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The map label for this gene is etfA [H]

Identifier: 93005358

GI number: 93005358

Start: 624414

End: 625346

Strand: Direct

Name: etfA [H]

Synonym: Pcryo_0528

Alternate gene names: 93005358

Gene position: 624414-625346 (Clockwise)

Preceding gene: 93005357

Following gene: 93005361

Centisome position: 20.41

GC content: 44.91

Gene sequence:

>933_bases
ATGGCAATTTTGGTATATGCAGAACACGACAATGCCAGTCTAAAAAAGGCAACTTTGAATACGATCGCTGCTGCTCAGCA
AATTGGCGGTGATATTCATGTATTGATCGCTGGTAGTGGTGCGCAAGCAGCAGCTGACGAAGCAGCAAAAGCAGCAGGCG
TTAGCAAAGTATTACTAGCAGACAACGCAGCTTATGAGCATCAATTAGCAGGTAACTTAGCGCTATTGGTCGCTGATATT
GCTGGTGAGTACAGTCATATTCTTGCACCTGCTACAACCACTGGTAAAAATTTCTTACCACGCGTTGCCGCATTACTTGA
TGTCAGCATGTTATCAGAAATCTCTGCTGTGGTAGATGCACAAACGTTTGAGCGTCCTATCTATGCTGGTAACGCGACTG
CAACGGTTAAGACGACAGAAGATAAAGTGGTATTAACCGTACGTACCACTGCTTTTGATCCAGTAGCAAGTGAAGGTGGT
TCAGCCGCTGTTGAAACTCTTGACAATGTGCAAGAGCTTGGCAAATCAAGCTTTGTTAATGAAGAGATGGCTAAGTCTGA
CCGTCCTGAATTGACGTCAGCCAGCATCGTGGTTTCTGGTGGTCGTGCCCTAGCAAATGGTGAAAACTTCACTAAATATA
TCGAGCCATTGGCTGATAAACTTGGCGCTGCTGTTGGTGCATCACGTGCCGCTGTCGACGCAGGCTATGTACCAAACGAT
ATGCAGGTTGGTCAAACAGGTAAAATCGTTGCACCAGACTTATATATCGCAGCTGGTATTTCAGGCGCTATTCAGCATTT
AGCGGGTATGAAAGATTCTAAAGTCATCGTTGCTATCAATAATGACCCAGAATCACCTATCGCTAGCGTTGCCGATTACT
TCTTAGAAGCTGATTTATTTGCAGCCTTACCTGAACTGACCAGTAAAATCTAA

Upstream 100 bases:

>100_bases
ATGACGTCCTAAATAAGTTTTATTGAACTTGGACATAATAGGGCTTTGTGTACCAACAACCTCATGAATAGATGATACGA
ATAAATAAAGGACAAAAACA

Downstream 100 bases:

>100_bases
GTACTTGTTAGTGAAAGTAAAATAAAAAACCCGCTATCATTGATTGCGGGTTTTTTTGTATTCAACTTAAAAATCGTCTT
GCTGATTCAGTTAAATGATA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MAILVYAEHDNASLKKATLNTIAAAQQIGGDIHVLIAGSGAQAAADEAAKAAGVSKVLLADNAAYEHQLAGNLALLVADI
AGEYSHILAPATTTGKNFLPRVAALLDVSMLSEISAVVDAQTFERPIYAGNATATVKTTEDKVVLTVRTTAFDPVASEGG
SAAVETLDNVQELGKSSFVNEEMAKSDRPELTSASIVVSGGRALANGENFTKYIEPLADKLGAAVGASRAAVDAGYVPND
MQVGQTGKIVAPDLYIAAGISGAIQHLAGMKDSKVIVAINNDPESPIASVADYFLEADLFAALPELTSKI

Sequences:

