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The map label for this gene is visC [H]

Identifier: 93005423

GI number: 93005423

Start: 708077

End: 709354

Strand: Direct

Name: visC [H]

Synonym: Pcryo_0593

Alternate gene names: 93005423

Gene position: 708077-709354 (Clockwise)

Preceding gene: 93005422

Following gene: 93005424

Centisome position: 23.14

GC content: 46.87

Gene sequence:

>1278_bases
ATGAAAAATAACCATACGCTGATTATCGGCGGCGGTATCGTCGGTGCAACGCTTGCGCTCAAACTGGCACAAGACAATAA
GCCGGTGACACTCATTGATGCGCGCCCAAAGCGTAACGAGGAAGATTGGCAGCAAATACTGGGTCAACGTGATGCACGTG
TTTATGCGTTAAGTCTTGCCAGTATTGAATTATTAAAAGAAGTTGGCGCTTGGCAAAAAATAGCAGCGTCAGAGCGTAAA
GCTGATTACTTACAAATGCAGGTTTGGCAATTGAATGGTGTGGGCGAGCTGCTGTTCGGCGATAGTACTAATAATAGTGA
TGACAGTAATCAAAATTCTGAGCCGAAAATGCTTGGTAGTATGGTTGAGCCCGCAGTTATCGAATATGCATTATGGCAGC
GTTTATCTGCTACCGATTTAAAGCAATATCTAACGGTTATCGATGGGCAGAAGATCGTTGATATGGACTGGCTAGGTGCA
ACGCAAGGCTACCGCGTGACTTTGGATAACGATACCGTGATTGACGCGAATTTATTGGTTGGTGCTGACGGTCGCGGTTC
ATTCGTGCGCAAGCAAGCAGGTATTGAGCTTGATATTCTTGATTATAATCAAACCGCGATCTGTTGTGCGATTCAAACTG
AAAAGCCGCATCAAGCAACTGCTCGTCAAGCCATGCTGCCGACTGGTACGCTGGCATTATTGCCGCTCGCTGATATCACT
GATGAAGACAAAGCCAATCCACAGCATTGGCAGTCGATTGTATGGACATTACCACGTAATCAAGCATTGGCATTGATAGA
AGAACACCCGCGCTATATCGCTGATAAATTGGCTGCTGCCAGTCATTATGAGCTTGGTGCTATCTACAAAATTGAATCAA
TCGCCAGTTTTCCGCTAGCGGCGCAGCAAGCAAAGACTTATGTCTCGGATAATTTAGTATTGATTGGTGATGCGGCGCAT
GGGGTGCATCCACTTGCTGGGCAAGGGCTCAATCTTGGGATGCTCGATGTAAAAGCATTAAGCAAACAATTGGCGCATGA
TTATAACCGTAGTGGTGGGTCGCTTTGGGGCACCAATCAAACCTTGCGTAGCTATGAGCGCTTGCGTCGTCCGCATAACA
GTCTGATGATGCACAGCTTTTCGGCGCTTAACTGGCTGTTCGCTGGCTCGCTGGCTCAATTGCGTCCTATCCAACAACTT
CGTAATGAAGGTATGTATCGGGTTAGTAAAATCAAGCCATTGATGCGGCTATTTGCTAAGCAGGCGAGTGGGGTTTAG

Upstream 100 bases:

>100_bases
CTTAGTATTGATAAGCCATTAAAAAAATTCAAAAATCTAACTGCTGCTAATTATTAAAAATATCAGCGGATAACTCAAGT
AGCGAAACGAAGGATATTTT

Downstream 100 bases:

>100_bases
TGTTTAACGAACTTTCTAGATGAACTAAGGAAGGTATATGAAAAGTAAGTCATGGATGACGATAGGCGTTGTAATAGCTA
GCTTTATGTTAGCCTCCTGC

Product: UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKNNHTLIIGGGIVGATLALKLAQDNKPVTLIDARPKRNEEDWQQILGQRDARVYALSLASIELLKEVGAWQKIAASERK
ADYLQMQVWQLNGVGELLFGDSTNNSDDSNQNSEPKMLGSMVEPAVIEYALWQRLSATDLKQYLTVIDGQKIVDMDWLGA
TQGYRVTLDNDTVIDANLLVGADGRGSFVRKQAGIELDILDYNQTAICCAIQTEKPHQATARQAMLPTGTLALLPLADIT
DEDKANPQHWQSIVWTLPRNQALALIEEHPRYIADKLAAASHYELGAIYKIESIASFPLAAQQAKTYVSDNLVLIGDAAH
GVHPLAGQGLNLGMLDVKALSKQLAHDYNRSGGSLWGTNQTLRSYERLRRPHNSLMMHSFSALNWLFAGSLAQLRPIQQL
RNEGMYRVSKIKPLMRLFAKQASGV

Sequences:

>Translated_425_residues
MKNNHTLIIGGGIVGATLALKLAQDNKPVTLIDARPKRNEEDWQQILGQRDARVYALSLASIELLKEVGAWQKIAASERK
ADYLQMQVWQLNGVGELLFGDSTNNSDDSNQNSEPKMLGSMVEPAVIEYALWQRLSATDLKQYLTVIDGQKIVDMDWLGA
TQGYRVTLDNDTVIDANLLVGADGRGSFVRKQAGIELDILDYNQTAICCAIQTEKPHQATARQAMLPTGTLALLPLADIT
DEDKANPQHWQSIVWTLPRNQALALIEEHPRYIADKLAAASHYELGAIYKIESIASFPLAAQQAKTYVSDNLVLIGDAAH
GVHPLAGQGLNLGMLDVKALSKQLAHDYNRSGGSLWGTNQTLRSYERLRRPHNSLMMHSFSALNWLFAGSLAQLRPIQQL
RNEGMYRVSKIKPLMRLFAKQASGV
>Mature_425_residues
MKNNHTLIIGGGIVGATLALKLAQDNKPVTLIDARPKRNEEDWQQILGQRDARVYALSLASIELLKEVGAWQKIAASERK
ADYLQMQVWQLNGVGELLFGDSTNNSDDSNQNSEPKMLGSMVEPAVIEYALWQRLSATDLKQYLTVIDGQKIVDMDWLGA
TQGYRVTLDNDTVIDANLLVGADGRGSFVRKQAGIELDILDYNQTAICCAIQTEKPHQATARQAMLPTGTLALLPLADIT
DEDKANPQHWQSIVWTLPRNQALALIEEHPRYIADKLAAASHYELGAIYKIESIASFPLAAQQAKTYVSDNLVLIGDAAH
GVHPLAGQGLNLGMLDVKALSKQLAHDYNRSGGSLWGTNQTLRSYERLRRPHNSLMMHSFSALNWLFAGSLAQLRPIQQL
RNEGMYRVSKIKPLMRLFAKQASGV

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=445, Percent_Identity=28.5393258426966, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI32967307, Length=389, Percent_Identity=28.0205655526992, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1789273, Length=394, Percent_Identity=33.502538071066, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1786883, Length=422, Percent_Identity=32.2274881516588, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1789274, Length=423, Percent_Identity=26.241134751773, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25146631, Length=424, Percent_Identity=27.8301886792453, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321694, Length=358, Percent_Identity=27.3743016759777, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920760, Length=452, Percent_Identity=28.7610619469027, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 46989; Mature: 46989

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNHTLIIGGGIVGATLALKLAQDNKPVTLIDARPKRNEEDWQQILGQRDARVYALSLA
CCCCCEEEEECCHHEEHHEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEHHH
SIELLKEVGAWQKIAASERKADYLQMQVWQLNGVGELLFGDSTNNSDDSNQNSEPKMLGS
HHHHHHHHCHHHHHHHHHHCCHHHEEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHH
MVEPAVIEYALWQRLSATDLKQYLTVIDGQKIVDMDWLGATQGYRVTLDNDTVIDANLLV
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCEEEEEEEEE
GADGRGSFVRKQAGIELDILDYNQTAICCAIQTEKPHQATARQAMLPTGTLALLPLADIT
ECCCCCCHHHHHCCCEEEEEECCCEEEEEEEECCCCCHHHHHHHCCCCCCEEEEEECCCC
DEDKANPQHWQSIVWTLPRNQALALIEEHPRYIADKLAAASHYELGAIYKIESIASFPLA
CCCCCCHHHHHHHHEECCCCCEEHHHHHCHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCH
AQQAKTYVSDNLVLIGDAAHGVHPLAGQGLNLGMLDVKALSKQLAHDYNRSGGSLWGTNQ
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHH
TLRSYERLRRPHNSLMMHSFSALNWLFAGSLAQLRPIQQLRNEGMYRVSKIKPLMRLFAK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
QASGV
HHCCC
>Mature Secondary Structure
MKNNHTLIIGGGIVGATLALKLAQDNKPVTLIDARPKRNEEDWQQILGQRDARVYALSLA
CCCCCEEEEECCHHEEHHEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEHHH
SIELLKEVGAWQKIAASERKADYLQMQVWQLNGVGELLFGDSTNNSDDSNQNSEPKMLGS
HHHHHHHHCHHHHHHHHHHCCHHHEEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHH
MVEPAVIEYALWQRLSATDLKQYLTVIDGQKIVDMDWLGATQGYRVTLDNDTVIDANLLV
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCEEEEEEEEE
GADGRGSFVRKQAGIELDILDYNQTAICCAIQTEKPHQATARQAMLPTGTLALLPLADIT
ECCCCCCHHHHHCCCEEEEEECCCEEEEEEEECCCCCHHHHHHHCCCCCCEEEEEECCCC
DEDKANPQHWQSIVWTLPRNQALALIEEHPRYIADKLAAASHYELGAIYKIESIASFPLA
CCCCCCHHHHHHHHEECCCCCEEHHHHHCHHHHHHHHHHCCCCCCCEEEEEHHHHCCCCH
AQQAKTYVSDNLVLIGDAAHGVHPLAGQGLNLGMLDVKALSKQLAHDYNRSGGSLWGTNQ
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHH
TLRSYERLRRPHNSLMMHSFSALNWLFAGSLAQLRPIQQLRNEGMYRVSKIKPLMRLFAK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHH
QASGV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]