCTATCAGGGGCTGCGCCTCACCCTCTCGGACCAACACGGTGACGTCCAGC
CGCGGCTTCCCGATGAGGACCAGTTCGGGTTGGAGTTCGATCACTTCGCCCAGTGTATTCGCGCGGGCAAAACGCCCTGG
ACGCCCGGTGAGGAGGGCGTGCAGGATCACCGCATCATGGACGCGCTGTACCAAAGCGCCCGCAGCGGCCAGGTGGTGCG
CCTCGAGCGGATGGAAGGGCGGGACGTTTTCCGCGGCGAAAAGCCGCAGGTGCCGAGCGGGGGGTCCCAGTAG

Upstream 100 bases:

>100_bases
GCAAGCTTTTCTGAAACGCAGAGCAGCGGGCCGGTCTCGCCTGAAGAAGTGCTCAAGCTCCGCCACAAACAGGCTTGTTT
GCCGCTTGTTACGGTGCGGT

Downstream 100 bases:

>100_bases
GTCAGCCCCAGGAGCCGGCCCCGGGGCCAGCTCCTGGCCCCGGGGCGCAAGCGCAGCTTTCTCCGGCTGGAGGCCTAGGC
CAGGAAGCCGGCCGAGCGGT

Product: oxidoreductase-like protein

Products: NA

Alternate protein names: GFOR [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MPQKPEIPLPESESRRVGYAIVGIGELSSEELIPAARTSEHAYVAALVTGDPEKGKAFAHAYDLTEGDVYTYERFEALKD
REDVEAVYIVLPNSLHREYTERAAKMGKHVLCEKPLSVNAADAQAMVDACRAAGVLLMTAYRCQYTPQHWAAREAVQGGK
IGPVKLLDAIHGQVEQDPEAWRLKRDLAGGGPLPDVGIYCLNTIRFMLGQEPEWVLATLHQPQDDPRFREVEESMSFLLG
FPGGVVANCLTSYGTQKTATLRVLGEQGTVLMDPAYTYQGLRLTLSDQHGDVQPRLPDEDQFGLEFDHFAQCIRAGKTPW
TPGEEGVQDHRIMDALYQSARSGQVVRLERMEGRDVFRGEKPQVPSGGSQ

Sequences:

>Translated_370_residues
MPQKPEIPLPESESRRVGYAIVGIGELSSEELIPAARTSEHAYVAALVTGDPEKGKAFAHAYDLTEGDVYTYERFEALKD
REDVEAVYIVLPNSLHREYTERAAKMGKHVLCEKPLSVNAADAQAMVDACRAAGVLLMTAYRCQYTPQHWAAREAVQGGK
IGPVKLLDAIHGQVEQDPEAWRLKRDLAGGGPLPDVGIYCLNTIRFMLGQEPEWVLATLHQPQDDPRFREVEESMSFLLG
FPGGVVANCLTSYGTQKTATLRVLGEQGTVLMDPAYTYQGLRLTLSDQHGDVQPRLPDEDQFGLEFDHFAQCIRAGKTPW
TPGEEGVQDHRIMDALYQSARSGQVVRLERMEGRDVFRGEKPQVPSGGSQ
>Mature_369_residues
PQKPEIPLPESESRRVGYAIVGIGELSSEELIPAARTSEHAYVAALVTGDPEKGKAFAHAYDLTEGDVYTYERFEALKDR
EDVEAVYIVLPNSLHREYTERAAKMGKHVLCEKPLSVNAADAQAMVDACRAAGVLLMTAYRCQYTPQHWAAREAVQGGKI
GPVKLLDAIHGQVEQDPEAWRLKRDLAGGGPLPDVGIYCLNTIRFMLGQEPEWVLATLHQPQDDPRFREVEESMSFLLGF
PGGVVANCLTSYGTQKTATLRVLGEQGTVLMDPAYTYQGLRLTLSDQHGDVQPRLPDEDQFGLEFDHFAQCIRAGKTPWT
PGEEGVQDHRIMDALYQSARSGQVVRLERMEGRDVFRGEKPQVPSGGSQ

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=321, Percent_Identity=28.6604361370716, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI87082405, Length=290, Percent_Identity=25.8620689655172, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787574, Length=352, Percent_Identity=23.8636363636364, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI145693182, Length=213, Percent_Identity=26.2910798122066, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24581117, Length=261, Percent_Identity=24.904214559387, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24581115, Length=173, Percent_Identity=28.3236994219653, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008354
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.99.28 [H]

Molecular weight: Translated: 40953; Mature: 40822

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKPEIPLPESESRRVGYAIVGIGELSSEELIPAARTSEHAYVAALVTGDPEKGKAFAH
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEE
AYDLTEGDVYTYERFEALKDREDVEAVYIVLPNSLHREYTERAAKMGKHVLCEKPLSVNA
EEECCCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCC
ADAQAMVDACRAAGVLLMTAYRCQYTPQHWAAREAVQGGKIGPVKLLDAIHGQVEQDPEA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHH
WRLKRDLAGGGPLPDVGIYCLNTIRFMLGQEPEWVLATLHQPQDDPRFREVEESMSFLLG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHC
FPGGVVANCLTSYGTQKTATLRVLGEQGTVLMDPAYTYQGLRLTLSDQHGDVQPRLPDED
CCHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCC
QFGLEFDHFAQCIRAGKTPWTPGEEGVQDHRIMDALYQSARSGQVVRLERMEGRDVFRGE
CCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
KPQVPSGGSQ
CCCCCCCCCC
>Mature Secondary Structure 
PQKPEIPLPESESRRVGYAIVGIGELSSEELIPAARTSEHAYVAALVTGDPEKGKAFAH
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEE
AYDLTEGDVYTYERFEALKDREDVEAVYIVLPNSLHREYTERAAKMGKHVLCEKPLSVNA
EEECCCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCC
ADAQAMVDACRAAGVLLMTAYRCQYTPQHWAAREAVQGGKIGPVKLLDAIHGQVEQDPEA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHH
WRLKRDLAGGGPLPDVGIYCLNTIRFMLGQEPEWVLATLHQPQDDPRFREVEESMSFLLG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHC
FPGGVVANCLTSYGTQKTATLRVLGEQGTVLMDPAYTYQGLRLTLSDQHGDVQPRLPDED
CCHHHHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCEEEEEECCCCCCCCCCCCCC
QFGLEFDHFAQCIRAGKTPWTPGEEGVQDHRIMDALYQSARSGQVVRLERMEGRDVFRGE
CCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
KPQVPSGGSQ
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537789; 8472911; 8994968 [H]