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The map label for this gene is glnS [H]

Identifier: 93005495

GI number: 93005495

Start: 787749

End: 789488

Strand: Direct

Name: glnS [H]

Synonym: Pcryo_0665

Alternate gene names: 93005495

Gene position: 787749-789488 (Clockwise)

Preceding gene: 93005492

Following gene: 93005496

Centisome position: 25.74

GC content: 44.43

Gene sequence:

>1740_bases
ATGAGTGAGCACTCAAGCAATAATGCACAAAAAGACGAACACAAAAACGACTTTATTCGTAATATTATTCGTGATGATGT
TAATGCGCAGAAATACCAACAGATTGTCACTCGTTTTCCACCTGAGCCAAATGGTTACTTGCACTTGGGACACGTAAAGT
CCATCTGCCTAAACTTTGGTGTGGCTGAGGAGTTTGGCGGCATCTGCAACCTGCGCTTTGATGACACCAACCCAACCGCA
GAAAAGCAAGACTTCATTGATAACATCGAGAATGATGTAAAATGGTTGGGCTTTGAGTGGGCAGGAGAGGCGTACCATGC
CTCAGGATATTTCGACCAACTTCATGCTTGGGCGATTCAGCTGATCAAGCAAGGCGATGCTTATGTAGATTTGCAATCGC
CTGAGCAAATTAAAGAAAATCGTGGCTCATTTAATGAAGCAGGCACAGCGTCACCACATCGTAATGCCAGTGTTGAAGAA
AATTTGCAACTCTTTGATGATATGAAAGAGGGCAAATATGCTGAAGGTAAAGCAGTGCTACGTGCCAAGATTGATATGGC
AAGCCCTAATATGAACCTACGTGATCCTGTTATCTATCGAATTATGCATCAAGCACATCACCAAACGGGGGATAAATGGT
GCATTTATCCGATGTATGACTTTGCTCACCCGTTATCTGATGCGCTTGAAGGCATTACCCATTCATTATGTACGTTAGAG
TTTGAAGACCATCGTCCATTTTATGACTGGGCAATAGAAAAAGTTGGCTTTGAGCAACCGCCGCATCAGTATGAGTTCTC
TCGTCTAAATGTCGACCATACATTGACCAGTAAGCGCAAATTAAAGCAGCTGGTTGATGAAAATATCGTTAGCGGTTGGG
ACGATCCACGTATGCCGACGATTGCTGGCATGCGTCGCCGTGGGTATACACCAGAAGGCTTACGTGATTTCTGTGAGCGT
GTTGGCGTGACCAAAGTAGACAGTGTTGTAGACTTTCGCTTATTAGAATTTAGTATTCGTCAGTCACTAGAGACGACAAC
TGGTCGTGGTATGGCGGTACTTAAGCCATTAAAAGTGACCATTACCAACTTTAGCGATGCTGTTAGCAGTTGGGATTTGC
AAAAGGCTGACACCGTTCAAGCACGTTTTGACGATGCCTCGCAGACTTTATGGCTAACTCAGCCCAATCATCCCAATGTC
GATATGGGTGAACGTGAAATTCCATTTACTGAGACCATTTATATTGACCAAGGCGATTATGAAATTGAGCCGCCAGCAGG
TTATAAGCGTTTATCACCAGAGAAAAATGAAATTCGTCTGCGTAATACCTATGTATTGGCCGTGACGGAGCATATTTTAG
ATGATAGCGGTAACGTGATTGAGCTTAAAGCAACGATTGATCCGGCGACTTTGGGCAATAATCCTGAAGGTCGTAAAGTT
AAAGGCGTGATTCATTGGGTATCGGCTAGCCAAGGCGTTTCAGCAACGGTGCGCATGTATGAGCAGCTATTTAGTGTCGA
AGACCCAAGTGGCGTCGCTGACGTCCATCAAGCCTTGAATCCTAACTCATTGACTGAGCTAAATGCTGTAGTTGAGCCAT
CATTGGTCAATGCAGACGCTGGCACGCGCTTCCAGTTTGAGCGTGAAGGTTACTTTATCTCTGATAGCGAAGATCATAGC
AGTGATAAGCCTGTCTTTAACCAAATCGTGAGCTTACGTGATAGTTATAAACCCGCTTAA

Upstream 100 bases:

>100_bases
GTTTTACGATATCGTTTTACTTTATCAAATATTTTGAATTTTACATGAGGCGTGATGGCACGTCGTATGAATTGACCATT
TGCGTTAGGAGCAATGCCCG

Downstream 100 bases:

>100_bases
TTTATCATTAGTGCAGTTCATATTTATTGTAAGAAAATACTGAACAATAGTGGTTTGCAATGTTGCCCATTTCTAGTACG
CTAGGGATGGGCTTTTTTGT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSEHSSNNAQKDEHKNDFIRNIIRDDVNAQKYQQIVTRFPPEPNGYLHLGHVKSICLNFGVAEEFGGICNLRFDDTNPTA
EKQDFIDNIENDVKWLGFEWAGEAYHASGYFDQLHAWAIQLIKQGDAYVDLQSPEQIKENRGSFNEAGTASPHRNASVEE
NLQLFDDMKEGKYAEGKAVLRAKIDMASPNMNLRDPVIYRIMHQAHHQTGDKWCIYPMYDFAHPLSDALEGITHSLCTLE
FEDHRPFYDWAIEKVGFEQPPHQYEFSRLNVDHTLTSKRKLKQLVDENIVSGWDDPRMPTIAGMRRRGYTPEGLRDFCER
VGVTKVDSVVDFRLLEFSIRQSLETTTGRGMAVLKPLKVTITNFSDAVSSWDLQKADTVQARFDDASQTLWLTQPNHPNV
DMGEREIPFTETIYIDQGDYEIEPPAGYKRLSPEKNEIRLRNTYVLAVTEHILDDSGNVIELKATIDPATLGNNPEGRKV
KGVIHWVSASQGVSATVRMYEQLFSVEDPSGVADVHQALNPNSLTELNAVVEPSLVNADAGTRFQFEREGYFISDSEDHS
SDKPVFNQIVSLRDSYKPA

Sequences:

>Translated_579_residues
MSEHSSNNAQKDEHKNDFIRNIIRDDVNAQKYQQIVTRFPPEPNGYLHLGHVKSICLNFGVAEEFGGICNLRFDDTNPTA
EKQDFIDNIENDVKWLGFEWAGEAYHASGYFDQLHAWAIQLIKQGDAYVDLQSPEQIKENRGSFNEAGTASPHRNASVEE
NLQLFDDMKEGKYAEGKAVLRAKIDMASPNMNLRDPVIYRIMHQAHHQTGDKWCIYPMYDFAHPLSDALEGITHSLCTLE
FEDHRPFYDWAIEKVGFEQPPHQYEFSRLNVDHTLTSKRKLKQLVDENIVSGWDDPRMPTIAGMRRRGYTPEGLRDFCER
VGVTKVDSVVDFRLLEFSIRQSLETTTGRGMAVLKPLKVTITNFSDAVSSWDLQKADTVQARFDDASQTLWLTQPNHPNV
DMGEREIPFTETIYIDQGDYEIEPPAGYKRLSPEKNEIRLRNTYVLAVTEHILDDSGNVIELKATIDPATLGNNPEGRKV
KGVIHWVSASQGVSATVRMYEQLFSVEDPSGVADVHQALNPNSLTELNAVVEPSLVNADAGTRFQFEREGYFISDSEDHS
SDKPVFNQIVSLRDSYKPA
>Mature_578_residues
SEHSSNNAQKDEHKNDFIRNIIRDDVNAQKYQQIVTRFPPEPNGYLHLGHVKSICLNFGVAEEFGGICNLRFDDTNPTAE
KQDFIDNIENDVKWLGFEWAGEAYHASGYFDQLHAWAIQLIKQGDAYVDLQSPEQIKENRGSFNEAGTASPHRNASVEEN
LQLFDDMKEGKYAEGKAVLRAKIDMASPNMNLRDPVIYRIMHQAHHQTGDKWCIYPMYDFAHPLSDALEGITHSLCTLEF
EDHRPFYDWAIEKVGFEQPPHQYEFSRLNVDHTLTSKRKLKQLVDENIVSGWDDPRMPTIAGMRRRGYTPEGLRDFCERV
GVTKVDSVVDFRLLEFSIRQSLETTTGRGMAVLKPLKVTITNFSDAVSSWDLQKADTVQARFDDASQTLWLTQPNHPNVD
MGEREIPFTETIYIDQGDYEIEPPAGYKRLSPEKNEIRLRNTYVLAVTEHILDDSGNVIELKATIDPATLGNNPEGRKVK
GVIHWVSASQGVSATVRMYEQLFSVEDPSGVADVHQALNPNSLTELNAVVEPSLVNADAGTRFQFEREGYFISDSEDHSS
DKPVFNQIVSLRDSYKPA

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=548, Percent_Identity=42.1532846715328, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI62241042, Length=529, Percent_Identity=33.4593572778828, Blast_Score=266, Evalue=5e-71,
Organism=Escherichia coli, GI1786895, Length=570, Percent_Identity=51.4035087719298, Blast_Score=611, Evalue=1e-176,
Organism=Escherichia coli, GI1788743, Length=108, Percent_Identity=32.4074074074074, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17543332, Length=550, Percent_Identity=39.0909090909091, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17511007, Length=531, Percent_Identity=30.8851224105461, Blast_Score=233, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6324742, Length=582, Percent_Identity=38.1443298969072, Blast_Score=357, Evalue=4e-99,
Organism=Saccharomyces cerevisiae, GI6321192, Length=562, Percent_Identity=33.4519572953737, Blast_Score=293, Evalue=6e-80,
Organism=Drosophila melanogaster, GI17864488, Length=547, Percent_Identity=40.9506398537477, Blast_Score=394, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24649466, Length=537, Percent_Identity=33.147113594041, Blast_Score=254, Evalue=9e-68,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65746; Mature: 65615

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHSSNNAQKDEHKNDFIRNIIRDDVNAQKYQQIVTRFPPEPNGYLHLGHVKSICLNFG
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCC
VAEEFGGICNLRFDDTNPTAEKQDFIDNIENDVKWLGFEWAGEAYHASGYFDQLHAWAIQ
CHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEEEECCCCEECCCHHHHHHHHHHH
LIKQGDAYVDLQSPEQIKENRGSFNEAGTASPHRNASVEENLQLFDDMKEGKYAEGKAVL
HHHCCCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
RAKIDMASPNMNLRDPVIYRIMHQAHHQTGDKWCIYPMYDFAHPLSDALEGITHSLCTLE
EEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEE
FEDHRPFYDWAIEKVGFEQPPHQYEFSRLNVDHTLTSKRKLKQLVDENIVSGWDDPRMPT
ECCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCH
IAGMRRRGYTPEGLRDFCERVGVTKVDSVVDFRLLEFSIRQSLETTTGRGMAVLKPLKVT
HHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEE
ITNFSDAVSSWDLQKADTVQARFDDASQTLWLTQPNHPNVDMGEREIPFTETIYIDQGDY
EECHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCE
EIEPPAGYKRLSPEKNEIRLRNTYVLAVTEHILDDSGNVIELKATIDPATLGNNPEGRKV
EECCCCCCCCCCCCCCCEEEEEEEEEEEEHHHHCCCCCEEEEEEECCHHHCCCCCCCCEE
KGVIHWVSASQGVSATVRMYEQLFSVEDPSGVADVHQALNPNSLTELNAVVEPSLVNADA
EEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCEECCCC
GTRFQFEREGYFISDSEDHSSDKPVFNQIVSLRDSYKPA
CCEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEHSSNNAQKDEHKNDFIRNIIRDDVNAQKYQQIVTRFPPEPNGYLHLGHVKSICLNFG
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHCC
VAEEFGGICNLRFDDTNPTAEKQDFIDNIENDVKWLGFEWAGEAYHASGYFDQLHAWAIQ
CHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHEEEEEEECCCCEECCCHHHHHHHHHHH
LIKQGDAYVDLQSPEQIKENRGSFNEAGTASPHRNASVEENLQLFDDMKEGKYAEGKAVL
HHHCCCCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
RAKIDMASPNMNLRDPVIYRIMHQAHHQTGDKWCIYPMYDFAHPLSDALEGITHSLCTLE
EEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEE
FEDHRPFYDWAIEKVGFEQPPHQYEFSRLNVDHTLTSKRKLKQLVDENIVSGWDDPRMPT
ECCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCH
IAGMRRRGYTPEGLRDFCERVGVTKVDSVVDFRLLEFSIRQSLETTTGRGMAVLKPLKVT
HHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEE
ITNFSDAVSSWDLQKADTVQARFDDASQTLWLTQPNHPNVDMGEREIPFTETIYIDQGDY
EECHHHHHHCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCE
EIEPPAGYKRLSPEKNEIRLRNTYVLAVTEHILDDSGNVIELKATIDPATLGNNPEGRKV
EECCCCCCCCCCCCCCCEEEEEEEEEEEEHHHHCCCCCEEEEEEECCHHHCCCCCCCCEE
KGVIHWVSASQGVSATVRMYEQLFSVEDPSGVADVHQALNPNSLTELNAVVEPSLVNADA
EEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCEECCCC
GTRFQFEREGYFISDSEDHSSDKPVFNQIVSLRDSYKPA
CCEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]