Click here to switch to the map view.

The map label for this gene is prc [C]

Identifier: 94985579

GI number: 94985579

Start: 1564771

End: 1566120

Strand: Reverse

Name: prc [C]

Synonym: Dgeo_1479

Alternate gene names: 94985579

Gene position: 1566120-1564771 (Counterclockwise)

Preceding gene: 94985588

Following gene: 94985576

Centisome position: 63.48

GC content: 63.11

Gene sequence:

>1350_bases
ATGCCCTTCACCCGCTCGCCCTATCTTGGGCACGTGAACCGCAAACGGATGCTTCTCGTGGCTGGCGCCCTGGCTGCCAC
CGCCGCCGTCGGGTACGCGCAGATGAGCGCCTACTCGACAGCCGACCTGCTGAAAAGTGCTGAGGGCCGCACCTTCCTGC
AGGTTCTCGACGGCCTCAACCGCTACTACCTCTATCCGGTTGATCAGAAGAAGCTCCTCCAGGGGGCGATCAACGGGGCC
ATCGGCAGCCTGAACGACGAATTCACCTACTACAGCGATCCCGAGGACAACGCAATTCAGACCCAAGATCTCAAGGGCGA
GTTCTACGGAATCGGCGTGACGCTGGTCGCCGCCAACCCCGACGGCACCGGGAGCAAGGTGGACAACGTGTACAAGGGCG
GAGCCGCCGCCGCTGCGGGCGTACAGATTGGGGACGTGTTTGTGAAGGTGGATGACAAGGACGTGCTGCACAGCACCACT
GCCGAGGTTCAGCGCCTGGTGCGCGGGCAGAAGGGCACCAGCGTGACCATCACCTTTGCCCGCAACGGCAAGCCCTACAC
CGTGAAGATGGAGCGGCAGCCCGTCACCATCGTGAGTGTCGAGCAGACCATGCTGCCGGGCAATATCGGCTATATCGCGC
TGAACACCTTCAACAGCGAAAAGGTGAGCGCTCAGTTCCACGCGGCCATCGCCGATATGAAGAAGCGGAATGTGCAGAAG
CTGATCCTCGATCTGCGCGACAATGGCGGCGGCCTGCTGTACGCGGGCGTGGACGCGGCGGATCAGTTCCTGGGGAGCGG
CCCCATCGTCAGCCTGCGTGACCGCAATGGCAAGACCGAGGTGGTGGGGACGGCCACCAGTCAGCCCACCGACTACAGCG
GCAAGCTGGTTGTGCTGGTGAACAAGAATAGCGCCAGCGCCAGCGAGATCGTTGCTGGAGCGTTGCAGGACGACGCGCGG
GCCACCATCGTTGGGGAGCAGACCTTTGGTAAGGGCGTCGCGCAGGAGGTTTTCAATACGGCGGACGGAGGCCGGGTCGC
CATCGTGGCCGATGAATGGCTGACACCCAAGGGTCGCCAGATCCACAAGAAGGGCATTACGCCCGATGTGGTGGTGAAGG
ACACCCGCTACACCGTCCCGCTGAACTTCAGCGGCGCAGGTGCCGCCCCCAACACCAAGATCACGCTGATGGTGGAGGGC
AAGCCCGTGACCGTCACCGCGGACAAGGACGGCAAGTTCAGCTACACCGGCGAGGTGAAGCGTCCCCGGCGCAGCGCCGT
CCAGGGCGAGGCTGTGGTTGACCTCCAAGGCGACGCGATTCTGAAAAAGGCGCTGGATCTGCTAAAGTAA

Upstream 100 bases:

>100_bases
ATGCTCGCGGCCCAGCATAGCCTAGCCTTCCTCCTGAACGTGAAGGCGGCTTCATGGAGGGAGGCGCGGGCGCTGGGGGT
GTCCGTCACCTCTGCCTCAA

Downstream 100 bases:

>100_bases
GAAAGATTCAGCTGAACTGACCGGGCTTTGATCCCAGCTCAGTCCCAGTCCCACTCGCGCCAGTCGCTGGGTTTTGCCTC
GCGACGGGCGCTTTTTTCTG

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MPFTRSPYLGHVNRKRMLLVAGALAATAAVGYAQMSAYSTADLLKSAEGRTFLQVLDGLNRYYLYPVDQKKLLQGAINGA
IGSLNDEFTYYSDPEDNAIQTQDLKGEFYGIGVTLVAANPDGTGSKVDNVYKGGAAAAAGVQIGDVFVKVDDKDVLHSTT
AEVQRLVRGQKGTSVTITFARNGKPYTVKMERQPVTIVSVEQTMLPGNIGYIALNTFNSEKVSAQFHAAIADMKKRNVQK
LILDLRDNGGGLLYAGVDAADQFLGSGPIVSLRDRNGKTEVVGTATSQPTDYSGKLVVLVNKNSASASEIVAGALQDDAR
ATIVGEQTFGKGVAQEVFNTADGGRVAIVADEWLTPKGRQIHKKGITPDVVVKDTRYTVPLNFSGAGAAPNTKITLMVEG
KPVTVTADKDGKFSYTGEVKRPRRSAVQGEAVVDLQGDAILKKALDLLK

Sequences:

>Translated_449_residues
MPFTRSPYLGHVNRKRMLLVAGALAATAAVGYAQMSAYSTADLLKSAEGRTFLQVLDGLNRYYLYPVDQKKLLQGAINGA
IGSLNDEFTYYSDPEDNAIQTQDLKGEFYGIGVTLVAANPDGTGSKVDNVYKGGAAAAAGVQIGDVFVKVDDKDVLHSTT
AEVQRLVRGQKGTSVTITFARNGKPYTVKMERQPVTIVSVEQTMLPGNIGYIALNTFNSEKVSAQFHAAIADMKKRNVQK
LILDLRDNGGGLLYAGVDAADQFLGSGPIVSLRDRNGKTEVVGTATSQPTDYSGKLVVLVNKNSASASEIVAGALQDDAR
ATIVGEQTFGKGVAQEVFNTADGGRVAIVADEWLTPKGRQIHKKGITPDVVVKDTRYTVPLNFSGAGAAPNTKITLMVEG
KPVTVTADKDGKFSYTGEVKRPRRSAVQGEAVVDLQGDAILKKALDLLK
>Mature_448_residues
PFTRSPYLGHVNRKRMLLVAGALAATAAVGYAQMSAYSTADLLKSAEGRTFLQVLDGLNRYYLYPVDQKKLLQGAINGAI
GSLNDEFTYYSDPEDNAIQTQDLKGEFYGIGVTLVAANPDGTGSKVDNVYKGGAAAAAGVQIGDVFVKVDDKDVLHSTTA
EVQRLVRGQKGTSVTITFARNGKPYTVKMERQPVTIVSVEQTMLPGNIGYIALNTFNSEKVSAQFHAAIADMKKRNVQKL
ILDLRDNGGGLLYAGVDAADQFLGSGPIVSLRDRNGKTEVVGTATSQPTDYSGKLVVLVNKNSASASEIVAGALQDDARA
TIVGEQTFGKGVAQEVFNTADGGRVAIVADEWLTPKGRQIHKKGITPDVVVKDTRYTVPLNFSGAGAAPNTKITLMVEGK
PVTVTADKDGKFSYTGEVKRPRRSAVQGEAVVDLQGDAILKKALDLLK

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=362, Percent_Identity=29.0055248618785, Blast_Score=112, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 47823; Mature: 47692

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFTRSPYLGHVNRKRMLLVAGALAATAAVGYAQMSAYSTADLLKSAEGRTFLQVLDGLN
CCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
RYYLYPVDQKKLLQGAINGAIGSLNDEFTYYSDPEDNAIQTQDLKGEFYGIGVTLVAANP
CEEEEECCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEECCCCEEEEEEEEEEEECC
DGTGSKVDNVYKGGAAAAAGVQIGDVFVKVDDKDVLHSTTAEVQRLVRGQKGTSVTITFA
CCCCCHHHHHHCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
RNGKPYTVKMERQPVTIVSVEQTMLPGNIGYIALNTFNSEKVSAQFHAAIADMKKRNVQK
CCCCEEEEEECCCCEEEEEEEHEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCHHE
LILDLRDNGGGLLYAGVDAADQFLGSGPIVSLRDRNGKTEVVGTATSQPTDYSGKLVVLV
EEEEEECCCCEEEEEECCHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEEEE
NKNSASASEIVAGALQDDARATIVGEQTFGKGVAQEVFNTADGGRVAIVADEWLTPKGRQ
ECCCCCHHHHHHHHCCCCCEEEEEECHHHCCHHHHHHHHCCCCCEEEEEECCCCCCCCCH
IHKKGITPDVVVKDTRYTVPLNFSGAGAAPNTKITLMVEGKPVTVTADKDGKFSYTGEVK
HHHCCCCCCEEEECCEEEEEEECCCCCCCCCCEEEEEECCCEEEEEECCCCCEEECCCCC
RPRRSAVQGEAVVDLQGDAILKKALDLLK
CCHHHCCCCCEEEEECCHHHHHHHHHHHC
>Mature Secondary Structure 
PFTRSPYLGHVNRKRMLLVAGALAATAAVGYAQMSAYSTADLLKSAEGRTFLQVLDGLN
CCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
RYYLYPVDQKKLLQGAINGAIGSLNDEFTYYSDPEDNAIQTQDLKGEFYGIGVTLVAANP
CEEEEECCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEECCCCEEEEEEEEEEEECC
DGTGSKVDNVYKGGAAAAAGVQIGDVFVKVDDKDVLHSTTAEVQRLVRGQKGTSVTITFA
CCCCCHHHHHHCCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
RNGKPYTVKMERQPVTIVSVEQTMLPGNIGYIALNTFNSEKVSAQFHAAIADMKKRNVQK
CCCCEEEEEECCCCEEEEEEEHEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCHHE
LILDLRDNGGGLLYAGVDAADQFLGSGPIVSLRDRNGKTEVVGTATSQPTDYSGKLVVLV
EEEEEECCCCEEEEEECCHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEEEE
NKNSASASEIVAGALQDDARATIVGEQTFGKGVAQEVFNTADGGRVAIVADEWLTPKGRQ
ECCCCCHHHHHHHHCCCCCEEEEEECHHHCCHHHHHHHHCCCCCEEEEEECCCCCCCCCH
IHKKGITPDVVVKDTRYTVPLNFSGAGAAPNTKITLMVEGKPVTVTADKDGKFSYTGEVK
HHHCCCCCCEEEECCEEEEEEECCCCCCCCCCEEEEEECCCEEEEEECCCCCEEECCCCC
RPRRSAVQGEAVVDLQGDAILKKALDLLK
CCHHHCCCCCEEEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA