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The map label for this gene is dapL [H]

Identifier: 93005269

GI number: 93005269

Start: 537652

End: 538890

Strand: Reverse

Name: dapL [H]

Synonym: Pcryo_0439

Alternate gene names: 93005269

Gene position: 538890-537652 (Counterclockwise)

Preceding gene: 93005271

Following gene: 93005268

Centisome position: 17.61

GC content: 47.86

Gene sequence:

>1239_bases
ATGAATCACAACTTGACGTCCCTACACCCTTATCCATTCGCTAAGATGGCCACTTTACTGGCTGATAGTACTCCAGCCCA
TAGCTATGATGAAATCAAACTGGGTATTGGTGAGCCAAAACATGCGCCGCCAGCCTTTGTTCTGGACGTACTACGCGAAA
ACTTGGACAAAATAAGCCATTATCCGACCACAAATGGACTGTTTGAGCTGCGTCAAACCATTGCTCATTGGCTTGAGAAG
CGCTTTTTCTTAAATCACCTCAACCCTAATACGCAAGTATTGCCAGTAATGGGCACACGTGAGGCAATATTTAGTATCGT
GCAGGCAGTGATTAATCACGAGACAGAGACTGTTAGTCAGACGGCAACGCTCAACCAATCGCCTACTCCTACGCCTATAG
TAGTTATGCCCAATCCCTTTTATCAGATATATGAAGGGGCGGCGATATTAGCGCAAGCAACGCCTTATTTTATCCCTTGC
ACCTCAGACAATAGCTTTAAGGGGGATTTTCGTAGTGTGCCAAAAGACGTCTGGACGCGTACACAGCTCTTATTTGTCTG
TAGCCCAAACAACCCAACCGGTTCAGTGATGACGATGGATGACTGGGAGCAAGTGTTGCGCCTATCAGACCAATATGGCT
TTATCATTGCCAGCGACGAGTGTTATAGCGAGCTGTATTTTGATAAAGCGCCAATAGGATTGTTGCAAGCCTGCGCGGCC
CTTGGTCGACACGATTTCAAAAATTGTCTGGTGTTTCACTCTTTATCGAAGCGCTCAAACCTACCCGGTTTGCGCTCAGG
CTTTGTGGCAGGCGATGCCACTATCTTGCAGGCTTATTTACAATACCGCACCTATCAGGGTTGTGCGATGCCGATACCTC
ATCAGCTGGCGTCTATCGCCGCTTGGGAAGATGAGAAGCATGTGGCGCACAATCGAGCGCTGTATCAAGAAAAGTTTGCA
CTCTGGATGTCGGAGCTTGGAGAATTACTGGAGTTACGTATGCCTGAGGCAGGATTTTACTTTTGGATAAAGGCGCCTGA
GCAATTCGGTGGTGATGATGAATTATTTGTCAAAGCACTCTATGAGGATGCCAATATTCATGCACTAGCGGGTCGTTACT
TATCGCGCGAGGTCAATGGTGAAAATCCGGGGCAAGGCTATGTGCGTATCGCTTTGGTGGCAAGCGTCGAGGAAAGTCGC
GAGGCAATCAGGCGCATTCGTCAATTACTCGGTGCTTAA

Upstream 100 bases:

>100_bases
TAAGAAGAAAAAGACAAAAAATAAGAGAAGTGCTACACTGCTTAAATGTAATTTTTCTTTATAACTTTATTATTAACTGT
CTATTATAGTTAGCCTGCCT

Downstream 100 bases:

>100_bases
AATCGCTATTTAAAACGCATTAAGCTTAACAAACCGCCAATAACCATAATATAATTATGGTTATTGGCGGTTTTCTGTTA
GATGATGCTATAGTAAGTCT

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MNHNLTSLHPYPFAKMATLLADSTPAHSYDEIKLGIGEPKHAPPAFVLDVLRENLDKISHYPTTNGLFELRQTIAHWLEK
RFFLNHLNPNTQVLPVMGTREAIFSIVQAVINHETETVSQTATLNQSPTPTPIVVMPNPFYQIYEGAAILAQATPYFIPC
TSDNSFKGDFRSVPKDVWTRTQLLFVCSPNNPTGSVMTMDDWEQVLRLSDQYGFIIASDECYSELYFDKAPIGLLQACAA
LGRHDFKNCLVFHSLSKRSNLPGLRSGFVAGDATILQAYLQYRTYQGCAMPIPHQLASIAAWEDEKHVAHNRALYQEKFA
LWMSELGELLELRMPEAGFYFWIKAPEQFGGDDELFVKALYEDANIHALAGRYLSREVNGENPGQGYVRIALVASVEESR
EAIRRIRQLLGA

Sequences:

>Translated_412_residues
MNHNLTSLHPYPFAKMATLLADSTPAHSYDEIKLGIGEPKHAPPAFVLDVLRENLDKISHYPTTNGLFELRQTIAHWLEK
RFFLNHLNPNTQVLPVMGTREAIFSIVQAVINHETETVSQTATLNQSPTPTPIVVMPNPFYQIYEGAAILAQATPYFIPC
TSDNSFKGDFRSVPKDVWTRTQLLFVCSPNNPTGSVMTMDDWEQVLRLSDQYGFIIASDECYSELYFDKAPIGLLQACAA
LGRHDFKNCLVFHSLSKRSNLPGLRSGFVAGDATILQAYLQYRTYQGCAMPIPHQLASIAAWEDEKHVAHNRALYQEKFA
LWMSELGELLELRMPEAGFYFWIKAPEQFGGDDELFVKALYEDANIHALAGRYLSREVNGENPGQGYVRIALVASVEESR
EAIRRIRQLLGA
>Mature_412_residues
MNHNLTSLHPYPFAKMATLLADSTPAHSYDEIKLGIGEPKHAPPAFVLDVLRENLDKISHYPTTNGLFELRQTIAHWLEK
RFFLNHLNPNTQVLPVMGTREAIFSIVQAVINHETETVSQTATLNQSPTPTPIVVMPNPFYQIYEGAAILAQATPYFIPC
TSDNSFKGDFRSVPKDVWTRTQLLFVCSPNNPTGSVMTMDDWEQVLRLSDQYGFIIASDECYSELYFDKAPIGLLQACAA
LGRHDFKNCLVFHSLSKRSNLPGLRSGFVAGDATILQAYLQYRTYQGCAMPIPHQLASIAAWEDEKHVAHNRALYQEKFA
LWMSELGELLELRMPEAGFYFWIKAPEQFGGDDELFVKALYEDANIHALAGRYLSREVNGENPGQGYVRIALVASVEESR
EAIRRIRQLLGA

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=290, Percent_Identity=23.7931034482759, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI56713254, Length=290, Percent_Identity=23.7931034482759, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI95147551, Length=307, Percent_Identity=21.8241042345277, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI169881279, Length=307, Percent_Identity=21.8241042345277, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1788722, Length=419, Percent_Identity=24.582338902148, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1788627, Length=243, Percent_Identity=23.8683127572016, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=268, Percent_Identity=23.5074626865672, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=352, Percent_Identity=22.7272727272727, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573069, Length=347, Percent_Identity=23.342939481268, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646114, Length=347, Percent_Identity=23.342939481268, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573067, Length=347, Percent_Identity=23.342939481268, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573065, Length=347, Percent_Identity=23.342939481268, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 46371; Mature: 46371

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHNLTSLHPYPFAKMATLLADSTPAHSYDEIKLGIGEPKHAPPAFVLDVLRENLDKISH
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHC
YPTTNGLFELRQTIAHWLEKRFFLNHLNPNTQVLPVMGTREAIFSIVQAVINHETETVSQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHH
TATLNQSPTPTPIVVMPNPFYQIYEGAAILAQATPYFIPCTSDNSFKGDFRSVPKDVWTR
HHCCCCCCCCCEEEECCCCHHHHHCCCEEEEECCCEEEECCCCCCCCCHHHHCCHHHHCC
TQLLFVCSPNNPTGSVMTMDDWEQVLRLSDQYGFIIASDECYSELYFDKAPIGLLQACAA
EEEEEEECCCCCCCCEEEHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHH
LGRHDFKNCLVFHSLSKRSNLPGLRSGFVAGDATILQAYLQYRTYQGCAMPIPHQLASIA
HHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AWEDEKHVAHNRALYQEKFALWMSELGELLELRMPEAGFYFWIKAPEQFGGDDELFVKAL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCHHHHHHHH
YEDANIHALAGRYLSREVNGENPGQGYVRIALVASVEESREAIRRIRQLLGA
HCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHNLTSLHPYPFAKMATLLADSTPAHSYDEIKLGIGEPKHAPPAFVLDVLRENLDKISH
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHC
YPTTNGLFELRQTIAHWLEKRFFLNHLNPNTQVLPVMGTREAIFSIVQAVINHETETVSQ
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHH
TATLNQSPTPTPIVVMPNPFYQIYEGAAILAQATPYFIPCTSDNSFKGDFRSVPKDVWTR
HHCCCCCCCCCEEEECCCCHHHHHCCCEEEEECCCEEEECCCCCCCCCHHHHCCHHHHCC
TQLLFVCSPNNPTGSVMTMDDWEQVLRLSDQYGFIIASDECYSELYFDKAPIGLLQACAA
EEEEEEECCCCCCCCEEEHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCHHHHHHHHH
LGRHDFKNCLVFHSLSKRSNLPGLRSGFVAGDATILQAYLQYRTYQGCAMPIPHQLASIA
HHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AWEDEKHVAHNRALYQEKFALWMSELGELLELRMPEAGFYFWIKAPEQFGGDDELFVKAL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCHHHHHHHH
YEDANIHALAGRYLSREVNGENPGQGYVRIALVASVEESREAIRRIRQLLGA
HCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA