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The map label for this gene is hflX [H]

Identifier: 93005226

GI number: 93005226

Start: 480798

End: 482267

Strand: Reverse

Name: hflX [H]

Synonym: Pcryo_0396

Alternate gene names: 93005226

Gene position: 482267-480798 (Counterclockwise)

Preceding gene: 93005228

Following gene: 93005225

Centisome position: 15.76

GC content: 46.94

Gene sequence:

>1470_bases
TTGGAATATTTTGAAAGACATACCGGTGGCGAGCGCGCCATCATTGTACATTTAGACATCCGCCAAATTCAAGATCCTGA
TGATTTAGGGGAATTTGAATTATTGGCAGACTCAGCAGGCGCAGACCGCTTGGCACTGGTCACAGGCTCACGTGCACGCC
CTGACGCCAGATATTTTGTTGGTAGCGGCAAAGCAGAAGAGATAGCAGAACTGGTGCGCGAGCATGATGCGGACATCGTG
CTTTTTAACCACAGCTTATCGCCTTCACAAGAGCGTAACATTGAAGCCTTGGTACAATGCCGCGTACTTGATCGCACGGG
TCTGATTTTGGACATTTTCGCGCAGCGTGCACGTACTTACGAAGGTAAGCTACAAGTAGAGCTGGCACAGCTTAACCATT
TGTCGACACGTTTGGTACGTGGTTGGACGCATTTGGAACGTCAAAAAGGGGGTATTGGTCTACGTGGACCCGGTGAAACC
CAGCTTGAGACGGATCGTCGCTTGCTACAAGTGCGAGTCATGCAGCTCAAAAGTAGAATCGAAAAAGTCAGACAGACGCG
TGCGCAAGGTCGAGCTCGCCGTCAAAAATCAGATGTACCGACTATTTCGCTTGTGGGTTATACCAATGCTGGTAAGTCTA
CTTTGTTTAATCGCTTGGTCGATGAAAACATTTATGCGGCCGACAAACTGTTTGCGACACTCGATCCGACGTTACGCCGC
TTAGATTGGCAAGGTGTAGGACGTGTGGTACTGGTCGACACAGTAGGTTTTGTCCGTCATCTTCCACATGAATTGGTTGA
ATCTTTCCATGCGACCTTAGAAGAGACACTTGAAGCAGACCTATTGCTCCATGTCATCGATTCTTCGAGCGAAGACATGC
ATGAGCAAATTCAGGCGGTGAAAGATGTACTGGCTGAAATTGATAATGATGTGCCTGTGCTTAATGTCTACAACAAGATT
GATGTGACCGATGAGCCTGCACGTATCGGTTATGCTAGCGAAGGTCAACCCAACCGCGTCTATGTTTCTTCTAGAGAAAA
CTTAGGCATGGAAGAGTTGTCATTGGCCGTGCAGCAATTACTAACTGGCACACTGACCACCTTTGATTTGACCCTACCTT
ATAGCGCAGGGCAGTTAAAAAATGCTTTGTATGAGCTCGGCGTTATTCAAGAAGAAAGCTATGATGACAGTGGTCATGAG
TGCTTAACGATTCGCTTGCCAAGCGATAGACTGAGACAGTTACTTGGTCAAGCCAACTTAGAGCCTCTAGATGTATTGCC
ATTAGCGCAAGCAACATTGCTGATGCCGATACTTGAAGAGTTTGAGCAGCCTGATGATGTGGAAGAACAAACGATGACGG
ATGCTGAAGAAAAAGCGTTTGCTGAATTTGAGGCGTTAAATGCTGAAGCTGAGAGAGTAGCGGAAGACTTGCTGATAGAA
GATACTCAAACATCCGACTTGCAAAAATAA

Upstream 100 bases:

>100_bases
TGTATTGAATAAAACCCAAATATTTAGAAGTGATATTTAGAACTGGTATTTAGAATAGGCAGCGTTGCGATTTATTTACT
TTATGGATAGGTGATACTCT

Downstream 100 bases:

>100_bases
GTCATTTACTTAACATACTTTGAATAAAATTAAAAAGGACGCTATTTATTAATAGTGTCCTTTTTAATGCTGAATCAACA
TAGCGTACAAGAGAAACTCG

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MEYFERHTGGERAIIVHLDIRQIQDPDDLGEFELLADSAGADRLALVTGSRARPDARYFVGSGKAEEIAELVREHDADIV
LFNHSLSPSQERNIEALVQCRVLDRTGLILDIFAQRARTYEGKLQVELAQLNHLSTRLVRGWTHLERQKGGIGLRGPGET
QLETDRRLLQVRVMQLKSRIEKVRQTRAQGRARRQKSDVPTISLVGYTNAGKSTLFNRLVDENIYAADKLFATLDPTLRR
LDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSEDMHEQIQAVKDVLAEIDNDVPVLNVYNKI
DVTDEPARIGYASEGQPNRVYVSSRENLGMEELSLAVQQLLTGTLTTFDLTLPYSAGQLKNALYELGVIQEESYDDSGHE
CLTIRLPSDRLRQLLGQANLEPLDVLPLAQATLLMPILEEFEQPDDVEEQTMTDAEEKAFAEFEALNAEAERVAEDLLIE
DTQTSDLQK

Sequences:

>Translated_489_residues
MEYFERHTGGERAIIVHLDIRQIQDPDDLGEFELLADSAGADRLALVTGSRARPDARYFVGSGKAEEIAELVREHDADIV
LFNHSLSPSQERNIEALVQCRVLDRTGLILDIFAQRARTYEGKLQVELAQLNHLSTRLVRGWTHLERQKGGIGLRGPGET
QLETDRRLLQVRVMQLKSRIEKVRQTRAQGRARRQKSDVPTISLVGYTNAGKSTLFNRLVDENIYAADKLFATLDPTLRR
LDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSEDMHEQIQAVKDVLAEIDNDVPVLNVYNKI
DVTDEPARIGYASEGQPNRVYVSSRENLGMEELSLAVQQLLTGTLTTFDLTLPYSAGQLKNALYELGVIQEESYDDSGHE
CLTIRLPSDRLRQLLGQANLEPLDVLPLAQATLLMPILEEFEQPDDVEEQTMTDAEEKAFAEFEALNAEAERVAEDLLIE
DTQTSDLQK
>Mature_489_residues
MEYFERHTGGERAIIVHLDIRQIQDPDDLGEFELLADSAGADRLALVTGSRARPDARYFVGSGKAEEIAELVREHDADIV
LFNHSLSPSQERNIEALVQCRVLDRTGLILDIFAQRARTYEGKLQVELAQLNHLSTRLVRGWTHLERQKGGIGLRGPGET
QLETDRRLLQVRVMQLKSRIEKVRQTRAQGRARRQKSDVPTISLVGYTNAGKSTLFNRLVDENIYAADKLFATLDPTLRR
LDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSEDMHEQIQAVKDVLAEIDNDVPVLNVYNKI
DVTDEPARIGYASEGQPNRVYVSSRENLGMEELSLAVQQLLTGTLTTFDLTLPYSAGQLKNALYELGVIQEESYDDSGHE
CLTIRLPSDRLRQLLGQANLEPLDVLPLAQATLLMPILEEFEQPDDVEEQTMTDAEEKAFAEFEALNAEAERVAEDLLIE
DTQTSDLQK

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=265, Percent_Identity=34.7169811320755, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI310133116, Length=221, Percent_Identity=37.10407239819, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI310124269, Length=203, Percent_Identity=37.9310344827586, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124267, Length=203, Percent_Identity=37.9310344827586, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124171, Length=203, Percent_Identity=37.9310344827586, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124169, Length=203, Percent_Identity=37.9310344827586, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1790615, Length=417, Percent_Identity=57.7937649880096, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17561038, Length=277, Percent_Identity=30.6859205776173, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24650079, Length=371, Percent_Identity=30.188679245283, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 54994; Mature: 54994

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYFERHTGGERAIIVHLDIRQIQDPDDLGEFELLADSAGADRLALVTGSRARPDARYFV
CCCHHHCCCCCEEEEEEEEHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCEEEE
GSGKAEEIAELVREHDADIVLFNHSLSPSQERNIEALVQCRVLDRTGLILDIFAQRARTY
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCC
EGKLQVELAQLNHLSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLQVRVMQLKSRI
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EKVRQTRAQGRARRQKSDVPTISLVGYTNAGKSTLFNRLVDENIYAADKLFATLDPTLRR
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCHHHHH
LDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSEDMHEQIQAV
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KDVLAEIDNDVPVLNVYNKIDVTDEPARIGYASEGQPNRVYVSSRENLGMEELSLAVQQL
HHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
LTGTLTTFDLTLPYSAGQLKNALYELGVIQEESYDDSGHECLTIRLPSDRLRQLLGQANL
HHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCC
EPLDVLPLAQATLLMPILEEFEQPDDVEEQTMTDAEEKAFAEFEALNAEAERVAEDLLIE
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCC
DTQTSDLQK
CCCCCCCCC
>Mature Secondary Structure
MEYFERHTGGERAIIVHLDIRQIQDPDDLGEFELLADSAGADRLALVTGSRARPDARYFV
CCCHHHCCCCCEEEEEEEEHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCEEEE
GSGKAEEIAELVREHDADIVLFNHSLSPSQERNIEALVQCRVLDRTGLILDIFAQRARTY
CCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCC
EGKLQVELAQLNHLSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLQVRVMQLKSRI
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EKVRQTRAQGRARRQKSDVPTISLVGYTNAGKSTLFNRLVDENIYAADKLFATLDPTLRR
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCHHHHH
LDWQGVGRVVLVDTVGFVRHLPHELVESFHATLEETLEADLLLHVIDSSSEDMHEQIQAV
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KDVLAEIDNDVPVLNVYNKIDVTDEPARIGYASEGQPNRVYVSSRENLGMEELSLAVQQL
HHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
LTGTLTTFDLTLPYSAGQLKNALYELGVIQEESYDDSGHECLTIRLPSDRLRQLLGQANL
HHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCC
EPLDVLPLAQATLLMPILEEFEQPDDVEEQTMTDAEEKAFAEFEALNAEAERVAEDLLIE
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCC
DTQTSDLQK
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]