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The map label for this gene is tas [H]

Identifier: 93005228

GI number: 93005228

Start: 483654

End: 484694

Strand: Reverse

Name: tas [H]

Synonym: Pcryo_0398

Alternate gene names: 93005228

Gene position: 484694-483654 (Counterclockwise)

Preceding gene: 93005229

Following gene: 93005226

Centisome position: 15.84

GC content: 44.28

Gene sequence:

>1041_bases
ATGCAATATCAAACACTGCCGCAACTCAATGAAAAAGTCTCCAAAATCTGCTTGGGAACGATGACGTGGGGACAGCAAAA
TAGCGAAAGCGATGCACATGAGCAGATGGACCTAGCACTCAGTGAAGGCGTAAATTTTTGGGATACTGCTGAGATGTATC
CCTCACCGCCAGATAAAGATAAGCAAGGCGATACTGAGCGCTTTATGGGCACATGGTTCCAAAAGACCAAACAACGCGAT
AAAGTCGTTCTTGCCAGTAAGATATCGCCAATGGATTTTTTACGTGATGGGCAAACGCGTTTTAATGCCGCGCATATCAG
CAGTGCTATTGATGGCAATCTTGAGCGTTTGCAGACCGATTATATTGATATCTACCAACTACACTGGCCTGAACGTCAAA
CGAACTATTTCAGTCAGCTCGGTTATACCAAAGCAATGGCAGCACAGCCGCTCGATGATTTGACGCCTTTTTTAGAAACC
ATCCAAGCGTTAAATGACGAGATTAAAAAAGGTCGTATCCGTGCTTATGGATTATCAAACGATACTGCTTGGGGATTGAT
GCGCTACTTATGGGAAGCGGATAAGAATGGTTTGATCGCACCTATTACGGTGCAAAACCCTTATAGTTTGCTTAACCGCT
TATATGAAGTGGCTATGGCAGAGATTGCGCATCGTGAAAATGTGGGTTTACTTGCTTATTCACCACTAGGCTTTGGTGTG
CTATCTGGTAAGTATCTCGATGGTAAACGTCCTACTGGCGCGCGCTTGACCATGTATGATCGCTTTGCCCGTTATACTAA
TGAAGAAGCACTATCAGCCACCGCCCAATATGCCAAAATCGCAGATGATACCGGTTTAGATATGGCGCAAATGGCATTAG
CCTTTGTTAACTCACGCTCGTTTGTAACCAGCAATATCATTGGCGCGACCACCATTGAGCAGCTAAAATCTAACATTGAT
AGCATTAACTTAACCTTAGACTCAGATGTACTAGACGCTATCGAAGCGGTACATACTCAACAACCTAATCCTTCACCATA
G

Upstream 100 bases:

>100_bases
TTAAAATTAAAATCTTTCAAGTGACGCCGCCGGGTGTCACAGGCATCAAGCTCATGTAATATAAAAATTGCTTTAGAATA
AAATAAAAAAGGAAGAACAT

Downstream 100 bases:

>100_bases
TTGATGCTTATTAGACTTTTTATAAATAGAGTCATTCTATTTTCTTCAAAAAAGATACAAGTATCTATCAGTTAAAAAAA
GGCGCAAATCGCAAGTATTA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MQYQTLPQLNEKVSKICLGTMTWGQQNSESDAHEQMDLALSEGVNFWDTAEMYPSPPDKDKQGDTERFMGTWFQKTKQRD
KVVLASKISPMDFLRDGQTRFNAAHISSAIDGNLERLQTDYIDIYQLHWPERQTNYFSQLGYTKAMAAQPLDDLTPFLET
IQALNDEIKKGRIRAYGLSNDTAWGLMRYLWEADKNGLIAPITVQNPYSLLNRLYEVAMAEIAHRENVGLLAYSPLGFGV
LSGKYLDGKRPTGARLTMYDRFARYTNEEALSATAQYAKIADDTGLDMAQMALAFVNSRSFVTSNIIGATTIEQLKSNID
SINLTLDSDVLDAIEAVHTQQPNPSP

Sequences:

>Translated_346_residues
MQYQTLPQLNEKVSKICLGTMTWGQQNSESDAHEQMDLALSEGVNFWDTAEMYPSPPDKDKQGDTERFMGTWFQKTKQRD
KVVLASKISPMDFLRDGQTRFNAAHISSAIDGNLERLQTDYIDIYQLHWPERQTNYFSQLGYTKAMAAQPLDDLTPFLET
IQALNDEIKKGRIRAYGLSNDTAWGLMRYLWEADKNGLIAPITVQNPYSLLNRLYEVAMAEIAHRENVGLLAYSPLGFGV
LSGKYLDGKRPTGARLTMYDRFARYTNEEALSATAQYAKIADDTGLDMAQMALAFVNSRSFVTSNIIGATTIEQLKSNID
SINLTLDSDVLDAIEAVHTQQPNPSP
>Mature_346_residues
MQYQTLPQLNEKVSKICLGTMTWGQQNSESDAHEQMDLALSEGVNFWDTAEMYPSPPDKDKQGDTERFMGTWFQKTKQRD
KVVLASKISPMDFLRDGQTRFNAAHISSAIDGNLERLQTDYIDIYQLHWPERQTNYFSQLGYTKAMAAQPLDDLTPFLET
IQALNDEIKKGRIRAYGLSNDTAWGLMRYLWEADKNGLIAPITVQNPYSLLNRLYEVAMAEIAHRENVGLLAYSPLGFGV
LSGKYLDGKRPTGARLTMYDRFARYTNEEALSATAQYAKIADDTGLDMAQMALAFVNSRSFVTSNIIGATTIEQLKSNID
SINLTLDSDVLDAIEAVHTQQPNPSP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=352, Percent_Identity=27.5568181818182, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436962, Length=352, Percent_Identity=27.5568181818182, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436966, Length=352, Percent_Identity=27.2727272727273, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI27436969, Length=352, Percent_Identity=28.4090909090909, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4504825, Length=350, Percent_Identity=28.2857142857143, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436971, Length=337, Percent_Identity=26.4094955489614, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI41327764, Length=335, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI223718702, Length=347, Percent_Identity=23.9193083573487, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI41152114, Length=349, Percent_Identity=24.0687679083095, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=49.7142857142857, Blast_Score=346, Evalue=1e-96,
Organism=Escherichia coli, GI87081735, Length=360, Percent_Identity=29.1666666666667, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=26.9461077844311, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789375, Length=353, Percent_Identity=24.929178470255, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=324, Percent_Identity=24.0740740740741, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=355, Percent_Identity=24.2253521126761, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=344, Percent_Identity=24.4186046511628, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=342, Percent_Identity=23.3918128654971, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=270, Percent_Identity=22.962962962963, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38920; Mature: 38920

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYQTLPQLNEKVSKICLGTMTWGQQNSESDAHEQMDLALSEGVNFWDTAEMYPSPPDKD
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KQGDTERFMGTWFQKTKQRDKVVLASKISPMDFLRDGQTRFNAAHISSAIDGNLERLQTD
CCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHH
YIDIYQLHWPERQTNYFSQLGYTKAMAAQPLDDLTPFLETIQALNDEIKKGRIRAYGLSN
HEEEEEEECCCHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
DTAWGLMRYLWEADKNGLIAPITVQNPYSLLNRLYEVAMAEIAHRENVGLLAYSPLGFGV
CHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHH
LSGKYLDGKRPTGARLTMYDRFARYTNEEALSATAQYAKIADDTGLDMAQMALAFVNSRS
HCCCEECCCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
FVTSNIIGATTIEQLKSNIDSINLTLDSDVLDAIEAVHTQQPNPSP
HHHHHCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQYQTLPQLNEKVSKICLGTMTWGQQNSESDAHEQMDLALSEGVNFWDTAEMYPSPPDKD
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
KQGDTERFMGTWFQKTKQRDKVVLASKISPMDFLRDGQTRFNAAHISSAIDGNLERLQTD
CCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHH
YIDIYQLHWPERQTNYFSQLGYTKAMAAQPLDDLTPFLETIQALNDEIKKGRIRAYGLSN
HEEEEEEECCCHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
DTAWGLMRYLWEADKNGLIAPITVQNPYSLLNRLYEVAMAEIAHRENVGLLAYSPLGFGV
CHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHH
LSGKYLDGKRPTGARLTMYDRFARYTNEEALSATAQYAKIADDTGLDMAQMALAFVNSRS
HCCCEECCCCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
FVTSNIIGATTIEQLKSNIDSINLTLDSDVLDAIEAVHTQQPNPSP
HHHHHCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]