>Translated_310_residues
MAILVYAEHDNASLKKATLNTIAAAQQIGGDIHVLIAGSGAQAAADEAAKAAGVSKVLLADNAAYEHQLAGNLALLVADI
AGEYSHILAPATTTGKNFLPRVAALLDVSMLSEISAVVDAQTFERPIYAGNATATVKTTEDKVVLTVRTTAFDPVASEGG
SAAVETLDNVQELGKSSFVNEEMAKSDRPELTSASIVVSGGRALANGENFTKYIEPLADKLGAAVGASRAAVDAGYVPND
MQVGQTGKIVAPDLYIAAGISGAIQHLAGMKDSKVIVAINNDPESPIASVADYFLEADLFAALPELTSKI
>Mature_309_residues
AILVYAEHDNASLKKATLNTIAAAQQIGGDIHVLIAGSGAQAAADEAAKAAGVSKVLLADNAAYEHQLAGNLALLVADIA
GEYSHILAPATTTGKNFLPRVAALLDVSMLSEISAVVDAQTFERPIYAGNATATVKTTEDKVVLTVRTTAFDPVASEGGS
AAVETLDNVQELGKSSFVNEEMAKSDRPELTSASIVVSGGRALANGENFTKYIEPLADKLGAAVGASRAAVDAGYVPNDM
QVGQTGKIVAPDLYIAAGISGAIQHLAGMKDSKVIVAINNDPESPIASVADYFLEADLFAALPELTSKI

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=56.2091503267974, Blast_Score=322, Evalue=2e-88,
Organism=Homo sapiens, GI189181759, Length=272, Percent_Identity=56.6176470588235, Blast_Score=287, Evalue=7e-78,
Organism=Escherichia coli, GI1787990, Length=295, Percent_Identity=30.8474576271186, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786226, Length=232, Percent_Identity=30.6034482758621, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082157, Length=233, Percent_Identity=30.4721030042918, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=308, Percent_Identity=54.2207792207792, Blast_Score=304, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6325261, Length=294, Percent_Identity=46.5986394557823, Blast_Score=258, Evalue=6e-70,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=58.974358974359, Blast_Score=332, Evalue=3e-91,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=58.974358974359, Blast_Score=332, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31849; Mature: 31718

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVYAEHDNASLKKATLNTIAAAQQIGGDIHVLIAGSGAQAAADEAAKAAGVSKVLLA
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEE
DNAAYEHQLAGNLALLVADIAGEYSHILAPATTTGKNFLPRVAALLDVSMLSEISAVVDA
CCCHHHHHHHCCCEEEEEHHHCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QTFERPIYAGNATATVKTTEDKVVLTVRTTAFDPVASEGGSAAVETLDNVQELGKSSFVN
HHHCCCEECCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
EEMAKSDRPELTSASIVVSGGRALANGENFTKYIEPLADKLGAAVGASRAAVDAGYVPND
HHHHHCCCCCCCEEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
MQVGQTGKIVAPDLYIAAGISGAIQHLAGMKDSKVIVAINNDPESPIASVADYFLEADLF
CEECCCCCEECCCHHEECCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
AALPELTSKI
HHHHHHHHCC
>Mature Secondary Structure 
AILVYAEHDNASLKKATLNTIAAAQQIGGDIHVLIAGSGAQAAADEAAKAAGVSKVLLA
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEE
DNAAYEHQLAGNLALLVADIAGEYSHILAPATTTGKNFLPRVAALLDVSMLSEISAVVDA
CCCHHHHHHHCCCEEEEEHHHCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QTFERPIYAGNATATVKTTEDKVVLTVRTTAFDPVASEGGSAAVETLDNVQELGKSSFVN
HHHCCCEECCCCEEEEEECCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
EEMAKSDRPELTSASIVVSGGRALANGENFTKYIEPLADKLGAAVGASRAAVDAGYVPND
HHHHHCCCCCCCEEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
MQVGQTGKIVAPDLYIAAGISGAIQHLAGMKDSKVIVAINNDPESPIASVADYFLEADLF
CEECCCCCEECCCHHEECCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
AALPELTSKI
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]