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The map label for this gene is degP [H]

Identifier: 93004988

GI number: 93004988

Start: 187074

End: 188531

Strand: Direct

Name: degP [H]

Synonym: Pcryo_0157

Alternate gene names: 93004988

Gene position: 187074-188531 (Clockwise)

Preceding gene: 93004986

Following gene: 93004989

Centisome position: 6.11

GC content: 47.19

Gene sequence:

>1458_bases
ATGCCAATCGACATATCTAAATCGAAAATCACCATAGCTACCATGCAGCGCTTGCTTCAACGCAGCACCTTGGCAATCGC
TGTCGCTACTACCATGGTTGTTGGTATTAATCTCAACACTATGCCAAGTGCGCAAGCTGCTGTCACCACAGCGGATTTTT
CAGGATTGGTACAGCAAGTCACGCCAGCGGTGGCACGCGTCAATGTGACCAAAACTGTGAGTGAGGCTGAGCTTGCAAAA
GCCCAAACGGCTGAGCTGTTACGGAAATTCTTTGGTGATCGCCTACGTATCCCTGATCAAGCTGCGACGCCAGCGATTGA
GCATGCATATGGCACGGGATTTTTTGTGACCGATGATGGTTATATGCTAACCAATCACCATGTAGTGGCGGGCGCAGACA
AAATTACAGTGACTCTCAATGACAGAACTGAACTGGATGCGACCTTAGTTGGCAGCGATGAGCGCTCGGATGTGGCAGTA
TTAAAGGTCACAGGCAAAAAATTCCCAGCGCTACCGATTGGCGATTCTAATAGCCTAAAAGTCGGTGAACCAGTACTGGC
CATTGGCTCGCCATTTGGTTTCGATTATTCAGCATCAGCAGGTATTGTCAGCGCCAAATCACGTAACTTTTCGCGTGAAA
CCAGTGTGCCATTTATTCAAACCGATGTGGCATTGAATCCTGGTAACTCAGGCGGACCTTTATTTAACCAGCGCGGTGAA
GTGATTGGCATTAACTCACGTATTTTTAGTGGCACCGGTGGTTATATGGGATTGTCGTTCTCCATCCCGATTGATGCGGC
AATGGATGTTTATGAGCAGCTCAAAACCAATGGGAAGGTTGAGCGTGCTTATTTAGGTATTTATCCGCAAGATATCGATC
GCAATCTCGCCGAAGCCTATAACCTAGCGCGTCCGCAAGGGGCGTTACTGACACGCGTGTCGCCTGATTCACCTGCCCAA
AAAGCAGGACTAAAATCAGGGGATATTATTTTACGCTACAATGATGTCCAAATTATGGAAGCCTCTGATTTATTGAACCT
GATCAATCGCGCGCGTCCCAATGATGGCTTTCGTATGCAAATCCAGCGTAATGGTAAGCAATCGCTTGTCACTGGCAAGC
TGAGTGATGCCTCAAATGACATGCAATCACAAAGCCGTGGTCAGCAAAATAACGAGATAAGTCTGGGCTTAGCCTTACGT
AATTTGACCCCAGAGGAACAAGCAGAGCTGGCGTCTGATAATAAAACTGGTGTCTTGGTCACAGCGATTGAACCAACTGG
ATTGGCAGCACGCTCAGGTATATTAGCAGGCGATATCATTACCAACCTACATCAAAAACCGATTAAAACCGTTAATGATG
TTTCGAGTGCGGTGTCGGTATTGCCTAAAAAGGGAGTGGTGACGATCGAAGTTATGCGTCAAGGTATCCCTGGTATTATT
GGATTACGGATAGAGTAG

Upstream 100 bases:

>100_bases
GTACTATTTATTAATCATGAATTAAAATGCCAAGCCGTGCTATAAGTTAATAGCATAGCCACTCACAAAAATTATAAAAA
TCACTTGGATGAGGGATAAG

Downstream 100 bases:

