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The map label for this gene is dapA [H]

Identifier: 93004989

GI number: 93004989

Start: 189068

End: 189973

Strand: Direct

Name: dapA [H]

Synonym: Pcryo_0158

Alternate gene names: 93004989

Gene position: 189068-189973 (Clockwise)

Preceding gene: 93004988

Following gene: 93004990

Centisome position: 6.18

GC content: 46.58

Gene sequence:

>906_bases
ATGAGCACAGCATACGACGATATTAAAACCCGACTACAAGGCTCAATGGTAGCTTTGATAACGCCCATGCTTCGTGACGG
CACGGTCGATTATAAACGTCTGGCAGACCTCATAGATTGGCAGATTGAACAAGGCACACATTGCCTTGTCGCTGTTGGTA
CGACTGGCGAATCTGCAACCTTGTCAATGCAAGAGCATAGCGATGTCATTCGCTATTTTGTACAGCATGTTAAAGGTCGT
GTGCCGGTGATTGCAGGTACTGGTGCGAACAATACGGTGGAAGCCATTAAGCTGACCCAAGATGCCGCAGATGCCGGTGC
AGATTGTGCATTATTGGTCGCCCCTTATTATAATAAGCCGCCACAAGAAGGCTTATATCAACATTACAAAGCCATTGCTG
AAGCTGTTAATATCCCGCAAATGCTGTATAACGTCCCTGGACGCACCGTCGTTGATATCGCGCAAGAAACAGTCGAGCGT
TTAGCGGATATCGATAATATCGTTGCTATCAAAGACGCGACAGGTTCTGTTGCTCGTGGTGAGCAATTAATAAAAGCAGT
GGGCGATCGTCTTGTTGTCTTGTCTGGTGATGATGGTAGTGCCCTTGAGCTGATGAAATTTGGTGGTAAAGGGAATATCT
CTGTGACTGCCAACGTCGCACCAAAGGCCATGAGTGAAACCTTTACAGCAGCCTTGCGCGGTGATTTCGATACCGCAAGT
CAAGTACATGATATCGTTAAACATTTACATCGTGACTTGTTTATCGAATCAAGCCCTATTCCAGCCAAGTACGCTTTGCA
CAAAATGGGTATGATAGATCAAGGTATTCGCCTGCCGCTGGTATGGCTAGCCGAGCAACATCACGCGACGATTGATAGTG
CTTTGGTTCGTGCAAACTTATTATAA

Upstream 100 bases:

>100_bases
TATTTGACAATGAATACTTCAAAATATGCATTGGTACTTGCAAACGACCTATCATGTGATAGCTTTAATCAAAGCTAGGA
TACGAGAGTAAGGCACAGTT

Downstream 100 bases:

>100_bases
AATGATGCGTGTAAATGCTAACTCAGAGAGATAATATGATGAAAGTATCATCAATGACTGCAAAAATGTTCCCTGCTGTA
ATGACGGTCGTGTTGGGTAG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSTAYDDIKTRLQGSMVALITPMLRDGTVDYKRLADLIDWQIEQGTHCLVAVGTTGESATLSMQEHSDVIRYFVQHVKGR
VPVIAGTGANNTVEAIKLTQDAADAGADCALLVAPYYNKPPQEGLYQHYKAIAEAVNIPQMLYNVPGRTVVDIAQETVER
LADIDNIVAIKDATGSVARGEQLIKAVGDRLVVLSGDDGSALELMKFGGKGNISVTANVAPKAMSETFTAALRGDFDTAS
QVHDIVKHLHRDLFIESSPIPAKYALHKMGMIDQGIRLPLVWLAEQHHATIDSALVRANLL

Sequences:

>Translated_301_residues
MSTAYDDIKTRLQGSMVALITPMLRDGTVDYKRLADLIDWQIEQGTHCLVAVGTTGESATLSMQEHSDVIRYFVQHVKGR
VPVIAGTGANNTVEAIKLTQDAADAGADCALLVAPYYNKPPQEGLYQHYKAIAEAVNIPQMLYNVPGRTVVDIAQETVER
LADIDNIVAIKDATGSVARGEQLIKAVGDRLVVLSGDDGSALELMKFGGKGNISVTANVAPKAMSETFTAALRGDFDTAS
QVHDIVKHLHRDLFIESSPIPAKYALHKMGMIDQGIRLPLVWLAEQHHATIDSALVRANLL
>Mature_300_residues
STAYDDIKTRLQGSMVALITPMLRDGTVDYKRLADLIDWQIEQGTHCLVAVGTTGESATLSMQEHSDVIRYFVQHVKGRV
PVIAGTGANNTVEAIKLTQDAADAGADCALLVAPYYNKPPQEGLYQHYKAIAEAVNIPQMLYNVPGRTVVDIAQETVERL
ADIDNIVAIKDATGSVARGEQLIKAVGDRLVVLSGDDGSALELMKFGGKGNISVTANVAPKAMSETFTAALRGDFDTASQ
VHDIVKHLHRDLFIESSPIPAKYALHKMGMIDQGIRLPLVWLAEQHHATIDSALVRANLL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI13540533, Length=238, Percent_Identity=29.8319327731092, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI31543060, Length=238, Percent_Identity=26.890756302521, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=48.7972508591065, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI87082415, Length=268, Percent_Identity=34.3283582089552, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786463, Length=222, Percent_Identity=36.4864864864865, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1789620, Length=267, Percent_Identity=27.7153558052434, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32569; Mature: 32437

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAYDDIKTRLQGSMVALITPMLRDGTVDYKRLADLIDWQIEQGTHCLVAVGTTGESAT
CCCCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
LSMQEHSDVIRYFVQHVKGRVPVIAGTGANNTVEAIKLTQDAADAGADCALLVAPYYNKP
EEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHEEEEHHHHCCCCCEEEEEECCCCCC
PQEGLYQHYKAIAEAVNIPQMLYNVPGRTVVDIAQETVERLADIDNIVAIKDATGSVARG
CHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
EQLIKAVGDRLVVLSGDDGSALELMKFGGKGNISVTANVAPKAMSETFTAALRGDFDTAS
HHHHHHHCCEEEEEECCCCCHHHHEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHH
QVHDIVKHLHRDLFIESSPIPAKYALHKMGMIDQGIRLPLVWLAEQHHATIDSALVRANL
HHHHHHHHHHHHHEECCCCCCHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHCC
L
C
>Mature Secondary Structure 
STAYDDIKTRLQGSMVALITPMLRDGTVDYKRLADLIDWQIEQGTHCLVAVGTTGESAT
CCCHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEE
LSMQEHSDVIRYFVQHVKGRVPVIAGTGANNTVEAIKLTQDAADAGADCALLVAPYYNKP
EEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHEEEEHHHHCCCCCEEEEEECCCCCC
PQEGLYQHYKAIAEAVNIPQMLYNVPGRTVVDIAQETVERLADIDNIVAIKDATGSVARG
CHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
EQLIKAVGDRLVVLSGDDGSALELMKFGGKGNISVTANVAPKAMSETFTAALRGDFDTAS
HHHHHHHCCEEEEEECCCCCHHHHEECCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHH
QVHDIVKHLHRDLFIESSPIPAKYALHKMGMIDQGIRLPLVWLAEQHHATIDSALVRANL
HHHHHHHHHHHHHEECCCCCCHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA