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The map label for this gene is mreB [H]

Identifier: 93005308

GI number: 93005308

Start: 586931

End: 587959

Strand: Direct

Name: mreB [H]

Synonym: Pcryo_0478

Alternate gene names: 93005308

Gene position: 586931-587959 (Clockwise)

Preceding gene: 93005302

Following gene: 93005309

Centisome position: 19.18

GC content: 47.81

Gene sequence:

>1029_bases
ATGAACCTGTTTGGATTTTTATCAAATAATATCGCAATCGACCTCGGTACTGCGAACACCCTTATTTTTATTCCTGGTAA
AGGCGTGGTGCTCGATGAGCCTACGGTGGTCGCTTTAAGAAGCAATCGCACACAGAACCCTACCGTTGCTGCTGTTGGTA
TTGATGCCAAGCAGATGCTGGGTCGTACGCCTGCCAATATTACGGCTATCCGCCCTTTAAAAGACGGCGTGATTGCTGAC
TTTGAAGTGACGCAAAAAATGCTTAAGCATTTTATCGCCAAGGTAAAAGCTAAGCGTTTTATGGCACAGCCTAATGTGGT
GGTTTGCGTGCCCTGCAAGTCTACCCTTGTCGAGCGAAAAGCGATTCGTGAAGCGGTATCGTCAGCTGGCGCCAGCAAAG
TATTGTTACTAGAAGAGCCAATGGCAGCAGCGATTGGTGCTGGCATGCCGGTTCATGAAGCCAGCGGTTCGATGGTCGTT
GATATCGGCGGTGGTACCACTGAGATTGCCGTTATCGCTTTGTCAGGTTGTGTCTATGCTGAGTCTATCCGTATCGGTGG
CGATATGTTTGATGATGCCATTATTACCCATGTACGTCGTATTCATGGCTGCGTGATTGGTGAAACCACGGCTGAGCGTA
TCAAACAAGAAGTTGGCTCCGCGCTAAATGAAGACAGCCAGTTAGAAGTAGAAGTACGCGGACGTAGCATGGCAGAAGGC
GTACCAAAAACCTTCACTGTCAACTCAGAAGAAGTGCAGAAAGCTTTGAGTGATCCGTTAAGTGGTATCGTCAGCGCGGT
AAAAGCAGCACTTGAGCAGACGCCACCAGAGTTGTCATCAGATATCGCTGAACGCGGTATTGTCTTGACTGGGGGCGGCG
CACTATTACGTGACCTAGATAAGCTCATCTCAAGAGAGACAGGCTTACCAGTTACAGTCGCTGAAGATCCATTAACTTGC
GTGAGCCGTGGTGGTGGTATTGCGCTTGATTTTATCAATAACAAAAGCCTAAATATGATTTTTGTATAA

Upstream 100 bases:

>100_bases
TCGCCACGGGTAATGTCTAAAGACGACCTGCTCAATACTGACGAGTAATCCCTCGGTCACTCTCATTTGCCTCATTTGTA
ATACGCTGGAAATATTAGTC

Downstream 100 bases:

>100_bases
ATCACTGTTTATCAAGCATTGTCATACTAGCAATGTTAGATAAGGCTGAAGTTAACGATAACTAGGCATGAGAAAGGGTA
GATGAATAACATTGAAGGTA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNLFGFLSNNIAIDLGTANTLIFIPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQMLGRTPANITAIRPLKDGVIAD
FEVTQKMLKHFIAKVKAKRFMAQPNVVVCVPCKSTLVERKAIREAVSSAGASKVLLLEEPMAAAIGAGMPVHEASGSMVV
DIGGGTTEIAVIALSGCVYAESIRIGGDMFDDAIITHVRRIHGCVIGETTAERIKQEVGSALNEDSQLEVEVRGRSMAEG
VPKTFTVNSEEVQKALSDPLSGIVSAVKAALEQTPPELSSDIAERGIVLTGGGALLRDLDKLISRETGLPVTVAEDPLTC
VSRGGGIALDFINNKSLNMIFV

Sequences:

>Translated_342_residues
MNLFGFLSNNIAIDLGTANTLIFIPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQMLGRTPANITAIRPLKDGVIAD
FEVTQKMLKHFIAKVKAKRFMAQPNVVVCVPCKSTLVERKAIREAVSSAGASKVLLLEEPMAAAIGAGMPVHEASGSMVV
DIGGGTTEIAVIALSGCVYAESIRIGGDMFDDAIITHVRRIHGCVIGETTAERIKQEVGSALNEDSQLEVEVRGRSMAEG
VPKTFTVNSEEVQKALSDPLSGIVSAVKAALEQTPPELSSDIAERGIVLTGGGALLRDLDKLISRETGLPVTVAEDPLTC
VSRGGGIALDFINNKSLNMIFV
>Mature_342_residues
MNLFGFLSNNIAIDLGTANTLIFIPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQMLGRTPANITAIRPLKDGVIAD
FEVTQKMLKHFIAKVKAKRFMAQPNVVVCVPCKSTLVERKAIREAVSSAGASKVLLLEEPMAAAIGAGMPVHEASGSMVV
DIGGGTTEIAVIALSGCVYAESIRIGGDMFDDAIITHVRRIHGCVIGETTAERIKQEVGSALNEDSQLEVEVRGRSMAEG
VPKTFTVNSEEVQKALSDPLSGIVSAVKAALEQTPPELSSDIAERGIVLTGGGALLRDLDKLISRETGLPVTVAEDPLTC
VSRGGGIALDFINNKSLNMIFV

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=359, Percent_Identity=24.2339832869081, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI16507237, Length=339, Percent_Identity=23.8938053097345, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI24234686, Length=220, Percent_Identity=25.9090909090909, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI5729877, Length=220, Percent_Identity=25.9090909090909, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082236, Length=331, Percent_Identity=67.0694864048338, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1786870, Length=356, Percent_Identity=24.7191011235955, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36025; Mature: 36025

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFGFLSNNIAIDLGTANTLIFIPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQML
CCCEEEECCCEEEEECCCCEEEEECCCCEEECCCEEEEEECCCCCCCEEEEEECCHHHHH
GRTPANITAIRPLKDGVIADFEVTQKMLKHFIAKVKAKRFMAQPNVVVCVPCKSTLVERK
CCCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
AIREAVSSAGASKVLLLEEPMAAAIGAGMPVHEASGSMVVDIGGGTTEIAVIALSGCVYA
HHHHHHHHCCCCEEEEECCCHHHHHCCCCCEECCCCCEEEEECCCCCEEEEEEEECCEEE
ESIRIGGDMFDDAIITHVRRIHGCVIGETTAERIKQEVGSALNEDSQLEVEVRGRSMAEG
EEEECCCCHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCC
VPKTFTVNSEEVQKALSDPLSGIVSAVKAALEQTPPELSSDIAERGIVLTGGGALLRDLD
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCCHHHHHHH
KLISRETGLPVTVAEDPLTCVSRGGGIALDFINNKSLNMIFV
HHHHHCCCCEEEECCCCHHHHHCCCCEEEEEECCCCEEEEEC
>Mature Secondary Structure
MNLFGFLSNNIAIDLGTANTLIFIPGKGVVLDEPTVVALRSNRTQNPTVAAVGIDAKQML
CCCEEEECCCEEEEECCCCEEEEECCCCEEECCCEEEEEECCCCCCCEEEEEECCHHHHH
GRTPANITAIRPLKDGVIADFEVTQKMLKHFIAKVKAKRFMAQPNVVVCVPCKSTLVERK
CCCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
AIREAVSSAGASKVLLLEEPMAAAIGAGMPVHEASGSMVVDIGGGTTEIAVIALSGCVYA
HHHHHHHHCCCCEEEEECCCHHHHHCCCCCEECCCCCEEEEECCCCCEEEEEEEECCEEE
ESIRIGGDMFDDAIITHVRRIHGCVIGETTAERIKQEVGSALNEDSQLEVEVRGRSMAEG
EEEECCCCHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHCC
VPKTFTVNSEEVQKALSDPLSGIVSAVKAALEQTPPELSSDIAERGIVLTGGGALLRDLD
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEECCCHHHHHHH
KLISRETGLPVTVAEDPLTCVSRGGGIALDFINNKSLNMIFV
HHHHHCCCCEEEECCCCHHHHHCCCCEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]