>100_bases
TTAAAGATATTGCTATTACTTGTGGCACAAAAGGACATAAGCGTTTGTTTGCTTGTATCGGCTAGCCAACGATGTGTTGA
CGATTGGTTAAAAGGCTTAA

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MPIDISKSKITIATMQRLLQRSTLAIAVATTMVVGINLNTMPSAQAAVTTADFSGLVQQVTPAVARVNVTKTVSEAELAK
AQTAELLRKFFGDRLRIPDQAATPAIEHAYGTGFFVTDDGYMLTNHHVVAGADKITVTLNDRTELDATLVGSDERSDVAV
LKVTGKKFPALPIGDSNSLKVGEPVLAIGSPFGFDYSASAGIVSAKSRNFSRETSVPFIQTDVALNPGNSGGPLFNQRGE
VIGINSRIFSGTGGYMGLSFSIPIDAAMDVYEQLKTNGKVERAYLGIYPQDIDRNLAEAYNLARPQGALLTRVSPDSPAQ
KAGLKSGDIILRYNDVQIMEASDLLNLINRARPNDGFRMQIQRNGKQSLVTGKLSDASNDMQSQSRGQQNNEISLGLALR
NLTPEEQAELASDNKTGVLVTAIEPTGLAARSGILAGDIITNLHQKPIKTVNDVSSAVSVLPKKGVVTIEVMRQGIPGII
GLRIE

Sequences:

>Translated_485_residues
MPIDISKSKITIATMQRLLQRSTLAIAVATTMVVGINLNTMPSAQAAVTTADFSGLVQQVTPAVARVNVTKTVSEAELAK
AQTAELLRKFFGDRLRIPDQAATPAIEHAYGTGFFVTDDGYMLTNHHVVAGADKITVTLNDRTELDATLVGSDERSDVAV
LKVTGKKFPALPIGDSNSLKVGEPVLAIGSPFGFDYSASAGIVSAKSRNFSRETSVPFIQTDVALNPGNSGGPLFNQRGE
VIGINSRIFSGTGGYMGLSFSIPIDAAMDVYEQLKTNGKVERAYLGIYPQDIDRNLAEAYNLARPQGALLTRVSPDSPAQ
KAGLKSGDIILRYNDVQIMEASDLLNLINRARPNDGFRMQIQRNGKQSLVTGKLSDASNDMQSQSRGQQNNEISLGLALR
NLTPEEQAELASDNKTGVLVTAIEPTGLAARSGILAGDIITNLHQKPIKTVNDVSSAVSVLPKKGVVTIEVMRQGIPGII
GLRIE
>Mature_484_residues
PIDISKSKITIATMQRLLQRSTLAIAVATTMVVGINLNTMPSAQAAVTTADFSGLVQQVTPAVARVNVTKTVSEAELAKA
QTAELLRKFFGDRLRIPDQAATPAIEHAYGTGFFVTDDGYMLTNHHVVAGADKITVTLNDRTELDATLVGSDERSDVAVL
KVTGKKFPALPIGDSNSLKVGEPVLAIGSPFGFDYSASAGIVSAKSRNFSRETSVPFIQTDVALNPGNSGGPLFNQRGEV
IGINSRIFSGTGGYMGLSFSIPIDAAMDVYEQLKTNGKVERAYLGIYPQDIDRNLAEAYNLARPQGALLTRVSPDSPAQK
AGLKSGDIILRYNDVQIMEASDLLNLINRARPNDGFRMQIQRNGKQSLVTGKLSDASNDMQSQSRGQQNNEISLGLALRN
LTPEEQAELASDNKTGVLVTAIEPTGLAARSGILAGDIITNLHQKPIKTVNDVSSAVSVLPKKGVVTIEVMRQGIPGIIG
LRIE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=332, Percent_Identity=31.3253012048193, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI22129776, Length=253, Percent_Identity=34.3873517786561, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI24308541, Length=277, Percent_Identity=32.8519855595668, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI7019477, Length=276, Percent_Identity=33.695652173913, Blast_Score=127, Evalue=3e-29,
Organism=Escherichia coli, GI1789629, Length=314, Percent_Identity=39.8089171974522, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786356, Length=455, Percent_Identity=30.989010989011, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1789630, Length=262, Percent_Identity=34.3511450381679, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24646839, Length=258, Percent_Identity=32.9457364341085, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 51731; Mature: 51599

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDISKSKITIATMQRLLQRSTLAIAVATTMVVGINLNTMPSAQAAVTTADFSGLVQQV
CCCCCCCCEEEHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCHHEEEEHHHHHHHHHH
TPAVARVNVTKTVSEAELAKAQTAELLRKFFGDRLRIPDQAATPAIEHAYGTGFFVTDDG
CHHHHEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHCCCEEEEECCC
YMLTNHHVVAGADKITVTLNDRTELDATLVGSDERSDVAVLKVTGKKFPALPIGDSNSLK
EEEECCEEEECCCEEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCCEECCCCCCEE
VGEPVLAIGSPFGFDYSASAGIVSAKSRNFSRETSVPFIQTDVALNPGNSGGPLFNQRGE
CCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
VIGINSRIFSGTGGYMGLSFSIPIDAAMDVYEQLKTNGKVERAYLGIYPQDIDRNLAEAY
EEEECCEEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHH
NLARPQGALLTRVSPDSPAQKAGLKSGDIILRYNDVQIMEASDLLNLINRARPNDGFRMQ
HCCCCCCCEEEEECCCCCHHHCCCCCCCEEEEECCEEEEEHHHHHHHHHHCCCCCCEEEE
IQRNGKQSLVTGKLSDASNDMQSQSRGQQNNEISLGLALRNLTPEEQAELASDNKTGVLV
EECCCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCEEEE
TAIEPTGLAARSGILAGDIITNLHQKPIKTVNDVSSAVSVLPKKGVVTIEVMRQGIPGII
EEECCCCCHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCEE
GLRIE
EEEEC
>Mature Secondary Structure 
PIDISKSKITIATMQRLLQRSTLAIAVATTMVVGINLNTMPSAQAAVTTADFSGLVQQV
CCCCCCCEEEHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCHHEEEEHHHHHHHHHH
TPAVARVNVTKTVSEAELAKAQTAELLRKFFGDRLRIPDQAATPAIEHAYGTGFFVTDDG
CHHHHEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHCCCEEEEECCC
YMLTNHHVVAGADKITVTLNDRTELDATLVGSDERSDVAVLKVTGKKFPALPIGDSNSLK
EEEECCEEEECCCEEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCCEECCCCCCEE
VGEPVLAIGSPFGFDYSASAGIVSAKSRNFSRETSVPFIQTDVALNPGNSGGPLFNQRGE
CCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
VIGINSRIFSGTGGYMGLSFSIPIDAAMDVYEQLKTNGKVERAYLGIYPQDIDRNLAEAY
EEEECCEEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHH
NLARPQGALLTRVSPDSPAQKAGLKSGDIILRYNDVQIMEASDLLNLINRARPNDGFRMQ
HCCCCCCCEEEEECCCCCHHHCCCCCCCEEEEECCEEEEEHHHHHHHHHHCCCCCCEEEE
IQRNGKQSLVTGKLSDASNDMQSQSRGQQNNEISLGLALRNLTPEEQAELASDNKTGVLV
EECCCCCEEEEEECCCCCHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHCCCCCEEEE
TAIEPTGLAARSGILAGDIITNLHQKPIKTVNDVSSAVSVLPKKGVVTIEVMRQGIPGII
EEECCCCCHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCEE
GLRIE
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]